Basic Information

Insect: Machimus rusticus
Gene Symbol: -
Assembly: GCA_951509405.1
Location: OX608049.1:29662673-29665511[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.022 4.2 9.2 0.4 5 23 240 258 238 258 0.95

2 13 0.15 29 6.6 5.6 3 21 268 286 268 288 0.95

3 13 0.00022 0.042 15.5 0.1 1 23 301 323 301 323 0.96

4 13 7.6e-05 0.014 17.0 1.1 3 23 331 351 329 351 0.97

5 13 2.1e-06 0.00039 21.9 0.5 1 23 357 379 357 379 0.98

6 13 5e-05 0.0094 17.6 3.9 1 23 388 410 388 410 0.98

7 13 1.1e-06 0.00021 22.8 0.2 2 23 417 438 416 438 0.97

8 13 1.1e-07 2.1e-05 25.9 2.5 1 23 444 466 444 466 0.98

9 13 2.8e-08 5.2e-06 27.8 2.0 1 23 472 494 472 494 0.99

10 13 7.1e-09 1.3e-06 29.7 1.2 1 23 500 522 500 522 0.99

11 13 2.2e-05 0.004 18.7 1.2 1 23 528 549 528 549 0.98

12 13 1e-05 0.0019 19.7 1.4 1 23 555 577 555 577 0.98

13 13 4.9e-05 0.0092 17.6 1.6 1 23 583 605 583 605 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.022	4.2	9.2	0.4	5	23	240	258	238	258	0.95
2	13	0.15	29	6.6	5.6	3	21	268	286	268	288	0.95
3	13	0.00022	0.042	15.5	0.1	1	23	301	323	301	323	0.96
4	13	7.6e-05	0.014	17.0	1.1	3	23	331	351	329	351	0.97
5	13	2.1e-06	0.00039	21.9	0.5	1	23	357	379	357	379	0.98
6	13	5e-05	0.0094	17.6	3.9	1	23	388	410	388	410	0.98
7	13	1.1e-06	0.00021	22.8	0.2	2	23	417	438	416	438	0.97
8	13	1.1e-07	2.1e-05	25.9	2.5	1	23	444	466	444	466	0.98
9	13	2.8e-08	5.2e-06	27.8	2.0	1	23	472	494	472	494	0.99
10	13	7.1e-09	1.3e-06	29.7	1.2	1	23	500	522	500	522	0.99
11	13	2.2e-05	0.004	18.7	1.2	1	23	528	549	528	549	0.98
12	13	1e-05	0.0019	19.7	1.4	1	23	555	577	555	577	0.98
13	13	4.9e-05	0.0092	17.6	1.6	1	23	583	605	583	605	0.98

Sequence Information

Coding Sequence: ATGAGTGCAATTGAAAAAACCCAATTCGAAATTATAAGCACCGACGACAGCTTGAAGGCCGCCTTCGAGCGTCCGCCGAGCGATGAGCATTTGCCGTTCGCACCCGCGATGGGCCATGGCGACGCCGAGGAAATCCTGGAGGCTGCCGACGCTCTGGACGCTGACCCCGGGGACCTGCGGCAGAAGCTGGAGCGGATCTGCAGGTGCTGCCTGGCCGAGTCCGACGAGTTGAAGTCGATTTTTGAGCCGGACGACTGCATCTCGTCGATGATTTTCTTGTTGACAAGTATTCAGttatctaAGGAGGATGGATTTCCTTCGAATGTCTGCATGGAATGCCTTTTACAACTCACACGAAGCATCAACTTTAAACAGCAAGTAGAAACAGCAGATATGACCCTCAAGAAGTTTGTAACTGAGGGATATTTCCAAGGAATGGTTTTACAGAAAGTAGACATAGAGCAATTGGCAAAGCGGCTgTCAGAGGACAATGAGTTCGATTTTATTAGCGTTGGAAATGACTTAGATATATCTGATACTGAACCGATGAGCAGCGTAAATGATTATGCAGTAGAAATCACGAAAATCGATGAGAGTAATATTCCTGAAAGTAGTTACTGCAATCAAACTtctgaaataagtaaaaacaaattagttCGTCAAGATAAGAAGCGAGGCAAGACGAAAAAGAATAAATGGAAATCAATACTCTGCATACTATGCGACAAGAATTTTTTAGATCCTAAAGATTATATGAGTCACATGAAAACGCATCCTGAAGGAGAGGCTCTTTTCTGTTGGTGCACCGTCTGCAACCGCAGTTTTAAAGATCACAACTCTATGGAATACCATTACCGTTGTCATGAAAACAAAACTGAAATGAACGAAactgaaaaactatttaaatgtAAGGACTGCGATCAAAGTTTTGCGGTTGAGGCTGATTTATATATCCACGGATCAGTTCATGAAACAAgcgataaaattatttgccgaaaatgtttaaaagaatTTCCAAGTGAACGTAAATTGAAACGACACATTCGCACGCACTTTGAGGATAAACCATATAAGTGCGAATTGTGCGGGAAAGGTTTCCCTGAAAAGGGATCGCTAACCAGACACTTTCGTCTTCATACGGGAGAAAAGCGAGAAAGGAAGCACGTATGCAATACCTGCGGGAAGAGTTACTTTGATGCCCATTCTCTTTCAGTTCATAAACGCACCCACACTGGAGAGAAGCCGTGGGTGTGCAAGGAATGTGGTAAAGGTTTTATTGATTCCAGACTTCTAAATTCCCACCTAAAGACtcataaagaagaaaaaatgtatGCTTGCGACAGGTGCGGTAAAAGATTTACACATCAAAGCACGCTAACGACTCATATACGAGTGCATACTGGCGAAAAACCTTACGTCTGCTATATTTGCCACAAGTCGTTTATTCAATCATCGAATCTCAACTTGCACATGCGGGTTCATTCCGGAGAGAAACCTtatcaatgcaaaatttgttcCAGATCATTTGCCAGCTCCTCGACTTTGACGGCACACATGCGAACTCATACTGGAGAAAAGCCATACACTTGTCCGCAATGCGATAAAACGTTTGCTCGCCACGATTTAAGTGCGCATATACGTTCCCATACTGGTGAAAAACCATACACGTGTGGCCTATGTTCCCGAAAATTCACAACTTCTGGACAACTAAACCAGCACAAACGGGCGCACATAACTGAGAAATCTTTTGTCTGCAAAATCTGCAACAAAAGTTTGTTGACagcaaattatttgaaaaagcaTATGAAGACCCACACTCATCCTGAAATTGAAGATCAAACTTTTCAAATGGAGAAGCTCAATGATCTACTTGCAGCTGTCGTCGATAGTAATTGA
Protein Sequence: MSAIEKTQFEIISTDDSLKAAFERPPSDEHLPFAPAMGHGDAEEILEAADALDADPGDLRQKLERICRCCLAESDELKSIFEPDDCISSMIFLLTSIQLSKEDGFPSNVCMECLLQLTRSINFKQQVETADMTLKKFVTEGYFQGMVLQKVDIEQLAKRLSEDNEFDFISVGNDLDISDTEPMSSVNDYAVEITKIDESNIPESSYCNQTSEISKNKLVRQDKKRGKTKKNKWKSILCILCDKNFLDPKDYMSHMKTHPEGEALFCWCTVCNRSFKDHNSMEYHYRCHENKTEMNETEKLFKCKDCDQSFAVEADLYIHGSVHETSDKIICRKCLKEFPSERKLKRHIRTHFEDKPYKCELCGKGFPEKGSLTRHFRLHTGEKRERKHVCNTCGKSYFDAHSLSVHKRTHTGEKPWVCKECGKGFIDSRLLNSHLKTHKEEKMYACDRCGKRFTHQSTLTTHIRVHTGEKPYVCYICHKSFIQSSNLNLHMRVHSGEKPYQCKICSRSFASSSTLTAHMRTHTGEKPYTCPQCDKTFARHDLSAHIRSHTGEKPYTCGLCSRKFTTSGQLNQHKRAHITEKSFVCKICNKSLLTANYLKKHMKTHTHPEIEDQTFQMEKLNDLLAAVVDSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00628562;
90% Identity: iTF_00717960;
80% Identity: -