Basic Information

Insect: Macrosiphum euphorbiae
Gene Symbol: -
Assembly: GCA_949089665.1
Location: CARXXK010000004.1:48213308-48215229[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1.6 2.1e+02 4.6 0.1 5 19 119 133 118 136 0.80

2 7 0.015 1.9 11.0 7.1 2 23 144 165 143 165 0.97

3 7 4.5e-06 0.00059 22.0 0.2 1 23 171 193 171 193 0.98

4 7 7.4e-07 9.6e-05 24.5 0.8 1 23 199 221 199 221 0.98

5 7 3.3e-06 0.00043 22.5 0.4 1 23 227 249 227 249 0.98

6 7 1.2e-07 1.5e-05 27.0 0.5 1 23 255 277 255 277 0.98

7 7 1.6e-05 0.0021 20.3 2.6 1 23 283 306 283 306 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1.6	2.1e+02	4.6	0.1	5	19	119	133	118	136	0.80
2	7	0.015	1.9	11.0	7.1	2	23	144	165	143	165	0.97
3	7	4.5e-06	0.00059	22.0	0.2	1	23	171	193	171	193	0.98
4	7	7.4e-07	9.6e-05	24.5	0.8	1	23	199	221	199	221	0.98
5	7	3.3e-06	0.00043	22.5	0.4	1	23	227	249	227	249	0.98
6	7	1.2e-07	1.5e-05	27.0	0.5	1	23	255	277	255	277	0.98
7	7	1.6e-05	0.0021	20.3	2.6	1	23	283	306	283	306	0.98

Sequence Information

Coding Sequence: ATGATTAAGACTCCTTATAATTCGAGAATTTCGAAAGTATATGAAGAGGAGTACCTTGATTTatttcaaaaaatattcaagaacAAAAAgaaagataagaaaaaaattattaaggCCGTTACTAGTAAAGAACTTGTGTCcccgcaaaaattaaaaaaacgtaaACGACAGACCACTGATAGGGAATATTCGAAAAACGATTCCCTGCAATCAGTGGACATGGATATGGAAAcatatgatagtaataattatatgggcGAAGACTGTGGaaagaaattagaaattttGGATTCTCGGGACGATCAAACGTCGGAATATCGCACTATGACCGACACAGGTATGTATTTTGgccaatattgtaataaaacatttaacaacGTCAACGGTGTACATAGTCACGAAAATGTTCTCACTGGAAACACTCCTCTCCAGTGCGACGTTTGTTTTAAAACGTTTAGTTGTAAATCTAAATTACATATCCATAAAAGAACGCACACCGGGGAGAAACCATATGCGTGCAATGTTTGTGGCCTATCATTTTCGCAGACAGGAAGTTTAGTTACACATACAAGATCGCACACCGGAGAGAAACCATATGCTTGCAACATTTGTGGAAATTCATTTTCGCAAAAGTCAACATTAGTTCTACATAAAAGAACGCACACCGGGGAGAAACCATATGCGTGCGACGTTTGTGGGAATTCatttactcaaaaaataaatttggttaCCCATACAAAAACACACACCGGAGAGAAACCATATGCGTGCGATGTTTGTGGCCGATCATTTTCGCAAAAAGCAAATTTTGTTAAACACTATAGAATACACACGGGTGAAAGACCATACGAGTGCGGCCATTGTGAAAAAAAGTTCTCATCAAGCAGTGATCGTGCAAGACATACACGAAGAGTTCatatcaaatgtttttaa
Protein Sequence: MIKTPYNSRISKVYEEEYLDLFQKIFKNKKKDKKKIIKAVTSKELVSPQKLKKRKRQTTDREYSKNDSLQSVDMDMETYDSNNYMGEDCGKKLEILDSRDDQTSEYRTMTDTGMYFGQYCNKTFNNVNGVHSHENVLTGNTPLQCDVCFKTFSCKSKLHIHKRTHTGEKPYACNVCGLSFSQTGSLVTHTRSHTGEKPYACNICGNSFSQKSTLVLHKRTHTGEKPYACDVCGNSFTQKINLVTHTKTHTGEKPYACDVCGRSFSQKANFVKHYRIHTGERPYECGHCEKKFSSSSDRARHTRRVHIKCF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00942147;
90% Identity: iTF_00942147;
80% Identity: -