Mcin000581.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrocentrus cingulum
Gene Symbol
-
Assembly
GCA_002156465.1
Location
MVJL01007024.1:39441-44917[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.7e-05 0.0023 18.4 0.2 2 23 643 664 642 664 0.97
2 16 0.48 66 4.4 1.0 2 23 697 718 696 718 0.96
3 16 0.00015 0.02 15.4 1.2 3 23 727 748 726 748 0.98
4 16 0.0021 0.29 11.8 2.1 1 23 755 778 755 778 0.95
5 16 6.8e-05 0.0093 16.5 0.8 1 23 784 807 784 807 0.94
6 16 1.6 2.2e+02 2.7 1.6 2 23 815 835 815 835 0.91
7 16 3.5e-07 4.8e-05 23.7 2.3 2 23 841 862 840 862 0.97
8 16 1.2e-06 0.00017 22.0 0.2 1 23 868 890 868 890 0.99
9 16 0.02 2.7 8.7 5.3 2 23 902 924 901 924 0.94
10 16 0.15 21 6.0 1.1 1 23 930 953 930 953 0.92
11 16 0.007 0.95 10.2 3.6 3 23 975 996 974 996 0.96
12 16 1.3e-05 0.0018 18.7 0.8 2 23 1003 1025 1002 1025 0.97
13 16 2.3e-05 0.0031 18.0 1.7 2 23 1033 1054 1032 1054 0.97
14 16 0.017 2.3 9.0 4.8 1 23 1060 1083 1060 1083 0.95
15 16 0.74 1e+02 3.8 4.1 2 23 1090 1111 1089 1111 0.96
16 16 0.009 1.2 9.8 2.6 1 23 1117 1139 1117 1139 0.98

Sequence Information

Coding Sequence
ATGTCTACAAAGCTGGAAAAGCCTGCAAGTCAGGTCAGAAGCATCACTGAATTGAAGAAGGTGTTACCGAAGGTGAAAATTCTCACAAAAGCGCGAATAATTACCGAACCGAAGTCAGACAATCTTAATACCGAGGTAAACGAAGCGGCAAATCCGATGGAGGAGCTGAAAAATTACTGTCGGACGTGCGCAGGACTAAAGGTACCACTAGTGGatattttcagcaaaaaagGCTTACAAATGCGCCTAAATCAGCAATTAAAACACCTCGAAAACATTGAAAAGCACGACAGCCTATCTACACAGATGTGTATGGACTGTATTTGCGATTTAAAAATgagttacaaattttttttacaaataaaaaaggcCCAGGTGAAACTGCAGTCAATTCACGCCTCGTTGTCAACATCTGCACGGCCAGAAAATCGTAACAATCAAATGCCCTCTGTAAAAATTGTACTGCCATCGCCAATTTTATCGCCACAACAGCCTCTCTACCCAGGCGAATCTGTGGCAGGGAACATGTACGACATTTCCGACTTGGAAAATGCGTCTTCTAGTCCGggattttcattaaaatcaacagTGAGATGCTCTGAAACAACTGCGAAGTCGACTGAGAGGCTCACAAACTCCTCACCGCATGTTTACGCGCTTAAGTCATCGCAATCAGCCGTAGCAGTACTGCCCAACGATACCGCGTCATTGCTTGCAGTGCTAGAAGACGATGTAGAAAGTGCAGACCCGATTCCCGCCGATTCAGATGCTTTTAACCCGGAACAAACCCTCAACGCTACGGCTGAGGACATCGCCGAGGCGGCGGAGCTTGTACAAGACCTCGAGGAGGACAACATCGAGGCGATTGACGAGCTCGATGCGGATCATGACTACGCTTCGATGCTGGGTCCTGAACAGAGTCAGGAATTCGCGAAAGCCACGAACTTTGCCACGGCAGAAAGCACAGCAGAGTTTATCATAAAGGACGAAGACTTTACGAGCGGTATGCCGACAGAGTTTGAGATTCAGAATGAAATTGAGGCGTATGTGAAACTGGAATCACAGCCCGACGGCAGCGAGATCCCGAGCGTGAGGATCGCTGTGAAGCAGCCGAATATTTTGAAGCGAAAATCTTCGACGACAGTGGTCACAGAAGAGGAGTCGGTCACGAAGAAGCAAAAGCTAAACACGGAGAGCGTCCCGGCAAACAACGAGGGAATTATGTACGTGACGGTTAAGGGGTCGAAACCGAACGAAGTGTTGCTGgtaaaggtgaaaaaaatggacaaGGCGGAGAAGAAGGATGAGAAGAGTATGAAAAAAACGCGACCTATCGAGTTGACGTCCTTTGACCAAGTGTTGAAGGGATACACGAAGGAGCAGACGATTGACGGGGGGAAAAACGAGAATCGCGAGGCGATTATCGAAGAGCAGATTGAGCAGTACAAGAAGCGGCGCGAGCAGATTCTCGGTGGTGTGACCAATTTGCGCGAGGCTTTCAACGACGCGCCCGTGCGCTACGTTTCGTCCTACAGTGCGCCTGTGGTTACAGGGACCGTGGAACAGCCCAGCATCGAGATGGAGACTGTAGAAACCGTACACGAGCCTGCCGAGTCTCTGACGCGGCTGGCATTGATCAAGCAAAAGTGGGAAGAGGTAAAGGTAAAAAAGGAGACAATTGACCGCGAAATCGAGACACACCGCGACGGCGATCTCGAGAAAATTACGCGAATTCTCGGCGAAAAGGAGAAGAATCTGCAGGAATTTCAGGAATATTTGAAGCAGCGAAAAATTGTGATAGAACGGTTGAAGGACGAGGATATTATCACGCTGTATGACGAACGCAACTCGGCCAGTGTTGGCAAAAAACTGCCCGATCTCATCGACGAAGGTGAGGCCAGGGATCCGCTCGACGCATACGTCCTCGAGTGTGACTACTGTCCGCAGGTATTTACCAGTCGAGATTTTCTCGAGGAGCACCTGAAAAGCCACGACTTCAAGCTGGCATTCTTCTGCGAAGACTGCTGCAGCGAATTCCCGACAAATAAGGGTCGTCGGGCGCACAATATCACTTGTCTCAAGAAGCTCGTGTGTCGTTACTGCGACTTTATGCTCGCGTCAAAGGGAAAGAAACGCCAACACGAGCAGAAACACTGCGACGCCATGTACGGCCAGCTGTGCGACGTGTGTGGAGAAAAGTTCAAGCACCAAGGCACGTTGGATCAACACGTAAAGACGCAGCACATGAGTTGGGAGAAGCGATTTCAGTGTCCCAAGTGTCCGAAAAAATTTGCCTTCAAGCAGAAACTCAGTTTTCACTTGAAATCCGTGCACACGACAATGCGTGCCTTCCTGTGCGAGGACTGCGGCGCAGATTTTAAGAATCCAGCATCACTGCGACATCACCGTATCCGCAAACATCAGCCGAATGGCAACAAGCGCGAGTGTCAAGTCTGTCACAAACTCGTGCCATTCTACAGCCTGTCCAAGCACATGTACACACACAAGGCCTACACGATCCAGTGCCCGCATTGCGACAAGATGTTTAAAAACACCTCGACACTGAAGCAGCACGTGCGAATCCACGAGGACCAGCGTCAGTACCGCTGCGACACATGTGGCGTGGGTTTCAACCGACGCGACGGCCTCCGTCTGCACATGCGAGTGCACCAGAAGACAGACAGCCGCGCGCTCAAGGAGTGTTGCTGCCAGATCTGCTCGGAAAAGTTCCCCAACCACTCGATGCTCGTGATTCACCGCAACCGAGTGCACAAGGACGGCAAGCAGTACACCTGCAACATCTGCAACCGCTCGATGCTGTCTACGCGCTCGCTCGAGTGGCACATGTCGCACATCCACAATCAGGAACCTTCAGGCGACGCGAAGGATGCCGCCGACGCCGGCGAGAAGCAGCGTGTCCTCTGTACGCACTGCAACAAAACCTTTAAAACCGAGATGATTCTGCGTACGCATATTAAAAACACCCATATGGAGAAAAATCCGGTTAAATGTCCGGACTGCGACTTGACCTTTACGTCCGAGGTACGGCTGCGACACCACATGATGGTGACTCACAGTCGCTATGAAGGCACACTGACCTGTCCGCACTGCCCCAAGCGATTTGTCAATCAGTTGCGCCTCAAGACTCACATGATCTCGCACTCGGAAGACCGGCCGTTCCCCTGTGACAAATGTGGTTTCCACCTGAAGACGAAAATTCAGCTGCTAAAACACCACCAGAACCGCCACAGCGACGAGCGGCCGCTGCAGTGTCGCTACTGCTCCTGGCGCTGCAAGCAGGTCAGTGCGCTCGTTTGCCACGAGCGGACACACACGAATGAACGACCATACTCGTGTATGGTGTGCAAGCAGCGGTTTAAGTATCTCGGGGACAAGAATAAGCATGAGCGACGCCACGAGAGCCTTGGCGGCTCGGGTTTCAAGCGCCACGTGACTGAGCGCGTGTACAAGCGTCGGGATGCGGAAACTGGCTCGGATCAGGATCCCCTTGAGGACGGAGAGTACGAGACGCTCGATCCTCAGTTGACCGAGGAGCAGTACGAGCAGATTCAGCAGTTTGATGAGGACGGGCAGATTATCAAGTTTGAGACGCAAGACGCTGACGAGTACGAGCAAGTGTACGAGCAGGAGTATGATGAACAGGAGTACGACGAGACGTCGCGCGAAGCCTCGGAAGCCGCCGACGTCATTATGAGCATGGAAGATGGCACGGTTTATACCGAGGAAGTCACTGATCAGATTGAGACTGTGGAAATGATCACGGATGAGATGCTTCAGAGTGGAACAGCTGTGGTACACCTTCGGCAGAAGGGCGaggatggaaaaattcaagtgattCCTTTGATGCTCACACTGCCGAATTTAGGTGACGGTACGGCAGTCACGATCGACACTGCGCCCTTGATGTACAGCAATTAG
Protein Sequence
MSTKLEKPASQVRSITELKKVLPKVKILTKARIITEPKSDNLNTEVNEAANPMEELKNYCRTCAGLKVPLVDIFSKKGLQMRLNQQLKHLENIEKHDSLSTQMCMDCICDLKMSYKFFLQIKKAQVKLQSIHASLSTSARPENRNNQMPSVKIVLPSPILSPQQPLYPGESVAGNMYDISDLENASSSPGFSLKSTVRCSETTAKSTERLTNSSPHVYALKSSQSAVAVLPNDTASLLAVLEDDVESADPIPADSDAFNPEQTLNATAEDIAEAAELVQDLEEDNIEAIDELDADHDYASMLGPEQSQEFAKATNFATAESTAEFIIKDEDFTSGMPTEFEIQNEIEAYVKLESQPDGSEIPSVRIAVKQPNILKRKSSTTVVTEEESVTKKQKLNTESVPANNEGIMYVTVKGSKPNEVLLVKVKKMDKAEKKDEKSMKKTRPIELTSFDQVLKGYTKEQTIDGGKNENREAIIEEQIEQYKKRREQILGGVTNLREAFNDAPVRYVSSYSAPVVTGTVEQPSIEMETVETVHEPAESLTRLALIKQKWEEVKVKKETIDREIETHRDGDLEKITRILGEKEKNLQEFQEYLKQRKIVIERLKDEDIITLYDERNSASVGKKLPDLIDEGEARDPLDAYVLECDYCPQVFTSRDFLEEHLKSHDFKLAFFCEDCCSEFPTNKGRRAHNITCLKKLVCRYCDFMLASKGKKRQHEQKHCDAMYGQLCDVCGEKFKHQGTLDQHVKTQHMSWEKRFQCPKCPKKFAFKQKLSFHLKSVHTTMRAFLCEDCGADFKNPASLRHHRIRKHQPNGNKRECQVCHKLVPFYSLSKHMYTHKAYTIQCPHCDKMFKNTSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHQKTDSRALKECCCQICSEKFPNHSMLVIHRNRVHKDGKQYTCNICNRSMLSTRSLEWHMSHIHNQEPSGDAKDAADAGEKQRVLCTHCNKTFKTEMILRTHIKNTHMEKNPVKCPDCDLTFTSEVRLRHHMMVTHSRYEGTLTCPHCPKRFVNQLRLKTHMISHSEDRPFPCDKCGFHLKTKIQLLKHHQNRHSDERPLQCRYCSWRCKQVSALVCHERTHTNERPYSCMVCKQRFKYLGDKNKHERRHESLGGSGFKRHVTERVYKRRDAETGSDQDPLEDGEYETLDPQLTEEQYEQIQQFDEDGQIIKFETQDADEYEQVYEQEYDEQEYDETSREASEAADVIMSMEDGTVYTEEVTDQIETVEMITDEMLQSGTAVVHLRQKGEDGKIQVIPLMLTLPNLGDGTAVTIDTAPLMYSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-