Malb002412.1
Basic Information
- Insect
- Macrophya alboannulata
- Gene Symbol
- zfy1
- Assembly
- GCA_949628255.1
- Location
- OX451206.1:22659462-22665196[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.00037 0.047 15.0 1.1 2 23 68 90 68 90 0.96 2 18 1.8e-05 0.0023 19.2 0.5 1 23 96 119 96 119 0.97 3 18 0.0096 1.2 10.6 0.3 2 23 127 149 126 149 0.93 4 18 0.0068 0.85 11.1 0.8 2 23 156 178 155 178 0.95 5 18 0.071 8.9 7.9 2.6 2 23 183 204 182 205 0.94 6 18 0.0037 0.46 11.9 0.3 1 23 215 238 215 238 0.95 7 18 0.00023 0.029 15.7 3.9 2 23 245 267 244 267 0.93 8 18 9.4e-05 0.012 16.9 2.4 1 23 273 295 273 295 0.96 9 18 6.6e-05 0.0084 17.4 1.1 1 23 301 323 301 323 0.99 10 18 0.65 82 4.8 1.1 3 23 427 448 426 448 0.84 11 18 7e-05 0.0088 17.3 5.2 1 23 454 477 454 477 0.96 12 18 0.4 50 5.5 7.4 1 23 483 506 483 506 0.95 13 18 6.6e-05 0.0084 17.4 1.2 1 23 512 534 512 534 0.98 14 18 4.6 5.8e+02 2.1 0.3 3 22 541 560 539 562 0.80 15 18 0.00036 0.045 15.1 1.1 1 23 569 591 569 591 0.97 16 18 2.4e-06 0.0003 21.9 0.5 1 23 595 617 595 617 0.98 17 18 6.7e-05 0.0085 17.4 0.4 1 23 623 645 623 645 0.96 18 18 1.6e-05 0.002 19.3 0.3 1 23 651 674 651 674 0.97
Sequence Information
- Coding Sequence
- ATGGTTCAGAGAGCTGGAGAAAAGTCGATCTGGGTACCAGCTCCGAAGGTGGAAATGCACAGTGATTCAGAAGAGATTATAAAGTCTCTGGAGGATGCCGAGGAGGGCGATAGGCGGCccgaaaaaaaggagaacgGTGTTTTAAAAGATGGAAAGGCTCttataagaagagaaaaacaatCCGAAGCTTCTGTAGAACCGAAATGTGAAGCTTGCCGAAAGACGTTTGCTAGTAAACGGAAGCTGACCGTTCACATTAAATACGTACATTCGTCGCTGCGACCATTCACCTGTAAAATATGTTCATTGgcttttaaaatgaaaaatgcatTGAAGAAACATATCCAAGTGATACATGAGGGATCCTATGAATTACTTCCGTGTAAAGTATGCGGCTACAAAGCTAAGGACAAATCTAGACTCGAAGATCACTACGTTAGACGGCACACTGACATATACGCTACTTCTTGTTACATATGCGGTATGCAGCTGAGATTCAAACGTGATTTAACTACTCACATTAATCAGATGCACTGCGGTCCTGTGGTGTGTGAAAAATGCGGCGACGTACTTCCTAATTATAGATCTCTCTGCAATCACAAAAAGACTCATCACGCGGGTGGCGCTagaagaaacagaaacttTAAATGCGGTATTTGCTCCAAGGGATTTGCCTCTCAGGAATCTGCCGACGCTCATAGAACTAAGCAGCACAATAACGGGGAAAGCTGTTACTGTGATCTCTGCGGGAAACCGTTTACCGGAAAATACGCTTTGACTCATCATATTCATAATGTTCACAGGGAAGACAGGCCCTACTTGTGCCCAGTCTGCAGCAAAACATTTAAAATGCACAGCCTGCTACAGCTACACCTCTTCACTCATACAGACGTAAAACCATACCGATGCGATATTTGTGGCTCTACTTATACTCAAAGAGGCTCTATGATGCTCCACAGGCGGAAACACCCTGGAGAATTGCCACCTGTACCTCCGATAAAGCTTGACTTTTTGCTCAAGAGTATACAGCCTAAAATAAACGAACTTGCCAAGACAAACGGGGCCAAGAATGGTAGCGAGAACGCCGAAGTTCAACTGCGGAATAGCAAGAAGATGGAGAGGAGGTCGGTGAGAAGGGGAACTTTGTGTGATAGGCTGTTGAAGAGAGGCATAGTAGGTTCGCCGAAAAGGGATGGAGAAAGAAACGAGGTGAATAGAAATTCTCAGGCATATGGAAAAGCCAGATccttgaaaagtaaaaagaaagaaaaagtctTCTGTGAAATATGCAAAGTCAGTTTTAACGTCAGAGGTTCAGAGTACAACAAACACATGCTTAAGCACAGTAATTTGTACGGGTTTCAGTGTGACgtttgttcgaaaaaattcaaacacaaAAACAACATGAAACGGCACAAAATCAAAGTTCACGGGGAAGCTCCTGTGTACAGGTGCCAATTCTGCGACTTTACCACTATTCACTGCTCATATTTACAGGTACACTTCACTAGAAAGCATACCGGCGATTTTCAATACGCTTGCGAGAAGTGCAACAGAAAGTTTAGAATAAAAGCCGATTATACAAAGCATCTAATAACGCATGACGGCGATCCTTCTATATGTGATGTATGCGGAGCAACGCTTCCGAACAGGATGtctctttattttcataagAATTATAAACACCGTGTTAGAGATGGAAGGTTTCAATGCCCAATTTGCAAGAAGAAATTGCAGAGTCAAAAGAATCTGGACAGCCATGTGCAGCAGCACGGTCTGAAGTATATGTGCGAAGAATGCGGGGTAGAGCTGACTCGGAAGACTGCGTTGAAGAAACACATGAAAACACATTCAGGAGAGAAACCTTACCTCTGTCACATATGCGGAAAGGCTTTTGCCAGCGCTACAGGGAGAAAAGTTCACCTTCTTACACATTCTGGCGTTAGACCATACATCTGTACAGTTTGCGGACAAAGCTTCACTCAGCGGCCTGCTCTCTCTGTAcattggaagaaaaaacatCCCGATGTAACCGACGCCCCTCCCTCTGTTTCCATAaggaatattattgaaaacgTGAACCGTACCAGTAAcagaataaataatgattag
- Protein Sequence
- MVQRAGEKSIWVPAPKVEMHSDSEEIIKSLEDAEEGDRRPEKKENGVLKDGKALIRREKQSEASVEPKCEACRKTFASKRKLTVHIKYVHSSLRPFTCKICSLAFKMKNALKKHIQVIHEGSYELLPCKVCGYKAKDKSRLEDHYVRRHTDIYATSCYICGMQLRFKRDLTTHINQMHCGPVVCEKCGDVLPNYRSLCNHKKTHHAGGARRNRNFKCGICSKGFASQESADAHRTKQHNNGESCYCDLCGKPFTGKYALTHHIHNVHREDRPYLCPVCSKTFKMHSLLQLHLFTHTDVKPYRCDICGSTYTQRGSMMLHRRKHPGELPPVPPIKLDFLLKSIQPKINELAKTNGAKNGSENAEVQLRNSKKMERRSVRRGTLCDRLLKRGIVGSPKRDGERNEVNRNSQAYGKARSLKSKKKEKVFCEICKVSFNVRGSEYNKHMLKHSNLYGFQCDVCSKKFKHKNNMKRHKIKVHGEAPVYRCQFCDFTTIHCSYLQVHFTRKHTGDFQYACEKCNRKFRIKADYTKHLITHDGDPSICDVCGATLPNRMSLYFHKNYKHRVRDGRFQCPICKKKLQSQKNLDSHVQQHGLKYMCEECGVELTRKTALKKHMKTHSGEKPYLCHICGKAFASATGRKVHLLTHSGVRPYICTVCGQSFTQRPALSVHWKKKHPDVTDAPPSVSIRNIIENVNRTSNRINND
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -