Basic Information

Gene Symbol
-
Assembly
GCA_963924015.1
Location
OZ001263.1:13403857-13407138[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 7.7e-05 0.008 17.2 1.3 1 23 328 350 328 350 0.98
2 14 9e-05 0.0094 17.0 1.6 1 23 356 378 356 378 0.97
3 14 5.5e-07 5.7e-05 24.0 2.0 1 23 384 406 384 406 0.99
4 14 0.55 57 5.1 0.1 1 12 417 428 417 437 0.86
5 14 1.6 1.7e+02 3.6 5.7 1 20 461 480 461 483 0.91
6 14 0.036 3.8 8.8 0.1 1 23 489 511 489 511 0.93
7 14 0.021 2.2 9.6 1.8 1 21 530 550 530 551 0.94
8 14 0.0011 0.11 13.6 0.1 2 21 559 578 558 579 0.93
9 14 0.086 8.9 7.6 0.7 3 23 588 608 587 608 0.98
10 14 6.9e-07 7.1e-05 23.7 3.5 1 23 618 640 618 640 0.98
11 14 0.0061 0.64 11.2 1.3 1 23 646 668 646 668 0.98
12 14 7.6e-05 0.0079 17.2 1.6 1 23 674 696 674 696 0.98
13 14 0.0012 0.13 13.4 0.8 1 23 702 724 702 724 0.97
14 14 1.9e-05 0.002 19.1 3.6 1 23 730 753 730 753 0.98

Sequence Information

Coding Sequence
ATGAAAATACTGATAAAAGATTCAACAGGGGATTTAATCCCTATATCAATAAAAGATGAAGATACTTTCaacgatttaaataaaagaatggaaaaagaatACGGAATGCATCtgaattttgacaatttaCAAAATGATAATAGCATGGACTTGATGGATCAGAATATATTGACATATTTTTCTGacAATAATCATCAAGCTGTAGTTGattcagaaaattattcacaaaAGTCTGAATTATCTAAACAAAGAGGAAAGGAATCCGTCGACAAAATGCAAATAGAAACAACAGCCGCAGAGTGTGATCCAATATCGATTGAAGATATTGTACAAATAATACCAGAGGGATATCATTTAGTTACGTTGAATCCTGAACTAGAAGAAGAATTTTGTGAAGGAATTGGGGAAATGAGATCCGAAGAGACAGAAATAGCTGAAAAAGTGGAAACCACTGATATTAGACTTGCTTTAGTATCCGAAAATCACGATGTTCAGAGATCGGATAAGATTTTTAAAGATTCTAAATCTGTATTCGGATTGAATGATGATATAACTAGCTCCCCATTAGTGTGCAGACTTTGTGCAACTCGAGGAAAGGACATGGTTTATATGTtcggaaataataaaacttacaataatattataggaATGATTGAGCAGTGTCTAACTATAGTGGTAAAGAAGTCTGATAATCTACCAAAACAAGCCTGCCGTTCGTGCCTAGAAAGACTTGAGTTGTGTTATCAGTTTCATAAGACTGTAACAGAGGCCGAAAAGCAGCTCCTTATGTTAagcggaaaaatatttcaccagactaagaagaaagaaaaattgcagCTGTGTGGTAGACAACAGGATACTATTATCAATGAAGAATTACAGAGCATAGATACAACTGAAGAAAATGTCATTGAATCATCTGATTtagaaagaatattaaaatctcAACATATGCTTACTGTACATAGACAGTACAAGGAATACTGTTGCGATATTTGTGGAAATcagtttagAGCTCAAGCCCAACTGTCTGCCCATCAAAGAAAACACAAAGACGAACGCCCATTTGAATGCGAAATTTGCAATAAAACATTTTACTCCAACGATATACTAAGGCGTCATAAAAAGCTGCATCTACCTGACAAACCTTATCAGTGTGATCAATGCGGTAAACGATTCGACAGAAACAATACTTTGACAAAACATTTGTTGAGACATCAAGTGGAAGCTGGTCAATCTATGATATGTCACATCTGCAATATTTGCAAAGAAGTATTTGCGAATACTGTAATTGCAAAGACACATTTAAAGGATTGTGCAATGATTACCAAAGACAATAatcaagataataaaatagtagaattgaatttgaagGAAACATATAGATGCGAATACTGCGAAAGATGCTAtacagaaattgaatttatgaaaaatcacAGATTATGTCATAGCAAACCGTCCCCGTACATATGCACAGTATGTGACACAGCTTACGCAACTTATAATCAAGCCACGGCGCATAAAACGGCGCATAAAAAGTCCCGTAAAATCACAAGTGTTAAAGACGAACTATTAATTCCGAAATATTTCGTCTGTGAATACTGTGACAAACAGTTCCTTCATTTCACTAACATGAATATTCACAGACGGTCATGTTCAAACGGAAAAATTTGGACTTGTAGATACTGCGGAGCTGTCTTTGAAAATGCTAGAGAACTCTCAAGGCATAAGAAGGGAGAACTTAACGAGGAAACTTGGCTTTGTAATGAGTGCAATAACAGTTATGGCTCTGAATGTGCCCTAGAAATACACAGAGATACTCATTCCACTTTActgagagataaaaaaaacttttcgtgTTTACATTgcggaaaaatattcaaccagAAGGCGCATCTCACTGTTCATATACGTAGTCACACAGGGGAGAGACCTTACAATTGTGACTTATGCGATAAAGCGTATAAGATAAAAACTGAGAGAGATAATCACCGCAGAACTCACTCTGGTGAGAAACCATTTAAATGTTCAATATGCGAAAAGACGTTTGCCAATACAGCTAGACTCAGAGAACACACAAGATTTCATTCGGGAAAAAGACCTTACAATTGTTCCCTCTGTAATCAATCCTTCAAGAAAGCAAACGCAAGAAATGTTCACATGACTATACACACTGGGGAAAAACCCTACCAGTGCGACGTTTGTGGAACTCATTTCAGACGTACCGGTGATATGCGAAAACATAAGAGAACTCAACACGGACAGAAATTGGAGACTAAAAATGAGACGAACTTTGAAATTCATTCTAAAATATATGATACtttgtaa
Protein Sequence
MKILIKDSTGDLIPISIKDEDTFNDLNKRMEKEYGMHLNFDNLQNDNSMDLMDQNILTYFSDNNHQAVVDSENYSQKSELSKQRGKESVDKMQIETTAAECDPISIEDIVQIIPEGYHLVTLNPELEEEFCEGIGEMRSEETEIAEKVETTDIRLALVSENHDVQRSDKIFKDSKSVFGLNDDITSSPLVCRLCATRGKDMVYMFGNNKTYNNIIGMIEQCLTIVVKKSDNLPKQACRSCLERLELCYQFHKTVTEAEKQLLMLSGKIFHQTKKKEKLQLCGRQQDTIINEELQSIDTTEENVIESSDLERILKSQHMLTVHRQYKEYCCDICGNQFRAQAQLSAHQRKHKDERPFECEICNKTFYSNDILRRHKKLHLPDKPYQCDQCGKRFDRNNTLTKHLLRHQVEAGQSMICHICNICKEVFANTVIAKTHLKDCAMITKDNNQDNKIVELNLKETYRCEYCERCYTEIEFMKNHRLCHSKPSPYICTVCDTAYATYNQATAHKTAHKKSRKITSVKDELLIPKYFVCEYCDKQFLHFTNMNIHRRSCSNGKIWTCRYCGAVFENARELSRHKKGELNEETWLCNECNNSYGSECALEIHRDTHSTLLRDKKNFSCLHCGKIFNQKAHLTVHIRSHTGERPYNCDLCDKAYKIKTERDNHRRTHSGEKPFKCSICEKTFANTARLREHTRFHSGKRPYNCSLCNQSFKKANARNVHMTIHTGEKPYQCDVCGTHFRRTGDMRKHKRTQHGQKLETKNETNFEIHSKIYDTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-