Basic Information

Insect: Machimus rusticus
Gene Symbol: -
Assembly: GCA_951509405.1
Location: OX608051.1:4840551-4844600[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 2.7e-07 5e-05 24.7 0.6 2 23 181 202 180 202 0.96

2 12 3.8e-07 7.1e-05 24.2 2.8 1 23 208 230 208 230 0.99

3 12 7.3e-08 1.4e-05 26.5 3.1 1 23 236 258 236 258 0.99

4 12 1.1e-06 0.00021 22.8 0.4 1 23 264 287 264 287 0.98

5 12 1.3e-05 0.0024 19.5 0.5 1 23 294 316 294 316 0.97

6 12 7.5e-07 0.00014 23.3 3.1 1 23 323 345 323 345 0.97

7 12 0.0034 0.63 11.8 3.2 1 23 351 373 351 373 0.98

8 12 0.00012 0.023 16.3 0.6 1 23 380 402 380 402 0.99

9 12 6.4e-05 0.012 17.2 2.2 1 23 410 432 410 432 0.98

10 12 5.4e-05 0.01 17.5 1.0 1 23 440 463 440 463 0.95

11 12 0.00025 0.046 15.4 0.5 3 23 473 494 472 494 0.96

12 12 0.0076 1.4 10.7 2.3 2 19 500 517 500 521 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	2.7e-07	5e-05	24.7	0.6	2	23	181	202	180	202	0.96
2	12	3.8e-07	7.1e-05	24.2	2.8	1	23	208	230	208	230	0.99
3	12	7.3e-08	1.4e-05	26.5	3.1	1	23	236	258	236	258	0.99
4	12	1.1e-06	0.00021	22.8	0.4	1	23	264	287	264	287	0.98
5	12	1.3e-05	0.0024	19.5	0.5	1	23	294	316	294	316	0.97
6	12	7.5e-07	0.00014	23.3	3.1	1	23	323	345	323	345	0.97
7	12	0.0034	0.63	11.8	3.2	1	23	351	373	351	373	0.98
8	12	0.00012	0.023	16.3	0.6	1	23	380	402	380	402	0.99
9	12	6.4e-05	0.012	17.2	2.2	1	23	410	432	410	432	0.98
10	12	5.4e-05	0.01	17.5	1.0	1	23	440	463	440	463	0.95
11	12	0.00025	0.046	15.4	0.5	3	23	473	494	472	494	0.96
12	12	0.0076	1.4	10.7	2.3	2	19	500	517	500	521	0.91

Sequence Information

Coding Sequence: ATGTGCCGGGTCTGCATGGACCCAAAGGGCGAAGTCGGCATTTTTGACGACGAAACATCCGACAAATTCCGCTTTCTAACCCTGCTAGATATTTCAGATAAGGATGATTTGCCATCGCATCTTTGTCTCGCTTGTTTCAGAAAGCTTAAAATAGCGTACGAGTTTAAAAATCAAGCAATAGCATCAGACACTCACCTACGaaactttataaattcaataaatacgAAATTTTCAGCTTTGGCTGAGACCCACAGAAAAGAGGCTTATACGAGTTTAGAGGAAATTAACGCCTTACTACTAGCCGGAGATACAGTGACCATacttaaaaatgatgaaagtATTCAAGAGAGTGAAGATCTTATAAATACAACTCAAATCGAGCTGCTTGAAGAAGGAGATACTGgtggaatatttgaaaatgattgTGAAAACGAAGATATCAACACCGACGATGAACAGATGGATCAGGATGAAGATTCAAAGGAGGATTCAACTGTGGAGGAACTGAAGGTCGAGATAACGCGGTATGAAGACTCACTGTCTTGTGCAGAATGTAATAAACGATTTTCAACCAAACCAAATCTGATGCGACATATTCTGACGCATACGAAGACAAGGCCATACAAGTGCACTATTTGCGGAAGCCATTTCACGCAGAACGGGTCCTTGAAGCAGCACATGATGACCCACACTGGGGAAAGGCCTTATAAGTGCAATGTTTGTCGAAAATCTTTTACGAGGAAGACTATGCTGAGCATCCACATGCGAACGCACACTGGGGAAAAGCCATACCAGTGCTCTGAATGCAATGTTTCATTCTCGTTGAGAGCGGGGTTAAAAAAACATATGAATACTGCGCATCGCAAATCCAATGAGGAATTTCCGTGCACTATTTGTGACAAAGTTCTACGATCGAAATATTCCCTCACAATGCACCTCAGTCTTCACACCGATGATGAACAAAAACACGAATGCCCGATCTGcttaaaaacgttttcaaataaatataacctGAAATACCACATTAAAAATCACGAGTCGGACGAGAAATACGTTTGCTTAATATGCGACAAATCGCTCAGTTGCAAATCTAAGCTCAAATATCATCTCAGCACTCACAACAAGGATAAAGAGGAGTTCAGATGCTCCGTTTGTGAGggaattttctcaaaaaaatttcaactacTCGCCCATTTACAAACGCACGAAAGCAAATCAAATAGCAATTTTTCATGCAGGAAATGTAAGAAAGAATTTACATTAAGagAAAACTTGTTAGAACACCTCCGAAATCATGTGGATAACACAGCCCCATTCTTCAGGTGTTCGAAGTGCGACATTGCATTTAATGTGAAGCGAAATTTAAAACTGCATCTGATCAACTTTCACAAGGAGCATGTAACCGACCTCAACAACTGCGATATCTGCGATATTACTTTTGTTTCTGTAACTCACTTGAATGAGCATATCGCTAAAAAGCATGACGTAGTTGATGAAAAATGCGATGAATGCGGTGAAAAGTTCACATCGAAGAGACTGTTTTTGGAGCACTGTATTCTTCACGATATTGTGGACATTAGAGAGGACAAACGATAA
Protein Sequence: MCRVCMDPKGEVGIFDDETSDKFRFLTLLDISDKDDLPSHLCLACFRKLKIAYEFKNQAIASDTHLRNFINSINTKFSALAETHRKEAYTSLEEINALLLAGDTVTILKNDESIQESEDLINTTQIELLEEGDTGGIFENDCENEDINTDDEQMDQDEDSKEDSTVEELKVEITRYEDSLSCAECNKRFSTKPNLMRHILTHTKTRPYKCTICGSHFTQNGSLKQHMMTHTGERPYKCNVCRKSFTRKTMLSIHMRTHTGEKPYQCSECNVSFSLRAGLKKHMNTAHRKSNEEFPCTICDKVLRSKYSLTMHLSLHTDDEQKHECPICLKTFSNKYNLKYHIKNHESDEKYVCLICDKSLSCKSKLKYHLSTHNKDKEEFRCSVCEGIFSKKFQLLAHLQTHESKSNSNFSCRKCKKEFTLRENLLEHLRNHVDNTAPFFRCSKCDIAFNVKRNLKLHLINFHKEHVTDLNNCDICDITFVSVTHLNEHIAKKHDVVDEKCDECGEKFTSKRLFLEHCILHDIVDIREDKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00936745; iTF_00717969;
90% Identity: iTF_00717969;
80% Identity: -