Malb027632.1
Basic Information
- Insect
- Macrophya alboannulata
- Gene Symbol
- -
- Assembly
- GCA_949628255.1
- Location
- OX451212.1:16131169-16133497[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 2.3 2.9e+02 3.1 0.6 1 11 256 266 256 270 0.84 2 10 0.01 1.3 10.5 0.2 2 23 278 299 277 299 0.97 3 10 0.014 1.8 10.1 2.5 1 23 300 322 300 322 0.98 4 10 0.012 1.5 10.3 0.8 1 23 331 354 331 354 0.91 5 10 0.008 1 10.8 1.1 1 23 375 397 375 397 0.96 6 10 6.7e-05 0.0084 17.4 2.3 1 23 403 425 403 425 0.96 7 10 5.1e-06 0.00064 20.9 0.5 1 23 431 453 431 453 0.99 8 10 4.3e-06 0.00054 21.1 2.3 1 23 461 483 461 483 0.98 9 10 0.00015 0.018 16.3 5.6 1 23 488 510 488 510 0.98 10 10 0.00066 0.083 14.3 2.5 1 23 530 552 530 552 0.98
Sequence Information
- Coding Sequence
- atgctTAAATGCAACGCACCGGGATGTACGACggacgaaaattcaaaaataaacgGGGAGAGTATCACTCTGTTCTCTTTCCCAACCTACGACGAGTCGCTGGTTAAAAAATGggaagaaaattcaaatctcgGATCAGAATCCTTAGATAAAAATAACGGGGAATTAAAATTGTGCCAGTTGCATTTCGAACCCAACAGCTTTGCCTCGGACGATAAGAACGCGTTGGCTCCTGGCGCTATGCCGACGATatttgAATTTGATAGCAAAAGGAGAATCAAGGAGGATGAAGAGCCGGATGAACCCCAAGAAGAACCGCCTTCCAAACATAGAAAATCacaagaagatgaagaagagtCAAAAGATGTTACAAAACCTCAGCAAACTGATTATTTGACTAAAATTAAAGCAGAATCAGATGAAGATATTAAGCCCGGTGAAAATATGCCGTTGAGTATAATAGAGAAGGTACAGAAcagtttgaataataaaaacggaGGAACATCGTCGTCTTCTGTATTCACAAAACAGATAGACATGGGAAAGAAGGTGTATCGTTTGATAATAAGAATCGATAAAGTGATTGAAAAACGAGATTATACAAAAGAGATAACGACAAAAGTTGTTGAAAAAGAACAAGAGGATACAAAACCGAAGAAGACCGTGTCCAGTATCGGTATTGGTTCGAAAAATGGAGGAGTTATAAGACCGTGTTCAAAAACTGGTTGCAAACTTGTTAAAACAACCCTGAATTCGAAGCCTGTATTCCAATGCGAACGTTGCAACAAATATTACATTGTTAAGGAGAGTAAAAGCGACGTGAAAGACTGGACATGTTACATATGTCAAGAAGTATTGTCGAGTCCGGATTCCCTCAGTTTTCATATCCGTAAACATTTCACGTGCGATATGTGCCAGGCGCAATGCAGCACGCaaatatcgtacgacaaacaTCTTAGGCTTCACGTTAGCACCGATCCATTGCTTCCATACAAATGCCACAAATGTCCGAATATATTTGAGGTGAAGGCTGACGTGAGACAACATTACGCGGATAATCATACGAAGATAACTAAACAGGATCGCGTCAATACCAAGAAGCAATCTTCTAAACAGATTCTCTTCAGATGCCAGTATTGTTACGCGGTATTCAAAAAGGAACAGGCCTACAAAAGTCACGTTGAATTGCACATGGGAAACGGTGAATTTGACTGCGCTTTATGCACCAAGAGGTTTAAGACTGCCAAACATTTGGCTACACATCAGGCCAGACATTTGGGAACTCTTAAATATACTTGCAGAATTTGTAGCAAGGAATTTTCCAGCTTAGACGCTGTTGAAAATCACATGAAAACTCATATGGAAGTTGTGAGGGAAGAACACAAGTGCAATATTTGCAAAAAGATATTTAAAAGCGAGTCTGTTCTTAACAGTCATATGAGAGGACACCTATCGCGAGCACACAGATGCCCGTCGTGCCATAAAGCATTCATTAATAAAACCACACTAAGGATACATTTCAAGACTCATAGCAAAGAGGCTACATCAAATCATTCGGGCAACAGAGATTcgaatctgaagaaaaaacacaCGTGCACATTGTGCCCGAGTACGTTTGACAGTCGTTCACGATTGTACAATCACATAATGACACACCTTGAGCAAATGCACGGTAACGAAGGCGGCGATGTTGTCTTTGACGGACTTAACGAACTCCTTGAAACCGACGAGGATGTACTTTCGTAA
- Protein Sequence
- MLKCNAPGCTTDENSKINGESITLFSFPTYDESLVKKWEENSNLGSESLDKNNGELKLCQLHFEPNSFASDDKNALAPGAMPTIFEFDSKRRIKEDEEPDEPQEEPPSKHRKSQEDEEESKDVTKPQQTDYLTKIKAESDEDIKPGENMPLSIIEKVQNSLNNKNGGTSSSSVFTKQIDMGKKVYRLIIRIDKVIEKRDYTKEITTKVVEKEQEDTKPKKTVSSIGIGSKNGGVIRPCSKTGCKLVKTTLNSKPVFQCERCNKYYIVKESKSDVKDWTCYICQEVLSSPDSLSFHIRKHFTCDMCQAQCSTQISYDKHLRLHVSTDPLLPYKCHKCPNIFEVKADVRQHYADNHTKITKQDRVNTKKQSSKQILFRCQYCYAVFKKEQAYKSHVELHMGNGEFDCALCTKRFKTAKHLATHQARHLGTLKYTCRICSKEFSSLDAVENHMKTHMEVVREEHKCNICKKIFKSESVLNSHMRGHLSRAHRCPSCHKAFINKTTLRIHFKTHSKEATSNHSGNRDSNLKKKHTCTLCPSTFDSRSRLYNHIMTHLEQMHGNEGGDVVFDGLNELLETDEDVLS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00938764; iTF_00939611; iTF_00939884;
- 90% Identity
- iTF_00938764;
- 80% Identity
- iTF_00938764;