Basic Information

Insect: Macrocentrus cingulum
Gene Symbol: mecom-b
Assembly: GCA_002156465.1
Location: MVJL01003538.1:247779-255179[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0016 0.22 12.1 0.0 2 23 121 143 120 143 0.95

2 9 0.28 38 5.1 0.1 1 23 150 173 150 173 0.92

3 9 2.1e-05 0.0029 18.1 1.3 1 23 179 207 179 207 0.95

4 9 2.6e-06 0.00035 21.0 2.6 1 23 213 235 213 235 0.95

5 9 1.3e-05 0.0018 18.7 6.0 1 23 241 263 241 263 0.99

6 9 0.01 1.4 9.6 1.0 3 21 272 290 270 291 0.93

7 9 3.7e-09 5.1e-07 29.9 1.2 1 23 665 687 665 687 0.99

8 9 5e-07 6.8e-05 23.2 3.2 1 23 693 716 693 716 0.97

9 9 5.5e-06 0.00075 19.9 3.4 1 23 722 744 722 744 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0016	0.22	12.1	0.0	2	23	121	143	120	143	0.95
2	9	0.28	38	5.1	0.1	1	23	150	173	150	173	0.92
3	9	2.1e-05	0.0029	18.1	1.3	1	23	179	207	179	207	0.95
4	9	2.6e-06	0.00035	21.0	2.6	1	23	213	235	213	235	0.95
5	9	1.3e-05	0.0018	18.7	6.0	1	23	241	263	241	263	0.99
6	9	0.01	1.4	9.6	1.0	3	21	272	290	270	291	0.93
7	9	3.7e-09	5.1e-07	29.9	1.2	1	23	665	687	665	687	0.99
8	9	5e-07	6.8e-05	23.2	3.2	1	23	693	716	693	716	0.97
9	9	5.5e-06	0.00075	19.9	3.4	1	23	722	744	722	744	0.99

Sequence Information

Coding Sequence: ATGATTCCAGCCGATTTATCAGTTATTTCCCGTTGTTTGCAGGTTCGCATTGTCAAAAGTGGCCTCCGTGGCTGGCTAGACGGTTCCCGCGAGGCCAGCAACTGGCTCAAGTACGTTCGTAGCACCGGCATCCCGCACTCTGTCAACATACGTCACGTACTCGTTGGAGGACAGATAGTCTACGAGACGATAAACGACATTGCAGTGGGCGAGGAGCTGGTCATGGGTGTTCGCGAGACTATAGTGATCCAGCATATGCTGCCCGAGAGCGCGACAGAGGACAGAACCGATTGCGAAACTGCGTCACAGCACAGTGGAACCATCGACGAGGACCGTGAGGACGAGGAGGACTGTGAAATTCGCTGTGCCGTCTGCGACAAACCCTTTCAAGACCTTGACTTaTTAGACAATCACCTGGTGACTGCACATCGTTATCCAGCGGAACAGCACATTTGCGATAGTTGTCCACGAGCCTACTCCTGGCGACCACTCTTGGTGCGTCATCGAGCAATTGTCCACGGTGATCTTCGTAAATATCCCTGCGAAAATTGCCCAAagACAAACAAACAACAGGTTTTCACAGATCCATCGAACCTACAGCGACACATCAGGACAAACCACGTAGGAGCGCGAAGTCACGCGTGCACAGAGTGTGGCAAAACATTCGCAACTAGTTCGGGACTGAAACAGCACACTCACATTCATAGCAGCGTGAAGCCCTTTCAGTGCGAGGTGTGCTTCAAATCTTATACGCAGTTTTCTAATCTGTGCCGACATAAACGCATGCACTCCACTTGTCGTATGCAGCAAAACTGTCTCAGATGTGGTCAGTCATTCAGCTCAGGAACATCTCTGTCGAAGCATAAGCGTTTTTGTGACTCTACTGCGCCGAGCAGAGCTCCACGACCGTCAGGAGCAATGCCGCAAATGCCTACGTCAACACCGAGCCCATATTTCGGCTATCCACGTCCACCAGTCGGACTGCCCAATGGACTGTCGCTCTATTCACCCAATTTCATAAGTGGCTATCCTGGAATATTTCCCAGTGCACCAAGTTTCCTCAATACTCCGCTGCTCTTCTCGCCAAAGCTGCAAGATCAGCTGAAGCGCAGTGAGAGTCCAAAGAAGGAAAGATTTACGCCTCCGCAAGTGCTGCTACCGGTGAATAAGATCTCTCCGGCGGCCGCAGAAGAGGCGACATCGACATTTCGACCCTCACCACCGAGACAAAATGCCCTCGCCGCGCCGAAAAtcgatgagaattttttcctaaaGCAGGAAGAAATAAAGCAGGAAGTACAGCCCGAAATACAACAAGAAATtaaacaagaaataaaaaacgagaaaCAAACGAGAGAATCCTGCGAAatcacatcatcatcatcatcatcatcgtcgtcctCAGCAGAAGAGTCGAGTGATCAACCGTTGGATTTGCGAGTTCAAACGAAAAAACGGAGAGTAACGCCACCGTGCAAGGAAGAAAAATCACCGAGTCCAATTCCACCAATACCCAAGACGGAACTCACTGTACAGGAGGATCCTCAGCCCACAGAGGTTTGTGAGACACTTGCGGTTGATGTAAAGGATGAACCAAGTCCTCAAACGCGCATCAGTCTGCCTCAGGACGTTCCGCAAACCAATACACCGCCTCACATGGCTTATCCGCGACCGATTCATCCAATGTTCTTGGAAGCAATGTATCGCGGACCTGGAGCGACATTTCCGGGATTTCCCGGCGGTCCAGCGCCGCCAAGTGCCCCCGCAGAGTCACGACTACTTCCCCCGCTGCACCCTTTTGGACCACCCCGACTTCCTTTTTTAGGAAATCTCATGAATAGCCTCGGCACGAGACCCGGTGAGGGCTTTGATCTCTTGGGCCGGTCGCCGCTTAGCGGATTTCCCGGCGTTAAGCCCTTTCAAAATGCCGTCATGTCGCCGCACCATCACCACCcccaccaccaccaccctCCGGGCAAGATCAAGGACCGATATTCGTGCAAGTTTTGCGGCAAAGTGTTCCCGCGATCGGCAAATCTCACGCGCCACCTGCGCACACACACTGGCGAGCAGCCATACAAGTGCAAGCACTGCGAGCGATCGTTCAGCATCTCCAGCAATTTGCAGCGCCACGTGCGCAACATCCACGATAAGCAGCGACCCTTCAAGTGTCCGCTGTGTGAGCGCTGCTTCGGCCAGCAGACAAATCTTGACCGGCACCTGAAGAAGCACGAGGCTGACGACGGAAGTGTGGTCGTGTCGGTGGCCGACTCGCCGGGCAGTAGCAATGACAACGAACGCGAGGATACGTACTTTGATGAGATCAGATCATTTATGGGCAAGGTGACATATGGCGGAGACAGTGCCTACGGCCTGCCGCATCACCCGGGCTACATGAGCGGTAGACTTGACGAGAGTAAAACCGAGGCTGACTATGACGATGACGATTACAGCGAGGGTGGCGTCTCTCCACTCGAAGAAATCGACACTATTTCCATCGAGGGAAAGTTATCACCTACGCAACAATACGAAATGAAGTGCAGAAATAAACCCGAGCTTCTAAACAACAACACGGCCGAACCCGTCATAGAAATTTCAACATAG
Protein Sequence: MIPADLSVISRCLQVRIVKSGLRGWLDGSREASNWLKYVRSTGIPHSVNIRHVLVGGQIVYETINDIAVGEELVMGVRETIVIQHMLPESATEDRTDCETASQHSGTIDEDREDEEDCEIRCAVCDKPFQDLDLLDNHLVTAHRYPAEQHICDSCPRAYSWRPLLVRHRAIVHGDLRKYPCENCPKTNKQQVFTDPSNLQRHIRTNHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKSYTQFSNLCRHKRMHSTCRMQQNCLRCGQSFSSGTSLSKHKRFCDSTAPSRAPRPSGAMPQMPTSTPSPYFGYPRPPVGLPNGLSLYSPNFISGYPGIFPSAPSFLNTPLLFSPKLQDQLKRSESPKKERFTPPQVLLPVNKISPAAAEEATSTFRPSPPRQNALAAPKIDENFFLKQEEIKQEVQPEIQQEIKQEIKNEKQTRESCEITSSSSSSSSSSAEESSDQPLDLRVQTKKRRVTPPCKEEKSPSPIPPIPKTELTVQEDPQPTEVCETLAVDVKDEPSPQTRISLPQDVPQTNTPPHMAYPRPIHPMFLEAMYRGPGATFPGFPGGPAPPSAPAESRLLPPLHPFGPPRLPFLGNLMNSLGTRPGEGFDLLGRSPLSGFPGVKPFQNAVMSPHHHHPHHHHPPGKIKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKHCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSVVVSVADSPGSSNDNEREDTYFDEIRSFMGKVTYGGDSAYGLPHHPGYMSGRLDESKTEADYDDDDYSEGGVSPLEEIDTISIEGKLSPTQQYEMKCRNKPELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -