Basic Information

Insect: Macrophya annulata
Gene Symbol: -
Assembly: GCA_963924015.1
Location: OZ001263.1:13467330-13475475[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 2.8 2.9e+02 2.9 0.9 2 23 325 346 324 346 0.83

2 20 0.47 49 5.3 0.7 1 23 352 374 352 374 0.87

3 20 1.2 1.2e+02 4.1 2.0 2 23 439 460 438 460 0.90

4 20 1.3 1.4e+02 3.9 0.1 2 15 467 480 466 488 0.77

5 20 9.2 9.6e+02 1.2 3.6 2 23 554 575 553 575 0.88

6 20 0.016 1.7 9.9 0.4 1 21 581 601 581 603 0.83

7 20 0.32 34 5.8 0.1 2 17 617 632 617 636 0.82

8 20 0.011 1.2 10.4 1.1 2 23 646 668 645 668 0.93

9 20 0.00019 0.02 16.0 0.9 3 22 677 696 675 699 0.90

10 20 0.023 2.4 9.4 0.0 1 20 702 721 702 723 0.93

11 20 3 3.2e+02 2.8 1.0 2 12 1364 1374 1363 1385 0.86

12 20 0.0097 1 10.6 0.5 1 23 1391 1413 1391 1413 0.94

13 20 0.62 64 4.9 0.6 1 10 1426 1435 1426 1448 0.87

14 20 0.071 7.4 7.9 0.1 2 23 1456 1478 1455 1478 0.96

15 20 8.7e-05 0.009 17.1 2.5 1 23 1484 1506 1484 1506 0.95

16 20 1.1e-05 0.0011 19.9 1.1 1 23 1515 1537 1515 1537 0.98

17 20 0.00084 0.087 14.0 3.0 1 23 1543 1565 1543 1565 0.98

18 20 0.00065 0.068 14.3 0.2 1 23 1571 1593 1571 1593 0.97

19 20 0.0002 0.021 15.9 3.5 1 23 1599 1621 1599 1621 0.99

20 20 0.011 1.2 10.4 1.2 1 23 1627 1650 1627 1650 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	2.8	2.9e+02	2.9	0.9	2	23	325	346	324	346	0.83
2	20	0.47	49	5.3	0.7	1	23	352	374	352	374	0.87
3	20	1.2	1.2e+02	4.1	2.0	2	23	439	460	438	460	0.90
4	20	1.3	1.4e+02	3.9	0.1	2	15	467	480	466	488	0.77
5	20	9.2	9.6e+02	1.2	3.6	2	23	554	575	553	575	0.88
6	20	0.016	1.7	9.9	0.4	1	21	581	601	581	603	0.83
7	20	0.32	34	5.8	0.1	2	17	617	632	617	636	0.82
8	20	0.011	1.2	10.4	1.1	2	23	646	668	645	668	0.93
9	20	0.00019	0.02	16.0	0.9	3	22	677	696	675	699	0.90
10	20	0.023	2.4	9.4	0.0	1	20	702	721	702	723	0.93
11	20	3	3.2e+02	2.8	1.0	2	12	1364	1374	1363	1385	0.86
12	20	0.0097	1	10.6	0.5	1	23	1391	1413	1391	1413	0.94
13	20	0.62	64	4.9	0.6	1	10	1426	1435	1426	1448	0.87
14	20	0.071	7.4	7.9	0.1	2	23	1456	1478	1455	1478	0.96
15	20	8.7e-05	0.009	17.1	2.5	1	23	1484	1506	1484	1506	0.95
16	20	1.1e-05	0.0011	19.9	1.1	1	23	1515	1537	1515	1537	0.98
17	20	0.00084	0.087	14.0	3.0	1	23	1543	1565	1543	1565	0.98
18	20	0.00065	0.068	14.3	0.2	1	23	1571	1593	1571	1593	0.97
19	20	0.0002	0.021	15.9	3.5	1	23	1599	1621	1599	1621	0.99
20	20	0.011	1.2	10.4	1.2	1	23	1627	1650	1627	1650	0.95

Sequence Information

Coding Sequence: ATGGCTAAGAGAAAATTACGACTCGAAATACAACAGAGCGACGAACACGGAGAATGTGGAGGTCCGAAAGTACCTCGATGGTACGGTCAACATTCCATCACCACAAAAGATATCAcagaaaaaaatcagcAAAGTATAAATTCGGAAAATTATGTCCGTGAGATTTCTAACTCTGATTTACAACATGTGAAGCAAGAATTAAAAGAGCACGTGGAACCAGCCACAGAATCTACAATTTCGTTTAAAGATGTTGTGAAAGTAACATCAGAGGGATACAAATTAGAAACATTAGAGCCAGACGTGGAAGAAGAATTACATACAGAAATAGAAGAGACAAGATCTGAGAACAGAAATCTGGctggaaaatttgaaacagttTATATAGACTCAGCAATGTTATGTGAAAATGATGAACCTCCTAAATCTGGGCAAAGCTCAGAAATTTCTGGTTCTATATTCCAATCGACAAACGATACAACTTTACTATGTAGACTTTGCGCAACTCAGAGAAAGgatatgatttatatttttgaacgtAACGAagcttataaaaatataataaaaaagattcaagATTGTTTACCTATCTTGGTAACAAAGACTGACACATTTCCTAAACAAGTTTGCAGATTGTGcttagaaaaattagaaatgttTCACAAATTTCACAAAACTGTAATAGAGGCTGAAAAACAGTTTAATAATTTGGGTGAAAAAATGTCTGAAGCATTGAAAAATACAGATAAAAATGTTCAGACTTCACTGCCGCAGAATGAACAAATGGATTCTAAAAAACACAGCAAAAAATTAGTATCCGATAAGAAATTGTGTTCTCTTCCATTAACTTTCAAAAGCCCTGAGATTTTGAATAACCCAAAAGAATCAGTTAACAAAACCAATACTGATGAggagataatatttattggaGAAGAAGCTGTAATCGATGACCACAACGAGgaatttgatataataaagtGTCGTATTTGTGGACTATTTTTTGGTACTGCTAAGAGCTGTTACTTGCATGCAGAGATGCATAATACAGAAAATTACTATCCTTGCAGTATGTGcagtaaaattttaaccaatCAATCAGACAGCTTAAAACATAGTACACAACATGTAGCACCTAAACCTAAACAAAATCGAAGAAGAATACCGATGTACAACAAAGATGAATCCAATCAATGTAAAAACAACCTACCGTCGACTCCTATTGCGAATAAAGATAATGCTGGAGATAATAATATCCTTGGTAAAGAATTAGTCGCGAATAAAActtctgttgaaaataaagatgatCATGATATGATAAAATGCAGAATTTGCGGAAGGTATTTTGGGACTGCTAAAAGCTGCTATAAACATTCCCTCATTCATGCTTCAGAGGAATATATGCCGTGTAGTATgtgcgataaaatatttatgaatgcAACAGACAGCTCTAGCCATAGTCTGGAACATATACTACCGAACTTAAATCGAATAAGGGCAgcaggagagaagagaaaactgTTTAATAACATTCACAAATTTCTGCCAGTTAATAGAagcagaaaaattttgaataacgaGAAACCTAATGATCATGTTCAGTCTATTGTAAAAACAGTCAAGGATCAAGCTTCTATTGACCAAAACAACGACAGTAGTATGATAAGATGTAGATTTTGTGGATGCACTTTTCCTGATGCTAAAAGCTGCTATACACATGCAAGTATTCATGTTAGGGAAGATTACTACCCCTGCACTATGTGTGATAAAACATTTACAGTTGCAAAAGACTCGTGGAGACATAATCTGGACCATATATTGgttgaagagaagaaaaaaaaattgtctgcaAACGTATGCGACATATGTGGAAAGAGATACGTGTCGGAAGCTAGATTAAAGTTTCATCAAACTTGTCATAATCCAAAGAAGAAAGCATGCTATTGCGAAAAATGTGATAAAGTACTGGCTTCAGAGACATCGCTGTTTTATCATATGGACAATGTGCACAAAAAGTACGCAAAAGAATATGGTTGCGAAGTATGCGAAAAACGTTTTAGaaatcaaTCGGACTtcaattctcatcaaataaaatacaatcatCCAAATTTCGAATGCACTTTATGCGGTGAAAGATTTTACGCTCCTGATAAACTGATATTGCACAAAGAAATTGAAGATAATGATAGGTACCAAGACATTATCAACAAATCAGAGAATATTTCATTAGATTTATTGCccaataaatcgaaaaaaagataTCAGGAGGTCTATCTAAATTTCACTGACtggaagaaatcaaaaaacataaCCTCAACACGTGAACCCGTGTTGTTGCTATATTTCAAGGAGCTATCTATAGTACGAAAAATGGTACCATCAACCTTGTGGTCTCTATATTCCATATTGAAGAAAACTTTATATCTCTATGAGAATGTtgacatttcaaaatttgaaaaattaagcagctttttgaaggaaaaaaacaaaggttACCGGcccaaaaaatcaaagatttttacaACAGCTGAAATTTCAAGATATTGTAACGAAGCTTcggattttcaatatttagcAAATaagGTTATTCTGATTGTCGGATTCAGTGGCGGTCtcaaaagagaagaaatttaTAACATCTCCACCGATGACGTAAAAAATGATGGAAATAATTTGATCTTCAGTATTCCGAAGAGCAAAAATACTGTTCAAAAATCGTTCATCATTATCGGAAAGTTGTGCGATtacgtaaaaaaatatcaatcacTTCATacaggaaaattaaaaaatttctttatcaacTATCAAAAGGGAAAATGCACGAATCAAGTAATTGGGATACACAAAATTGGATCGATACCTAGACAAGttgcagaatttttgaagTTACCTGAACCAGAATTATATACTGGTCACAGTTTTCGCCGTAGTTTTGCAACATTACTCGTTGATGCCGAAGCTAATGTAACAGAGCTCAAGCGTTTTGTTGGATTGGAGTCATTGTCAACCGAGGAATTAATCCCGATACCAATTAAAGAGGAAGATACTAATAGCATGGACTTGGATCAGAAAATTTTGACTCATTCATCTGAAACAGGAATCAAAGAATTTCAGGCACCAAGAATTAAAACCGAGATAGAATTTTCCTCCCAGTCTTCTCTTctaaatgaagaaattataaagaCAGACCCTGAGCTGCTAGAGGAGTTTTATGCGGCACCAGAGAGGATAAAATTGGAGGATGAACAAATTTCGGAAGAATCTAAAACCATTGATATAAAACCAAccatattatatgaaaatgatgaagatCAGAGCTTGAAGATTTCTGAAGTTATGTTAAAAGAAACTAATTATGTAACTCCACTTCTGCTCTGCAGACTTTGTGCGTATCAGCGAAATGATACTGTTTATATGTTTGGCCAGAACGAAACGTAcagaaatattatagaaaaaattgaacactGCTTACCTATTGTGGTGAGGGAGACTGATACTCTACCAAAACAGGCTTGTCATTCGTGCTTAGAGAAGTTAGAATTTTgtcatcaattttataaaagtgTACAAAAGGCTGAAGAGCAGCTTGTTACGTTGGGTAGAAAAATATCGGACGAATTTTGGGAAACAGACAAACATTATCAGACTGCTCTGCTACACAATGAACAATGCGGTTCTAAGAAACATGAAATAGAATTAGATACACCTTCCGCTGAGGacacaaataataatcagtCTACATCTATGTCTGAAAAACCTCAAATAGCAAATCCAATCGCAGTAAGCAGTTCATCAAATGCAATGCTTTACTCGGAGGAATTATTTCCTAGTAATATAAACACTTTGAGTTCAATTACTCAGAATAGGAACATAGATTCTTCAAGTTTTGAACACACATCAATGTCAACATCCCTAGTTGAAAAGAATTTACCACATTTGAATGGAGTACCAAGACTTGATGAAGCAGTGTCTACTTCCAAACTGTATTCTCCTGCGATTacaatgaattataaattttctaataacgTTAGAACAAAAAGCCAAGATAGAGCCAATGAAACTTCTGCTAACTATAGTCTTCTTGGAAAGATGATAAGATGTCGGATTTGCGGAAAGCTTTTTCGAACTGTTATAAAATGTGATTTACATTCAAAAGTACATGCATTGGAAAATTACTACCCCTGTAGTCTCTGTGATAAAACTTTCACAATTTTGGAAGACTGGCATGAACATCGTCTTGACCATATACGGAATGAAAAGTTTAGAAGAAAATTAGCAACTTTTATCTGTAATGTATGTGGTAAGAAGTTTTTATCAGAGGCGAGACTACAGTTTCACAAATTTAATCACAGCTCTGACATCAAACCATCGTACTGCgaaaaatgtgataaaattatGGATTCAGAGGCAGCTCTGAAACAGCATGTACTGACTATACATTCACAAGATAAGGATTACTGCTGTGATATATGTGGAAAGAaattcagAAGTGAATCACAGCTCAATGGTCATAAAGGAAAACACACCGAGAAACGAATTAAAGAGAACTTTTCATGCGCCCATTGTGAAAAGTCTTTCGAGCAGAAATGGAGTCTAGTTATTCACATACGAAGTCACACAGGAGAGCGACCATTCAGCTGTGACTTTTGCGATAAGTCTTACATGACCAAAGCGCAAAGAAATAGTCATCGGAGAACTCACACAGGCGAAAAACCTTTCACATGTTCAACATGTGGAAAAACGTTTGCCCAAGCGTTAAGGCTAAGCGAACATGCTAATGTTCACGCACTAACTAGGCCTTATAAATGTTCTCTTTGCGATAAATCGTTTAAAAGAATACACGCAAGAACTATTCACATGACTACTCATACGGGTGAAAAACTATATCAGTGCGATAtctgcgaaaaaaaattcaggtggCCTACGGCCATACGGAGacacaaaaaatatcaacactGA
Protein Sequence: MAKRKLRLEIQQSDEHGECGGPKVPRWYGQHSITTKDITEKNQQSINSENYVREISNSDLQHVKQELKEHVEPATESTISFKDVVKVTSEGYKLETLEPDVEEELHTEIEETRSENRNLAGKFETVYIDSAMLCENDEPPKSGQSSEISGSIFQSTNDTTLLCRLCATQRKDMIYIFERNEAYKNIIKKIQDCLPILVTKTDTFPKQVCRLCLEKLEMFHKFHKTVIEAEKQFNNLGEKMSEALKNTDKNVQTSLPQNEQMDSKKHSKKLVSDKKLCSLPLTFKSPEILNNPKESVNKTNTDEEIIFIGEEAVIDDHNEEFDIIKCRICGLFFGTAKSCYLHAEMHNTENYYPCSMCSKILTNQSDSLKHSTQHVAPKPKQNRRRIPMYNKDESNQCKNNLPSTPIANKDNAGDNNILGKELVANKTSVENKDDHDMIKCRICGRYFGTAKSCYKHSLIHASEEYMPCSMCDKIFMNATDSSSHSLEHILPNLNRIRAAGEKRKLFNNIHKFLPVNRSRKILNNEKPNDHVQSIVKTVKDQASIDQNNDSSMIRCRFCGCTFPDAKSCYTHASIHVREDYYPCTMCDKTFTVAKDSWRHNLDHILVEEKKKKLSANVCDICGKRYVSEARLKFHQTCHNPKKKACYCEKCDKVLASETSLFYHMDNVHKKYAKEYGCEVCEKRFRNQSDFNSHQIKYNHPNFECTLCGERFYAPDKLILHKEIEDNDRYQDIINKSENISLDLLPNKSKKRYQEVYLNFTDWKKSKNITSTREPVLLLYFKELSIVRKMVPSTLWSLYSILKKTLYLYENVDISKFEKLSSFLKEKNKGYRPKKSKIFTTAEISRYCNEASDFQYLANKVILIVGFSGGLKREEIYNISTDDVKNDGNNLIFSIPKSKNTVQKSFIIIGKLCDYVKKYQSLHTGKLKNFFINYQKGKCTNQVIGIHKIGSIPRQVAEFLKLPEPELYTGHSFRRSFATLLVDAEANVTELKRFVGLESLSTEELIPIPIKEEDTNSMDLDQKILTHSSETGIKEFQAPRIKTEIEFSSQSSLLNEEIIKTDPELLEEFYAAPERIKLEDEQISEESKTIDIKPTILYENDEDQSLKISEVMLKETNYVTPLLLCRLCAYQRNDTVYMFGQNETYRNIIEKIEHCLPIVVRETDTLPKQACHSCLEKLEFCHQFYKSVQKAEEQLVTLGRKISDEFWETDKHYQTALLHNEQCGSKKHEIELDTPSAEDTNNNQSTSMSEKPQIANPIAVSSSSNAMLYSEELFPSNINTLSSITQNRNIDSSSFEHTSMSTSLVEKNLPHLNGVPRLDEAVSTSKLYSPAITMNYKFSNNVRTKSQDRANETSANYSLLGKMIRCRICGKLFRTVIKCDLHSKVHALENYYPCSLCDKTFTILEDWHEHRLDHIRNEKFRRKLATFICNVCGKKFLSEARLQFHKFNHSSDIKPSYCEKCDKIMDSEAALKQHVLTIHSQDKDYCCDICGKKFRSESQLNGHKGKHTEKRIKENFSCAHCEKSFEQKWSLVIHIRSHTGERPFSCDFCDKSYMTKAQRNSHRRTHTGEKPFTCSTCGKTFAQALRLSEHANVHALTRPYKCSLCDKSFKRIHARTIHMTTHTGEKLYQCDICEKKFRWPTAIRRHKKYQH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -