Basic Information

Insect: Macrophya annulata
Gene Symbol: -
Assembly: GCA_963924015.1
Location: OZ001257.1:7181115-7183747[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0007 0.073 14.2 5.9 1 23 279 302 279 302 0.95

2 10 2.6 2.7e+02 3.0 1.3 1 9 317 325 317 339 0.80

3 10 2.8e-07 3e-05 24.9 0.9 1 23 345 367 345 367 0.98

4 10 4.9e-05 0.0051 17.8 0.9 1 21 374 394 374 395 0.94

5 10 5.3e-05 0.0055 17.7 0.5 1 23 435 458 435 458 0.92

6 10 2.2e-06 0.00023 22.1 8.0 1 23 482 504 482 504 0.98

7 10 6e-05 0.0063 17.6 2.5 1 23 510 533 510 533 0.94

8 10 0.0094 0.98 10.6 3.1 1 19 555 573 555 577 0.91

9 10 9.8e-06 0.001 20.0 0.2 1 23 583 605 583 605 0.99

10 10 3.9e-07 4e-05 24.4 1.4 1 23 611 634 611 634 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0007	0.073	14.2	5.9	1	23	279	302	279	302	0.95
2	10	2.6	2.7e+02	3.0	1.3	1	9	317	325	317	339	0.80
3	10	2.8e-07	3e-05	24.9	0.9	1	23	345	367	345	367	0.98
4	10	4.9e-05	0.0051	17.8	0.9	1	21	374	394	374	395	0.94
5	10	5.3e-05	0.0055	17.7	0.5	1	23	435	458	435	458	0.92
6	10	2.2e-06	0.00023	22.1	8.0	1	23	482	504	482	504	0.98
7	10	6e-05	0.0063	17.6	2.5	1	23	510	533	510	533	0.94
8	10	0.0094	0.98	10.6	3.1	1	19	555	573	555	577	0.91
9	10	9.8e-06	0.001	20.0	0.2	1	23	583	605	583	605	0.99
10	10	3.9e-07	4e-05	24.4	1.4	1	23	611	634	611	634	0.97

Sequence Information

Coding Sequence: ATGGATAattggaaatttattaaagaagAACCGGAAGACAATGAATCCCATGAAGCCAGGTGTGATTACTTTGAGATTTCTGAATCCTACTCACCATTTAAATCCGAGCTACTATGTGATGTCAAAACTGAAAATGGAGAAGAATTTTACTCTACATTTGAACCTGAGCAATTGTGTGATACCGAAGTTGAAAGTAaggaagaatttttcgaaaaagaagagaacaaTAATCAAGATGCAGGAAAAACTACCTCATCTTATTATCCTGAATTGTCAATTCCATTAGTACGAATTGAATACTCACAAAATCAGGAAATCATGAAATACCTAAAACCTCCACAATCTGAAGTCACATCATCCACCAGTCTGCATTTAGAAAACGAAACGATAAAActAAATCTGAACTTGAAAGCTGAATCTGTGGAACTTGAAACATTGACCGAAAATACACTTGGTCAATCTTCTGAAAATTATCACTATGCTTCACCATGGGACTTTGTTTCGGTTTCAAATTCATATGATCAAAATAGCTTAAAGAAAAATGCCATGAAGACGGAATTTGATGATAACAATCTGTctaataaagtaataaaaaaagaatacgaaGACGAAACTTTCAGAGAATTATTTACAAACAAATCTACCTTGCCCAGGGGTGtttcgaaaaagaaatttattcaaaagacTCTCAACTTTAAAGTAGTAGAAAAGCAAAGGAAAGATGAAAATACAAATCCTAAATCAACGCTGCAATCGTATAACTGTGATTCTCCTAAGCATATCAGCAAGCTTCAGCCTCGATATTCCGATTCTAATTCTCATCCAGATAAATCATTCTTCTGTAAATTATGTAACATGTATTTTGCGAGAAAATCAAACCTTAAGCAACACAGATGTAATCAACATAGTAATGAAGACCTAGGACCGCCAagatttgataagaaaatattttcatgtaaAGTTTGTGGTAAACCTGATACACAGATATCCGAATCACGTCGACATTGCGAAACTCACACAGCAATAAAACGATTCGAATGTGATATATGTGAGAAAACATTCAAGagaaaagcatatttacgcGATCATATACTTAGACATATAAATTCGGATCAGCAATACTTCTGCAATAATTGTTCAAGAGTTTATAAACGTAAGGCAACCTTACGGAGACATATTACGATGTTCTATGCAGAAGATACGACAATTATGAAATGCAATCCACAATCTCACGTCCCTCAGTTAGGATCAAAAAGtaatcacaataataataaaataactattgAAGCACCGTTGATGTTGTACAAATGTCATGTTTGTGGCCAAGGTTTTGAAGACAAATCAAGCATGGAAGTACACGttgaatttttacatattGAAATATCTGAGAAGTATGCAACCAAGAACCAACCTCGACCTCCTAACTCATCATTGGACAAACCTTATCAATGTCATACTTGcaaaaaaagttatacgcAGTCGTCACATTTAAAAAGGCATCAGGAATCTCATTTGTCAAATAAATCTCATATCTGTGGATTGTGCAACCAGACTTTCACAACAACATCGAGCCTAACACGACACTTGCTTAATAAACATAACGAGATACGATCGATAAGGACAAAAAAATCTCTtgaaaaaaagcagaaaactCCAAAGAACTTTAGGTGCAAAATTTGTGATCATGTCTCAACAAGTTTCAGCGATTTACTTCGTCATTGCGCGATTCACGATGCAAGAAAACCGTATGAATGCGACATATGTAAAAAACAATTCGCAGTAAAGGGATATTTATACGCACATATACTAACACATGATAATTGGAAACCATACCCTTGCaataaatgttcaaaaatttacagGCGCAAGTCTAGCCTACAGAGACATATTAATATCAGCCATTctggaaagaggaaaaaacaTAATGTAGAATTTGCCTAA
Protein Sequence: MDNWKFIKEEPEDNESHEARCDYFEISESYSPFKSELLCDVKTENGEEFYSTFEPEQLCDTEVESKEEFFEKEENNNQDAGKTTSSYYPELSIPLVRIEYSQNQEIMKYLKPPQSEVTSSTSLHLENETIKLNLNLKAESVELETLTENTLGQSSENYHYASPWDFVSVSNSYDQNSLKKNAMKTEFDDNNLSNKVIKKEYEDETFRELFTNKSTLPRGVSKKKFIQKTLNFKVVEKQRKDENTNPKSTLQSYNCDSPKHISKLQPRYSDSNSHPDKSFFCKLCNMYFARKSNLKQHRCNQHSNEDLGPPRFDKKIFSCKVCGKPDTQISESRRHCETHTAIKRFECDICEKTFKRKAYLRDHILRHINSDQQYFCNNCSRVYKRKATLRRHITMFYAEDTTIMKCNPQSHVPQLGSKSNHNNNKITIEAPLMLYKCHVCGQGFEDKSSMEVHVEFLHIEISEKYATKNQPRPPNSSLDKPYQCHTCKKSYTQSSHLKRHQESHLSNKSHICGLCNQTFTTTSSLTRHLLNKHNEIRSIRTKKSLEKKQKTPKNFRCKICDHVSTSFSDLLRHCAIHDARKPYECDICKKQFAVKGYLYAHILTHDNWKPYPCNKCSKIYRRKSSLQRHINISHSGKRKKHNVEFA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00938975;
90% Identity: -
80% Identity: -