Malb007885.1
Basic Information
- Insect
- Macrophya alboannulata
- Gene Symbol
- -
- Assembly
- GCA_949628255.1
- Location
- OX451207.1:12557505-12571133[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 29 8.2e-06 0.001 20.3 1.0 1 23 223 245 223 245 0.98 2 29 0.0035 0.45 12.0 1.9 1 23 268 291 268 291 0.96 3 29 0.0003 0.038 15.3 1.0 2 23 298 320 297 320 0.96 4 29 0.0014 0.18 13.2 0.5 1 21 340 360 340 361 0.95 5 29 0.0046 0.58 11.6 0.1 2 23 457 478 456 478 0.95 6 29 0.033 4.1 8.9 0.2 1 23 484 507 484 507 0.87 7 29 0.00015 0.019 16.2 0.1 1 23 575 598 575 598 0.96 8 29 0.031 3.9 9.0 0.4 1 23 604 627 604 627 0.96 9 29 0.16 20 6.8 1.5 1 23 640 662 640 662 0.97 10 29 5.3e-05 0.0067 17.7 0.8 3 23 707 728 705 728 0.96 11 29 0.012 1.6 10.2 1.1 2 23 792 815 791 815 0.94 12 29 4.1 5.1e+02 2.3 0.0 2 23 824 846 824 846 0.84 13 29 0.03 3.7 9.1 0.1 2 23 853 875 852 875 0.95 14 29 1.7e-05 0.0021 19.3 1.2 1 23 883 905 883 905 0.98 15 29 3.7 4.7e+02 2.4 1.4 3 23 938 960 936 960 0.90 16 29 0.00027 0.035 15.4 3.3 1 23 963 986 963 986 0.97 17 29 0.009 1.1 10.7 0.5 2 23 993 1015 992 1015 0.95 18 29 0.0042 0.53 11.7 5.1 1 21 1042 1062 1042 1063 0.95 19 29 0.0035 0.44 12.0 1.8 2 23 1077 1098 1076 1099 0.93 20 29 1.9 2.4e+02 3.4 2.7 1 23 1102 1124 1102 1125 0.95 21 29 0.066 8.3 8.0 3.0 2 23 1132 1155 1131 1155 0.93 22 29 1.3 1.6e+02 3.9 0.2 2 23 1163 1185 1163 1185 0.95 23 29 3.2 4.1e+02 2.6 0.0 2 23 1192 1214 1191 1214 0.88 24 29 0.3 37 5.9 2.7 2 23 1223 1245 1223 1245 0.96 25 29 0.1 13 7.4 0.3 2 23 1251 1273 1251 1273 0.95 26 29 0.65 82 4.8 1.3 2 23 1428 1450 1427 1450 0.93 27 29 1.8 2.3e+02 3.4 0.3 2 23 1457 1479 1456 1479 0.94 28 29 0.91 1.1e+02 4.4 2.5 1 23 1490 1512 1490 1512 0.97 29 29 1.3 1.6e+02 3.9 0.4 3 20 1521 1538 1521 1540 0.95
Sequence Information
- Coding Sequence
- atggAGTCCAAGGAACGGTACGCCGAGATGTGCAGGCTATGCGCTTCCTACGACGCTATTAAAATGGACATTTTTGGTCAAGAGGGACGGAGTCGACAGCTAGTCGACAAAATTCAGACCTGCCTTCCCTTCAAGattgcAGAAAATGACAGACTGCCAAAATGCGTGTGTTATCGATGCATGTACaacttggaaaatttttacgacTTTCGAACAGCATGTATTAACGCTGTTGCCTTGCTTGAGAGATATTTGCCACCCTGTCACACTGACAACGGAGATGGTAGACAAAATAATAACCATCCGTTTTCTCAGCTTCGTTCAGAGCTGCttaaggaaaaagaaaacatgCCAATACTTATTCCCGAGGCACCGATAGTAAACCCAAATGGCGCTTTAGGAACTCCGCCTAGATTGAATTCAGATGGAGAAGCAGATCATGAGATTGAAGAAATACTTTATCAGGGTATCAGTGATGATGgTGCAGATGATCACGACGATCCAAAATCTGACGAATATGAAATGGACATGGAAACAAATCCCAGTGACTTTTTGGAAATGACATCAATGGTTACTGAGGATGTAGATGAAGGAGATTCTGCAAATATAACGCCTGTTAATAACGAATCCACCCTATTTCAACATACTTCTGAACAACACGAAGTATATGTATGCTCATTATGCAACAAAGCATTCAGTTCAAAAGGACATTTGTCACTACATGCTAGAATTCATGTCGGAGCTGGAGATATCGTCGGTGAAAAAGTCATAACTGACGATCATACTTCTTACAAAAGACCCTATCAATGCGATTTATGTAACAAATCTTATTCCACTGCTAAACATAGATGGGGTCATGTATCTACAACTCATAGGGGACATCCAGCCGTAACGTGCAGGTACTGTTCACGGATTTATTCGACAAGAACTAATCTTGAAGAACACATAAAATCACGTCACGCAGGACTACCTCCGCCGCCTGATGTGCCTATTTCCTATATTCAACAAGACAATAAGTTCCAGTGTAGAACGTGTCCGAAAATGTATACAAATGTGACCGATTTGAATAAGCATAGTAGAGTATGTGCTGGAGATAGGAAAAAGGAATTAACCAGTAGGAATTCTGTACTGAAAAGAAAAGGCGCTGTTGATACATCCGATTTATCGAGTATAGATTCTGACGATGGTGGCAAAGATTATAGAGACGCCGAAGCTAAGTTGGCTAAGAATCCTCAGTTAACAATACTCAAACAAGCTTTGACAAAAAGAGATAATTTGCAAAGAGATTATGAAGAAACTAGGACAAATCATAAGCCGAAGAAAATATCAAGAACAGACAGCAGCGAGACAGATGGGCAGAAGAGGTGGTACTGTGAGACATGTCCGCAGAGTTTTATATCTGTAGATAGTCTAAAGGAACACGAACTCATCCATGATGCAGACAAACCTTTTGTTTGTATCTTGTGCGAAAAGGATTTTACACTGAAATCATCGCTGAGTAGACACATCGTAGCATCCCACGGCGTAGATCCGAGTCCTATAATTGATAGTGACAAATGTCTCAAAAGGCCGGCTGTTTCGCAGGCTTTAAACAAGCAAATAGAACGGGCAATAAACGATAATAGAGAAATTAATGAATCATCATCTTCTCCTCGGGGTATTCCTGAAAACGAGTCTGAACATGACAGCAGTCCTGATAATATGATCGAAATTGAGACAGTTTTTGTGTGCGAGATCTGTACTCGCGATTTCAACGATCGTGCTTCGTTGTGGCTACATATTAGAGCAACTCACAAGGAGTATGCAGCATTTGCATGCGGTGTCTGCTTGAAGATTTGTGCCGATAATACACAGCTACTAAATCACGTCAACATGTATCATGGAGGATCTAAGTTACAAGTTTCTGAGCAAAGAAGGTACAGCTGTACGATTTGTGGGAGGCAACAtgattcgagaaaaaaattgattacgcATGTTTCTATACACAACGTTGACCCCGGCTATGATCCAGCCAGTTTTGTTCAACTAAATAGTAATTAttacaatgaaaatttcaacagcAACGAGGCAAATGATCAGACTCTGGAGTTTGATGGTGAGGATGGTGAAAAAATGGATTGCTATATTTGTTACAAGTCTTTTCCCAGTGAGGATCACCTCATACGTCATCAAAGAAATGCTCATAAGTCTGAACCACTGGCACCAATGGGAGAATCGGCTGGCAATGGAAGCGGGACTGGTTCTGTGAGTGGTAATGGAAACCGAGCACagtatcatttatttttcgtatgCGAATTATGTGGTAGTTCTCACCCAAGCAAATGGGAACGCTGGCTTCATGTCAGTAGTATTCACAGCAATGAGCCTGCTATTAGATGTGAACGGGACACCTGtggtaaaatttttgctaCAAGATCACTGCGCAATGATCATATTCAACATCATTCTGCTCAAGGCGCTTCGCCGAACACTTGTGAAATATGCGGCAAACTTTGGGGTAGTCGAGTTGATTATTGGAAACATGTGATGGGCGTTCACTCGGATACTGTGCCTTTAATTTGTGGAGTTTGTCTTAAGGTTTTCCCAGATGTCATTCAACTCAGTACTCATGTAAAAACCAAACATTGGCCACTTACAAATGGGGATTTTAGTTGCGATATTTGTGGCAGACCGTATTCtaacaaatcaaaaatgtcTAGGCATCGAAAAATTCATGGGTTAGATGTAGACAACTACATAAATTACAGTATCCATGAATCAATTACCGACTCTACGAGGATTGACCATAGCATTAATGACTCAGATTTGAACTGCGAAATGTGttctaatttgaaattttcagaattagaAGAACTGTGTAATCACAGACGAAATGTCCACAGTTTATTCCCTTGTGATTTGTGTAACAAGTGTTACGGGAGGACGTCACATCTGTGGAAACACGTTAACAGAGTCCATAAAGGACATGAGGATGTGACATGTAGGTACTGTTTAAAGACAAGTGCATCAAAGGAACATCTGGTCGCTCATATTGCTAAGATTCATAGGTATGAACCAGAGACCAAAAAGGAAATAAGAGAATCGTCGAATTTCAAGTCTGCTAATATGGATGACGAAACGCCCCATCATTGCGAAAAATGTAACAAAGGCTTTCACAAGCGATATTTATTACGTCGCCATATGAAGGGGTGTCAGAACTACAGGAAAGATCCTGGAGCATTGTTAACTCGGTGCAGAGCATGCGAAAGAATATTTAAAGATCGTGCCAGTCTACAAAAACATATAGAAAATCATCATAGCACTTACACTTGTCATTTATGTAAAGAAGATGTAACTTCGAAGTTAGGTATTATGACTCACAACAGAGTTCATCATATGAATCATCCTGATTTGACTTGTGATCACAGCAATTGCAAGAAATTATTTAGAACTAGAGAAGACTTGGAATCCCATAAGAAAGATCACAAGTATCACAATACACCGAATGTTTGTGATTTTTGTGGGGACACTGTCGAAAACAAGCTCAAATTGAAGATGCACATATTGTCGCTACATCGAAATGAGATTGGTGTTTCATGCGGGGTTTGTTTAATTCCAATGAAGGATCCCAAAGAATTAAAAAGACACGTTGAAGAAGTCCATGATCACATTTTATCGAAGCCAAACACTTGTCAAGTATGTGGGAAGCAGTATGCTTCAAAGTGGAAGGCTTTTGATCACACCAAGAAGTGTCATGGGAAAGTATTCAGAACTTGTAAACAGTGTCTTGCTGTTTTTACCAAAGATGAGGAGTTGAGAAATCATTACGCTAGCATTCACAATGTTCCAAAAGATCAGCTGTCTGGCTTTGATTATAGATTGGAAACCTCGACCGGGAAACAAGATGATTACGAATCAGCAGAGTTACATATTAAAGAAGAACCGGACGATCTGGACTTTGACATAGATGCTTGCGACGAAGATTCTAATGACCGGAAAAGAAAGAAGCCTTTAACTGACACGTTTGACTGCAATTTATGTCAtgagatatttttgaatagtGAAACGTTGTCTCAACATTGTCATAACGTCCATAACATGAATCCTGTTAAAAGATTGAAGAAATCAAAGAAAGAAGGCTTcggcgATTTCAATCTgtttgaagatataaacatgCAACTGTCAGGTCAAAAACCTGTGCCTGATCTAATGCCAATATCTTCAGCAAAAGGACATTCAAGTAGCAAATGCTCGCGTAAAGATTCTAGAAAAGTTTACGATGAATCTACAAATACTGAATGTGCCTGTGAAGTTTGTGGTAAGCAGTGGCCAGCAAAAAAGCACTTGTGGCAACATTTGATTCGTTTTCACAGAGCAGAAGCAGCCGTTACCTGTGGTGTATGCTTAAAGCTATGCCAAACATACGAGGACTTGGCAAATCATTTGAAAGCAGCTCACGAAGCAATTTTAACTGGCGAAGGAAACAACTTTACATGCAAAACTTGCGGGAGATATCACAATGCACGAAGTAAATTGTTGTTACATATGAGTAtccatattaattataatggTAGCGAGTGGTGTCAGAATTGCCATCAAGGTTTTGAAGACGGAGAAAAGTTGAAAGAGCATTTGGAAAATTGTACTGGAAAACAAATCGAATTTGACGATCACAGTAATGACATTGATGCAagagttaaaaatgaaaatgacaaTGAAGATAAGGGTAGCTTGATAGATGATGATAATTCGTTGATGGAGGAAGTAGAAGAGGTAGAATTCGAGTCTGAGGTAGAAGGTGATGCGACAGAAAATCATGACGATAGTAACAGTGATAATTCCGAAAGCGAAGCTAGCAATGACAGCATAAGCGACGAGGAGGAAAATGACGATGACAATGAAGTGGAAGAGGACGACGTTGATGAAGAAAACGAACTCGATGATGAGTCTAGAACACACAGTAGAGTAACTGGAGATGTTAGCAGTGAATCACACAGCGAAGACGAAGATTCTGAACATCCCGGTGAAGATTTATCTGAACACagtgaaaatgatcaaaacgATAAGGAAACAAACAATATAAGCCTTCGCAGCGGAACTGACGTAACAAATGTCATAGAAAATGAGGACTGTGAAGATGACAAAGTTcagaagcaagaaaaaattgcgGATACAaacaaaagttcaaaaaatcaatttattgagTCAGACATAGATCAGAATTCTCGAGAAATTGCAGATCATTCACAATCACAGAGTCTTAATGCAAAAGAATTCGAAGAAAGTCCTTGCGAGCTACAAAATCAAGCTTTGTTCAAAAAAGAACCTGGAGATTACTCTGATGATGAAGGTCCACCTATATTAAGCCCAATGGTACCATTGCCTGTGGTAAATGATACAGAAGAGCCAAACCTGGATCACTTAGATAAAGTCCAGCATAAGTTAAGTCCAATGGTACTAATTTCTTCCAATCCTGAACAGCCTGCAGTCAAGTGTGAGTTGGAGcagatcaaaaatgaaatagaaaagggAGAACCGTCATTTTCAGCATCTAATTTGATTGAACTTAATGAGAGTACCAAAGCAAGTGGAGATCCAGATGTGGCTGCTGACATTTTAACAGAAATACTGGAATCCAATTCAGATAACGAGCAAGAAGAAAAGGAACTtcaaaatgatgataatgaagCTTCAGAAGTTGAAGAGAAAGCTTCCGAAAATGAAGAGATTTCCGAAAATGAGAATGCCGCAGTAGATGTAGACGAGGAAGAAGGAGAGGAAGGGAAAGaggcagaagcagaagcaCAGGCAGAGGAAGGAgcggaagaggaagaggaagaggaagaggaagaagaagaggacgAAAAGGAAGAAgcagaggaagaggaagaagaagagggagacgaagaagaagaagaagaagaagaagaagaggaagaggcagaagaagaagaagaagaacagtCAGAAGATAATCCTCACGATGAAGATACATCGGAAAATTGCGGTGAACAAGGAAAtgattttgaagaaatacAAAATGCCATAAACATAACAGAGGATATGTTTGAACAGAATTCAGATAGCGAAATAGAGGATATGGAAATAGAAGAGAATACAAACACTGTACAAATACCCAATTTAGATGGAACTGTACTTATGGTAGCCAACGATGCAGATGGTAATCAGATTTTGATACAGCGCAATGTCTCTGATTTACCCAACGAAGATTCGAATCCCGAAGTGACGGAGTATATTTTAGAAGGTGAAAACGAGTACGAAATAGATAACTATGAAATGGCGTCGAACGATGAAGATATAACACAACAGTTTGACAATAGTCCCAATATTTCGGAGGAAGAAAACAATGTTGAAGCAGCGGAAGACGCGCAGATATCGATTATGAGTGCCAAAAGTAAAGTGTCAAGGACGTAA
- Protein Sequence
- MESKERYAEMCRLCASYDAIKMDIFGQEGRSRQLVDKIQTCLPFKIAENDRLPKCVCYRCMYNLENFYDFRTACINAVALLERYLPPCHTDNGDGRQNNNHPFSQLRSELLKEKENMPILIPEAPIVNPNGALGTPPRLNSDGEADHEIEEILYQGISDDGADDHDDPKSDEYEMDMETNPSDFLEMTSMVTEDVDEGDSANITPVNNESTLFQHTSEQHEVYVCSLCNKAFSSKGHLSLHARIHVGAGDIVGEKVITDDHTSYKRPYQCDLCNKSYSTAKHRWGHVSTTHRGHPAVTCRYCSRIYSTRTNLEEHIKSRHAGLPPPPDVPISYIQQDNKFQCRTCPKMYTNVTDLNKHSRVCAGDRKKELTSRNSVLKRKGAVDTSDLSSIDSDDGGKDYRDAEAKLAKNPQLTILKQALTKRDNLQRDYEETRTNHKPKKISRTDSSETDGQKRWYCETCPQSFISVDSLKEHELIHDADKPFVCILCEKDFTLKSSLSRHIVASHGVDPSPIIDSDKCLKRPAVSQALNKQIERAINDNREINESSSSPRGIPENESEHDSSPDNMIEIETVFVCEICTRDFNDRASLWLHIRATHKEYAAFACGVCLKICADNTQLLNHVNMYHGGSKLQVSEQRRYSCTICGRQHDSRKKLITHVSIHNVDPGYDPASFVQLNSNYYNENFNSNEANDQTLEFDGEDGEKMDCYICYKSFPSEDHLIRHQRNAHKSEPLAPMGESAGNGSGTGSVSGNGNRAQYHLFFVCELCGSSHPSKWERWLHVSSIHSNEPAIRCERDTCGKIFATRSLRNDHIQHHSAQGASPNTCEICGKLWGSRVDYWKHVMGVHSDTVPLICGVCLKVFPDVIQLSTHVKTKHWPLTNGDFSCDICGRPYSNKSKMSRHRKIHGLDVDNYINYSIHESITDSTRIDHSINDSDLNCEMCSNLKFSELEELCNHRRNVHSLFPCDLCNKCYGRTSHLWKHVNRVHKGHEDVTCRYCLKTSASKEHLVAHIAKIHRYEPETKKEIRESSNFKSANMDDETPHHCEKCNKGFHKRYLLRRHMKGCQNYRKDPGALLTRCRACERIFKDRASLQKHIENHHSTYTCHLCKEDVTSKLGIMTHNRVHHMNHPDLTCDHSNCKKLFRTREDLESHKKDHKYHNTPNVCDFCGDTVENKLKLKMHILSLHRNEIGVSCGVCLIPMKDPKELKRHVEEVHDHILSKPNTCQVCGKQYASKWKAFDHTKKCHGKVFRTCKQCLAVFTKDEELRNHYASIHNVPKDQLSGFDYRLETSTGKQDDYESAELHIKEEPDDLDFDIDACDEDSNDRKRKKPLTDTFDCNLCHEIFLNSETLSQHCHNVHNMNPVKRLKKSKKEGFGDFNLFEDINMQLSGQKPVPDLMPISSAKGHSSSKCSRKDSRKVYDESTNTECACEVCGKQWPAKKHLWQHLIRFHRAEAAVTCGVCLKLCQTYEDLANHLKAAHEAILTGEGNNFTCKTCGRYHNARSKLLLHMSIHINYNGSEWCQNCHQGFEDGEKLKEHLENCTGKQIEFDDHSNDIDARVKNENDNEDKGSLIDDDNSLMEEVEEVEFESEVEGDATENHDDSNSDNSESEASNDSISDEEENDDDNEVEEDDVDEENELDDESRTHSRVTGDVSSESHSEDEDSEHPGEDLSEHSENDQNDKETNNISLRSGTDVTNVIENEDCEDDKVQKQEKIADTNKSSKNQFIESDIDQNSREIADHSQSQSLNAKEFEESPCELQNQALFKKEPGDYSDDEGPPILSPMVPLPVVNDTEEPNLDHLDKVQHKLSPMVLISSNPEQPAVKCELEQIKNEIEKGEPSFSASNLIELNESTKASGDPDVAADILTEILESNSDNEQEEKELQNDDNEASEVEEKASENEEISENENAAVDVDEEEGEEGKEAEAEAQAEEGAEEEEEEEEEEEEDEKEEAEEEEEEEGDEEEEEEEEEEEEAEEEEEEQSEDNPHDEDTSENCGEQGNDFEEIQNAINITEDMFEQNSDSEIEDMEIEENTNTVQIPNLDGTVLMVANDADGNQILIQRNVSDLPNEDSNPEVTEYILEGENEYEIDNYEMASNDEDITQQFDNSPNISEEENNVEAAEDAQISIMSAKSKVSRT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -