Mrus038189.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Machimus rusticus
Gene Symbol
-
Assembly
GCA_951509405.1
Location
OX608054.1:19178472-19181697[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.4e-05 0.0045 18.6 4.5 1 23 198 220 198 220 0.99
2 15 0.00063 0.12 14.1 1.2 1 23 226 248 226 248 0.98
3 15 1e-05 0.0019 19.8 4.1 1 23 254 276 254 276 0.98
4 15 3.5e-06 0.00065 21.2 0.6 1 23 282 304 282 304 0.97
5 15 4.3e-06 0.0008 20.9 0.9 1 23 313 335 313 335 0.98
6 15 0.00034 0.064 14.9 1.8 1 23 484 506 484 506 0.98
7 15 7.1e-06 0.0013 20.3 1.9 1 23 512 534 512 534 0.99
8 15 0.023 4.3 9.2 1.5 1 23 540 562 540 562 0.98
9 15 8.6e-07 0.00016 23.1 0.3 1 23 568 590 568 590 0.98
10 15 1.8e-06 0.00033 22.2 5.3 1 23 596 618 596 618 0.99
11 15 7.2e-07 0.00013 23.4 2.1 1 23 624 646 624 646 0.98
12 15 3.1e-05 0.0059 18.2 1.2 1 22 652 673 652 673 0.96
13 15 0.0006 0.11 14.2 1.9 1 23 685 707 685 707 0.98
14 15 0.0049 0.92 11.3 3.7 3 23 806 826 805 826 0.97
15 15 5.3e-05 0.01 17.5 2.4 3 23 849 870 847 870 0.96

Sequence Information

Coding Sequence
ATGATCAACATACTTCAACACCGGGAAAAGCTAGATTCTATGCTGATGCTTCACTGGGGATTGCGGgCCACAAAAGATGACTGTATCTGCAGAGGGTGCTGTGACGAAGTGCTGAATGCATggaatttaaatcaaaagtgCCAACATCCAAACCAGCACAACCCAAAAGTGCTGGTAAGTGAGGCGGCCTTTTTAAATCCCAAAACAAATTCTATTGATCCAACTGAAAGTTCAATCTTCCCAATGTACATTAAAGTTAAAGCGGAGCCCCAAAGTGAGAACGAGGTAGACACCAAACCCGATATTTTGAGGATGAACGTTGAGACCAAAAAGATAGGTGGACATGTAGAAAATACATCTGAAAGATTCGCCGGTGAGATtcctataaaaattgaaaatctggACACCCCTTTAGAAGAAAATGCTGAAAATAGCAGCGAGGATTACCCGCAGTATTTCAAGACGGAAATGCCATTTGATAGCGAAGACAGTGACGAAACAAACCAGAACCAGTTCGCGTTTGCGGAAAGCGCAATGTGTATTGTGAGATCGGCGAACCTTGAGACTAATCAAAGAACTGGAGAAAGACCCTACGAGTGCCCCCAttgctttaaaacttttattacttCGACAAGACTTAAGGAGCATAAAAGGACACACACCGGAGAAAGACCCTACGCCTGTAGCTCCTGTTCGAAAACTTACATTACTGCTGCCAGCCTTCATATTCACAGTCGCACTCATATGAAAGATAAGCCATTTGTCTGTTCTGAATGTGGAAAGAGTTGTACCACCTCTCAGTTGCTTAAATATCACAAGAGGACTCACACTGGGGAAAGACCCTACGCCTGCAGTTACTGCCCTAAATCTTACATCACCAACGGTCGCCTGCAAAGGCATATGTCCAGCCATATGAAGGAAAAACAGGACGGCCCCTTCGAGTGCCTCCAATGttccaaaaaattcaaaagcagTTGGGCTCTTAAGATTCACATTCGCATGCATACGCAAGAAACAAATGCATCCGACTCGACGCAAGGTTCCTACCAATccaacaaacaaaaacaagaagTACAGAGTGATGAAATTGACCCCGAAATAGGGGCGGCCCCGTCAATGGAAGTGAAAGAGAAACACGAAACCCAGGACAAAGAGGCAGAAGAcgactgtaaaattttaattgctgaATCTGGAACTCAGAAAATATCGAAAGAGTTTAGAGGTGATGAAAAAACAGAAGACGTACCTGAAACACAAAGCAGCACAATAGAGTTTCCTGGAAAGAAGGATGGAAAACACTACGAAAAACCCTCTAAGAAGGAGAACGACAACAATAAACGTAATTACAGTTCAGAATTGAATTTACAACCCGAACTAAAAAATGACGAAAATGTGTCAGAAGTTCTCACACAAAAACAGTCCACCCGAATGCATGCGAAGAAGAAATCTTTCTCGTGTTTAGAATGCGGAAAGAGTTTTCTCACAACGACAAAGCTCCAAATTCACAAAAGGACCCACACTGGAGAAAGACCTTACAAGTGTAACATTTGTCTGAAAACATTTGTTAGCTCATACAAGCTAACAGAACATAAGAGGATTCACGTTGGAGATAAACCTTACGAGTGCCGCTTCTGTTCCAAAACTTTCCTTAGGTCAACTGAAGTTCAAGGACATGAGCGAACTCACACGAAGGAGAAACCTTACATTTGCTCTGAATGCGGAAAGGGTTTTGTCACCTCGTCAGTTCTTAATCGCCACAAGAGGATCCACACAGGAGTAAAACCCTACGTCTGCAGTCACTGCTCTAAAACTTTCACCTCCAAATTCTATTTACAAACGCACATACGCTCTCATACGAAGGAAAATCTGTTCGAGTGTTCAGATTGTGGAAAGAGTTTTACAACTTCCAAAATGTTTCAGGATCACAAAATGACCCACACCGGAGAAAGACCCTACACTTGTAGTCACTGTTCTAAAAGTTACATTAATCGTAGTGGTTTGATAAATCACACGCGCAGTTATATGAAGGAAGCCCGTAAGAGAAAAGGTCCCTACGAGTGCCGCCAATGCTCTAAAGCCTTCAGCAACAGTTGCGCTTACAAGGTTCATGCTCTAATGCATTCTAAGCAGGCAAATTCATCCGATTCCAAACAAACGCCCAACCAGTCTAACACGCGTACGGGGACAAATTCAAaagATGAAATTCACCAAACTGAAATTGCAGTCGCTGCGAAGGAGGAAGGGGCAATGGATACCaacaaagcaaaattaaaaccgGAGATCAGCGAAAGCATGGAAGTGGATGATGTCGACTCAAGCCAGAATGCTGAAAATATCAGCGAAGATCCTCAGAATTGTTTTGAGAAGGAGAACTCAGTCgatatcgaaaataaaaatggagaaAGAGTCAACATTTGTAACTACTGCtttgaaacttttcattcTAATAGGGATTTCCGGACTCACGTGCGGAATCACAAAAAGGATAAGATTCCAGACTTTAAAAGTCATAAGAGAATACACATAAAAGAAAGAACATACGGTTGCAGCTACTGCTCTAAAACCTACATCAACAGTGGTCATATGCAAAAGCACATGCGAGAAAAACACAAAGTAGAAAAATCTTATAGATGGAAAGAAATCGACCCCTAG
Protein Sequence
MINILQHREKLDSMLMLHWGLRATKDDCICRGCCDEVLNAWNLNQKCQHPNQHNPKVLVSEAAFLNPKTNSIDPTESSIFPMYIKVKAEPQSENEVDTKPDILRMNVETKKIGGHVENTSERFAGEIPIKIENLDTPLEENAENSSEDYPQYFKTEMPFDSEDSDETNQNQFAFAESAMCIVRSANLETNQRTGERPYECPHCFKTFITSTRLKEHKRTHTGERPYACSSCSKTYITAASLHIHSRTHMKDKPFVCSECGKSCTTSQLLKYHKRTHTGERPYACSYCPKSYITNGRLQRHMSSHMKEKQDGPFECLQCSKKFKSSWALKIHIRMHTQETNASDSTQGSYQSNKQKQEVQSDEIDPEIGAAPSMEVKEKHETQDKEAEDDCKILIAESGTQKISKEFRGDEKTEDVPETQSSTIEFPGKKDGKHYEKPSKKENDNNKRNYSSELNLQPELKNDENVSEVLTQKQSTRMHAKKKSFSCLECGKSFLTTTKLQIHKRTHTGERPYKCNICLKTFVSSYKLTEHKRIHVGDKPYECRFCSKTFLRSTEVQGHERTHTKEKPYICSECGKGFVTSSVLNRHKRIHTGVKPYVCSHCSKTFTSKFYLQTHIRSHTKENLFECSDCGKSFTTSKMFQDHKMTHTGERPYTCSHCSKSYINRSGLINHTRSYMKEARKRKGPYECRQCSKAFSNSCAYKVHALMHSKQANSSDSKQTPNQSNTRTGTNSKDEIHQTEIAVAAKEEGAMDTNKAKLKPEISESMEVDDVDSSQNAENISEDPQNCFEKENSVDIENKNGERVNICNYCFETFHSNRDFRTHVRNHKKDKIPDFKSHKRIHIKERTYGCSYCSKTYINSGHMQKHMREKHKVEKSYRWKEIDP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-