Mrus038191.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Machimus rusticus
Gene Symbol
PNPO
Assembly
GCA_951509405.1
Location
OX608054.1:19186512-19194122[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 36 4.7e-06 0.00087 20.8 2.7 1 23 79 101 79 101 0.97
2 36 8e-05 0.015 16.9 1.5 1 23 107 129 107 129 0.97
3 36 5e-06 0.00094 20.7 0.8 1 23 135 157 135 157 0.98
4 36 2.1e-07 3.9e-05 25.1 0.4 1 23 163 185 163 185 0.97
5 36 2.7e-06 0.00051 21.6 0.3 1 23 191 213 191 213 0.97
6 36 3.6e-05 0.0068 18.0 1.3 1 23 219 241 219 241 0.97
7 36 1.6e-06 0.0003 22.3 0.4 1 23 247 269 247 269 0.98
8 36 0.0012 0.22 13.2 2.5 1 23 275 297 275 297 0.96
9 36 1.5e-05 0.0028 19.2 0.1 2 21 304 323 303 324 0.93
10 36 0.032 6.1 8.7 6.1 1 21 331 351 331 352 0.93
11 36 0.0099 1.9 10.3 0.8 1 17 359 375 359 376 0.86
12 36 0.0047 0.87 11.4 2.8 1 23 387 410 387 410 0.97
13 36 1.6 3e+02 3.4 0.1 5 20 548 563 547 564 0.92
14 36 0.0091 1.7 10.5 0.4 1 23 572 595 572 595 0.95
15 36 9.1e-07 0.00017 23.0 2.4 1 23 763 785 763 785 0.98
16 36 8.1e-06 0.0015 20.1 2.1 1 23 791 813 791 813 0.97
17 36 2.1e-06 0.00039 21.9 0.7 1 23 819 841 819 841 0.98
18 36 2.2e-06 0.00042 21.8 0.9 1 23 847 869 847 869 0.96
19 36 1.9e-05 0.0035 18.9 2.4 1 23 875 897 875 897 0.97
20 36 5.6e-06 0.001 20.6 0.2 1 23 903 925 903 925 0.98
21 36 8.8e-07 0.00017 23.1 0.6 1 23 931 953 931 953 0.98
22 36 6.2e-06 0.0012 20.4 1.2 1 23 959 981 959 981 0.97
23 36 0.00031 0.058 15.1 4.3 1 23 987 1009 987 1009 0.97
24 36 0.0026 0.49 12.2 5.0 1 23 1015 1038 1015 1038 0.98
25 36 2.4e-07 4.5e-05 24.9 3.4 1 23 1206 1228 1206 1228 0.99
26 36 1e-05 0.0019 19.7 1.8 1 23 1234 1256 1234 1256 0.97
27 36 4.2e-06 0.00079 20.9 0.2 1 23 1262 1284 1262 1284 0.98
28 36 0.00016 0.029 16.0 2.9 1 23 1290 1312 1290 1312 0.95
29 36 2.2e-05 0.004 18.7 0.4 1 23 1318 1340 1318 1340 0.97
30 36 3.6e-05 0.0068 18.0 1.3 1 23 1346 1368 1346 1368 0.97
31 36 2.2e-06 0.00041 21.8 0.5 1 23 1374 1396 1374 1396 0.98
32 36 1.6e-07 3.1e-05 25.4 0.8 1 23 1402 1424 1402 1424 0.98
33 36 1.9e-07 3.5e-05 25.2 0.4 1 23 1430 1452 1430 1452 0.98
34 36 0.0011 0.21 13.3 6.0 1 23 1458 1480 1458 1480 0.97
35 36 0.00042 0.078 14.7 0.4 3 21 1488 1506 1488 1507 0.96
36 36 0.0046 0.86 11.4 4.2 1 23 1514 1537 1514 1537 0.97

Sequence Information

Coding Sequence
ATGGAACTTAGGGCTCCTAGCCCCTcacaaacaaaaatgcaaacaGCTGGGAAGAAGTTTACTTCAGCTGTGACAATTAAGCAGGAGAGTGAAGGCGAATTAGGGAAAAACTTCGACATAATGACTGCGGCGACAAAAAATACGGAATTATCAGAACAACTAGAAACAGGCGAAGCTTCCagcaacaataaaatttcgaagaaAACCACACCAGTTTACACGAATAAAACATCACACGTTTGTAATGATTGTGGGAAGAGTTTCACATTTGCATATAAACTTAAGGAGCATAGAAAAATTCACTCCGGAGAAAAATCCCATGTCTGCCAATACTGTTCTCAAGCCTTTACTTTAAAGGGTGGCCTCAAAAAACATTTACGCATTCATACGCAGGAGAAACCCTTCGAGTGCTCTATATGCGGAAAGAAATTTGCTTTCTCGCGAGACCTTACGGATCACAAGAGGATTCATACCGGAGAAAAACCCTATGCCTGCAACTACTGCCCTAAGACTTTCACTTATAGTAGCAATCTAAGGGCTCACGTCCTCATTCATATGAATGAGAAATCGTATGTTTGTTCTGACTGCGGAAAGGGCTTTAACAAACCTTCGGATCTATGGGTGCATAGAAAATTTCACTCTGGAGAAAAACCCCATGTCTGCCAATACTGCTCTCGAGCCTTTACTTTAAACGGTGGCCTCAAAAGACATTTACGCATTCATACGAAGGAGAAACCCTTCGAGTGCACTATATGCGGAAAGAAATTTGCTGCATCGGGAGACCTTAAGCGTCACAAGAGGATTCATACCGGAGAAAAACCCTATGCCTGCAACTACTGCCCCAAGACTTTCACTTGTAGTAAGAGTCTAAGGGCTCACGTGTTCGTTCACAAGAATGAGGTATCGCAAGTTTGTTCTGACTGTGGAAAGAGTTTTAATAATGCTCCGAATCTGAAGTCTCACAGAATCACCGACAATAGAGAGAAACCCTTTGCTTGTTGCGATTGCTCTAGAACTTTCCGTAGCAATAGGGACTTCAGGAAACATAAGTGTATTCAATCGAAAGATGAACTGTTTAGATGTTCTGAATgcaagaaaacattttcttcctCGTTACTGCTGCAAACTCAAAAGAGTGTTCACACTGAAGAAACACCCTTTACCTGCCTTTATTGCGCTAAGACCTTTAAAACACGTTTCGATCGCCTCCGACATGTTCGAAACATGCATCCGAAGGATATTAATGATTTCGGTTGTAAGGAAAAGCACCAATCCAGCGATGAGGCTGTTGAGAAAAATGACACGGATTTTGTTGATCAAACTGAAATTGTGATCTCGAAGAGCGAGCTAGCGTTGGAAATTAAGTCCGACGAATATTCAGAATATTCAGAAAGGAATTTTGATGTTAATGAAACAACTGAAGCTAAGGTAATGCTTAATAATTCAGAAATGAGAGATAATCCGAAAATATTGGAGACTCCGTGGGACAACGGGGCCGTTTTCaAAGAGGAAACAAATGTTGATGGGCAAATTGAAACTATAATTCTAGAAATGCCAGTTCTGACGATTAAGCAGGAGAGTGAAGGCGAATTAGGGGCAAACTTCGACAAAATGACCTCTACCTTCGATGAAATAACCTCTGAATGCAAGGAAACACTTTCTTCCTCGTCACTGCTGGAAACTCACAAGAGTGCTGACACTGAAGAAACACCCTTTACCTGCCTTTATTGCCCTAAAGCTTTTAATACAGTTTCTGGTCGCCTAAGTCACGTTCAAAGCATGCACCCGAAGGAAATTATTGATTTCGGTTATAAGGAAAAGCACCAATTCAGCGATGAGGCTTTTGAGAAAAATGAAACGGATTTTGTTGATCAAACTGAAATTGTGATCCCGAAGAACGAATCAGCGTTGGAAATTAAGTCCGAAAGCAACGAATATTCAGAAAGGAATTTTGATGTTTTCAGTGAGACGACTGAAGCTAAGGTGATGCTTAATAATTCAGAAATGAGAGATAATCCGAAAATATTGGAGACTCCGTGGGACAACGGGGCCGTTTTCAAAGAGGAAACAAATGTTGATGGGCAAATTGAAACTATAATTCCAGAAATGCTAGATGTGCCAATTAAACAGGAGAGTGAAGGCGAATTAGGGACAAACTTCGAAGAAATGACTGCGGGGGCAGAAACTACGGAATTATCAGAACAACTAGAAACAGGGGGGTCTGCAGTTCCTCTGAACAATGAAATCTCGAACAAAAACACACGAGTTCACGCGAATAAAACATCATACGTTTGCAATGATTGCGGTAAAAATTTCTCATCTGCATGTAGTCTTAATAGACATAGAAAAATTCACTCCGGAAAAAAACCCCATGTCTGCCAATATTGCTCTCGAGCCTTTACTATGAAGGGTGACCTCAAAAGACATTTACGCATTCATACGAAGGAGAAACCCTTCGAGTGCACTGTATGCGGAAAGAATTTTACGACCACGGCAAGCCTTAGGGTTCACAAGAGGATTCATACCGGAGAAAAACCCTATGCCTGTTCTGACTGTGGAAAGAGTTTTAACAATAGTCCGAATCTGAACATGCATAGAAAATTTCACTCTGGAGAAAAACCCCATGTCTGCCAATACTGTTCTCGAGCCTTCACTTTGAAGAGTGGTCTCAAAAAACATTTACGCATTCATACGAACACGAAACCCTTCGAGTGCACTATGTGCGGAAAGAATCTAACGACCTCGGTAGGCCTTAGGGTTCACATGAGGATTCATACCGGAGAAAGACCCTATACCTGCAACTACTGTCCCAAGACTTTTAATTCTAGCAGCGGTCTAAGGAGTCACGTCCTCATtcataagaataaaaaatcgtATGTTTGTTCTGAATGCGGAAAGGGCTTTAACAAACTTTCGAATCTGAAGgtgcataaaaaatttcactctGGAGAAAAACCCCATGTCTGCCAATACTGTTCTCGAGCCTTTACTTTAAACGGTTGCCTCAAAAGACATTTACGCATTCATACGAAGGAGAAACCCTTCGAGTGCTCTATATGCGAAAAGAAATGTTCTTGCCCGCGAAACCTTAAACGTCATCTTCGAAGCATACACCCGAAGGAAATTAATGATTTCGGTTGTAAGGAAAAGCACCAATCCAGCGATGAGGCTGCTGAGAAAAATGAGACGGATCTTGTTGATCAAACTCAAATTGTGATCTCAAAGAGCGAGCCAGCGCTGGAGATTAAATTCGAAAGTAATGACTGTTCAGAAAGAAATGTTGATGTTTTTAGTGAAACAACTGAAGCTAAGGTGATGCTTAATAATACAGAAATGAGAGATAATCCGAAAATATTGGAGACTCCGTGGGACAACGGGGCCGTTTTCaAAGAGGAAACAAATGTTGATGGGCAAATTGAAACTATAATTCCAGAAATGCTAGATGTGCCAATTAAACAGGAGATTGAAGGCGAATTAGGGACAAACTTCGAAGAAATGACTGCGGGGGCAGAAACTACGGAATTATCAGAACAACTAGAAACAGGGGGGTCTGCAGTTCCTCAGAACAATGAAATCTCGAACAAAAACACACGAGTTCACGCGAATAAAACATCATACGTTTGCAATGATTGcggaaaaaatttcacatCTGCATGTAATCTTAATAGACATAGAAAAACTCACTCCGGAGAAAAACCCCATGTTTGCAACTACTGTTCTCGAGCTTATATTTCGAAGAGTGGccttaaaaaacatttacgCATTCATAAGAAGGCGAAACCCTTCGAGTGCACTATGTGCGGAAAGAATCTAACGTCCTCGGAAGGTCTTAGGGTTCATATGAGGATTCATACCGGAGAAAGACCCCATGCCTGCAACTACTGCCCTAAGACTTTCACTTGTAGTAGCAATCTAAGAGCTCACGTCCTCATTCATATGAATGAGAAATCGTATGTTTGTTCTGAATGCGGAAAGGGTTTTAACAAAGCTTCGGATCTGTGgatgcataaaaaatttcactctGGAGAAAAACCCCATGTCTGCCAATACTGTTCTCGAGCCTTTACTTTAAACGGTGGCCTCAAAAGACATTTACGCATTCATACGAAGGAGAAACCCTTCGAGTGTTCTATATGCGGAAAGAAATTTACTACCTCAGAAGATCTTGACCTCCACAAGAGGATTCATGCCGGAGAAAAACCCTATACCTGCACCTACTGCCCTAAAACTTTCAATTCGAATAGCAATCTAAGAGTCCACGTGCTCGTTCATAAAAATGAGAGATCGTACGTTTGTTCTGACTGCGGAAAGGGTTTTAACAGTGCGACGAATCTTAAGTCTCACAGAAGGGTCCATACTGGAGAAAAGCCCTTTGCTTGTAGCGATTGCTCTAGAACTTTCCGTAGCAGTAAGGGTCTCAAGCACCATAAATGCATTCATTCGAAAAAGGAATTGCTCGGGTGTTCTGAATGcaaagaaacattttcttcCTCATCACTGCTGGAAACTCACAAGAGGATCCGCACTGGAGAAACACCCTTTACCTGCCTATATTGCGCTAAGTCCTTTAAAACATGTTCTGATCGGCTGCGTCATGTTCGAAACATGCACCCGAAGGATATTAATGATTTCGGTTGTACGGAAAAGCACCAATCCAGCGATGAGGCTGCTGAGAAAAATGAGACGGATCTTGTTGATCAAACTCAAATTGTGATCTCAAAGAGCGAGCTAGCGTTGGAAATTAAGTCCGAAAGTCTTCGATTTAAATACAACGAACGCAAAGATGCTTTCTTGGAAGAAAACATCAAGGTGAAGGAGCCAATTCATATTTTCCAAGATTGGTTAAATGCTGCCCTAGCCACAGAAGAAATTCTAGAACCGAACGCTGCATGCGTTTCCACCGTGAGTCCttcTGGTCAGCCTTCAAGTCGCTTCGTCCTGGTGAAGGAAGTTTCCAAAGAgggttttactttttacacCAACTATGGTAGCAGAAAAGCCCAGGAAATAGCAGGCAATCCCCGTGTCgccttaaatttttactgGACCCCCCTTCGTCGGTCTGTGAGGATTGAGGGATGTGCCGAAAAAATTTCCCGAGAGAAATCTTTGGAGTATTTCCATGAACGTCCCCGTGCAAGCCAAATTGGGGCTTTGGCTAGTGATCAGAGCACGAAGATCCCGAGCAGGAGTTTCTTGGATGAGAAGGAAAAAAGGATCAAAGAGGAGCTGGGCCCCGACAAGGATGTGCCACTGCCTAACTGGGGTGGTTTTCTGGTTCGGCCCCACTTGATCGAGTTCTGGCAAGGACAAACCGATCGACTGCACGATCGCATCTGCTTCCGAAAATCCACCGATCCTAAAGAAGTCGACGGTTCCTTGGTGCATCAGGGCGAGGACGGATGGGTGTATGAACGGCTCGCTccttga
Protein Sequence
MELRAPSPSQTKMQTAGKKFTSAVTIKQESEGELGKNFDIMTAATKNTELSEQLETGEASSNNKISKKTTPVYTNKTSHVCNDCGKSFTFAYKLKEHRKIHSGEKSHVCQYCSQAFTLKGGLKKHLRIHTQEKPFECSICGKKFAFSRDLTDHKRIHTGEKPYACNYCPKTFTYSSNLRAHVLIHMNEKSYVCSDCGKGFNKPSDLWVHRKFHSGEKPHVCQYCSRAFTLNGGLKRHLRIHTKEKPFECTICGKKFAASGDLKRHKRIHTGEKPYACNYCPKTFTCSKSLRAHVFVHKNEVSQVCSDCGKSFNNAPNLKSHRITDNREKPFACCDCSRTFRSNRDFRKHKCIQSKDELFRCSECKKTFSSSLLLQTQKSVHTEETPFTCLYCAKTFKTRFDRLRHVRNMHPKDINDFGCKEKHQSSDEAVEKNDTDFVDQTEIVISKSELALEIKSDEYSEYSERNFDVNETTEAKVMLNNSEMRDNPKILETPWDNGAVFKEETNVDGQIETIILEMPVLTIKQESEGELGANFDKMTSTFDEITSECKETLSSSSLLETHKSADTEETPFTCLYCPKAFNTVSGRLSHVQSMHPKEIIDFGYKEKHQFSDEAFEKNETDFVDQTEIVIPKNESALEIKSESNEYSERNFDVFSETTEAKVMLNNSEMRDNPKILETPWDNGAVFKEETNVDGQIETIIPEMLDVPIKQESEGELGTNFEEMTAGAETTELSEQLETGGSAVPLNNEISNKNTRVHANKTSYVCNDCGKNFSSACSLNRHRKIHSGKKPHVCQYCSRAFTMKGDLKRHLRIHTKEKPFECTVCGKNFTTTASLRVHKRIHTGEKPYACSDCGKSFNNSPNLNMHRKFHSGEKPHVCQYCSRAFTLKSGLKKHLRIHTNTKPFECTMCGKNLTTSVGLRVHMRIHTGERPYTCNYCPKTFNSSSGLRSHVLIHKNKKSYVCSECGKGFNKLSNLKVHKKFHSGEKPHVCQYCSRAFTLNGCLKRHLRIHTKEKPFECSICEKKCSCPRNLKRHLRSIHPKEINDFGCKEKHQSSDEAAEKNETDLVDQTQIVISKSEPALEIKFESNDCSERNVDVFSETTEAKVMLNNTEMRDNPKILETPWDNGAVFKEETNVDGQIETIIPEMLDVPIKQEIEGELGTNFEEMTAGAETTELSEQLETGGSAVPQNNEISNKNTRVHANKTSYVCNDCGKNFTSACNLNRHRKTHSGEKPHVCNYCSRAYISKSGLKKHLRIHKKAKPFECTMCGKNLTSSEGLRVHMRIHTGERPHACNYCPKTFTCSSNLRAHVLIHMNEKSYVCSECGKGFNKASDLWMHKKFHSGEKPHVCQYCSRAFTLNGGLKRHLRIHTKEKPFECSICGKKFTTSEDLDLHKRIHAGEKPYTCTYCPKTFNSNSNLRVHVLVHKNERSYVCSDCGKGFNSATNLKSHRRVHTGEKPFACSDCSRTFRSSKGLKHHKCIHSKKELLGCSECKETFSSSSLLETHKRIRTGETPFTCLYCAKSFKTCSDRLRHVRNMHPKDINDFGCTEKHQSSDEAAEKNETDLVDQTQIVISKSELALEIKSESLRFKYNERKDAFLEENIKVKEPIHIFQDWLNAALATEEILEPNAACVSTVSPSGQPSSRFVLVKEVSKEGFTFYTNYGSRKAQEIAGNPRVALNFYWTPLRRSVRIEGCAEKISREKSLEYFHERPRASQIGALASDQSTKIPSRSFLDEKEKRIKEELGPDKDVPLPNWGGFLVRPHLIEFWQGQTDRLHDRICFRKSTDPKEVDGSLVHQGEDGWVYERLAP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-