Basic Information

Insect: Macrophya annulata
Gene Symbol: ZEB2
Assembly: GCA_963924015.1
Location: OZ001258.1:20315039-20317773[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0073 0.76 11.0 0.2 2 23 298 319 297 319 0.94

2 8 0.16 17 6.8 1.0 1 22 397 418 397 418 0.92

3 8 5.6e-06 0.00058 20.8 5.4 1 23 431 453 431 453 0.96

4 8 0.0045 0.47 11.6 0.3 1 23 459 481 459 481 0.97

5 8 3.8e-05 0.0039 18.2 0.8 1 23 487 509 487 509 0.94

6 8 0.0021 0.22 12.7 3.3 3 23 517 537 515 537 0.97

7 8 0.00043 0.045 14.9 2.0 1 23 543 565 543 565 0.98

8 8 4.6e-05 0.0047 17.9 0.8 1 21 571 591 571 592 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0073	0.76	11.0	0.2	2	23	298	319	297	319	0.94
2	8	0.16	17	6.8	1.0	1	22	397	418	397	418	0.92
3	8	5.6e-06	0.00058	20.8	5.4	1	23	431	453	431	453	0.96
4	8	0.0045	0.47	11.6	0.3	1	23	459	481	459	481	0.97
5	8	3.8e-05	0.0039	18.2	0.8	1	23	487	509	487	509	0.94
6	8	0.0021	0.22	12.7	3.3	3	23	517	537	515	537	0.97
7	8	0.00043	0.045	14.9	2.0	1	23	543	565	543	565	0.98
8	8	4.6e-05	0.0047	17.9	0.8	1	21	571	591	571	592	0.95

Sequence Information

Coding Sequence: ATGATGGAGAAAACAAGTTTTGAGGACATTGAGACATCGAGTCAAATtgaaagcaaaaaagaaaccgAATCAATCGCAGAAATAAATTCtgttttctatgaaaaagatGGGAACCCAGTAGACACAGGCTCTGAGATAAACGAGGATTTTTGTGCGGTAAAAGAGAGGATCAAATATGAAAAGACTGAAAGAGCTGAGAATATTGAAACCGTCCATACAGAATCAACCACATTatctgaaaattgtgaaattccaAAATCAGAACAGAGCTTGgaattttctagaaaaataTCCGAATTCACTGATTATACACCTTTGATGTCACTCTGTAGACTTTGCGCAACTCGAAAGAAACTTGAACTGTGTTATGAATTTCATAAAACTGTTAAAGCAGCTAAGAAACAGTTTCTCACTTTCAATGACGGACAATGCAAtgaggaaaaatataaatctttcTCCTACCAAGATGCACATAATAACATAGTCAAGCCACAGACCATTCTGCAAGAACTGTCCGAAACAGATGCTGAAACTCTAGAAAACAGCACTCGTTTATCAAATTCAATGCTGTGGAAAGAAACGTACTATACGAACAAACCAAACGAAGAGAGCAAGACGGAAAGTTCAAGCGATGAGGATCAGAGTACCTTCAATTCTTTACAGACTGATCCCTTGGAAATATTGAATGATATTGAAGAAACACTAGGATTTGAATTGAACCCTAGTACTCCCAAATCCTATTTCTCGCTCATCGATTATCGCTATCAGGACTCTAATAACCCGAACGAAGAGTCCAGAAATGATGAGAGCGATGATGATATTGTCATTCGGGAAGAGGTGTTTGATAAGCGAACGTCAACTGAGCAAAGAATTATTGGtcatgaattaataaaatgcCAAGATTGCACAGAAACTTTTGAGACTCTAAATCAATGGCTAGCACACTCGAGCATTCATGCCTCGAAAGGCTACTTCCTTCGAACTAGAAAAAACTGCAATAAACACAGGCTGGAAcatgaagaagatgaagatttGAGAAGAGGAGTGCAGACCAATAGCGAGACGTCTCCATGTCAGCACATGCTCACTGTACACAAACAGCAAAAGAAATCATCTCCCAACATATGTGAAAGAAAGTCAAGTGCCTCGGGACAACCTATTACTCTTCAATGTAAACTTGATCGTAGTTTCGAATGCAAATTATGCAACAAAAGATATTGGTCAAATCATATACTGGAAATGCATATGAAGACTGACTGCAGTGGGCCACTAGTATCAACGAAAAAGAGATTTTTATGCACGTATTGTAAACGAAGATTCCGACAAAAAGTACATTTAACAAAGCATCTAAGAATACACACTGGAGAACGTCCATATGACTGTGACTTGTGCGGTAAAATATTCGTCGCTAAAGACAAGAGAGATTCTCATCGTAGAATACACATGGGTGAAAGACCATATAAATGTTCAAAATGCGAAAAGAAGTTTACTACGTATTCTGGACTGGTGGCGCATTCTGTTGTTCATTCGGATGCTAAGCCATATGGTTGTTACCTCTGTCACTTGTCGTTTAAACGATCATACGCAAGAAATCTACATATGCGAAAACACACTGGAGACCATCCCTATGACTGTGACTTGTGCAGTAAAATGTTCACCCGCAAAGACCTGAGAGATAATCATCGTAGATCACATACGGGTGAAAAACCGTTCAAATGTTTAAAATGCGAAAAGAGGTTTGCCAGTTCTTCTGGACTTCGGCATCATGTTAACATCGTTACCACCTGTATTACTAATCGTTCAAAAGATTAA
Protein Sequence: MMEKTSFEDIETSSQIESKKETESIAEINSVFYEKDGNPVDTGSEINEDFCAVKERIKYEKTERAENIETVHTESTTLSENCEIPKSEQSLEFSRKISEFTDYTPLMSLCRLCATRKKLELCYEFHKTVKAAKKQFLTFNDGQCNEEKYKSFSYQDAHNNIVKPQTILQELSETDAETLENSTRLSNSMLWKETYYTNKPNEESKTESSSDEDQSTFNSLQTDPLEILNDIEETLGFELNPSTPKSYFSLIDYRYQDSNNPNEESRNDESDDDIVIREEVFDKRTSTEQRIIGHELIKCQDCTETFETLNQWLAHSSIHASKGYFLRTRKNCNKHRLEHEEDEDLRRGVQTNSETSPCQHMLTVHKQQKKSSPNICERKSSASGQPITLQCKLDRSFECKLCNKRYWSNHILEMHMKTDCSGPLVSTKKRFLCTYCKRRFRQKVHLTKHLRIHTGERPYDCDLCGKIFVAKDKRDSHRRIHMGERPYKCSKCEKKFTTYSGLVAHSVVHSDAKPYGCYLCHLSFKRSYARNLHMRKHTGDHPYDCDLCSKMFTRKDLRDNHRRSHTGEKPFKCLKCEKRFASSSGLRHHVNIVTTCITNRSKD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -