Basic Information

Insect: Macrophya alboannulata
Gene Symbol: Glis3
Assembly: GCA_949628255.1
Location: OX451207.1:8537885-8542660[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.0014 0.17 13.3 0.1 1 23 315 340 315 340 0.97

2 5 0.47 59 5.3 0.1 5 23 382 402 376 402 0.80

3 5 1.5e-06 0.0002 22.5 0.6 2 23 409 432 408 432 0.97

4 5 0.00011 0.014 16.7 2.3 1 23 438 462 438 462 0.96

5 5 3.9e-06 0.0005 21.2 0.3 1 23 468 492 468 492 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.0014	0.17	13.3	0.1	1	23	315	340	315	340	0.97
2	5	0.47	59	5.3	0.1	5	23	382	402	376	402	0.80
3	5	1.5e-06	0.0002	22.5	0.6	2	23	409	432	408	432	0.97
4	5	0.00011	0.014	16.7	2.3	1	23	438	462	438	462	0.96
5	5	3.9e-06	0.0005	21.2	0.3	1	23	468	492	468	492	0.95

Sequence Information

Coding Sequence: ATGCACCTTGAGAAGTTCGCTAGCACCGCTGACGAGGAGCACCGTCGCGCACTCGGAAACGGTATTCAGGATGAATTTCAACGCTCCAACGGTTCGGTCACAAGTCAAACTTGCTGGGGATCCTCGGTCAGCGAGGCGAGCAGTTTATCCCCGTTGTTATTGAGCCCTCGGGACTCTGCTGACTGGGACCAGTACGGGGCGACCCTTCAATACACCTGTTTTCCGTACCCTCCAACCCCCACGGCTCCCCCGCGACCGGACAGTGCCGCGGACACAATCCCCGCATGGTGTAACCTCTACGGAGAGTCCGATGACGCGACAACTGATACCGCGCCGTCGACACCACGTCACAAACTGCCCTCAATGGGGACCGCGTTCTCCAGATCATTTTATCCGGCGGCAACTACCACCACTACCACAAGTTACGCTAATTACCACGGTACTGGTTCACAGTTGTTCGACAGTCAGCAACAGAACGTTGTTAATATTGTGGCTGATGAGTTTGATCTGAGTTTAATTCGTGGTGACCCTACTTCCCTTCTTGGTGGCAACGGATCGCCACCCTGCCCAACACCTTATCTGGACGAACTTCAGGAGGAGCTGGACCCGTTCGCCGGTTTTAGTAATTCTTGTTACGCGGTTGGACACCTTGTGTCGTCACCGCCAACCCCGTTGTCGCATGGCTCGTCGACGTCGACCACCTCGTATTACCATAATCGAGGACATATTGGAAACGGAACGTCAGCGAGCAGCTGTCTTTTGGACGAAACGATCCTCGAGAATAGCAACCAGATTGTTCTGCCCCAGGACGAAGGACTTCTTCTTGCAAATGACCGCGAGTGCACGTTCACATCATCGTCTCCGACGATTGTGGATAGTGTCAAACTAGAGGCTCCTCCTATCGGCTGCTCCCTGATAGACGATCCATCATTCGGGCTGACCTATCAGTGTCGTTGGATGGACTGCGGTTCCGCTTTTCCAGAACAGGCCAGTTTAGTCCGACACATAGAGAGGCGGCACGTTGAATCCTCCGCATCTGGAGCTCATAGCCATACCAAAAGAATGCAGCGAGATTCTAATTCCGGGGAGACCGGTACAGTCGTCTCTAATACTCCTCAGGACGAATTCGCCTGTCTTTGGGAAGGCTGTCCACGTGCTCGACCTTTCAATGCTAGATACAAGCTCCTGATACACATGCGCGTACACAGCGGTGAAAAACCGAACAAGTGTCCGTTCGCAGGCTGTAAAAAGGCGTTCTCCAGGCTAGAGAACTTGAAGATTCATCAAAGATCGCACACAGGTGAAAGACCATACGCCTGCCAGCACAGAGGCTGTTCGAAAGCCTTCAGCAATAGCAGTGACCGTGCAAAACACCAAAGAACACATTACGATACGAAGCCATACGCATGTCAGGTGAGCGGATGTGGAAAGCGCTACACGGATCCGTCTAGTCTTCGTAAGCATGTAAAAAATCACGCAGAGCCTAGCCCAGGGTCGTCTGGTGCCGGAGGCAGAGGATCGACCGGTGGTTCATCGTGCAAAACTTCTTCAACACGTATCAACGCTAATACATCGACCCAGAGGATTCAGCAAAAAGCATCTTTGAATGAAACAGAAGCGGCCCTACCCGGAACAATGTTTCGCACGAGGGTGCCTTCCGACCTTGATCTAGGGAACCAGTACGAAGACGAAGACCTTCTGCTCTCTACTGTATGCGGCGAGGAGCGTGTTACAACGCCTTTGGACGAAAGCCATAACGAGTACATTCCCTTTGAGTCTGTGCGCCGATTCCTCATCGGAGACGCAAGCCATGTCGAAGTTACCGATGCCACCGTTTATACAGAAGGTGACGTTACGGATTTTCAAGAACTCGGATCCGACATTGAACAACAATTTCTGGAGCTGAGTAATTTGGATGATTCGGTATTCATCGGGGGATAA
Protein Sequence: MHLEKFASTADEEHRRALGNGIQDEFQRSNGSVTSQTCWGSSVSEASSLSPLLLSPRDSADWDQYGATLQYTCFPYPPTPTAPPRPDSAADTIPAWCNLYGESDDATTDTAPSTPRHKLPSMGTAFSRSFYPAATTTTTTSYANYHGTGSQLFDSQQQNVVNIVADEFDLSLIRGDPTSLLGGNGSPPCPTPYLDELQEELDPFAGFSNSCYAVGHLVSSPPTPLSHGSSTSTTSYYHNRGHIGNGTSASSCLLDETILENSNQIVLPQDEGLLLANDRECTFTSSSPTIVDSVKLEAPPIGCSLIDDPSFGLTYQCRWMDCGSAFPEQASLVRHIERRHVESSASGAHSHTKRMQRDSNSGETGTVVSNTPQDEFACLWEGCPRARPFNARYKLLIHMRVHSGEKPNKCPFAGCKKAFSRLENLKIHQRSHTGERPYACQHRGCSKAFSNSSDRAKHQRTHYDTKPYACQVSGCGKRYTDPSSLRKHVKNHAEPSPGSSGAGGRGSTGGSSCKTSSTRINANTSTQRIQQKASLNETEAALPGTMFRTRVPSDLDLGNQYEDEDLLLSTVCGEERVTTPLDESHNEYIPFESVRRFLIGDASHVEVTDATVYTEGDVTDFQELGSDIEQQFLELSNLDDSVFIGG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01412648;
90% Identity: iTF_01411862;
80% Identity: -