Basic Information

Insect: Machimus rusticus
Gene Symbol: zfy1
Assembly: GCA_951509405.1
Location: OX608054.1:20051092-20053390[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1.5 2.8e+02 3.5 0.1 2 20 190 208 189 210 0.91

2 12 8.8e-05 0.016 16.8 5.9 2 23 239 261 238 261 0.96

3 12 0.023 4.2 9.2 0.4 1 20 320 339 320 341 0.94

4 12 2.5e-07 4.7e-05 24.8 2.0 1 23 349 371 349 371 0.99

5 12 1.2e-05 0.0022 19.5 0.6 1 23 374 397 374 397 0.91

6 12 7.7e-07 0.00014 23.3 0.9 2 23 404 425 403 425 0.98

7 12 2.2e-07 4.1e-05 25.0 1.0 1 23 431 453 431 453 0.95

8 12 1.9e-06 0.00035 22.1 1.6 1 23 459 481 459 481 0.99

9 12 7.8e-07 0.00015 23.3 0.4 1 23 487 509 487 509 0.98

10 12 9.8e-05 0.018 16.7 0.5 1 23 515 537 515 537 0.98

11 12 5e-06 0.00093 20.7 3.1 1 23 543 565 543 565 0.99

12 12 2.7e-06 0.00051 21.6 0.4 1 23 571 593 571 593 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1.5	2.8e+02	3.5	0.1	2	20	190	208	189	210	0.91
2	12	8.8e-05	0.016	16.8	5.9	2	23	239	261	238	261	0.96
3	12	0.023	4.2	9.2	0.4	1	20	320	339	320	341	0.94
4	12	2.5e-07	4.7e-05	24.8	2.0	1	23	349	371	349	371	0.99
5	12	1.2e-05	0.0022	19.5	0.6	1	23	374	397	374	397	0.91
6	12	7.7e-07	0.00014	23.3	0.9	2	23	404	425	403	425	0.98
7	12	2.2e-07	4.1e-05	25.0	1.0	1	23	431	453	431	453	0.95
8	12	1.9e-06	0.00035	22.1	1.6	1	23	459	481	459	481	0.99
9	12	7.8e-07	0.00015	23.3	0.4	1	23	487	509	487	509	0.98
10	12	9.8e-05	0.018	16.7	0.5	1	23	515	537	515	537	0.98
11	12	5e-06	0.00093	20.7	3.1	1	23	543	565	543	565	0.99
12	12	2.7e-06	0.00051	21.6	0.4	1	23	571	593	571	593	0.98

Sequence Information

Coding Sequence: ATGTCACTGGAGTTTGATAAAATGTGCCGGACCTGCCTTTCGACCGGACCAGCGCTCCTATCGATTTTTGACAGCAAAATGCCGAACCAATTGGCCTCGATTGGGTCCCCATCGATTGCTGAGATGTTGAAGGCGATTACCTCAGTCGCTATAACCGACGAGGACGGTCTGCCTGGGAAGGTGTGTCTGGCGTGCATCAGCGAGATTAATCGGGCGTTTTCCTTCAAGATAAAGTGCGAAAATTCGGATTTCACCTTAAAACAGTATCTAATTCAGCAGATTAACCAATTCGGGGACAAGCAGAGCGAGACCAAATTCAAGGTCGAGCACGCGGAAAGTGACCGCGACCAGAAGGAGCTAATCGAACCAACCCAACTGGACCTCTCGCCGGAGGAGGAGGAAAGTCCTAAAGATTCTGGAGACGATGAGGAACATCTTTCATTGATGCTAACCGATCATGAGGATTTTGTCGAGGAGACACACTACGAAAATGGGACCGAGGAGCAGGTGGTCTACATGATTGAGCCCATAAACGGCCAGGTAATTGACGAGAAGGAGTTCGTCCTACAGTGTGCCGTCTGCAACGATAAATTCGACGATAGCGAGGCCTTCAGCTCTCACAGCAAAGACTGCTCCGGAGGCGCCGATACGGCTCCTGAGGACAAGCACTCCGGAGAGGAGAATTCAAAAGATAAGAGGAAAAAGACTCCGCTAAACTGCCCACACTGCCCTATGGACTTTGTCCATCAGAAAAATCTCACTAAGCACATAAAAAAGTGCCACGAGCGGGTCTTTGATTTAGAAGAGGAAAGCGCTGAAAAGGATGATGTTGAGCAATCACTGGAGGAATATGAAGAATTAACAAAAGATGGTCAAGAAACCGCTGAGGAAGTTAAGGACGTTATTGAGCAGGCGGAAGTTGTGAAGCACAAGCCAGCCGACCTGCCGGAGAGCCCCTATCGTTGCATGCAATGCGGAGCGGGCTTCGTTAAAGAAAAATCCCTCAACTACCACTTCAAGCTGAACAAATGCACGGAGAAGCAGTTCGAGTGCCCCGTTTGCCGGCGGGTCTTCATCACAAAGCGCAATTTGGTCCATCACATGAAGACCCACACAAACTTTAAGTGTGGAAAATGCGGCGAGGTCTTCTCCCGGAAGGAGAAGCTCAAGATGCACAACGACGTTGAACACAAGGGACTCATCAAGAATCAGTGCTCGCTCTGCGGGAAAGtttttaCGATGCTCTCGACGCTGAAAGATCACCTTCGGACCCACAGCGGTGAAAAGCCTTTTCTCTGCTCGATTTGTGGCAAGGGTTTCAGCCAAAGCACCAACTTGAAGCAGCACCTAATGAGGCACTCGAAGATCAAACCCTACAAATGCGACCGGTGCGAGCACTCGTTCGTTAGCAAAGGGGAGCTGAACGCCCACATCCGGAAGCACACCGGCGACCACCCGTTCGTCTGCACCACGTGCGGGGCGGGATTCACGACGTCCAGTTCGCTGGTGAAGCACCGGCGCATTCACACAGGAGAGAGGCCCTACGCCTGCGAGTTCTGCCCCATGAGATTCTCGGCTTTGGGAACACTGAAGAACCACCGCAGAACGCATACGGGGGAGCGCCCCTACGTCTGCAAATACTGCGACAGAGCTTTCGCCCAGAAAAGCGACTGCATGACCCACATGCGGACTCACACGGGGGAGCGTCCTTACATGTGCACTGTCTGCGGATTGTCCTTTTCCAAGTCCGGGGCGCTCAAGTCTCATCAGCAACTGCATCGCGCGGAGAAAACGAAAGATGAGGCCCCTGAAAATAATCCAGCGATTCCGGAAGACAACAGAAGCGCCTCCATGGATGTGGAGGTGTGCGTCCTCGGAGAAGTCTACCATGTGCCCGAAGAACTCAAGGGAGACATCCTCCAGGAGCAGCACACCGTGGGCTAG
Protein Sequence: MSLEFDKMCRTCLSTGPALLSIFDSKMPNQLASIGSPSIAEMLKAITSVAITDEDGLPGKVCLACISEINRAFSFKIKCENSDFTLKQYLIQQINQFGDKQSETKFKVEHAESDRDQKELIEPTQLDLSPEEEESPKDSGDDEEHLSLMLTDHEDFVEETHYENGTEEQVVYMIEPINGQVIDEKEFVLQCAVCNDKFDDSEAFSSHSKDCSGGADTAPEDKHSGEENSKDKRKKTPLNCPHCPMDFVHQKNLTKHIKKCHERVFDLEEESAEKDDVEQSLEEYEELTKDGQETAEEVKDVIEQAEVVKHKPADLPESPYRCMQCGAGFVKEKSLNYHFKLNKCTEKQFECPVCRRVFITKRNLVHHMKTHTNFKCGKCGEVFSRKEKLKMHNDVEHKGLIKNQCSLCGKVFTMLSTLKDHLRTHSGEKPFLCSICGKGFSQSTNLKQHLMRHSKIKPYKCDRCEHSFVSKGELNAHIRKHTGDHPFVCTTCGAGFTTSSSLVKHRRIHTGERPYACEFCPMRFSALGTLKNHRRTHTGERPYVCKYCDRAFAQKSDCMTHMRTHTGERPYMCTVCGLSFSKSGALKSHQQLHRAEKTKDEAPENNPAIPEDNRSASMDVEVCVLGEVYHVPEELKGDILQEQHTVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00717966;
90% Identity: iTF_01183988;
80% Identity: -