Malb002416.1
Basic Information
- Insect
- Macrophya alboannulata
- Gene Symbol
- -
- Assembly
- GCA_949628255.1
- Location
- OX451206.1:22672482-22673676[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00017 0.021 16.1 1.2 2 23 96 117 95 117 0.96 2 10 4.7e-07 5.9e-05 24.1 1.5 1 23 123 145 123 145 0.98 3 10 0.00011 0.013 16.7 0.9 1 23 151 173 151 173 0.98 4 10 0.016 2 9.9 1.8 3 21 181 199 179 202 0.88 5 10 4.8e-05 0.0061 17.8 1.3 1 23 207 229 207 229 0.97 6 10 1.2e-06 0.00015 22.9 1.2 1 23 239 261 239 261 0.97 7 10 3.7e-07 4.6e-05 24.5 0.6 1 23 267 289 267 289 0.98 8 10 4.5e-06 0.00056 21.1 1.3 2 23 296 317 295 317 0.97 9 10 1.9e-05 0.0024 19.1 4.8 1 23 323 345 323 345 0.98 10 10 0.00021 0.026 15.8 0.2 1 21 351 371 351 372 0.96
Sequence Information
- Coding Sequence
- ATGAATTCTTTTGCTTGTTATTCTTCATTCCTCTCGTTGATTAATCCCTTTTATATTGATTTTCAGATCAAACAAACCCAAAGAGAAGCCCTCGGCCAAGAAACGAGGACATCCCAAACCAGAGAACCCATCAAAGGAAGAATTTTGGTGATCGTCGACTCGCTTGTCGAAGATAACAACGCGGTAGTGCAGCCCGCTAAATTGCGCGACGAGGATCCGCTGCTCGTCGGAAACGAGAAAGAGTCCGTTTCATTGATTGACGCTCAGTCGGCCGTAAAGAAATGGAAATGCAACAATTGCGATAGGATATGTGGAAACAGAGAGCTGCTACGTAAGCATCAAGCAGTACACAGCAAGGAGTTTAAATACAGCTGTagtatatgtgaaaaaaagttcaagAGGTCTAGCGAGCTTAAGGTTCACGGTAAAAGTCATTCAAAGGAAAAGAACTTCATCTGCGATATTTGCTCCAGCGCTTTCAAGCTCAAATCACAATTGACAATACACACCAAACGGCACAACAACAAGCATGATATCATATGCGATCTTTGTAAGAAGGGTTTTCACACCAACGGCGATTACAAGTCTCACAAATTTGCCAAACACGGCATGAGCGGACACGTTTGTTCAACTTGCGGCAAAGCTTTCAGATCTGAAAGCATACTAAACAAACACTCCAGGATACATCAGCCTAATTACGAACCGGACAGACCTCATCAGTGTGAAATGTGCGGCAAGATGTTTGCCActaaaaaatcgttgaaaatacACGGCAATATCCACACTGGGGAGAGAAGCTATTCTTGCGATCAGTGCGGAAAGACTGTAAGAACCAGAGCCTCTCTTAGAGATCATATGCGTCTTCACACTGGACAGAAACCGGTTGTTTGTCGTTATTGCAAAAAGGGATTCACCAAGAGATCGACAATGACTGTACACATGAGGATACATACAGGCGAAAGACCCCACAAGTGTGATACTTGCCAAAAAACATTCACTCAAAGAACTAGCCTCGTTATCCACAGGAGATACCATACAGGAGAAAGACCCTATCAATGCCAGGCTTGCTCTAAGGGATTCGTATCATCCGCCCAGCTAAAATTACATCAAAATTCTTGTTGTTGA
- Protein Sequence
- MNSFACYSSFLSLINPFYIDFQIKQTQREALGQETRTSQTREPIKGRILVIVDSLVEDNNAVVQPAKLRDEDPLLVGNEKESVSLIDAQSAVKKWKCNNCDRICGNRELLRKHQAVHSKEFKYSCSICEKKFKRSSELKVHGKSHSKEKNFICDICSSAFKLKSQLTIHTKRHNNKHDIICDLCKKGFHTNGDYKSHKFAKHGMSGHVCSTCGKAFRSESILNKHSRIHQPNYEPDRPHQCEMCGKMFATKKSLKIHGNIHTGERSYSCDQCGKTVRTRASLRDHMRLHTGQKPVVCRYCKKGFTKRSTMTVHMRIHTGERPHKCDTCQKTFTQRTSLVIHRRYHTGERPYQCQACSKGFVSSAQLKLHQNSCC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01414399;
- 90% Identity
- -
- 80% Identity
- -