Mcin010089.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrocentrus cingulum
Gene Symbol
ZNF236
Assembly
GCA_002156465.1
Location
MVJL01011613.1:46533-60164[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 1e-05 0.0014 19.1 0.6 2 23 187 208 186 208 0.97
2 28 6.3e-05 0.0086 16.6 0.5 1 23 214 236 214 236 0.98
3 28 2.6e-05 0.0035 17.8 0.3 2 23 242 263 242 263 0.97
4 28 0.0014 0.19 12.4 0.2 3 23 271 291 269 291 0.96
5 28 0.00012 0.016 15.8 0.4 2 23 302 323 302 323 0.98
6 28 7.3e-07 0.0001 22.7 0.8 1 23 344 366 344 366 0.99
7 28 3.1e-06 0.00042 20.7 1.4 1 20 372 391 372 394 0.94
8 28 8.9e-05 0.012 16.1 2.3 1 23 400 423 400 423 0.97
9 28 0.0039 0.54 10.9 6.4 1 23 432 455 432 455 0.98
10 28 4.5e-07 6.2e-05 23.3 1.4 3 23 563 583 561 583 0.98
11 28 0.033 4.5 8.1 4.7 1 23 589 611 589 611 0.98
12 28 1.5e-05 0.002 18.6 3.1 1 23 617 639 617 639 0.99
13 28 4.5e-06 0.00062 20.2 0.4 2 23 644 665 643 665 0.98
14 28 0.00022 0.03 14.9 3.6 1 23 722 744 722 744 0.98
15 28 7.4e-07 0.0001 22.7 1.7 1 23 750 772 750 772 0.99
16 28 0.00015 0.021 15.4 2.4 2 23 779 800 778 800 0.96
17 28 0.00032 0.043 14.4 7.4 1 23 806 828 806 828 0.98
18 28 0.0087 1.2 9.9 0.3 1 23 1140 1163 1140 1163 0.92
19 28 0.082 11 6.8 2.1 2 23 1189 1210 1188 1210 0.96
20 28 1.4e-05 0.0019 18.7 1.9 1 23 1216 1238 1216 1238 0.98
21 28 0.00015 0.021 15.4 1.3 2 23 1247 1268 1246 1268 0.96
22 28 4.9e-08 6.7e-06 26.4 0.9 2 23 1336 1357 1335 1357 0.98
23 28 0.032 4.4 8.1 6.4 1 23 1363 1385 1363 1385 0.96
24 28 2e-05 0.0027 18.2 2.3 1 23 1391 1413 1391 1413 0.97
25 28 0.0019 0.26 11.9 2.7 1 23 1419 1441 1419 1441 0.98
26 28 5.7e-07 7.8e-05 23.0 0.6 2 23 1640 1661 1639 1661 0.97
27 28 0.0015 0.2 12.3 6.4 1 23 1667 1689 1667 1689 0.99
28 28 1.1e-06 0.00015 22.1 2.2 1 23 1695 1718 1695 1718 0.96

Sequence Information

Coding Sequence
ATGCATTACTACCTTCAAACGAGGAAATATAATGTTGAGCGAAAAATCATGTTGACAGCACAAACGTCAGAGACGATGTCTCTTGCCATTGATACTTTACCCCTCGGCCTTTTTATCGCCGATGACGGTCGAACATTACTTGTAACAGATCACGATGAATCAGCGTTGGAGTGGACAGCAGTGCCTGTGACATTGATCCAACAGTCCAACAGTTTGATAGCGCCGCCAGTGAAAATAGTAAATGGCAGTGACGGCGTAAATACAtcgTTGATTCAGCTGAATTTTGATCGCACAAGCGCTCCTGCTAGCAATCAGACTACAACAGTGGTTTTAAACCCAGAAAATGCTGCATTGTCCGTCAGCAATAACATTTCTGGGCCCCGTGTCTCGAAGAAAACGTTGGTTCAGGATCAATTGGTCGTTCCAgcagctaataaaattattttggagAATCCAAGCAATAATTCAAGCTCCAAGATCCCTGCTGCATCTGTGATTGCCAAAAGAAGTCCTGGTAGACCCCGAAAAGATGCTATTCGTCCACCTGATgcacaaaaaaaatgtgatatttgTGGTGAGACATTTCAAAGGGACGCTCAATTACGCAAACACATGGAAAGCCATGTTGACGAAAAACCCCATCGATGCCCCAAGTGTCCAGAGTCATTTAATATACCGATAAATTTCACGCTCCACATGGCGACGCATAATACAGGCGACCCAAAGTGTCCGGTTTGTGGTCGAAAATTTGCCAGAATGGCCAGCCTCAAGTCACATTTGCTCCTGCATGAAATGGAGGAACACCTGTTTTGTAAAGAATGTGAGGATGCATTTCCAACAAAagcTCAACTTGAATCACATTTAAGACTTCACGATGAAAAGTGGCTGACAGACGATGTTAGAAAGTGCAAGCTTTGCAATGAACAATTTACTCAGCCGGCCCTTTATCGCATTCACATCCGAGAACACTACAAGCTACGAACAAAGATATTGAAGCAGACGAAGAAAGGAATTATTCACAAGACTgtgtataaatgtaaaatatgtcTAAAAGTCTTTCAAAAACCAAGTCAATTGTTGCGACACattcgagtacacactggaGAAAAACCATATACAtgcaATATTTGTAATCGGTCATTTTCGCAAAAAAGTTCACTGCAAATTCACACATGGAAACACGCTGCAACGCGACCTTTTAGCTGTAATTATTGCAGTGcgaaattcaatcaaaaagGAAACTTACATTTACATATTCAACGAGTGCACAATCTGACAGAAGTAGGACTAATTTATTCGTGTCCTCACTGTTcgtgttttttcaaaagaatGCAAGGCTTGAGCACTCACATGAAGAAAATGCACTCTAATCGTGCAGAGGAAGCACGGTGTGACAGTTCAACAGAAACCGGcacaaatcaaaataattcaacaaagATCAATCTGAGTGCAAATAATCTTGTGGACTCGACTGCTTCCGAGTATCAGCCAAGTGATATCCTGCAACAGGCGTTGAATAAAAGTGGCGTAGTTGAAAAAGCCGTGCGACAAGATGTTGAAGCAAAACAAGCCGTAAAAAACAACGATGCCGAATTTGTTACAATTTTAGACAGAAGTTCCGATGGTAACTTAAGCCGATACATCACGATGAAGCACCGCAATGTGGGCGCAACAAAATGGTATGGATGCAATTACTGTCACAAGGAATTTAAGAAGCCATCCGATTTAATTCGACACATACGAGTTCACACTCAAGAAAAACCATTCAAGTGTTCGCAGTGCTATCGTTCGTTTGCTTTGAAGTCGACGTTGAAGTGTCATGAACGGATTCACGGTGGGCAGAAGTCTTATACATGTGGTATATGTGGGCAGAAGTTCACATGCTCCAGTAGCCTGAAAACTCACATAAGgaCACATCAGTCGCTAATTCAATGTCAAATCTGTGATAAGACGTTTGCTTCAGCCAGTATTTTAAAGAGTCACATGAAAACCCATGGAAAATCACCAAGATCAAAAATATCCGCTGACGCTGAAGCGCTAATTCCTCAAATAGTTCTCGAAGAGCCACTATTGATAAGTGATGCTGGAAATAAAATAAGCATTGCACAAGTTCAATCAAAACAAAATCACGTGCAGAGTAATAAAGAAGACGGTGCACGGCCGCACAAATGTTGGGTTTGTCCAGCGGCATTTCGAAAAATCAGTCATTTAAAGCAACATTATCGTCGTCACACCGGCGAACGACCGTACAAATGTCCCACTTGCGATAGGAGGTTCACTTCGAACAGTGTATTAAAATCACACTTGCAAACTCACGAGTCGGACAGGCCGTGGCACTGCAATATGTGCAGTGCTACGTTCTCTACGCAAAGCAGTATGAAAAGACATTTGGTTACGCACAGCAACAAAAGGCCATTCATGTGTCCTTACTGTCATAAAACATTCAAGACCACAGTTAACTGCAGAAAACATATGAAAATACATAAAACTGAGCTGGCACAACAGcAATTGGATAAACAAAAGGCCGAAACGGCAAACCTATCAGCAACAGCTAATAAAACCGATGTATTACCCACACTGCcagtgaatttaaatttatctgaaGACATTAcggataatttttcacaaaccATCACGACAGATTTCACTCAAGCATTTTCCGAacaattttcctcaatttccAACGTTAAGGGCATGAATCTTGTAGACAACAATTCAGAGACAAAAATTgtTAATTTGCCGGAGGTTGATAATTTACGTACATCGCAAACTCTACACGCCGATGAAACGGGCACTGTCAcaatatcaaattattctGGCGATCAAGTTCTCACGCCTGAAAGCATCCGAGAGATTGAAGAAACTCTAAATCAACAGCTCTTTCATCTTGGAATGAATCTTGGGCTGGGCAGTAATTTACCGCGATCAATGGGTGACTCAGACGTTGCTAATTTAGAATCACGCGAGCCTGCagtattgaatataatttatgataattcaaAAGAATTAGAACCAAGTGATGGAGCGACAATTAATCCCAATatgttttcaacaaattttgacACGTTTGACATGAGTCAAATAGCTCTACAGTCGGATAGTGAAATGGATATAggaataaattctttaaattccACGAGTATGGCGAGTATTTTGCCGAGATCGGCACAAGAAGAGCAGAGATTAATACCGGTAACAATTGGAAATAATCTCGATGATAATCAAGCGAAAGAAACGAAACATTTAGTCGTTGTTAGCTCACTTCCTGCCTACTCTGAGCTGACTAAACCcgttcaatcatttttaaagtatCCGAAAATAATTGCCAAGGCTGACACAACCGATGAAACTGatcgattaaatttaaatagtgAATCAAACGAGCCATTGCCTTCAATTTCTCCACAAAACGTACAATTTTCTTGCATCTAttgcagtaaaaattttcccggAGAGTATGAATTAAAAAGACATTTGTACGTTGCTCATTTGTCACTGAATCTTGATAAAACACTTGATAATCATGAGATAATGAGCAATgaattaaaagaagaaaataccCTGCAGTGCCACATGTGTTTTAAGAAAGAGTACGACGTTGACAGTTTGAAAGCACACCTTAAAACTCACTGCGGACCCAAGGAATTCCAGTGTCCCGAGtgtcaaatgaaattttgtacaaATGGTGGACTCAGTCGACACGTAAAAATGCACTTGATCAAGCAGCTTAACAGATGGAATTGCACGCAatgttcgaaaaaatttaccaacgAGGAGCAGTACAGCCTTCACATGAAGATCCACAATCCAATTGACTGGACGACGATTCCAATAGAGCCTGACAGCTCGCAGAAGGAAGATTCAACCCTGACCCAGTCGAATTTGTTAGATTCTATGATTGCAAAATCACCTCGACTGCCTGCAGACTCTGCCTCGATGACTGAGAGCCTCGAGTCACCTCCAAAACACTCTCAAGCAGCCCTGGAAAAGAAAAAGTACGATAATCAGTGTCAATATTGTCCGAAAACCTTTCGAAAGCCCAGCGATCTTGTGCGACATATCCGAACACACACGGGCGAACGTCCATACCAGTGCGAGCACTGTGATAAAAGTTTTGCGGTCAAGTGTACGCTGGATTGTCACCTAAAAGTCCACACGGgcaacgaaaaattttgttgcaaTGTTTGCAATCGATTGTTTGCCACAAAGGGAAGCCTCAAAGTGCACATGCGACTGCACACGGGCGTCAAACCCTTCACCTGTCAACTGTGCAACTTGCAATTTCGGACTTCAGGGCATCGAAAAGTTCATTTGGCTACGCACGATCGAGAGAATGAACGCGGTGATCCGCGACCACGTGGAAAAAAGAAGATTTCACCTTCTGAAACAGTGAGtgaggaaaaaacaaataaaacgaCGAAAAATGATGAGTCAATTGCGAATGAAGCGTCACAATTTACAAATTTAGAAACAATTACAATTGATACTTCGGAGATTTCGGATCAGTTGACTTTTAATGCTGATggaacaataataaataataatccagTGCTGTCAGTCAACGGAGGCAATCAATTCATGGAACATCTGCAGTTTCTTATCGACAATGGACTCGTCACGGTGCAGACAGATGAATCTTTGCTGGCGCCATTGAATACAGTTGATAATACAACTGTTGCTCAAGATCCCGTGTCGGAGAATAGTCTTTTAGCGCCGCAGGACACTACAGTTGCGTGCAACCCGACTGACAATTTGATGCCAGCTCAATTAAATGTTGAGGAGAATGTTAACCAGGCGCATTTATCTCTGGAAAATTGTCTAgaaattccaactaatcctgaGCCCAGTCAGCCTGATGTATTGCCCACTCGTCTGCCGGTGAAAACTGCCAGATTGCCGGCAAAAAATCAGGTGAAGGAATGTGATATTTGTGGAAAATCATTTGCAAAAGTATCCCAATTAGTGAGACACAGGCGAACTCATACTGGTGAGAAGCCGTTCAAGTGTTGTATATGTTCAAAGTCATTTGCGCAAAAATCTACTCGAGAAATTCATCACAATACACATATTGGCGATCGACCATTTGCCTGTCCGCATTGTGATTTTACGTTTACacaaaaatggaatttacAGACACATTTGAAACGTGTGCATCCGTTGAATGCACCTGGAGGCAAAAAATTACGACGAGGACAGCAGATTGTGAGcgcaaaaattattcaagatgATAATCTAAgtcagaataataaaattccgaATTTAGATGATTTATCGTTTGTCGAGctactaaaataa
Protein Sequence
MHYYLQTRKYNVERKIMLTAQTSETMSLAIDTLPLGLFIADDGRTLLVTDHDESALEWTAVPVTLIQQSNSLIAPPVKIVNGSDGVNTSLIQLNFDRTSAPASNQTTTVVLNPENAALSVSNNISGPRVSKKTLVQDQLVVPAANKIILENPSNNSSSKIPAASVIAKRSPGRPRKDAIRPPDAQKKCDICGETFQRDAQLRKHMESHVDEKPHRCPKCPESFNIPINFTLHMATHNTGDPKCPVCGRKFARMASLKSHLLLHEMEEHLFCKECEDAFPTKAQLESHLRLHDEKWLTDDVRKCKLCNEQFTQPALYRIHIREHYKLRTKILKQTKKGIIHKTVYKCKICLKVFQKPSQLLRHIRVHTGEKPYTCNICNRSFSQKSSLQIHTWKHAATRPFSCNYCSAKFNQKGNLHLHIQRVHNLTEVGLIYSCPHCSCFFKRMQGLSTHMKKMHSNRAEEARCDSSTETGTNQNNSTKINLSANNLVDSTASEYQPSDILQQALNKSGVVEKAVRQDVEAKQAVKNNDAEFVTILDRSSDGNLSRYITMKHRNVGATKWYGCNYCHKEFKKPSDLIRHIRVHTQEKPFKCSQCYRSFALKSTLKCHERIHGGQKSYTCGICGQKFTCSSSLKTHIRTHQSLIQCQICDKTFASASILKSHMKTHGKSPRSKISADAEALIPQIVLEEPLLISDAGNKISIAQVQSKQNHVQSNKEDGARPHKCWVCPAAFRKISHLKQHYRRHTGERPYKCPTCDRRFTSNSVLKSHLQTHESDRPWHCNMCSATFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTTVNCRKHMKIHKTELAQQQLDKQKAETANLSATANKTDVLPTLPVNLNLSEDITDNFSQTITTDFTQAFSEQFSSISNVKGMNLVDNNSETKIVNLPEVDNLRTSQTLHADETGTVTISNYSGDQVLTPESIREIEETLNQQLFHLGMNLGLGSNLPRSMGDSDVANLESREPAVLNIIYDNSKELEPSDGATINPNMFSTNFDTFDMSQIALQSDSEMDIGINSLNSTSMASILPRSAQEEQRLIPVTIGNNLDDNQAKETKHLVVVSSLPAYSELTKPVQSFLKYPKIIAKADTTDETDRLNLNSESNEPLPSISPQNVQFSCIYCSKNFPGEYELKRHLYVAHLSLNLDKTLDNHEIMSNELKEENTLQCHMCFKKEYDVDSLKAHLKTHCGPKEFQCPECQMKFCTNGGLSRHVKMHLIKQLNRWNCTQCSKKFTNEEQYSLHMKIHNPIDWTTIPIEPDSSQKEDSTLTQSNLLDSMIAKSPRLPADSASMTESLESPPKHSQAALEKKKYDNQCQYCPKTFRKPSDLVRHIRTHTGERPYQCEHCDKSFAVKCTLDCHLKVHTGNEKFCCNVCNRLFATKGSLKVHMRLHTGVKPFTCQLCNLQFRTSGHRKVHLATHDRENERGDPRPRGKKKISPSETVSEEKTNKTTKNDESIANEASQFTNLETITIDTSEISDQLTFNADGTIINNNPVLSVNGGNQFMEHLQFLIDNGLVTVQTDESLLAPLNTVDNTTVAQDPVSENSLLAPQDTTVACNPTDNLMPAQLNVEENVNQAHLSLENCLEIPTNPEPSQPDVLPTRLPVKTARLPAKNQVKECDICGKSFAKVSQLVRHRRTHTGEKPFKCCICSKSFAQKSTREIHHNTHIGDRPFACPHCDFTFTQKWNLQTHLKRVHPLNAPGGKKLRRGQQIVSAKIIQDDNLSQNNKIPNLDDLSFVELLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-