Basic Information

Insect: Machimus rusticus
Gene Symbol: L
Assembly: GCA_951509405.1
Location: OX608049.1:28259397-28268325[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.33 62 5.5 5.7 1 23 120 142 120 142 0.98

2 17 1.8e-07 3.4e-05 25.3 3.1 1 23 148 170 148 170 0.99

3 17 1.5e-05 0.0028 19.2 0.2 1 23 176 198 176 198 0.98

4 17 0.47 87 5.1 0.1 2 23 255 278 254 278 0.86

5 17 0.011 2.1 10.2 0.2 2 23 299 321 298 321 0.95

6 17 0.077 14 7.6 0.5 1 23 410 432 410 432 0.95

7 17 0.00022 0.042 15.5 1.3 1 23 440 462 440 462 0.96

8 17 0.0029 0.54 12.0 0.2 1 23 470 494 470 494 0.87

9 17 0.039 7.2 8.5 1.3 1 23 529 552 529 552 0.98

10 17 0.0011 0.2 13.4 2.9 1 23 584 606 584 607 0.96

11 17 4.7 8.8e+02 1.9 0.6 1 23 741 765 741 765 0.83

12 17 0.00079 0.15 13.8 4.6 2 23 774 796 773 796 0.96

13 17 0.091 17 7.3 0.1 1 23 802 824 802 824 0.92

14 17 0.56 1e+02 4.8 0.3 2 23 832 853 831 853 0.96

15 17 1 1.9e+02 4.0 0.5 2 23 937 958 937 958 0.95

16 17 0.00075 0.14 13.9 0.1 1 23 968 990 968 990 0.98

17 17 0.1 19 7.1 0.3 1 23 997 1019 997 1019 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.33	62	5.5	5.7	1	23	120	142	120	142	0.98
2	17	1.8e-07	3.4e-05	25.3	3.1	1	23	148	170	148	170	0.99
3	17	1.5e-05	0.0028	19.2	0.2	1	23	176	198	176	198	0.98
4	17	0.47	87	5.1	0.1	2	23	255	278	254	278	0.86
5	17	0.011	2.1	10.2	0.2	2	23	299	321	298	321	0.95
6	17	0.077	14	7.6	0.5	1	23	410	432	410	432	0.95
7	17	0.00022	0.042	15.5	1.3	1	23	440	462	440	462	0.96
8	17	0.0029	0.54	12.0	0.2	1	23	470	494	470	494	0.87
9	17	0.039	7.2	8.5	1.3	1	23	529	552	529	552	0.98
10	17	0.0011	0.2	13.4	2.9	1	23	584	606	584	607	0.96
11	17	4.7	8.8e+02	1.9	0.6	1	23	741	765	741	765	0.83
12	17	0.00079	0.15	13.8	4.6	2	23	774	796	773	796	0.96
13	17	0.091	17	7.3	0.1	1	23	802	824	802	824	0.92
14	17	0.56	1e+02	4.8	0.3	2	23	832	853	831	853	0.96
15	17	1	1.9e+02	4.0	0.5	2	23	937	958	937	958	0.95
16	17	0.00075	0.14	13.9	0.1	1	23	968	990	968	990	0.98
17	17	0.1	19	7.1	0.3	1	23	997	1019	997	1019	0.96

Sequence Information

Coding Sequence: ATGGGGCACCTATTTATGCTTTGGCAGCTACTGTTTTTCGGCGGTCTCCCATTGTTGTCTTGCGTTTTGGGAAAACCCTGCGCTCCACCGAGGAGAAGGCCTTGGCCTCTTTTTATGGGTTGTCTTCGCGCGCCTTTGTTTCCAAGGCATAAAGAGTTTGTGCCGGAGCAGCCTCCACCTGCGATGAATACGAATGAGCCCGGAGCGCTGGAGCTGGATGCCCGGCCGAGTGCCTCAAGACACCGTCGAAGGAGCCCGGGGCGACTCGCTTTTTCCGAGGGCGGAATCCAAAGCACCCAATCgcaacaattaattttccttgcaTCGAAATTTCAGAGTCATGCCGAACATCTACCCTTTAAATGTGAATATTGCGCCCGCCTCTTCAAGCACAAGCGCTCCAGAGACCGTCACACGAAATTGCACACGGGGGACCGGCGCTACCGCTGCCCCCACTGCGAGGCGGCATTTTCCCGAAGCGATCACCTCAAGATCCACATGAAGACGCACGACAACCAGAAACCGTTCCAGTGCACGGTCTGCAACCGGGGCTACAACACGGCGGCGGCCCTCACCTCCCACATGCAGAACCACAAGAAGCAGGCGGCTCTTTTGGGTGGTGGGGCACATGCCCTGAATTTCAGCCCACGTTCGACGGGTAGCGGCTCGAGCAACAGCAGCTTTCACAAGCGGCGGTACGCGACCGCGGAGAACAGCCCCAGCCGCGGCGACTACCGCAAGCAGGTGCGCGGCGCGTTCATCTCGTGCGTCTACTGCACGAAGTCGGACTTCGCGTCGCTGGACCAGCTGAACGCGCACATCCAGGCGATGCACGAGAACGCAACGCCCAAAGAGGGCCACCACGCCCTGACCGGCCACTCGGTGTTCCAGCTCTCGTGCGAGTACTGCACCATGAAGTTCCCCAACATCCCCGCGATGTTCCAGCACATGCGGGCCACGCACATCGACCGGCTCGCGAGCCCCAACTCCTACTTCGAGCACTTCAACCGCCTGGCCGCGTCGGGCACGTTCAGTCCGCGGCTGGCCACCAACGTGCGCTTAGACGAAATGAAGGTAAAGACCGAGGAGCCTAGCCCCAAGCAGGAGCGTTCATCAGAAGCGGAAAAGGATGAGGAACAAGTTGGCCCCACCGACTTGAGTCAGCCCAAAAAACGATCGCAAACGCCACAGTCGCAAGGGGCGAGTTCAGTAGAGAAACCTGGCGCCTTCTTGTGCAACCAGTGCAACGCCGGACTGCCCGACTTCGAGACGTTTCGATCGCATCTGAAGACGCACATTAGCCAGGGAGTTACCAACTTTGTGTGCCACCACTGCGGATTGTCGCTTCGTGACCAGGCTGAATATGAACGGCACGTCGTGTCACACTTCTTGATCTCGAGCTCCGAATACGCCTGCGCCAGTAGCTGCAGCAAGGTCTTCCCGAAGCCAGACGACCTTCAGAAACATTTGTTCGAGAGCCACATCCAGGCCATGTTCAAGTGCTCCCTATGCTCAGACCTCTTTGAGTCCAAAGTGGCCATCCAGGTCCATTTTGCGTGCGCTCATTCAAACGAAAATAAGATTTTCAGGTGCTCCGCATGCATGGAGACATTCAGGGCGGAAAAGGATTTTACCACGCATATCCGAACTCGGCATGCAAGCACCGGATCCATTCAGTGCATGTTTTGCAGAGCAGTTTGCTCCTCTGAGCTGGAGATGCACTTCCATTTAGCAGCGCATGCAAGGCAATTTCGGTGCCCCTCATGTCCGGAAACGTTTCACGTGGAGTTCCTGCTGGATCGACACATGCAGACGCATCACGCGCAGAAGGATGGAAGCGCAGTGGCCCCAATCACCAATGCTTCGAATCAACTGTTCCAGGGGCAGTTCGCTAAGACCCccaataacaacaacaacgtCCTCGACTACCACTCATTTGTGGCGGCGAACAAGAGCCTCTTCCCTCTCCCCAGCAACAAGTTCTATAATCCGCTGCAGGTCGAAACGAGCTCTTTGAACTCCTCCAGCAAGCATCCGTCGTTGATGTATGGATTAGGGCAAAGATACTTCGACACCAACAAGACCCTCCTCGACATGTACAACTACCAGCAAGAGAAAAGTGGCCCCAACTACTTCGTGAGCCCCAGTGGGTTTGAGGGCACCAGGGGCCCAAAGCCACAACCGGAAGTGAAAACTCCCGACCGAACGCACAACAGTGGATTTAGTTGCGGCATTTGCGAGCGCAGCGACTTCCGCACCGAGGCTGAGGTCCACTCCCATCGCAAGATCGTCCACAATCTGAAGACGGGGGTGAGTCTCAGATGCGCCTACTGCAGCGGCAATTTCAAGTCCCGGAGTGAGCTGGAGCACCACATGAAAACCTGCCACAATTCGACGGGAAAGCACAAATGCTTGATTTGCGATGAAATCTTCCCGTCGCCGGCTATTCTGGCGGAGCACAAATTGCAGCACTCGAAAGTCGGACAGTCTGGGAAATGTTCGCACTGCTCGGCGGCTTTGAACGACGTCGCCGCGTTCAAATCTCACCTATCCGAGCACAATGTCGAGGGCCAGATTCCAGTGCAATGCATCTGCTGCCGACAGACCCTCAACTCGGACTTTGAGATTGGACTCCACGCCAAGTTCCACACAAAATCCTCTGGAACGCCTGAGAATCTTTGCGCTCTCTGTCTGGAAGCAATCCCACCTTCATCGGAAGCTCGAGTCTGCGAAAAATGTTGCCGCAAGCATAATCTGACCTCAAAATTTAACATGCGCTTCGAGTCCTCCCGCTCGTACGTGGAAAATAGGTGCAACCTCTGCAAGATGATCCTACCTCACGCCCAGCGGCTCCAAGAGCACCTCATCGAGCACACCTTCGTCGGGTGCGAGGAGCGCGGCTACTCGTGCTACATTTGCTCGGCCGTCTTCACCGTGCCGACGGGGCTGCTGAGCCACATGAACGAGCACGGCCCCAACGCACGGCCCTACGACTGCAACCTCTGCTCCGAGAAATACTTCTTCAGGGCCGAGCTGGACAACCACCTGATCGAGCACGAAAACCGTGTTAAGACTGACCTCAAGCACGAGACCCAGCAGGAGCAGCAGCCGAAAGAAGCAGCGGCTTCAGCCCAATCCGAAAAGGGGTCAGAACAGAAAGAGTCCAAGAAGGAGGCTGCTGAGGAGCCCCATCCAGAGGTCAAAACTGAGGTCGCTGAGAACGAGAAGGACGAGGACGAGGAGGAGTACATCGAAGTAGAAAAGATCGCGGAGGCTTCCGCCCCCGAGGTGGCCCAGAACCACCAGCACGATGACTAG
Protein Sequence: MGHLFMLWQLLFFGGLPLLSCVLGKPCAPPRRRPWPLFMGCLRAPLFPRHKEFVPEQPPPAMNTNEPGALELDARPSASRHRRRSPGRLAFSEGGIQSTQSQQLIFLASKFQSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGGGAHALNFSPRSTGSGSSNSSFHKRRYATAENSPSRGDYRKQVRGAFISCVYCTKSDFASLDQLNAHIQAMHENATPKEGHHALTGHSVFQLSCEYCTMKFPNIPAMFQHMRATHIDRLASPNSYFEHFNRLAASGTFSPRLATNVRLDEMKVKTEEPSPKQERSSEAEKDEEQVGPTDLSQPKKRSQTPQSQGASSVEKPGAFLCNQCNAGLPDFETFRSHLKTHISQGVTNFVCHHCGLSLRDQAEYERHVVSHFLISSSEYACASSCSKVFPKPDDLQKHLFESHIQAMFKCSLCSDLFESKVAIQVHFACAHSNENKIFRCSACMETFRAEKDFTTHIRTRHASTGSIQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHAQKDGSAVAPITNASNQLFQGQFAKTPNNNNNVLDYHSFVAANKSLFPLPSNKFYNPLQVETSSLNSSSKHPSLMYGLGQRYFDTNKTLLDMYNYQQEKSGPNYFVSPSGFEGTRGPKPQPEVKTPDRTHNSGFSCGICERSDFRTEAEVHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSAALNDVAAFKSHLSEHNVEGQIPVQCICCRQTLNSDFEIGLHAKFHTKSSGTPENLCALCLEAIPPSSEARVCEKCCRKHNLTSKFNMRFESSRSYVENRCNLCKMILPHAQRLQEHLIEHTFVGCEERGYSCYICSAVFTVPTGLLSHMNEHGPNARPYDCNLCSEKYFFRAELDNHLIEHENRVKTDLKHETQQEQQPKEAAASAQSEKGSEQKESKKEAAEEPHPEVKTEVAENEKDEDEEEYIEVEKIAEASAPEVAQNHQHDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00628637;
90% Identity: iTF_00718036;
80% Identity: -