Mrus025038.1
Basic Information
- Insect
- Machimus rusticus
- Gene Symbol
- ZNF236
- Assembly
- GCA_951509405.1
- Location
- OX608052.1:13165252-13169704[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.00016 0.031 16.0 3.3 2 23 111 133 110 134 0.94 2 20 0.00011 0.02 16.6 0.7 1 23 139 161 139 161 0.98 3 20 0.00021 0.039 15.6 0.1 2 23 167 188 167 188 0.97 4 20 0.016 3 9.7 0.4 1 23 194 217 194 217 0.97 5 20 4.2e-05 0.0078 17.8 0.2 1 23 244 266 244 266 0.94 6 20 0.00011 0.022 16.4 0.8 1 23 272 294 272 294 0.95 7 20 9.8e-07 0.00018 23.0 0.1 1 23 300 323 300 323 0.97 8 20 0.038 7.1 8.5 4.3 1 23 333 356 333 356 0.92 9 20 0.00013 0.024 16.3 0.2 2 23 458 479 457 479 0.97 10 20 0.00037 0.069 14.8 0.4 2 23 486 507 485 507 0.97 11 20 0.0017 0.31 12.8 0.6 1 23 518 540 518 540 0.98 12 20 6.1e-06 0.0011 20.5 1.2 1 23 546 568 546 568 0.96 13 20 0.00019 0.036 15.7 3.3 1 19 603 621 603 625 0.96 14 20 0.00023 0.043 15.5 1.9 1 23 631 653 631 653 0.96 15 20 7.7e-05 0.014 17.0 4.2 3 23 661 681 660 681 0.96 16 20 0.00019 0.036 15.8 6.0 1 23 687 710 687 710 0.97 17 20 1.6e-06 0.0003 22.3 1.4 1 23 1230 1252 1230 1252 0.97 18 20 0.0016 0.3 12.9 5.0 1 23 1258 1280 1258 1280 0.96 19 20 0.00029 0.055 15.2 1.0 1 23 1287 1309 1287 1309 0.98 20 20 7.8e-07 0.00015 23.3 1.7 1 23 1315 1337 1315 1337 0.99
Sequence Information
- Coding Sequence
- ATGAGCTCGAATGAAGAAACGTTCGGTGAAATTGGAGTTGGAGAGAGCTACACAAAAtctttgtttacatttaaCGAGGCCGACACGGACTTCTTGAGCACAAATGATTTCGTAGCTCTGGACCTAGACGGGGTGGTGGACTCCTTCAAATCGGCCGCAGCACAGTCGGAGTTTGCCAGCAATGAAGGTGTCGTCCAGCTCCAAGATCTGGTTTCAGAAAACCAAGAGGAGGAGACAGCTCGAGATGAAGATAATGTCACTGATCATCCAACtaaagttagaaaaaaaaggaagaaacgGACTCCACAAAGCCTCGAACCAAGATCACTTCGCTGTGATCTCTGCGATGAGACTTTCAGCCATTCCAGCGAGCTGAAGTACCACAGGGCCTCCACGCACCACTTGGCTAAGCTCTACCGGTGCGAAGAGTGCTCAAAGGGgttcaatttcgaaaaaaatctGTTCCTTCACATTGCTTCCCACAGTACCACACCCGCAGTATGTCCAGAATGTGGTAGGATGTTTCAGAGACTCTCCAGTTTCGTGGGGCACCTTGAAACCCACGCAGAAAACGACAACTTCAAGTGTCAGGCGTGTGACGAAGAGTTCGAGTTTGAGGAGTACTACGAGAGGCACCTGGAAAAGGATCACCGAGGTGGAGAAATGATGGCTGCTTTGCTCGTTAAAAAGAGGAATTCGAGAGACATTAATGTGGGCTACAAAGGAAAGTTTGTTTGCAAATCTTGCGGAAAGCGATTTCCAAAACCTAGTCTTCTTCTTCGGCATGAAATAGCTCACGCTAAAGTGAAGCCGTTTGCTTGTCTCGAGTGCAATAAAAGATTTAGCCAGAAAGCATCTCTAGACCGCCACAGTATGCTCCACAGTGGCATCAAGCCCTATGACTGTCCTGAGTGCGGAATGGGCTTTTCCCAACGTACCAACTTAATAACTCACATAAAACGAGTACACACAACTAACGAAAACGCAGAAGGGCAATTTCCGTGCAATAGTTGCTCCTGTGTTTTTAGTAAACTTAAAAGTCTGACCCGCCATAAAACACTGAAGCATTCAAGCAAgactgaaaacaaaaaaaccgaGTTGAGCTTTACGGAGATTCTCGAGCATATCATGAGTTTGCATGACCAAAATATAAGTCAAACCGCTTCCTTCAGCGACCAGGTCACTATGCCTGTGGGAGATGGAGATCGAATTGCTTCTAAACAAGTATCAGAGGTCCAGCAGCCTGTTCCAGAATGTCCTCCTGGTCCTGTAAAAGAGCAGTTCGTTAACGTCGTGGATCGGTTGTACCCGACTAAGGAAAGGGTTAATCGAATAGTAAAGGAAATTAACATTGATGGTATTAAGTGGCTCGAGTGCCCCTACTGTCCAAAAAGGTTTCAGATGCCCTTTGACATTGTTAGGCATTTACGCACACACACTAAAGAAAAACCTTGGAAATGTGAATATTGTGGTCGAAAGTTCGCGTTAAAAAATACCATGGAATTACATCTAAAAGTACACAGGAAGAAACCGAATGAAATTACTAAACTTTACAACTGCACTTATTGCCAAATGTCGTTTGATTCGATCAGAAGTTTGGACATGCACGTACGGATTCACAGCAATTACAAACCTTACGCTTGTTCAATATGCtcaaaaactttcaaaagtAACGATAATTTGAGACTGCACAAAACCATCCATGAACCAAAGGACCCAGACGACGAAAACATAAAACGCCAGCTTCTTCCTCCCATAATTCAAAATCCAGAAGAAAAACCGGAAAAGGATCAAAGCATCCGAATTTACCAATGTGAGAAATGCGGCCAAAGATTCAAAAAGTCCTCACATCTAGCGCAACATGATTTTAGTCACCTTAGCTTGAAGGCTTTTCAGTGCGAAATATGCAATAAatatTTCTCTACAAAGAGTTCCCTAggatttcatcaaaaaatcCATTTGGGCCACAAGACTGCGCCTTGCGAAGTGTGCCATAAACAATTCTGTAGGAATAGCGATTTAAAGCGGCACAAAGCAGTACACAgcaattttcgcaatttcatGTGTCCGTATTGCAAAAAGACGTTCAAAAGAAAGAGTAGTTGCAAACAGCATATTACAACACTTCATTTGAGAGATGTGGTTACAACAGAAGAAGTAGAAAATGTCGCATCGGTTTCAGATAATGATAACAATATATCTGATGTTAATGAGGATAGTCGTGCAGAACCACACGAACATCAGGTTGACCAAGATCCGACTCAAATAGTATTTAATATGGTTCCCATTAACGTCCcatctaatttaaatcaaagaaatcaGCTAGATATGAATCTCAACTTTACATCTGATTTAAATCAAAGTAACCAACAAGACGCGATTTTTCCTATTccacttaatttaaatcaaacgaATGAATCAGAaccgatttttctttttccaccTGACTTGAATCAATCAGAAGCAACCGTTCCAGCAGTTCTTGATCCAAACTTAAATCAACCAGATGCAGACTTTTGTATTTCACCCGAAATAAATCAATCAGAGACCGCCTTTCGGGTTCCATCAAATTTGAATCAAACGAATCGACCAAAGGTAACTTTTTCTAATTCAGCTGATTTGAATCAAGCCAATCAAATTACGATGACCCTACTGCCCGCTCCTCATGATTCAAAtcaaatgaatgaaataaatcgaCCAGAGTTGATCTTTCAATCCGTTCAATCCAATTTAAAACCGATTCAACCAGAAGCTGTCCTATCTTTCCCATCtgacttaaatttaatgcatCAAACAGAAACGAACCTTTCTATTCCACCCGACCTAAATCAAATGGATCATCCAGAAATAGTGCCAAGTACTCAAAACACACCTAGTGATTTTGCTTCACCTCGCATAATTTTTCTGCTTCAGCCAAACCAACAAAATTCTGTGCAACAGAAGGAGAATTTAATTGTTGTCGATCTGagacaaattttgaataaaaactttttacccCCCAAAACTTTTGATCAAGCACAGAAAACAAATCAGCCAGAGACTGATGTCCTTTCAGAAGCTGTTCcgcagaaaattgaagaactTCCAGTAGGTGCTTCacaaacatttgaaattcttCCAGAAGCTGCTCCGCAAGAAATTCAATTCCTTCCAGCAGCTGCTTCGCAAGAACTAGAAACGTTTCAAGCAGCTGTTTCAAATGGAGTTGAAACATTTCAAGCGGATGCTTCGAAAGAAATTGAGATGCTTCCAGCAACTGCTTCACaggaaattcaatttcttccaTCAACTGCTTCggaagaaattcaatttctccCAGTAGAAGCTTCGCAAGATATTGGAAGATTTTCAGCAGTCTCTTCacaagaaattcaaattctcCCATTAACTGCTTCACAGAAAATTGAAACTCCAGCAGCTGCTTTgcaaaaaactgaaataattcCCCCACAGCCAAAGCCAACACAGCCCGAATTTATAAGTATAAGCGACTTACCAAATTATAGCAAAAATTTAGCTAAAAACATAGTCGTCGTATCTCACGAAAAAAATCCTGATAGTTGCGACAACCTACCTGAAGCAGTTTTAAATGATTCTGAGACGCAGGAAGAAGAGTTTCTTATTCATGAAGCAGGAGCTAAGTTAGGAGAGCTGATAATGACAAAAGCCCCTAAAGCGAAGCCTCCACACCCCTGCTCAATGTGCAAAAAGGTTTTCCAGAAGCCGAGTGATTTAGTTAGACACATCCGAACACACACTAAGGAGAGACCTTTTCAGTGTCACACTTGCTCAAAGACGTTCAGCTTAAAGTCCACTCTGGACAATCACAAGTTTATTCATGATAAGGACAGGCCCAGTTTTATATGCCATGTCTGCGGGAAGAATTATGCTGCTAAAAATGTTCTTCGCACTCATTTGCGGATGCACACCGGGGAGAGGCCGTTTAAGTGTGATATTTGCCCGAAAACCTTCAGGACGTCCGGACATAGAACGGCTCATATTCGAGTACATGCAAAAATTGAAGCTACGAGGAAGAAAAAGAAGACTAAAGTGTAA
- Protein Sequence
- MSSNEETFGEIGVGESYTKSLFTFNEADTDFLSTNDFVALDLDGVVDSFKSAAAQSEFASNEGVVQLQDLVSENQEEETARDEDNVTDHPTKVRKKRKKRTPQSLEPRSLRCDLCDETFSHSSELKYHRASTHHLAKLYRCEECSKGFNFEKNLFLHIASHSTTPAVCPECGRMFQRLSSFVGHLETHAENDNFKCQACDEEFEFEEYYERHLEKDHRGGEMMAALLVKKRNSRDINVGYKGKFVCKSCGKRFPKPSLLLRHEIAHAKVKPFACLECNKRFSQKASLDRHSMLHSGIKPYDCPECGMGFSQRTNLITHIKRVHTTNENAEGQFPCNSCSCVFSKLKSLTRHKTLKHSSKTENKKTELSFTEILEHIMSLHDQNISQTASFSDQVTMPVGDGDRIASKQVSEVQQPVPECPPGPVKEQFVNVVDRLYPTKERVNRIVKEINIDGIKWLECPYCPKRFQMPFDIVRHLRTHTKEKPWKCEYCGRKFALKNTMELHLKVHRKKPNEITKLYNCTYCQMSFDSIRSLDMHVRIHSNYKPYACSICSKTFKSNDNLRLHKTIHEPKDPDDENIKRQLLPPIIQNPEEKPEKDQSIRIYQCEKCGQRFKKSSHLAQHDFSHLSLKAFQCEICNKYFSTKSSLGFHQKIHLGHKTAPCEVCHKQFCRNSDLKRHKAVHSNFRNFMCPYCKKTFKRKSSCKQHITTLHLRDVVTTEEVENVASVSDNDNNISDVNEDSRAEPHEHQVDQDPTQIVFNMVPINVPSNLNQRNQLDMNLNFTSDLNQSNQQDAIFPIPLNLNQTNESEPIFLFPPDLNQSEATVPAVLDPNLNQPDADFCISPEINQSETAFRVPSNLNQTNRPKVTFSNSADLNQANQITMTLLPAPHDSNQMNEINRPELIFQSVQSNLKPIQPEAVLSFPSDLNLMHQTETNLSIPPDLNQMDHPEIVPSTQNTPSDFASPRIIFLLQPNQQNSVQQKENLIVVDLRQILNKNFLPPKTFDQAQKTNQPETDVLSEAVPQKIEELPVGASQTFEILPEAAPQEIQFLPAAASQELETFQAAVSNGVETFQADASKEIEMLPATASQEIQFLPSTASEEIQFLPVEASQDIGRFSAVSSQEIQILPLTASQKIETPAAALQKTEIIPPQPKPTQPEFISISDLPNYSKNLAKNIVVVSHEKNPDSCDNLPEAVLNDSETQEEEFLIHEAGAKLGELIMTKAPKAKPPHPCSMCKKVFQKPSDLVRHIRTHTKERPFQCHTCSKTFSLKSTLDNHKFIHDKDRPSFICHVCGKNYAAKNVLRTHLRMHTGERPFKCDICPKTFRTSGHRTAHIRVHAKIEATRKKKKTKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00936741; iTF_00717956; iTF_01461327;
- 90% Identity
- -
- 80% Identity
- -