Mleu014065.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrosoma leucophasiata
Gene Symbol
-
Assembly
GCA_036365455.1
Location
JAWQUS010000016.1:7542441-7566867[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 9.2e-05 0.0077 17.4 2.2 1 23 423 445 423 445 0.97
2 20 0.0023 0.19 13.0 2.0 1 21 451 471 451 473 0.94
3 20 2.4e-05 0.002 19.2 5.6 1 23 492 514 492 514 0.98
4 20 0.00022 0.018 16.2 4.7 1 23 520 542 520 542 0.99
5 20 4.2e-05 0.0035 18.5 5.3 1 23 548 570 548 570 0.97
6 20 1.3e-06 0.0001 23.3 5.0 1 23 576 598 576 598 0.98
7 20 8.2e-07 6.8e-05 23.9 2.9 1 23 604 626 604 626 0.97
8 20 0.00012 0.0097 17.1 6.7 1 23 632 654 632 654 0.97
9 20 0.00012 0.0096 17.1 6.5 1 23 660 682 660 682 0.97
10 20 5.6e-07 4.7e-05 24.4 1.9 1 23 688 710 688 710 0.98
11 20 5.7e-05 0.0047 18.1 7.9 1 23 716 738 716 738 0.98
12 20 3e-05 0.0025 18.9 6.4 1 23 744 766 744 766 0.98
13 20 6.8e-07 5.7e-05 24.1 6.6 1 23 772 794 772 794 0.98
14 20 8e-06 0.00067 20.7 3.5 1 21 800 820 800 821 0.94
15 20 0.00014 0.011 16.9 7.5 1 23 865 887 865 887 0.97
16 20 3.3e-06 0.00027 22.0 6.0 1 23 893 915 893 915 0.98
17 20 0.00016 0.013 16.7 10.0 1 23 921 943 921 943 0.97
18 20 9.1e-06 0.00076 20.6 1.9 2 23 950 971 950 971 0.97
19 20 0.0013 0.11 13.7 0.9 1 23 978 1000 978 1000 0.96
20 20 0.0018 0.15 13.4 4.7 1 23 1010 1032 1010 1032 0.99

Sequence Information

Coding Sequence
ATGAATCCTGAACATCACAATATAAATACGGGTGGTGGCCAGCCCCCTGGCAATTCGGagTCTCAGAGTCAAAGAGTTCAAACTGGGCAGCAACAGCAGCAAAGTAGTAATCTGCCTCCAACGACGTCTGCTACCGACTTACGAGTCAACTCGGCCGCTGTAAACGTTGCTTTGTCGAGCGTCGCCAAATATTGGGTGTTTACCAATTTATTTCCGGGACCATTGCCGCAAGTTTCTGTGTACGGCTTGCCAACTGGTGCAAGAATCGAAAATGGGAAACCTGTACAGGAACTTGGGCAGGCTCATGCAAGTATATTGAATGGTGATCCAAATATTATTCTTGGCCATCATGCTGGTCAACCTCAGGTCACTGTGTCTGCAGCGGGACAGCAAATACCTGTTTCGCAAATCATTGCCACACAGTCTGGACAGACACATGAAGCACTGGTGGCCCACAGTCAGCAACAGGAACTGGCAACGCAACAAGCGTCTGCGGCCGGAGCTCAGGTCACAGTTAGCACTGGCCAAACCACCCACCAGCAGGTACCCAATAATCGGGTCGAGTTTGTACAACACCATAACATTGATATGGGCCATCATTCACAACAACACATTTTACAACAACAGCTGATGGCAACCACGCGACCAGATCATGCCAATCAACagATCCAACTGACGGTTAGTGAGGATGGCATCGTTACTGTGGTGGAACCGGGTGGTAAACTCGTGGATAAGGAGGAGCTACATGAAGCTATCAAAATGCCCACGGACCATACTCTCACTGTCCATCAGTTGCAGCAGATTGTTGGACATCatcaaGTAATAGACAGTGTGGTGCGCATCGAACAAGCAACCGGCGAACCGGCGAACATTCTCGTTACACAGAACGCTGATGGCACCACTTCGATAGAAACCAGTGCGGCCTCTGACCCACTCATCGTCAAAGATGAGAAAGTATCCAAAATTGAATCGACGCAATTCGCTATACCCGCTGAAATTAAAGACATCAAGGGTATAGATTTGaaaagtgTTGGAGCAATGGGTATGGAAGGCACAGTAGTAAAGATTTCTGCTGGCGCATCGGAGCACGACCTTCATGCGATGTACAAAGTTAATGTCGAAGACCTATCCCAATTATTGGCTTACCATGAAGTATTTGGTAAACTTAATTCTGAAGGACAAACCCAAGCTAAGgTGATAAGCGAAGTGGAAGTGGAGCCCGGCACGAGTGCAACAATCTCCGAAGCGGAGTCGTCGCCCGGCAGCCACTCGTGCGACATCTGCGGCAAGATATTCCAATTTAGATACCAACTTATTGTTCACAGACGATACCATGGAGAGAGTAAACCTTACACGTGTCAAGTGTGTGGGTGCGCATTCGCCAATCCGGTCGAGCTGTCAAAACACGCGAAATGTCACCTAGCTGGTGACCCAGCAGAGAGACAACAAAAACGTGTGACGCAAGACAAACCTTACGCCTGCACCACTTGCCACAAAACGTTTTCGCGCAAAGAACACCTCGACAATCACGTTCGCAGTCACACTGGAGAAACTCCATACAGATGTCAATTCTGCGCGAAGACATTCACCCGCAAGGAGCACATGGTGAACCACGTGCGCAAGCACACGGGCGAGACGCCGCACCGCTGCGACATATGCAAGAAGAGCTTCACCAGGAAGGAGCACTTCATGAACCACGTCATGTGGCACACCGGTGAAACGCCGCACCAATGTCAAATATGCGGCAAGAAGTATACTAGGAGGGAGCATTTAGTGAACCATATGAGGTCGCATACAAACGATACACCGTTCCGGTGCGAACTGTGCGGGAAATCGTTCACGAGAAAGGAACACTTCACCAATCACATATTGTGGCATACGGGAGAGACACCTCATCGCTGCGACTTCTGCTCGAAAACTTTTACCCGCAAAGAGCATCTGTTGAACCACGTGCGCCAACACACGGGCGAATCCCCGCACCGCTGCAACTTCTGTTCAAAGTCGTTCACGCGCCGCGAACATCTCGTGAACCATGTCCGTCAGCACACAGGCGAGACGCCCTTCCAGTGCGGATATTGCCCTAAGGCCTTCACAAGGAAAGACCATCTAGTGAACCACGTGCGACAGCACACCGGCGAATCGCCGCACAAGTGTTCGTTCTGTACCAAGTCGTTCACGCGCAAGGAGCACCTCACGAACCACGTCCGTCAGCACACCGGCGAATCGCCGCACCGATGCAGCTACTGCGCCAAATCCTTCACTAGGAAAGAACATCTCACCAATCATGTTAGACAGCATACGGGCGAAACACCACACAAGTGTACGTACTGTCCGCGGTCGTTCTCGCGCAAGGAGCACCTCAACAACCACATACGAAGACACACCGGCGACTCCATGCACTACTGTTCCTATTGCAACAAGAGCTTCACTAGGAAAGATCATCTCGTCAATCACGTTCGTTCCCGTGGCCCCAATGCCACAAGGCCCGTGCCATGTCATCTTATTGAGATTCAATTTAGGAACTGGAAAATGTTTTTATCGTATTCTATAATCGAAATGGATTGGCACAGGCAACACACGGGCGAGACGCCGTTCAAATGTACGTTCTGCACGAAGTCGTTCTCTCGCAAGGAGCATCTGACCAACCACGTGCATCTGCACACCGGCACTACGCCCCACAAGTGCCCCTTCTGCACGAAAACATTCTCCAGGAAGGAGCATTTGACCAATCACGTCAGGGTGCACACTGGAGAGTCGCCGCATCGCTGTGAATTCTGCCACAAGACATTCACAAGGAAGGAGCATTTGACGAACCATTTGAAGCAGCACACGGGAGACACACATAATGTGTGCAGAGTTTGCTCGAAACCATTCACTAGGAAAGAACACTTAATTACGCATATAAGGTCCCACAGCTGTGGCGAGCGACCACACACTTGCGGCGAGTGCGGCAAATCATTCCCGCTAAAGGGCAATCTATTATTCCACGAACGATCACACAACAAGGGCGCAAACGCTCCTCGGCCTTATAAATGTGATATCTGCAGCAAGGAATTTGTTTGTAAAGGCCACCTGGTATCTCACCGGCGAACGCACATGGAGACGGACGAGACCGCGCCGGCCGCCGACGCGGCCGCTGACACCGAGGACTGTGGCGAAGGCGACAAGTGCGACAAGGAATCACCCGAGCGGAAACACGATATCAGAGCAACCCCTGAGACCAGAGCAGCCGAGGAAACTGTGACGCAAACTCAATCAAGTAACACTACTGTAATGCAAATAACTAGCCAGCAAGTGCGGGCGTCGACAAGCGCGACGAGCGTGGCGACGGGCACGTTCACACACACGCCGAGCTCGCAGCACCACGCCGGCGCCATCTCCCACCACCCCGTCACCGTCAATTACTAG
Protein Sequence
MNPEHHNINTGGGQPPGNSESQSQRVQTGQQQQQSSNLPPTTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPLPQVSVYGLPTGARIENGKPVQELGQAHASILNGDPNIILGHHAGQPQVTVSAAGQQIPVSQIIATQSGQTHEALVAHSQQQELATQQASAAGAQVTVSTGQTTHQQVPNNRVEFVQHHNIDMGHHSQQHILQQQLMATTRPDHANQQIQLTVSEDGIVTVVEPGGKLVDKEELHEAIKMPTDHTLTVHQLQQIVGHHQVIDSVVRIEQATGEPANILVTQNADGTTSIETSAASDPLIVKDEKVSKIESTQFAIPAEIKDIKGIDLKSVGAMGMEGTVVKISAGASEHDLHAMYKVNVEDLSQLLAYHEVFGKLNSEGQTQAKVISEVEVEPGTSATISEAESSPGSHSCDICGKIFQFRYQLIVHRRYHGESKPYTCQVCGCAFANPVELSKHAKCHLAGDPAERQQKRVTQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCQFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHQCQICGKKYTRREHLVNHMRSHTNDTPFRCELCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCSYCAKSFTRKEHLTNHVRQHTGETPHKCTYCPRSFSRKEHLNNHIRRHTGDSMHYCSYCNKSFTRKDHLVNHVRSRGPNATRPVPCHLIEIQFRNWKMFLSYSIIEMDWHRQHTGETPFKCTFCTKSFSRKEHLTNHVHLHTGTTPHKCPFCTKTFSRKEHLTNHVRVHTGESPHRCEFCHKTFTRKEHLTNHLKQHTGDTHNVCRVCSKPFTRKEHLITHIRSHSCGERPHTCGECGKSFPLKGNLLFHERSHNKGANAPRPYKCDICSKEFVCKGHLVSHRRTHMETDETAPAADAAADTEDCGEGDKCDKESPERKHDIRATPETRAAEETVTQTQSSNTTVMQITSQQVRASTSATSVATGTFTHTPSSQHHAGAISHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00795879;
90% Identity
-
80% Identity
-