Basic Information

Insect: Machimus rusticus
Gene Symbol: -
Assembly: GCA_951509405.1
Location: OX608051.1:31037843-31039860[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0029 0.54 12.0 2.4 1 23 238 260 238 260 0.97

2 10 2.3e-05 0.0044 18.6 2.0 1 23 265 287 265 287 0.99

3 10 4.6e-05 0.0086 17.7 1.2 1 23 293 316 293 316 0.96

4 10 0.00022 0.041 15.6 0.5 1 23 322 344 322 344 0.97

5 10 0.0001 0.019 16.6 2.0 1 23 350 372 350 372 0.98

6 10 0.063 12 7.8 0.3 1 23 394 416 394 416 0.85

7 10 0.0036 0.68 11.7 4.6 1 23 422 444 422 444 0.93

8 10 7.8e-06 0.0015 20.1 0.5 1 23 450 472 450 472 0.98

9 10 7.8e-07 0.00015 23.3 2.7 1 23 478 500 478 500 0.98

10 10 0.0005 0.093 14.4 7.2 1 23 506 528 506 528 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0029	0.54	12.0	2.4	1	23	238	260	238	260	0.97
2	10	2.3e-05	0.0044	18.6	2.0	1	23	265	287	265	287	0.99
3	10	4.6e-05	0.0086	17.7	1.2	1	23	293	316	293	316	0.96
4	10	0.00022	0.041	15.6	0.5	1	23	322	344	322	344	0.97
5	10	0.0001	0.019	16.6	2.0	1	23	350	372	350	372	0.98
6	10	0.063	12	7.8	0.3	1	23	394	416	394	416	0.85
7	10	0.0036	0.68	11.7	4.6	1	23	422	444	422	444	0.93
8	10	7.8e-06	0.0015	20.1	0.5	1	23	450	472	450	472	0.98
9	10	7.8e-07	0.00015	23.3	2.7	1	23	478	500	478	500	0.98
10	10	0.0005	0.093	14.4	7.2	1	23	506	528	506	528	0.98

Sequence Information

Coding Sequence: ATGTCAGCGGATATCAAAATATGTCGAGTTTGCGAAGCGACGCAAGATTTGGAGGTAATTTTCCACCAAGAAAGCTCAGATCtggttgaaaaattaatgctaTGTGCTGATGTCCAGGTTGATGCACACGACCAATTGCCTCAATTTATCTGCCTTAAATGCTCCGAGCGACTCAATTTGgcttatgaatttaaaatccaATGTGAGAGTACGGATGCAAAATTGAGGAGACGATTGCTTCGAAACGAATTTAAGAAATGCAAGGTTGAAATAGATGAGCCGATTGCAATCGTCGATACTGGCGAGGAATTGGACGAATTTTGTTTGGATGACTTTGATGATGTCGAGGAACTTATTGAAGTCGAAGGCGTCGAGTTCAACGAAGACGGGGAGGAAGTTCCTATTGAAAATACCCACTACGTAGAAGAGGTAGAGGAGAGTCATGATGGTCAAATGGAAATTTCAATTGAGGGAGAGTACGGAAAAGGGATTAGTCTGGATGGTTCTCATTCTAACGAAGGAGACGAAGATTTTCTAATTCTGGAAGAAGAGCCCTGCATCGAAGTAAAAGAAGAAAGTGGTTTAGAACATACCTTTGTAGTTGACGATGTTTCCAATACAGAAATGCTTGCTGAGACTAAGGAGGACGAAGAAAATGAATCGGTCgatataaaacagaaaaaggtAAAAAGTAATATTGTGGAGAAATTTTTTGCTTGCGACACTTGCGGCGCACACTTTAACACCTTTGTGGAATTTAATCAGCATAAAAAGTCGCACGGTGATAAGCGTTACCAATGTCCTGTCTGTACAAAAtggttttcaaagaaataccGCCTAAAGAACCACATGTTGACCCACGAAGGCTTAAAGACGTTTGCTTGTGAAATATGCGGAAATAAATATACCAACCAAGGCAATCTGGACAGACATGTAAGGCATTTTCATAAGAATGAACGCCCGTACATGTGTAATCAGTGTGGACTGAGTTTCTCTAGATCAAATATCCTTAAACTGCATTTAACCGTCCacataaaagaaagaaatttcgAATGCGATGTATGTAATAAAAGATTTAAGGCGGAGTATTACTTAAAACTACACAAGAAATCGCACATACCAATTGAGGAAAGACCTCAGACAATTCGGAAAACAAGGCAAGGAAAGAAGCCAAAAACTTTTGCCTGCTCATATTGTGGTAAAGTATTGGCAAGTAAAGCTGTTCACGATATCCACGTGCGTACTCATACCGGAGAAAAGCCTTTTGAATGCACCACTTGCCACAGAAGATTCGCTTTCAAACAGTCTTTGAAATCCCATGAATTTCTACATACCGGGGAAAAACCTTTCTCCTGCGAGCTTTGCGGACTCTCATTCCGGCAAGTGGGCCATTTAAAGGGCCATATGCTGGTTCATTCTGGtcttaaaaatcacaaatgcAAATATTGTGAGAAATCATTTGCTCTAAAGAGCAATTTGATAGTGCACCAACGACTTCATACTGGCGAAACTCCATACCATTGCCATTTGTgcgagaaaaaattttatgattccAATGGTCTGAAGCGGCACAAAAAGTCCCATTTGAAAGAACAAGCTGAGATGGAACTTAGCGAGCTTGTAAAAATAGAACCTATTGCTGAGTTCCTCGAGGAGAATAGTAAAGAGTACAGCGAAATTATTGAAATGCAAGCTAATGGAGAGATAAGGATAGTCACTTTAAGCGAAAACAAAAAGATTGCGCTGTGTCAGCAAGAGACTTCTTGA
Protein Sequence: MSADIKICRVCEATQDLEVIFHQESSDLVEKLMLCADVQVDAHDQLPQFICLKCSERLNLAYEFKIQCESTDAKLRRRLLRNEFKKCKVEIDEPIAIVDTGEELDEFCLDDFDDVEELIEVEGVEFNEDGEEVPIENTHYVEEVEESHDGQMEISIEGEYGKGISLDGSHSNEGDEDFLILEEEPCIEVKEESGLEHTFVVDDVSNTEMLAETKEDEENESVDIKQKKVKSNIVEKFFACDTCGAHFNTFVEFNQHKKSHGDKRYQCPVCTKWFSKKYRLKNHMLTHEGLKTFACEICGNKYTNQGNLDRHVRHFHKNERPYMCNQCGLSFSRSNILKLHLTVHIKERNFECDVCNKRFKAEYYLKLHKKSHIPIEERPQTIRKTRQGKKPKTFACSYCGKVLASKAVHDIHVRTHTGEKPFECTTCHRRFAFKQSLKSHEFLHTGEKPFSCELCGLSFRQVGHLKGHMLVHSGLKNHKCKYCEKSFALKSNLIVHQRLHTGETPYHCHLCEKKFYDSNGLKRHKKSHLKEQAEMELSELVKIEPIAEFLEENSKEYSEIIEMQANGEIRIVTLSENKKIALCQQETS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00718013; iTF_01184032; iTF_01461378; iTF_00936778;
90% Identity: iTF_00718013;
80% Identity: -