Mrus029980.1
Basic Information
- Insect
- Machimus rusticus
- Gene Symbol
- ush
- Assembly
- GCA_951509405.1
- Location
- OX608052.1:42664388-42670871[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0038 0.7 11.7 0.1 1 20 182 201 182 203 0.94 2 9 7.4e-05 0.014 17.0 0.4 1 23 241 263 241 263 0.98 3 9 0.024 4.4 9.2 0.9 2 21 287 306 287 307 0.92 4 9 0.079 15 7.5 3.2 2 21 630 649 629 650 0.93 5 9 0.013 2.5 9.9 0.0 3 20 688 705 686 707 0.92 6 9 1.1 2.1e+02 3.9 0.1 1 23 746 768 746 768 0.73 7 9 0.01 2 10.3 1.3 1 23 774 796 774 796 0.99 8 9 0.00014 0.025 16.2 0.6 1 23 838 861 838 861 0.96 9 9 0.29 54 5.7 0.4 2 20 959 977 958 979 0.92
Sequence Information
- Coding Sequence
- ATGCGAGGCAAAAAGCCCGGCGAGGAGCAAAAAAGGCGAAGTGATGCTTTGATGGCGATGGGGCACCACCAGCTAGGGCTGCTGTGCCGGGCCGGGGCCGTGCGAGACGCGACCGTCGCCGCGCCGCGCTGGACAGTCGCGGTACGCAAACCGCGGCCGCGGTCTGATAACAAGGATTTGTGCAACAATGATCTCGTCGAGGAAGCGGCTTCAACTGAAATAGATCTTTCAGAGCCATTTTCATCGGAATCTCTTCATGAAAACTCATCAAGTCCGCGGTCATCCTCGGATTTGGATTCGTCAACAAAACAATCTCCGAAGAAATGCAACATAGAAAATGAAAGTCCGGCGATACCGAAATTGAGACTAAACGTGTCGCTCGCGTCCGATCCTGCGCTAAAGCCAGATGCgaaggatttaaaaattttatcagaagATGTCCAAGACGAGAATGGTAAAAAAAGCAGTGGAGAAGAAAGCCAGTTATTTGGCCAGGGACAGATTCGAAGTCCAAGCGCTGATCTTTCTCATAGACTTAAAGTTTTCATGTGTCATCCTTGCGGAATTGGCTTTTCTTCTCTTTCTACTTTAGAAGCTCATCAAACGTATTATTGCTCACACAGgaaaGAGGCCGAAGAAGAAGTGACACAAACTAACGAGACATCCTGTGAGAGGAGTTCTTCAGAACCATCCGCGAAATCTATAAAAACTGGTAAACAGTACGCCTGCCCACAATGTTCATACAGTGCTGATAAGAAGGTCTCGCTTAACCGACACATGAGAATGCACCAGTCATCTCCCGCTCCCAGCTCGAATGCATCGAACGGCGAAGAGTCTTCTAGTCAACAAATTGATCGTTACTGTTCAGAGTGTGATATtcgtttttcaaatattaaaacttatcGAGCCCACAAGCAACATTACTGTAGTTCTAGAAGAACTGAGGGGCCAGTAACACCTAAATCTGAATTAAGAAAGAGCGGATCTGTGAGCCCACAAGAGAGGCCGAAGACTCCCACATTAGTGGCACCCCCTCAGCCTTTTTTAGCATTGCCTACAAATcctattttaataataccatATTCGTTGATAAGAGCGGCAAGCTTGCTTCCTGGACCATTGACATCCATCACGACTGGTATCTCGAACCCAGATACAACTTGTTTTGCATTTGAAAATGGCTCTTTACAACCATTGGCAACAGCTATAACGTCTCAGGGATTGCTAGAGTCTTCGTCTCGTGTGCAGCCTCAATGCAACCCTACAGTTCACTTACTTACGGAGAAAAATTCCAATCCACGATCCAATCACGGTCAGCCGGCCAAGGCGAGCAAAAAGGATGGTTCTAGTCGTGAAACAGCTCCACTGGATCTTTCAGTACGTAAGTCACCGATTCCCAGGAGCCGTTTTGAGGTATGCGCCTCCTCGAGTGACGAAAATAAACTCGATATAGAGGCAATGATGGAGGGAAAGGAGAACCTTTCAATTGAGAGCGGGAAAATAACTCCAGAACAAATTGTGTGCGCTCCATCGTTGCCGAACAGTCCGTCTATGAGTCCATCGCCAAAACGGCGCACGACGAGTCCTAGAGGAAACGTGGTGTCGATCTCGCCTGGCCCAGTTGCTATGGACCACATGTCGTCGCTGAGATCTATTTTGCCTACGGACGTGGCGTTAAAATTGTCCGAGTCGAATATAATTCCGCCTTTGATATCAAAGCAAAACATAGAGCTCGCTCTCAAGATGTCTTCATCCTCCGGCAAGAAGCCGGCGGATAATTCGAATGCCTTGCCCTCTCCGCTGCTTGCTTTGCCGTCAAATCCTATAAGCGTTGTTCCTCCCATTGCTAACGTACAGCCGCAAATGTACGTCAAGCAAGGAGTGTCGAAGTGCAAGGAGTGCAATATTGTTTTCTGCAAGTTCGAGAATTACTTAGCGCATAAGCAGCACTATTGTTCGGCGAGAAACCAGGAGGGCTCGGACACCAAAACAAGTACGCCACCAGCCACTGGAAATTCTTCGGACACGACTTCGCCCCCAATTGCTTATCACCAATTGATATGTGCTGCATGCGGCATTAAGTATACGTCCCTGGACAATTTGCGGGCGCATCAGACGTTCTATTGTCCCAAGGGCGGGGACTTGACACCGAAGATCCCACTGGGCAAAGAGAGGTGTtccaaatgtaaaattgtcCATGACATAACGCACCCATGCCCGGTAACGCAAGGATCCTACAAGTGTCCAGTTTGTGATGTTATAAGCCTAACCGCTGCAGACAGTCGGAAGCACTTGGAGACTCATGGGAGTGTTAAAGCGTTCCGCTGCTCTATATGTAGATATAAGGGCAATACTCTAAGAGGAATGAGGACACACATTAGGATGCATTTTGATAAGAAAACCTCCGACTTTAACGAGGAGAACTACATGTCCTGCATTTTGGAGGAAGATGGCGTAGAAATCGTCAGCTCGACTCCGCTTAGTCAGGAGCAACATAGTCAGCAACAGCTGTTTAATTGTGAGATCTGCAACTACTCGTCGTCTTATAAGGGGAATGTGATGAGGCATATGAAGCTTGTTCATCCTCAGGCTTCATCTTCACCTCCTTCCACGTCGCCCGATATTGGAGAAGCCAATTACATTTTAAGTGAGAATGGCGATGCTAAGCAAAGCAGAACAACCGAAaaTGCTGCCATAAAATCCGAACCCAGTGAGCTCAAGAGCAGCGATAAGGAGTTTCTTGGGGACGGCGTCCCGACCATCAAAATAGAGCCGGAGGACAAGCGAGATAGTGACGCCAACGTTTCAGCAGCTCTTTCCCGATCTTCACCACTTTCTGCAGAGGAAAACTCGCTCAAaacaacaaatcaaaaatattgcCAAGTGTGCGACATAAAGTTCAACTACATGAACACGTTCATCGCCCACAAGCAGTTCTACTGCAAGAGCAAGCGGAGCGAGACGGAAGCCGCGAGCTCGGCCCCGGTCCAGTCGCCCGTGCTGGGCAACAAGAACAAGGAGAACATGGAGACCGTGCTCTAA
- Protein Sequence
- MRGKKPGEEQKRRSDALMAMGHHQLGLLCRAGAVRDATVAAPRWTVAVRKPRPRSDNKDLCNNDLVEEAASTEIDLSEPFSSESLHENSSSPRSSSDLDSSTKQSPKKCNIENESPAIPKLRLNVSLASDPALKPDAKDLKILSEDVQDENGKKSSGEESQLFGQGQIRSPSADLSHRLKVFMCHPCGIGFSSLSTLEAHQTYYCSHRKEAEEEVTQTNETSCERSSSEPSAKSIKTGKQYACPQCSYSADKKVSLNRHMRMHQSSPAPSSNASNGEESSSQQIDRYCSECDIRFSNIKTYRAHKQHYCSSRRTEGPVTPKSELRKSGSVSPQERPKTPTLVAPPQPFLALPTNPILIIPYSLIRAASLLPGPLTSITTGISNPDTTCFAFENGSLQPLATAITSQGLLESSSRVQPQCNPTVHLLTEKNSNPRSNHGQPAKASKKDGSSRETAPLDLSVRKSPIPRSRFEVCASSSDENKLDIEAMMEGKENLSIESGKITPEQIVCAPSLPNSPSMSPSPKRRTTSPRGNVVSISPGPVAMDHMSSLRSILPTDVALKLSESNIIPPLISKQNIELALKMSSSSGKKPADNSNALPSPLLALPSNPISVVPPIANVQPQMYVKQGVSKCKECNIVFCKFENYLAHKQHYCSARNQEGSDTKTSTPPATGNSSDTTSPPIAYHQLICAACGIKYTSLDNLRAHQTFYCPKGGDLTPKIPLGKERCSKCKIVHDITHPCPVTQGSYKCPVCDVISLTAADSRKHLETHGSVKAFRCSICRYKGNTLRGMRTHIRMHFDKKTSDFNEENYMSCILEEDGVEIVSSTPLSQEQHSQQQLFNCEICNYSSSYKGNVMRHMKLVHPQASSSPPSTSPDIGEANYILSENGDAKQSRTTENAAIKSEPSELKSSDKEFLGDGVPTIKIEPEDKRDSDANVSAALSRSSPLSAEENSLKTTNQKYCQVCDIKFNYMNTFIAHKQFYCKSKRSETEAASSAPVQSPVLGNKNKENMETVL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00424944;
- 90% Identity
- iTF_01461493;
- 80% Identity
- -