Basic Information

Insect: Macrosiphum euphorbiae
Gene Symbol: -
Assembly: GCA_949089665.1
Location: CARXXK010000001.1:67910350-67914473[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 1.8e-05 0.0024 20.1 2.1 2 23 211 232 210 232 0.97

2 13 0.00019 0.025 16.9 1.4 3 23 240 260 238 260 0.98

3 13 7.7e-05 0.01 18.1 0.1 3 23 268 288 266 288 0.98

4 13 2.5e-05 0.0032 19.7 0.7 3 23 296 316 295 316 0.99

5 13 2.5e-06 0.00032 22.9 0.4 3 23 324 344 322 344 0.98

6 13 1.2e-06 0.00016 23.8 0.4 1 23 375 397 375 397 0.99

7 13 9.8e-07 0.00013 24.1 1.0 1 23 409 431 409 431 0.99

8 13 9.2e-06 0.0012 21.1 2.3 1 23 437 459 437 459 0.97

9 13 6.7e-06 0.00087 21.5 0.9 1 23 465 487 465 487 0.99

10 13 8.3e-05 0.011 18.0 0.4 1 23 493 515 493 515 0.99

11 13 8e-05 0.011 18.1 0.2 1 23 521 543 521 543 0.98

12 13 8.7e-07 0.00011 24.3 0.8 1 23 549 571 549 571 0.99

13 13 0.0012 0.16 14.4 3.7 1 23 577 600 577 600 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	1.8e-05	0.0024	20.1	2.1	2	23	211	232	210	232	0.97
2	13	0.00019	0.025	16.9	1.4	3	23	240	260	238	260	0.98
3	13	7.7e-05	0.01	18.1	0.1	3	23	268	288	266	288	0.98
4	13	2.5e-05	0.0032	19.7	0.7	3	23	296	316	295	316	0.99
5	13	2.5e-06	0.00032	22.9	0.4	3	23	324	344	322	344	0.98
6	13	1.2e-06	0.00016	23.8	0.4	1	23	375	397	375	397	0.99
7	13	9.8e-07	0.00013	24.1	1.0	1	23	409	431	409	431	0.99
8	13	9.2e-06	0.0012	21.1	2.3	1	23	437	459	437	459	0.97
9	13	6.7e-06	0.00087	21.5	0.9	1	23	465	487	465	487	0.99
10	13	8.3e-05	0.011	18.0	0.4	1	23	493	515	493	515	0.99
11	13	8e-05	0.011	18.1	0.2	1	23	521	543	521	543	0.98
12	13	8.7e-07	0.00011	24.3	0.8	1	23	549	571	549	571	0.99
13	13	0.0012	0.16	14.4	3.7	1	23	577	600	577	600	0.93

Sequence Information

Coding Sequence: ATGGTTCTTCGTTGTATATTGTGTTGTAGTGCATCAAATACACACAAAGACGTCAGTTTCCATCGGTTTCCAAAGAATGAAACTGTACGATCAATTTGGATTGACTCTTTAAGTATAAAAGAAGTTGTTAAAGACTGGCATCGAATTTGTAGTTCACACTTCTCTCCAGatcattttacttttaaaaatgaacgGAAGATTTTAAAACTAAGTGCCATTCCAAAAGAgAAAGAAGTGAAAGACGAAGTCGGAAGTTGTGAAACTTCCTTAGACCATGACGTGAATTTAATGAGTAACAgtttaattgAAGTTGATTGTTGTCCTGATATTGACATTTTCAATGAATCTGCACCAAGTACAAGTAAAaggttaAATAGTCCATCAAAAAACACcaagaaaaagaagaaaaaatctAAGgtTGTAAATACTAAAGAAGAAATGTCACAGAAACAATCAAATAAACGTAAACGTCAGACGTCTGATAAAGAATACTCGAAAAACGATACTCCTCAATCAGAGAACACGGATgtggataataattatattgaagaaGACGAcagtaaatattgtaatcaaatgtctGACAATGCCTACGGAGACAAAAATGTTCTCACTGGAAAAACTCCTCTCCAGTGCGACTTTTGCTTTAAAACTTTTGATTACAGATCTAATTTGCTTGTTCATAGAAGAACGCACACCGGTGAAAAACCATATGGGTGCGACATTTGTGGTCTAGCATTTATGATGCACGGTCATTTAGTTAGACATCAAAGAACGCACACAAGGGAGAAACCATATGGATGCGATGTTTGTGGAAAATCATTTCCGGAAGAAGGAACATTGGTTAAACATAAACGAATGCACACCGGTGAGAAACCACATGGGTGCGACGTTTGTGGACTCGCATTTATGATGCAAAGTCATTTAGTTAGACATCAAAGAACGCACACCGGTGAGAAACCATATGGATGCGATGTTTGTGGAAGATCATTTTCGGAAAGAGGAAATTTGGTTAGACATAAAAGAACGCATCCAACATCTAATAATGCCTATAGTGATAAAAATGTTCTCACTGGAAACACTCCTCTCAAATGTGACTTAACCGTCACAGGTGAGAAAAAATATGAGTGCGATGTTTGTGGCCGATCATTTTCGGAAAAAGGAAGTTtagttaaacataatagaaCGCATGAAACATCTGACATTGCCTACGGTGAGAAAAAATATGAGTGCGATGTTTGTGGACTAGCATTTCACACGCTAAGTAATTTAGTTAGACATCAAAGAAAGCACACCGGGGAGAAACCATATGCGTGCAATTTTTGTGGAAAATCATTTTCGCAGAAAAATCATTTGGATGTACATAATAGAATACACACCGGGGAGAAACCATATGTGTGTGCCGTTTGTAGCCTTTCATTTTCTGATAAAAAACATTTGGTTATACATATTAGAAAGCACACCGGAGAGAAACCATATGTGTGCGACGTTTGTAGCCAATCATTTCCGGAAAAAAGACTTTTGGTTACACATACTAGAACGCACACCGAGGAGAAACCATATGCGTGCGTAGTTTGTGGAAAATCATTTTGGCAGCAATATAATTTGGTAGTACATAATAGAACACACACCGGGGAGAAACCATATACGTGCAATGTTTGTGGCCGATCATTTTCGGAAAAAGGAAGTTtagttaaacataatagaaCGCACACAGGCGAACGACCATACGAGTGCAGTCAGTGTggaaaaaagttcaaaacaagCCGAGACTGTAAAAGACATACACTAGGTGttcatgccaaaaaaaaaaaaaaaaattga
Protein Sequence: MVLRCILCCSASNTHKDVSFHRFPKNETVRSIWIDSLSIKEVVKDWHRICSSHFSPDHFTFKNERKILKLSAIPKEKEVKDEVGSCETSLDHDVNLMSNSLIEVDCCPDIDIFNESAPSTSKRLNSPSKNTKKKKKKSKVVNTKEEMSQKQSNKRKRQTSDKEYSKNDTPQSENTDVDNNYIEEDDSKYCNQMSDNAYGDKNVLTGKTPLQCDFCFKTFDYRSNLLVHRRTHTGEKPYGCDICGLAFMMHGHLVRHQRTHTREKPYGCDVCGKSFPEEGTLVKHKRMHTGEKPHGCDVCGLAFMMQSHLVRHQRTHTGEKPYGCDVCGRSFSERGNLVRHKRTHPTSNNAYSDKNVLTGNTPLKCDLTVTGEKKYECDVCGRSFSEKGSLVKHNRTHETSDIAYGEKKYECDVCGLAFHTLSNLVRHQRKHTGEKPYACNFCGKSFSQKNHLDVHNRIHTGEKPYVCAVCSLSFSDKKHLVIHIRKHTGEKPYVCDVCSQSFPEKRLLVTHTRTHTEEKPYACVVCGKSFWQQYNLVVHNRTHTGEKPYTCNVCGRSFSEKGSLVKHNRTHTGERPYECSQCGKKFKTSRDCKRHTLGVHAKKKKKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00941074;
90% Identity: iTF_00941074;
80% Identity: iTF_00941074;