Basic Information

Insect: Macrophya annulata
Gene Symbol: Zfy1
Assembly: GCA_963924015.1
Location: OZ001263.1:959595-966191[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0037 0.39 11.9 5.4 1 23 168 191 168 191 0.97

2 18 0.0093 0.96 10.7 1.2 2 23 207 228 206 229 0.95

3 18 6.7 6.9e+02 1.7 3.7 1 23 235 257 235 257 0.97

4 18 0.042 4.4 8.6 0.5 2 23 263 284 262 284 0.97

5 18 8.6 9e+02 1.3 1.5 6 23 549 566 547 567 0.81

6 18 0.0027 0.28 12.4 0.8 2 21 578 597 577 598 0.93

7 18 7.8 8.1e+02 1.5 0.6 2 23 859 880 858 880 0.93

8 18 0.73 76 4.7 0.1 3 23 897 917 895 917 0.94

9 18 0.051 5.3 8.3 0.3 1 23 925 947 925 947 0.98

10 18 0.74 77 4.7 1.0 2 23 1044 1065 1043 1065 0.93

11 18 0.54 56 5.1 1.8 3 23 1077 1097 1075 1097 0.93

12 18 0.0039 0.41 11.9 0.2 1 23 1174 1196 1174 1196 0.98

13 18 0.044 4.6 8.5 0.3 1 23 1268 1290 1268 1290 0.97

14 18 5.6e-05 0.0059 17.6 0.5 1 23 1296 1318 1296 1318 0.97

15 18 0.0065 0.68 11.2 2.6 1 23 1371 1393 1371 1393 0.97

16 18 0.0018 0.19 12.9 1.7 1 23 1399 1421 1399 1421 0.99

17 18 1.3 1.4e+02 3.9 0.1 2 23 1517 1538 1516 1538 0.97

18 18 7.6 7.9e+02 1.5 0.2 3 23 1547 1567 1546 1567 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0037	0.39	11.9	5.4	1	23	168	191	168	191	0.97
2	18	0.0093	0.96	10.7	1.2	2	23	207	228	206	229	0.95
3	18	6.7	6.9e+02	1.7	3.7	1	23	235	257	235	257	0.97
4	18	0.042	4.4	8.6	0.5	2	23	263	284	262	284	0.97
5	18	8.6	9e+02	1.3	1.5	6	23	549	566	547	567	0.81
6	18	0.0027	0.28	12.4	0.8	2	21	578	597	577	598	0.93
7	18	7.8	8.1e+02	1.5	0.6	2	23	859	880	858	880	0.93
8	18	0.73	76	4.7	0.1	3	23	897	917	895	917	0.94
9	18	0.051	5.3	8.3	0.3	1	23	925	947	925	947	0.98
10	18	0.74	77	4.7	1.0	2	23	1044	1065	1043	1065	0.93
11	18	0.54	56	5.1	1.8	3	23	1077	1097	1075	1097	0.93
12	18	0.0039	0.41	11.9	0.2	1	23	1174	1196	1174	1196	0.98
13	18	0.044	4.6	8.5	0.3	1	23	1268	1290	1268	1290	0.97
14	18	5.6e-05	0.0059	17.6	0.5	1	23	1296	1318	1296	1318	0.97
15	18	0.0065	0.68	11.2	2.6	1	23	1371	1393	1371	1393	0.97
16	18	0.0018	0.19	12.9	1.7	1	23	1399	1421	1399	1421	0.99
17	18	1.3	1.4e+02	3.9	0.1	2	23	1517	1538	1516	1538	0.97
18	18	7.6	7.9e+02	1.5	0.2	3	23	1547	1567	1546	1567	0.79

Sequence Information

Coding Sequence: ATGGCCGATTCGCTGCCCCGTTTACGAGCACTACGTCCTCGACCTCTACCACAGGCACCCCCACCCACGGTCATTAACCCCGTGATCGAATTAAACCACGAGGAAATCGTCGAGGATGAAGACGAGCCGATGGAACAGGTACAAGAACAGGAACAAGAACCAGATTCAAATGAAGAGGTCGGGAGAAGTAGGAGAAGAGACGTTGTCGTTCAGGGAGCGGATATTAGCGACGACGAAGTGACGGTAATGGccgacgaagacgaagacgaggATGACGCGGCCgttgatgatgacgatgaagagcctgaagaggaggaggacgaCGATGACGAAGAGGGGAAATTGGTCATCAAAGAAGAGCCGGTCGAGACACCGGCAATCGACAAGGAAGAGGGtactaaaatttatgaatgtaCCACCTGCAAACCTTCCAAAGAATTACTCAGCCTGAAAAGCTACCttcatcatttaaaaaaagaacacaaaCAAAGGGTGAGATGTTACGAGTGTCCGCACTGCGATTTCGTATGTCAACACGCTAAGAAGTTACAGCGTCATTTCCGTGTAGCTCACGAAGATCTTCAGGATAAAATAGCGACGGAATCTGCTGAAAGAAGCCGATGCCCGATGTGCGCACACGTTGCCGCGAATCAACGTGATTTAGAAACTCATCAACGTGTTCATCATCTAAAAAGACGATTTTTTCGATGTGCAAAATGCTCATATGTTACCCACGTCAGAGCGAGATATACGAAACACGTTAAATATCACTCCATGCCTATGATCAAGTGCGATGcctgcgatttccgaactccTTACAAGTGGAATTTGGATCGGCATACTAGAAACCACGGGGGAGGCGGAGCCTTTCAATGTCGTGCCTGCAATTTCACAGCTGATATCAGACAGAGCCTCACAGTTCATGAAATGAATCATCATGATCCACCCGTTGGACAGCCACACCGAAAACCCAACAATCCTTGCGAGAGGAAACCAAGAAATAGCCCAAAACGATATAATCAGGTTGGAGCGAGCGATTTTCGAGAAAACACTCCAAAATCATCTGCGAATTCTACACCTGTCAAGTCTGGGAGTCCAAGTAAGGCTTCTACTCCTAGAAAATCTCTAACTCCAGACAAACGGGATCTCCGTGATGAAACGAGCAGCGTTATAGCCGGTGCAGAATGCATAGCTTtaaaatgtgaagaaaaagGTTGCCAATTCATCACTGCATGGGATTCTGAGATGCAACGTCACCTCGCGGAATCCCATGCCCCTCTGCTCATCAGTAAACCTAGGAAACCTTTGCCTATGCTTATACCGCTCGGCACAACCAGTTCTCCTAAGCCAAATAGCATTGGTGGCGGAAGCCGAGGTGCCACAACGCTTTTGAGGGTACCGAGGGTCAGAGTCAGGCCGGAGTTGGCGCAAATTGCAAGAGACACAGAGATGGCGAGACTGTATGGAGAACAAGAGAATTTAGCTACCAAGAGGGAGTTGAGTGGTAGCGGGGACTCGTTTGAAAAGAAGAACGCTTCGTTTTTTGACAAGTTGAAGGAACGGTTGATGACTAGTACCTCGAGTAATGGAGGAAGATTGGAAGCTGTTAGCGGGAGCACAGGTGCTATAGATTTGAAATGCTGGTGTACTTTCGAAGCCAAGAACATGGAGGAGTTGTCCAATCATCGACGGACCCACCATGCGGCTCTTAGCGTGTCCCTTGGCTCCTCTAGATGTCCTAAATGCCGTAGGCGGTGCAAAAGCTCAGCCGATCTACAGGCACATGTACAAATCTGCCAATCTGGTGTTGAGGAGACTCCTATTAACGATAATTCACAAATTTACCTAGAAGATCGTCCTACGGCTTATCGCGGGGAATATACATTCCCTTTCCAAGTGGACTGGGACTCAAGTTTTGCGGGACTCAATTCTTCAGGCTCGTCGGTGGAGAGTGGCTCAACACAGCAGAGTGGTCGCAGAGTATTCAAATGCCCTCATTGCGCTTTCTGGGCTTCTACGGCGTCTCGTTTTCATGTGCACATCGTCGGCCATTTGAATCGGAAACCGTTTGAATGCTCTTTGTGTTCTTATCGATCAAACTGGCGATGGGACATCACCAAACATATTAAACTTAAAGCAGCTAGAGATCCTGCACACGCATCTGCTCGCGTTCTTATGACTGATGAAACTGGGCgccgaaattattcaaaatataacaaatatcTCGCTCAGGTGCAGCAGCAACAGTTGCAGTTGTCTGACGAGCACGGGCTGGATGAACCACCATCAAAAATGCTTTTGACTGATGATTCTGAATATGGGCTTCCCCCGGAGTTAACACCGGCACCTAGTCCCTCATCAATGGGTCTTAGTTCATCAATAGAAGTTTGCTCACTACCCGCGAGACCTCCGCCACCCCTCAAAGCGGCAAATCGTGGCCAAGGGCAATCTTTATTGAAGACTAGTCCAGGTTCCGCCTTATCCACCTCTACCACGTCTGTAACAATATCTGTACCCCCTACCACTGCTAGTACCGGGGCTAATAACTCGGAAGAAGCTAAACGTACATTATGGAAATGTAAAAGGTGTAATTATAGAGATTCCAGCAAAGAAGCAGTCTTGCTACACGTCAAATCTCACTACGAAGCTTCTGCACAGACATCTGACAACGAAAAGaaagTTTTTGGGTGTGGGGATTGTCCATTCGCAGCTTCCACTGCCGCATCCCTTGCTGCGCATCGCGTACATCATCGACCAAACCTTGGAGCAATCTTTAAATGTTATCTCTGCCCGTTTTACGTCAGCACCAAAGTagaaCTGCTGGAGCATGCTAGGCTCCATGGTGAAGAATTGGCTGCCGAACATCAGCGGAATATAGAAACAGAAAGTCTCCCCGTCAAACGGAAGTATCAACGTCTATTACCTGCAAGTAAAACTAAGGCTGAGGATTCCCCGGTTGAGGAAATAGTTCGTGTGTCTTCAGCCTCAGCTTCTAATCCAACATCTCCAAGATCAAAGGCACCAATAAGCGGCGGGGTTCCTCCGCCCCTGTTACTGGACACTCGAGCTCTGCCTGACGCTCCTTTGGTCTGGGTCTCTCGTCCCGACGGCAGCCTGTCTAAAATGTTGAAGTGTCGGCATTGTCCCCACGTCGCTTCTCGCCGAGCAGAGGTGCGGGACCACGAAGGAATGCACATCTCTCCACCGACTCAGGGGATTTTAATTAACTGTACAGACTGTAACTTCACTTGCACCCGTCGAGATGTTATGGATTCTCACACTGCAATGCATTCCGGTGTTTTGGGTACTGTGCATTGCCTTGTGGATGAAGGTCGCCCAGATAATCAACAGCTAAACGATTTAGCCACACTTTTAGGACTACCTCAGCCGCCTGTTCTAGGTTCTGAACCAGATCTACGAGACTCTAGACTTGTACATTGCTGCGGTAAATGTCCCGCGAGATTTTTATGCGAAAAAGAACTTCGAATACATTTGCGGTACCATTCGACAGAGCTCGCATATTCTTGTCAGTGGTGTTCATACGCTGCTAGACAACCTGCCCATCTTCTTGCTCACCAAAAAGCTCACTCTCCTGAATATCAGGAGCGGACTCGGTACCTACTCTCATTGTATGGTCACTCTCAACGGCACCCGCCGCCAACTACCGCTTGCGTCGAAGCCAACAATCATTCGTCATCTGCCGCCGGAATTGGCGGGGTTGCTTGGATCGTTGTAGAAATTAATTCGGGTCCTGGTACTCATTCTGGTGGTGTTAGCAGTCAAGATAATGGAAATCAGGTCTTTACGTGCGCCAAATGTCCGGCTAGGTATTTTAAACTTGACGCTTTGGAATATCACATGACTTTGCACGGGACAAATAACAGATTCAAATGCTCCGAGTGTGATTATTCTTCTAAAACTGCACAGAATTTGGCCAAACATCAAGTTGTTCATCGACGGCATGCTGAAACTAACGAAACTACAACTACGGCTAATGTTGCGGGAAGATTGCCACCTCCGCCTGATCCGCAATTCGGTATTTTGATGCGTGGTAATCCGAATTTCGTTTATCCTGGCTATTTAAGAAATGGACGTCTCAAGGAGAAACGATACAAATGTCACAAGTGCCCGTCAGCTTTTGAAAAACGTGAACAGTACAGAGTCCATCTTACTCTGCACGGAGCAAAGCAGAGGTACCGTTGCGATACTTGCGACTATTCTGTTAAATATTACGCAAATTACGTTCAACATCTTAAAAAACATCAGGCAAACGCGGAGGCTCAGGCATCTAAACGGCAGTATGAGGACGACGCGATTTCAATAGACAGCGACATAACTCCCGAACAAACTGCAATCTTAATATCTAGACCAGGAAAGTCTCTGTCCAAATCTTTAACGGTCGTCTCATCCGCGGCTAATAACAACATCGGCAATTCCGCAATTGGTTCAGCAGCAATTGTCGTTTCTAATCAGGATAAACAATCCCTAATGCTTATGCAGAGAAAAGGTGTTTTGCCAGGGTCTAACGATATTGACGAAGAGTCAATACGATGTCAGAGCTGTCCGTTTGGCACTCCGGATAAAGAGGCAATGGATGCTCACAAGAGGAGACACGGCATTGAGAGAATGACGCCGCCTTGTCCACATTGCGATTACGTTCCACGAAAGGACGAAAATGCCAGTGAACACGTCAGGCTGCATTTCACAAGACTTTACAAGCCTGAATCTTATTTAATTGCTGAATTATTGGCTCTACGTGTTCATCCTTTGAATAAAACTAAGATTGGAAGACAGGATAAGAACACCGATGAGAATGACGAACTTCTATTTAAGGAATGTGTTGATGGAAGGTTTCTTCCTGTTCTAGACGCCACTCCATTGGCACACGCTTTACCCTCGACTTCTACACTGGCTAATCAAGAGAAAGTCATTGTTGACCCTAATACTGGCGAAGCAAGGCATGCCCTTGCGACTTAG
Protein Sequence: MADSLPRLRALRPRPLPQAPPPTVINPVIELNHEEIVEDEDEPMEQVQEQEQEPDSNEEVGRSRRRDVVVQGADISDDEVTVMADEDEDEDDAAVDDDDEEPEEEEDDDDEEGKLVIKEEPVETPAIDKEEGTKIYECTTCKPSKELLSLKSYLHHLKKEHKQRVRCYECPHCDFVCQHAKKLQRHFRVAHEDLQDKIATESAERSRCPMCAHVAANQRDLETHQRVHHLKRRFFRCAKCSYVTHVRARYTKHVKYHSMPMIKCDACDFRTPYKWNLDRHTRNHGGGGAFQCRACNFTADIRQSLTVHEMNHHDPPVGQPHRKPNNPCERKPRNSPKRYNQVGASDFRENTPKSSANSTPVKSGSPSKASTPRKSLTPDKRDLRDETSSVIAGAECIALKCEEKGCQFITAWDSEMQRHLAESHAPLLISKPRKPLPMLIPLGTTSSPKPNSIGGGSRGATTLLRVPRVRVRPELAQIARDTEMARLYGEQENLATKRELSGSGDSFEKKNASFFDKLKERLMTSTSSNGGRLEAVSGSTGAIDLKCWCTFEAKNMEELSNHRRTHHAALSVSLGSSRCPKCRRRCKSSADLQAHVQICQSGVEETPINDNSQIYLEDRPTAYRGEYTFPFQVDWDSSFAGLNSSGSSVESGSTQQSGRRVFKCPHCAFWASTASRFHVHIVGHLNRKPFECSLCSYRSNWRWDITKHIKLKAARDPAHASARVLMTDETGRRNYSKYNKYLAQVQQQQLQLSDEHGLDEPPSKMLLTDDSEYGLPPELTPAPSPSSMGLSSSIEVCSLPARPPPPLKAANRGQGQSLLKTSPGSALSTSTTSVTISVPPTTASTGANNSEEAKRTLWKCKRCNYRDSSKEAVLLHVKSHYEASAQTSDNEKKVFGCGDCPFAASTAASLAAHRVHHRPNLGAIFKCYLCPFYVSTKVELLEHARLHGEELAAEHQRNIETESLPVKRKYQRLLPASKTKAEDSPVEEIVRVSSASASNPTSPRSKAPISGGVPPPLLLDTRALPDAPLVWVSRPDGSLSKMLKCRHCPHVASRRAEVRDHEGMHISPPTQGILINCTDCNFTCTRRDVMDSHTAMHSGVLGTVHCLVDEGRPDNQQLNDLATLLGLPQPPVLGSEPDLRDSRLVHCCGKCPARFLCEKELRIHLRYHSTELAYSCQWCSYAARQPAHLLAHQKAHSPEYQERTRYLLSLYGHSQRHPPPTTACVEANNHSSSAAGIGGVAWIVVEINSGPGTHSGGVSSQDNGNQVFTCAKCPARYFKLDALEYHMTLHGTNNRFKCSECDYSSKTAQNLAKHQVVHRRHAETNETTTTANVAGRLPPPPDPQFGILMRGNPNFVYPGYLRNGRLKEKRYKCHKCPSAFEKREQYRVHLTLHGAKQRYRCDTCDYSVKYYANYVQHLKKHQANAEAQASKRQYEDDAISIDSDITPEQTAILISRPGKSLSKSLTVVSSAANNNIGNSAIGSAAIVVSNQDKQSLMLMQRKGVLPGSNDIDEESIRCQSCPFGTPDKEAMDAHKRRHGIERMTPPCPHCDYVPRKDENASEHVRLHFTRLYKPESYLIAELLALRVHPLNKTKIGRQDKNTDENDELLFKECVDGRFLPVLDATPLAHALPSTSTLANQEKVIVDPNTGEARHALAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00060728;
90% Identity: iTF_01413797;
80% Identity: -