Mrus020523.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Machimus rusticus
Gene Symbol
-
Assembly
GCA_951509405.1
Location
OX608051.1:29825208-29833712[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 41 1.1e-06 0.0002 22.9 0.6 1 23 55 77 55 77 0.97
2 41 2.3e-05 0.0043 18.6 2.4 1 23 83 105 83 105 0.97
3 41 5.6e-05 0.01 17.4 2.2 1 23 111 133 111 133 0.98
4 41 0.00017 0.032 15.9 0.9 1 23 139 161 139 161 0.97
5 41 1.4e-05 0.0027 19.3 0.1 1 23 167 189 167 189 0.97
6 41 3.9e-05 0.0072 17.9 2.1 1 23 195 217 195 217 0.98
7 41 6.2e-07 0.00012 23.6 1.4 1 23 223 245 223 245 0.98
8 41 5.8e-06 0.0011 20.5 0.7 1 23 251 273 251 273 0.97
9 41 0.0033 0.62 11.8 0.2 2 17 280 295 279 296 0.92
10 41 0.15 28 6.6 8.0 1 23 307 329 307 329 0.96
11 41 0.004 0.74 11.6 0.8 1 17 335 351 335 352 0.94
12 41 0.0026 0.49 12.2 4.2 1 23 363 386 363 386 0.97
13 41 1.9 3.6e+02 3.1 0.1 5 17 540 552 538 553 0.89
14 41 0.0057 1.1 11.1 3.8 1 23 564 587 564 587 0.97
15 41 6.2e-07 0.00012 23.6 0.5 1 23 768 790 768 790 0.97
16 41 3.9e-05 0.0072 17.9 2.1 1 23 796 818 796 818 0.98
17 41 0.01 1.9 10.3 1.2 3 23 826 846 824 846 0.98
18 41 1.6e-06 0.00031 22.2 0.2 1 23 852 874 852 874 0.97
19 41 1.2e-05 0.0023 19.5 0.3 1 23 880 902 880 902 0.97
20 41 3.9e-05 0.0072 17.9 2.1 1 23 908 930 908 930 0.98
21 41 6.6e-06 0.0012 20.3 0.8 3 23 938 958 936 958 0.98
22 41 0.001 0.19 13.5 1.9 1 23 964 986 964 986 0.96
23 41 0.0081 1.5 10.6 0.2 2 17 993 1008 992 1009 0.90
24 41 0.049 9.1 8.2 7.5 1 23 1020 1042 1020 1042 0.96
25 41 0.004 0.74 11.6 0.8 1 17 1048 1064 1048 1065 0.94
26 41 0.0026 0.49 12.2 4.2 1 23 1076 1099 1076 1099 0.97
27 41 2.1 3.9e+02 3.0 0.1 5 17 1250 1262 1249 1263 0.89
28 41 0.017 3.1 9.6 3.8 1 23 1274 1297 1274 1297 0.96
29 41 4.4e-08 8.2e-06 27.2 0.7 1 23 1478 1500 1478 1500 0.98
30 41 0.00015 0.028 16.1 3.3 1 23 1506 1528 1506 1528 0.97
31 41 0.007 1.3 10.8 5.2 1 23 1534 1556 1534 1556 0.97
32 41 3.9e-06 0.00074 21.1 0.7 1 23 1562 1584 1562 1584 0.97
33 41 4.5e-05 0.0084 17.7 0.7 3 23 1592 1612 1590 1612 0.96
34 41 2.8e-06 0.00052 21.5 1.1 1 23 1618 1640 1618 1640 0.97
35 41 1.5e-06 0.00028 22.4 0.4 1 23 1646 1668 1646 1668 0.98
36 41 6.4e-06 0.0012 20.4 0.4 1 23 1674 1696 1674 1696 0.97
37 41 0.00011 0.02 16.6 3.3 1 23 1702 1724 1702 1724 0.96
38 41 6.4e-06 0.0012 20.4 0.2 1 23 1730 1752 1730 1752 0.98
39 41 0.00026 0.049 15.3 1.0 1 23 1758 1780 1758 1780 0.97
40 41 1.7e-06 0.00032 22.2 0.3 1 23 1786 1808 1786 1808 0.98
41 41 0.00012 0.022 16.4 0.7 1 23 1814 1837 1814 1837 0.97

Sequence Information

Coding Sequence
ATGCAGGAGAGTGAAGGCGATTTAGTGACAAACTTCGACAAAATGAACGCGGGGACAAAAACAACGGAATTATCAGAGCAACTAGAAACAGGCGATTCTGAGGCTCCCAAGAACAATATAATCTCGAAGAAAACCACACGACCTCACGTGAATAAAACATCATACGTTTGCAATGATTGcggaaaaaatttcacatCTGCATGGAATCTTAATATACATAGAAAATTTCACTCTGAAGAAAAACCCCATGTCTGCCAATACTGTTCTCGATCCTTTACTTTAAAGGGTGGCCTCAAAAGACATTTACGCATTCATACGCAAAAGAAACCCTTCGAGTGCACTATATGCGGAAAGAAATTTACTTTCACGCGAGACTTTGAGAGTCACAAGAGGATTCATACCGGAGAAAAACCCTATGCCTGCAACTACTGCCCTAAGACTTTCACTTGTAGTAGCGGTCTAAGGGCTCACGTCCTCATTCATATGAATGAGAAATCGTATGTTTGCGCTGACTGCGGAAAGGGTTTTAACAAAGCTTCGGATCTATGGGTGCACAGAAAATTTCACTCCGGAGAAAAACCCCATGTCTGCCAATACTGTTCTCAAGCCTTTACTTTAAAGGGTGGCCTCAAAAGACATTTACGCACACATACGAAGGAGAAACCCTTCAGGTGCACTATGTGCGGAAAGAATTTTTCGACCTCGGCAAGTCTTAAGGTTCACAAGAGGATTCATACTGGAGAAAAACCCTATGCATGCAATTATTGCCCTAAGGTTTTCACTTATAGTAAGACTCTAAGGGCTCATTTGTTCGTTCACAAGAATGAGAAATCACAAGTTTGTTCCGACTGTGGAAAGAGTTTTAATAGTGCTCCGAATCTGAAGTCTTACAGAATGACCGACAATAGAGAGAAACCCTTTGCTTGCTGCGATTGCTTTAAAACTTTCCGTAGCGATAGAGACTTCAGGAAACATAAGTGTATTCATTCGAAAGATGAACGGTTTAGATGTTCTGAATGcaaagaaacattttcttcCTCGTCACTGCTGCAAACTCAAAAGAGCGTTCACACTGAAGAAACACCTTTTACCTGCCTTTATTGCCCTAAGACCTATAAAACATGTTCCGATCGCCTGCGTCATGTTCGAAACATGCACccgaagaaaattaatgatttcgGTTGTGAGGAAAAGCACCAATCCAGCGATGAGGCTGTTGAGAAAACTGAAGCGGATCTTGTTGATCAAACTGAAATTGTTATCTCGAAAAGTGAATCAGCGTTGGAAATTAAATCTGAAAGTAACGAATATTTACAAAGAAATTGTGATGTTTTTAGTGAAACAACTGAAGCTAAGGTGATACTTAATAATTCAGAAATGAGATATATTCCGAAAAGATTGGAGACTTCGTGGGACAACGGGGCCGTTTTCAGTAAGTTAATTTTATGGCGGTTTTCAGGTCCTAATTTAGCTCTTATAGAAGAggaaacaaataatgatgGGCAAATTGAAACTATGATTCCAGAAATGCCAGTTGTGACAATTAAACAGGAGAGTGAAGGCGAATTAGTGACAAACTTCGACAAAATGATCTCGACCTTCGATGAAACGACCTCTGAATGcaaagaaacattttcttcCTCGTCACTGCTGGAAACTCAAAAGAGCATTCACACTGAAGAAACACCCTTTACCTGCCTTTACTGCCCTAAGACTTATAAAACATGTTCTGGTCGCCTGCGTCATGTTCGAAACATGCACCCGAAGGAAATTAATGATTTGGGTTGCAAGGAAAAGCGCCAATCAAACGATGAGGCTATTGAGATAAATGAAACGGATCTTCTTGATCAACCTGAAATTGTTATCTCGACGAGCGAGCCAGCGTTGGAAATTAAGTCCGAAAGTAACGGATATTCAGAAAGACATTTTGATACTTTTAGTGGAACAACTGAAGCTAAGGTGATGCTTAATAATTCAGAACTGAACATATTGGAGACTTCGTGGGACAACGGGGCCGTTTTCAGTAAGATAATTTTATGGGGGTTTTCTGATTCTAATTTAGCGCTTCTTATAGAAGAGGAAACAAATGCTGATGGACAAGTTGAAGCTATGACTACAGAAATGCCAGTCGTGTCAATTAAGCAGGAGAGTGAAGGCGAATTAGTGACAAACTTCGACAAAATGAACGCGGGGACAAAAACTACGGAATTATCAGAACAACTAGAAACAGGCGATTCTGAGGCTCCCAAGAACAATATAATTTCGAAGAAAACCACACGAGCTCACTCTAATAAAAGAACATACGTTTGCAATGATTGcggaaaaaatttcacatCTGCTGGGAATCTTAATATACATAGAAAATTTCACTCCGGAGAAAAACCCCATGTCTGCCAATACTGTTCTCAAGCCTTTACTTTAAAAGGTGGCCTCAAAAGACATTTACGCACACATACGAAGGAGAAACCCTTCGGGTGCACTATATgcgaaaagaaatttactttgATGCGAGACTTTGAGAGTCACAAGAGGATTCATACCGAAGTAAAACCCTATGCCTGCAACTACTGCCCTAAGACTTTCACTTATAGTAGCGGTCTAAGGGCTCACGTCCTCATTCATATGAATGAGAAATCGTATGTTTGCGTTGACTGCGGAAAGGGTTTTAACAAATCTTCGGATCTATGGGTGCACAGAAAATTTCACTCCGGAGAAAAACCCCATGTCTGCCAATACTGTTCTCAAGCCTTTACTTTAAAAGGTGGCCTCAAAAGACATTTACGCACTCATACGAAGGAGAAACCCTTCGGGTGCACTATGTGCGGAAAGAATTTTTCGACCTCGGGAAGTCTTAAGGTTCACAAGAGGATTCATACTGGAGAAAAACCCTATGCATGCAATTATTGCCCTAAGGCTTTCACTTGTAGTAAGAGTCTAAGGGCTCATTTGTTCGTTCACAAGAATGAGAAATCACAAGTTTGTTCCGACTGTGGAAAGAGTTTTAATAGTGCTCTGAATCTGAAGTCTTACAGAATGACCGACAATAGAGAGAAACCCTTTGCTTGCTGCGATTGCTCTAAAACTTTCCGTAGCGATAGAGACTTCAGGAAACATAAGTGTATTCATTCGAAAGATGAACGGTTTAGATGTTCTGAATGcaaagaaacattttcttcCTCGTCACTGCTGCAAACTCAAAAGAGCGTTCACCCTGAAGAAACACCTTTTACCTGCCTTTATTGCCCTAAGACCTATAAAACATGTTCCGATCGCCTGCGTCATGTTCGAAACATGCACCCGAAGGAAATTAATGATTTCGGTTGTAAGGAAAAGCACCAATCCACCGATGAGGCTATTGAGAAAAATGAAACGGATCTTGTTGATCTAGCTGAAATTGTGATCTCGAAGAGCCAGCTAGCGTTGGAAATTAAGTCTGAAAGTAAAGAATATTCAGAAAAAGATTTTGGTGTTTTTAGTGAAACAACTGAAGTTAAGGTGATGCTTAATAATTCAGAACTGAACATATTGGAGACCCCGTGGGGTAACGGGGCCGTTTTCAGTAAGATAATTTTATGGGGGTTTCCTGATCCTAATTTAGCGCTTCTTATAGAAGAGGAAACAAATGCTGATGGACAAGTTGAAGCTATGACTACAGAAATGCCAGTCGTGACAATTAAGCAGGAGAGTGAAGGCGAATTAATGACAAACTTCGACAAAATGATCTCGACCTTCGATGAAACGATCTCTGAATGcaaagaaacattttcttcCTCGTCACTGCTGGAAACTGAAAAGAGCGTTCACACTGAAGAAACACCCTTTACCTGCCTTTATTGCCCTAAGGCTTTTAAGACATGTTTTGGTCGCCTTCGTCATGTTCGAAATACGCACCCGAAGGAAATTAATGATTTGGGTTGCAAGGAAAAGCGCCAATCAAACGATGAGGCTATTGAGAAAAATGAAACGGATCTTGTTGATCAAACTGAAATTGTAATCTCGACGAGCGAGCCAGCGTTGGAAATTAAGTCCGAAAGTAACGAATATTCAGAAAGACATTTTGATACTTTTAGTGAAACAACTGAAGCTAAGGTGATGCTTAATAATTCAGAACTGAACATATTGGAGACTTCGTGGGACAACGGGGCCGTTTTCAGTAAGTTAATTTTATGGGTGTTTTCTGATTCTAATTTAGCGCTTCTTATAGAAGAGGAAACAAATGTTGATGGACAAATTGAAGCTATGACTCCAGAAATGCCAGTCATAACAATTAAGCAGGAGAGTGAAGACGAAGTAGGGACAAACTTCCACAAAATGAACGCGGGGACAAAAACTACGGAATTATCAGAACAACTAGAAACAGGCGGGTCTGCACCTCCTAGGAATAATGAAATCTCGAACAAAAATACTCGAGTTCACGCGAATAAAACATCATACGTTTGCAATGATTGcggaaaaaatttcacatCTGCAAGTAATCTTAATACACATAGAAAAATTCACTCCGGAAAAAAACCCCATGTCTGCCATTACTGCTCGCGAGCCTTTACTTTGAAGAGTGGCCTCAAACAACATTTACTTATTCATACAAAGGAGAAACCCTTTGAGTGCACTATGTGCGGAAAGAAATTTACTTCTTCGCAAAGACTTAAATGCCACAAGAGAATTCATACCGGAGAAAAACCCTATGCCTGCACCTACTGCCCTAAGACTTTCACTTTTAGTAGGAATCTAAGGGTTCACGTGCTTGTTCATAAGAATGAGAGATCGTACGGTTGTTCTGAATGTGGAAAGGGTTTTAAGAGTGCTAAGGAACTGAAGGTGCATAGAAAATTTCACTCTGGAGAAAAACCCCACGTCTGTCCATACTGCTCTCGAGCCTTCACTTTGAAGGGTGACCTCAAAAGACATTTACGCATTCATACGAAGGAGAAACCCTTCGAGTGCACTATGTGCGGTAAGAATTTTCCGACCTCGGCAAGCCTTAAGGTTCACAAGAGGATTCATACCGGAGAAAAACCCTATGCCTGCTCTGACTGTGGAAAGAGTTTTACAAATGGTCCGAATCTGAAGatgcataaaaaaattcattctagAGAAAAACCCCATATCTGTCCATACTGCTCTCGAGCCTTTACTTTGAAGAGTGGCCTTAGAAAACATTTATGCATTCATACGAAGACGAAATCCTTCGAGTGCACTATGTGCGGAAAGAATCTAACGACCTCGGTAGGCCTTAGGGTTCACATGAGGATTCATACCGGAGAAAAACCCTATGCCTGCAACTACTGCCCTAAGACTTTCACTTGTAGTAGCGGTCTAAGGGTTCACGTACTCGTTCATAAAAATGAGAGATCGTATGTTTGTTCTGACTGCGGAAAGGGTTTTAACAGTCCGATGAATCTGAAGTCTCATAGGAGCGTCCATACTGGAGAAAAAACCTTTATCTGCCTTTATTGCCCTAAGGCCTTTAAAACACGTTCCGGCCGCATACGTCACGTTCGAAGCATGCACCCGAAGGAAATTAATGATTTCGGTTGTAGGGAAAAGCACCAATCCAGCGATGAGGCTGTTGAGATAAAAGAGACGAATCTTGCTgatcaaaatgaaattgtgaCCTCGAAGAGGGATTCAAAGTTAGGAATTAAGTCCGAAAGTAACGACTATTCAGAATGgaattttgatgtttttaatgaaacaacTCAAGCGAAGAGCGAGACAAAATATTCCCAgcaagaaattgcaaaaattgcaaaggtTGCTCAATCCACGGTGAGCAAAATCATTAAGTCCTTGCAGGATGACTTGGCGGAACCAACAAGTTCAAGGAAGAACTGCGGAAGGAAATCCAAATTTTGCCCAAGAGATACGATGCAGCTCGTCCGTGCAAAGCTAGCTAACAGATGGGCTACAAGAATCGAGTTGGCAGCTCGTTTAAGCGAAGAAGGATTGGAAGTTTCGGCCAGAACTTTTAGACGAAATTTGAAGGAAGAAGGATTGAATGCCCGTCGCCGTCGAAAAAAGCCTAAATTAACGCCTAGAATGATCGCAAAACGCTTATCTTGCGCAAAAGAACTGAGACATTCGTCTGCTGAAGATTGGGAAAATGTATGTTTCTGTGatgaataa
Protein Sequence
MQESEGDLVTNFDKMNAGTKTTELSEQLETGDSEAPKNNIISKKTTRPHVNKTSYVCNDCGKNFTSAWNLNIHRKFHSEEKPHVCQYCSRSFTLKGGLKRHLRIHTQKKPFECTICGKKFTFTRDFESHKRIHTGEKPYACNYCPKTFTCSSGLRAHVLIHMNEKSYVCADCGKGFNKASDLWVHRKFHSGEKPHVCQYCSQAFTLKGGLKRHLRTHTKEKPFRCTMCGKNFSTSASLKVHKRIHTGEKPYACNYCPKVFTYSKTLRAHLFVHKNEKSQVCSDCGKSFNSAPNLKSYRMTDNREKPFACCDCFKTFRSDRDFRKHKCIHSKDERFRCSECKETFSSSSLLQTQKSVHTEETPFTCLYCPKTYKTCSDRLRHVRNMHPKKINDFGCEEKHQSSDEAVEKTEADLVDQTEIVISKSESALEIKSESNEYLQRNCDVFSETTEAKVILNNSEMRYIPKRLETSWDNGAVFSKLILWRFSGPNLALIEEETNNDGQIETMIPEMPVVTIKQESEGELVTNFDKMISTFDETTSECKETFSSSSLLETQKSIHTEETPFTCLYCPKTYKTCSGRLRHVRNMHPKEINDLGCKEKRQSNDEAIEINETDLLDQPEIVISTSEPALEIKSESNGYSERHFDTFSGTTEAKVMLNNSELNILETSWDNGAVFSKIILWGFSDSNLALLIEEETNADGQVEAMTTEMPVVSIKQESEGELVTNFDKMNAGTKTTELSEQLETGDSEAPKNNIISKKTTRAHSNKRTYVCNDCGKNFTSAGNLNIHRKFHSGEKPHVCQYCSQAFTLKGGLKRHLRTHTKEKPFGCTICEKKFTLMRDFESHKRIHTEVKPYACNYCPKTFTYSSGLRAHVLIHMNEKSYVCVDCGKGFNKSSDLWVHRKFHSGEKPHVCQYCSQAFTLKGGLKRHLRTHTKEKPFGCTMCGKNFSTSGSLKVHKRIHTGEKPYACNYCPKAFTCSKSLRAHLFVHKNEKSQVCSDCGKSFNSALNLKSYRMTDNREKPFACCDCSKTFRSDRDFRKHKCIHSKDERFRCSECKETFSSSSLLQTQKSVHPEETPFTCLYCPKTYKTCSDRLRHVRNMHPKEINDFGCKEKHQSTDEAIEKNETDLVDLAEIVISKSQLALEIKSESKEYSEKDFGVFSETTEVKVMLNNSELNILETPWGNGAVFSKIILWGFPDPNLALLIEEETNADGQVEAMTTEMPVVTIKQESEGELMTNFDKMISTFDETISECKETFSSSSLLETEKSVHTEETPFTCLYCPKAFKTCFGRLRHVRNTHPKEINDLGCKEKRQSNDEAIEKNETDLVDQTEIVISTSEPALEIKSESNEYSERHFDTFSETTEAKVMLNNSELNILETSWDNGAVFSKLILWVFSDSNLALLIEEETNVDGQIEAMTPEMPVITIKQESEDEVGTNFHKMNAGTKTTELSEQLETGGSAPPRNNEISNKNTRVHANKTSYVCNDCGKNFTSASNLNTHRKIHSGKKPHVCHYCSRAFTLKSGLKQHLLIHTKEKPFECTMCGKKFTSSQRLKCHKRIHTGEKPYACTYCPKTFTFSRNLRVHVLVHKNERSYGCSECGKGFKSAKELKVHRKFHSGEKPHVCPYCSRAFTLKGDLKRHLRIHTKEKPFECTMCGKNFPTSASLKVHKRIHTGEKPYACSDCGKSFTNGPNLKMHKKIHSREKPHICPYCSRAFTLKSGLRKHLCIHTKTKSFECTMCGKNLTTSVGLRVHMRIHTGEKPYACNYCPKTFTCSSGLRVHVLVHKNERSYVCSDCGKGFNSPMNLKSHRSVHTGEKTFICLYCPKAFKTRSGRIRHVRSMHPKEINDFGCREKHQSSDEAVEIKETNLADQNEIVTSKRDSKLGIKSESNDYSEWNFDVFNETTQAKSETKYSQQEIAKIAKVAQSTVSKIIKSLQDDLAEPTSSRKNCGRKSKFCPRDTMQLVRAKLANRWATRIELAARLSEEGLEVSARTFRRNLKEEGLNARRRRKKPKLTPRMIAKRLSCAKELRHSSAEDWENVCFCDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-