Basic Information

Insect: Macrophya alboannulata
Gene Symbol: -
Assembly: GCA_949628255.1
Location: OX451209.1:21319593-21321992[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00074 0.094 14.1 0.1 1 22 135 156 135 158 0.91

2 13 1.6e-06 0.0002 22.5 1.3 1 23 165 187 165 187 0.98

3 13 2.2e-06 0.00027 22.1 6.6 1 23 193 215 193 215 0.98

4 13 0.00016 0.02 16.2 6.1 2 23 232 253 232 253 0.98

5 13 2e-08 2.5e-06 28.5 3.1 1 23 258 280 258 280 0.98

6 13 4.6e-07 5.8e-05 24.2 0.8 1 23 285 307 285 307 0.98

7 13 1.6e-08 2e-06 28.8 2.5 1 23 313 335 313 335 0.98

8 13 2e-05 0.0026 19.0 8.1 1 23 391 413 391 413 0.97

9 13 1.3e-05 0.0016 19.6 0.8 1 23 480 502 480 502 0.98

10 13 1.2e-05 0.0015 19.7 3.9 2 23 518 539 518 539 0.98

11 13 1.3e-06 0.00016 22.8 1.5 1 23 544 566 544 566 0.98

12 13 3.3e-05 0.0041 18.3 3.1 1 23 572 594 572 594 0.93

13 13 0.00022 0.028 15.7 5.8 1 23 600 622 600 622 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00074	0.094	14.1	0.1	1	22	135	156	135	158	0.91
2	13	1.6e-06	0.0002	22.5	1.3	1	23	165	187	165	187	0.98
3	13	2.2e-06	0.00027	22.1	6.6	1	23	193	215	193	215	0.98
4	13	0.00016	0.02	16.2	6.1	2	23	232	253	232	253	0.98
5	13	2e-08	2.5e-06	28.5	3.1	1	23	258	280	258	280	0.98
6	13	4.6e-07	5.8e-05	24.2	0.8	1	23	285	307	285	307	0.98
7	13	1.6e-08	2e-06	28.8	2.5	1	23	313	335	313	335	0.98
8	13	2e-05	0.0026	19.0	8.1	1	23	391	413	391	413	0.97
9	13	1.3e-05	0.0016	19.6	0.8	1	23	480	502	480	502	0.98
10	13	1.2e-05	0.0015	19.7	3.9	2	23	518	539	518	539	0.98
11	13	1.3e-06	0.00016	22.8	1.5	1	23	544	566	544	566	0.98
12	13	3.3e-05	0.0041	18.3	3.1	1	23	572	594	572	594	0.93
13	13	0.00022	0.028	15.7	5.8	1	23	600	622	600	622	0.97

Sequence Information

Coding Sequence: ATGCGCATTCAACATGCTGGCTGTTCTAATTGTATCAAAGAGAAATGGACCGTGAGATTGGGTTTTCAGGACAATATACTGTTCGACAGCGTAGATGGAATCAGACGTATCGTAGAAGAGCCATTAGACAAGGATGTCTCAACTCTGAGAGGATTCTTAGACTATGTCGAAACTATAACAACTCAAGAGATTAAAATCGAGATACAGGGATCGACAAAAACTAACATTGCCACTGTTTCCGTTCCTGGAAGATTCGCAGATGTTAATCTAACGGATTTAatgaaaaaagaatctCTGGGAAAATCATCGATTCAATACAGTGCTCTCCCTGAGCAACAGGATCTGTTCGCAGAGGGTAACACGGATGTTGATTGGAAGCTAAATGATGGAAATCAAAGTCTTTATCGCTGCGCTATTTGCCAGATTCAATTTTCCAGTCGAGTATCTTTGGACAGACACATTGTGGACTTACACTTGGGTACAACGGGTCGATTTCAGTGCGATATTTGCCATAAAGAATTTTCTCGAGTCTCTGACTTGGCTCGACATAAACTAATACATTCAGGCGTTAAACCATTCCAATGCAACACTTGTCATAAGCAATTTTCTAGACAAGATCATCTGAAACAGCATATACTTAGCCATTCCCAATGCTCTGATAGCGAGCTTTTCGCTTTTGAGAACGGTTTGAACAGGTGTACTATTTGCCATAAGCAATTATCGCGGCCCCAACACTTGAGAACTCATATGCGACAACATTTAGGGACTTTGTTTGAATGCGATAAATGTAACAAAAGATTTTCACGGGCTTCTCACCTCAGAGCACACATGCGTCTTCATTTGGGTACATGTTTTCGTTGTGATATTTGTCAGAAAGAATTTTCTAGACCCTCTGATCTGGACAGACATAAACTTACACATTTGGATAAGAAATTATTCGAATGTCCTACTTgccaaaagaaattttctagaAAGGATAATCTTAAAAAGCATATGCTTTCTCACGTCGAATCTATACCACCCAACCAAATTAATCACagtcagaattttttcgaggAAGATCTGTGTTtgaattcgaagaaaaattgtcaatGTACTGTCTGCATCGCGAAGATTTCATTGCCTTTGGAATTCGAGGGACATACGATTATTCACTCTGATATAAGATGCCACGAATGTCACGTTTGCAAGAAATATTTCACTAGGAAAGATCATTTGAAGAGACACCTTGCTTCGCACAAGATCTCACCTTGTGATCAATCTATCGATCAATACATTACGAGTAGAAGAACTAAAGAACAGATGCTTTTAAACGGAGTTTCAAACCCGTTTGATCCGAGAGAAAAATCGGACGGTTGCGGTGTTTGCAAATTAGAGTATAGCAGTAGgttcaattttgataaaagtatGTGTCCGCATGATTGGACAGAGAAGAAATTTGAATGTGCGATTTGTGAGAAGCGATTTAATAGAAAAGTCAGATTAAAAGAACACGTTCGTATGCATGGAGACGGTAATTTTGAACTTAATGATGGAGATCAAGAACAGAATAGATGTAATATTTGTCACAAACAATTATCACGCCCAGAACATTTGAAGGCACACATGCGACTGCATCTTGGAACGCTTTTCAAGTGTGAAACTTgcaaaaaagaattttcaagattATCAGACTTGGAGAGACACAAGCTGGTTCATTCGGGGCTTAAACAATTCATATGCATTATTTGTCACAAGCAATTCTCTCGGAAAGATTACCTAAAAAATCATATGCTTTCACACGCTAatcaaaaatcatttgaatGCGACAAGTGCAAAAAGCGATTTACCTATTTCACCAATTTGAGAAATCACTTGCATCTTCATATAGGGGGTTAA
Protein Sequence: MRIQHAGCSNCIKEKWTVRLGFQDNILFDSVDGIRRIVEEPLDKDVSTLRGFLDYVETITTQEIKIEIQGSTKTNIATVSVPGRFADVNLTDLMKKESLGKSSIQYSALPEQQDLFAEGNTDVDWKLNDGNQSLYRCAICQIQFSSRVSLDRHIVDLHLGTTGRFQCDICHKEFSRVSDLARHKLIHSGVKPFQCNTCHKQFSRQDHLKQHILSHSQCSDSELFAFENGLNRCTICHKQLSRPQHLRTHMRQHLGTLFECDKCNKRFSRASHLRAHMRLHLGTCFRCDICQKEFSRPSDLDRHKLTHLDKKLFECPTCQKKFSRKDNLKKHMLSHVESIPPNQINHSQNFFEEDLCLNSKKNCQCTVCIAKISLPLEFEGHTIIHSDIRCHECHVCKKYFTRKDHLKRHLASHKISPCDQSIDQYITSRRTKEQMLLNGVSNPFDPREKSDGCGVCKLEYSSRFNFDKSMCPHDWTEKKFECAICEKRFNRKVRLKEHVRMHGDGNFELNDGDQEQNRCNICHKQLSRPEHLKAHMRLHLGTLFKCETCKKEFSRLSDLERHKLVHSGLKQFICIICHKQFSRKDYLKNHMLSHANQKSFECDKCKKRFTYFTNLRNHLHLHIGG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00060529;
90% Identity: iTF_01412510;
80% Identity: iTF_00938923;