Malb007205.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrophya alboannulata
Gene Symbol
ham
Assembly
GCA_949628255.1
Location
OX451207.1:6215069-6232141[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.026 3.3 9.2 0.3 2 23 263 285 262 285 0.93
2 9 1.1 1.4e+02 4.1 0.4 1 23 292 315 292 315 0.82
3 9 1e-08 1.3e-06 29.4 1.4 1 23 321 343 321 344 0.96
4 9 9.5e-07 0.00012 23.2 1.7 1 23 350 372 350 372 0.95
5 9 1.6e-05 0.002 19.3 4.9 1 23 378 400 378 400 0.99
6 9 0.0002 0.025 15.9 1.9 2 21 408 427 407 428 0.95
7 9 7.9e-09 1e-06 29.7 1.2 1 23 762 784 762 784 0.99
8 9 4.2e-07 5.2e-05 24.3 1.7 1 23 790 813 790 813 0.97
9 9 1.2e-05 0.0015 19.8 3.4 1 23 819 841 819 841 0.99

Sequence Information

Coding Sequence
ATGGGTGGCATCTGCTGCGCGTTAGACACGGGTCAAAGGGCACCACCGTCCATCACTTTATGTCATTACGCTTTCAGTTCCGGGGCAGAGTCAACTGGGTCAAGTACGAACCCGCCGACCAAAGCTCCGAAGATGGAAATGGAAGAAGTCTACCTTCCGTGGACGTTTTCCGGGTTTTTATCCGTTAACGAAACTCCCGTTTCAATTTGGTTCCGtgcaatttcatttaattGGAAAATATCACTACTCAAACTGTGTTACGGGCTCGTAGACTCCGTACCGCCTATATTCCTTATAAGATGGGTGAAGGCGGAAAGAGGAGTAAGGTGCGTTGTACACGGTCCATATGGAAGGAAGCTGCCGAGGGGTGACGACACGCAACAAACACCCTGGTTCAACGCGGTTAACGTTAAATTAGATTTTAAGGGCTACCGATTGTGGTCAGAAACAAAACTGAAGTCAATTCACATTCGAATTTCTGGAAGCGGCGTCCGAGGTTGGCTCGACGCGTCTCACGAAGCCAGCAATTGGCTCAAGTATGTCCGAAGTACGGAAAGTCCTCACGCAGTCAACATGCGTCACGTTCTCATTGGTGGacaggTCGTATACGAAACTATACGAGATATAGCCGCAGGTGAAGAGCTTCTCTTGGGCCACCGCGAACCATTACAGCTGCAGGATATGCTTGGGGAGAACACCGCGGAGGATCGAAGCGACAGGGAGACCGCTTCCCAACACAGTGGGACCGTCGACGAAGACAGAGAAGAGGACGAAGACGGCGATATCAGATGCACCGTCTGCGACAAGCCTTTCCAGGACATTGACTTACTTGACGGACATCTGGTGACTTGCCACAGGTATCCAGCTGAACAGTATCGGTGTGAGACGTGTCACAGAGGATACGCATGGAGGCCACTGGTTGTACGACACCGTTCGATCGTTCATGGAGACCTGAAGAAGTACCAGTGTGAAAACTGCACAAAGGTGTTCACTGATCCCTCAAATCTCCAGCGCCACATTAGGGCACATCACGTTGGCGCGAGAAGTCACGCCTGCCCAGACTGTGGGAAGACGTTCGCCACCAGTTCCGGCCTGAAACAGCACACCCACATCCACAGCAGCGTCAAGCCCTTCCAATGCGAGGTCTGCTTCAAGGCTTACACCCAGTTCTCCAATCTCTGCCGACACAGACGAATGCACGCTGATTGTCGTGCCCAGATAAAGTGCGGTAAATGCGGACAGTCCTGCAGCTCAGCATCGTCGCTAACGAAACATAAACGATTTTGTGACTCGACTGGACCACCTGGACCAACCGGAGCTATGCCTCAGCTTCCAGCTTCAGGACCAAATCCGTTCTTGGTGTATCCAAGACCTCCTGGATCGTTACCGGGATCCTTGCCATTCTACCCACCAAGTCTGATGGGTCCCTACCCTGGGATTTTTTCCACCACACAGAACTTCTTCAACAGCTCGCTTGTGTTCCCACCAAAAATGGAGGAGCCTGAAAAGCGGTGTGACAGCCCAAAGAAGGAGAGGTTCACGCCACCCCGTATTCCTACACACCACAACAAGGTCTCCCCATCCACAGCCGAGGAAGCAACTTCAACCTTTAGGCCATCTCCAGCTAGGCCTCCGGTTCAACCAACTCCAGAGAGTGACGAAGAGGCGCCATCGAAGCAACCGAAGCAGCCGGAGAAAAACGTCAAGGTTGAAGCAATGGAGGAATCGGCTGATCAGCCGCTTGACCTCAGGGTCGAGACCAGGAGACGCCAGACCCCCAGCGTTGCTGGAAGTCATAGTCCCTCCCCGGTACTTATGGTCGAAGAAACTCAAGCCGAACCGTGGAAAGTCAAGGATGAAGATCGCATGGAGACTGGGGTGAAAGAACTTGTCATCAGCCCGGTCTGCAGTGTTGCGGAACAACAACCACCGACGAACGCAACTCCTCATATGGCGTATCCACGACCAATTCGTCCGTCGTTCCTCGAGGCTATGTACTGCGCTCCATCCGGCACGTTTCCTGGTTTTCCAGGTGGCCCTCCACCGCCTTGTGGATCAGAGCCTCGGCTACTACCGCCACCACCACCTTTCGGACACATGCGTGGTAGCTTTCCTTTTTTAGCACCGCTAGTGAATGGGCTGAGCGGCGGTAGACCAGGAGGGTTTGACCTCCTTGCCCGGCAGCCGCTTAACGCATTCGCTGGCATGAAGCCGTTTCAAGAAGTGATGTCGCATCACCATCAACACCACATTCATCCGCCTCATGGGAAAATGAAGGATCGCTACTCGTGCAAATTTTGTGGAAAGGTGTTCCCCAGGTCTGCAAACTTGACGAGGCATCTCCGCACACATACCGGCGAACAACCCTACAAGTGCAAATACTGCGAGAGGTCATTCAGCATCTCTAGTAATCTTCAACGTCACGTTCGCAATATTCACAACAAGGAAAAACCCTTCAAATGTCCTCTTTGCGAACGTTGTTTCGGCCAACAGACCAACCTCGATCGTCACTTGAAGAAACACGAGGCTGATGACGGCAGCGGTGTAGTTGCCGTAGCCGATTCACCAGGAAGTAGCAACGAAAATGAACGGGAAGACTCGTGCTTTGACGAGATCAGGTCGTTTATTGGCAAAGTGACCGAAGGAGACGGATATGGAATCCCGCATAATTACCCAGCGTATCTACCTGAGCGATTACACGACCTTCATGACCCGAAGATAGAGGGAGATtacgacgaggacgaggatAGCGAAGAGGGAGTATCTCCCCTTGAAGAAGCGGACGTTATGTCGCCCATGGATACGAAAGAATCACCCCCGCCCCAGTACGAGCTCAAGCTTAGGGATAAGCAGGAATTGCTCAACAACAATACGGCCGAACCAGTGATAGAGATATCAACATAG
Protein Sequence
MGGICCALDTGQRAPPSITLCHYAFSSGAESTGSSTNPPTKAPKMEMEEVYLPWTFSGFLSVNETPVSIWFRAISFNWKISLLKLCYGLVDSVPPIFLIRWVKAERGVRCVVHGPYGRKLPRGDDTQQTPWFNAVNVKLDFKGYRLWSETKLKSIHIRISGSGVRGWLDASHEASNWLKYVRSTESPHAVNMRHVLIGGQVVYETIRDIAAGEELLLGHREPLQLQDMLGENTAEDRSDRETASQHSGTVDEDREEDEDGDIRCTVCDKPFQDIDLLDGHLVTCHRYPAEQYRCETCHRGYAWRPLVVRHRSIVHGDLKKYQCENCTKVFTDPSNLQRHIRAHHVGARSHACPDCGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHRRMHADCRAQIKCGKCGQSCSSASSLTKHKRFCDSTGPPGPTGAMPQLPASGPNPFLVYPRPPGSLPGSLPFYPPSLMGPYPGIFSTTQNFFNSSLVFPPKMEEPEKRCDSPKKERFTPPRIPTHHNKVSPSTAEEATSTFRPSPARPPVQPTPESDEEAPSKQPKQPEKNVKVEAMEESADQPLDLRVETRRRQTPSVAGSHSPSPVLMVEETQAEPWKVKDEDRMETGVKELVISPVCSVAEQQPPTNATPHMAYPRPIRPSFLEAMYCAPSGTFPGFPGGPPPPCGSEPRLLPPPPPFGHMRGSFPFLAPLVNGLSGGRPGGFDLLARQPLNAFAGMKPFQEVMSHHHQHHIHPPHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKEKPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVAVADSPGSSNENEREDSCFDEIRSFIGKVTEGDGYGIPHNYPAYLPERLHDLHDPKIEGDYDEDEDSEEGVSPLEEADVMSPMDTKESPPPQYELKLRDKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01414411;
90% Identity
iTF_01414411;
80% Identity
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