Matr003521.1
Basic Information
- Insect
- Machimus atricapillus
- Gene Symbol
- Zfa
- Assembly
- GCA_933228755.1
- Location
- CAKOFS010000018.1:675161-676608[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 2.6e-05 0.0048 18.3 0.7 1 23 8 30 8 30 0.98 2 11 7e-05 0.013 16.9 0.1 3 23 37 57 36 57 0.97 3 11 0.00047 0.087 14.3 1.8 1 23 63 86 63 86 0.97 4 11 1.3e-05 0.0023 19.3 0.9 1 23 112 134 112 134 0.96 5 11 2.4e-07 4.4e-05 24.7 0.1 1 23 140 163 140 163 0.97 6 11 2.2 4e+02 2.8 0.6 9 23 181 196 179 196 0.86 7 11 3.2e-05 0.0058 18.0 0.2 2 23 297 318 296 318 0.97 8 11 0.0049 0.91 11.1 0.6 2 19 325 342 324 346 0.90 9 11 0.015 2.8 9.5 4.7 1 23 359 381 359 381 0.98 10 11 1.8e-05 0.0033 18.8 0.9 1 20 387 406 387 408 0.94 11 11 5.9 1.1e+03 1.4 0.1 5 13 448 456 447 457 0.86
Sequence Information
- Coding Sequence
- ATGCACCACTTGGCTAAGCTCTACCGGTGCGAGGAGTGCTCAAAGGGGTTCAATTTTGAAAAGAATCTGTTCCTGCATATTGCTTCCCACAGTACCACCCCCGCAATATGTCCAGAGTGTGGTAGGATGTTTCAGAGACTCTCCAGTTTTGTGGGGCACCTTGAAACCCACGCAGAAAGCGACAACTTCAAATGTCAAGCCTGTGGCAAGAAGTTCGAATTTGAGAAGTATTATGAGAGGCACCTGGAAAAGGATCACAGAGGTGGAGAAATGATGGCTGCTTTGTTCGTTAAAAAGAGGAATTCGAGAAACATAAATGCCAAAGTGAAGCCGTTTGAGTGTCTTGAGTGCAATAAAAGATTTAGCCAGAAAGCATCTCTGGACCGTCACAGTATGCTCCACAGTGGCATCAAGCCCTACGACTGTCCTGAGTGCGGAATGGGTTTTTCCCAACGTACCAACTTAATAACTCACATAAAGCGAGTACACACAACTAACCAAAACGCAGGAGGACAATTTCCATGCAATAGTTACTCCTGTGTTTTTAGTAAACTTAAAAGTCTTACTCGCCATAAAACGCTGAAGCACTCAAACAAGACTGAAAATAAGAAAACGGAATTGAGCTTTACGCAGATTCTCGAGCATATCATGAGTTTGCATGACCAAAATATAAGTCCTCAAACCACTTCCTTAAGCGGCCAGGTCACTATGCCTGTGGGAGATCGGATTGCTCCTAAGCAGGTATCAGAGGATCAACAATCTGTTCCAGTATGTCCGCCTACTCCTGTGAAAGCGCAGTTCGTTAACGTTGTGGACCACTTATACCCGACTAAAGAAAGGGTTAATCGCACAGTAAAGGAGATTAACATTGATGGAATTAAGTGGCTCGAGTGCCCCTATTGTCCAAAGAGGTTTCAGATGCCCTTTGACATCGTTAGGCATTTGCGCACACACACTAAAGAAAAACCTTGGAAATGCGAATATTGTGGACGGAAGTTCGCGTTAAAGGATACCATGGAATTGCATCCACACATGCATGTAGACAGAAAGAAACCGAATGAAATTACTAAACTTTACCACTGCACTTATTGCCAAATGTCGTTTGATTCGATCAGAAGGTTGCACATGCACGTACGGATTCACAGCAATTACAAACCTTACGCTTGCTCAATATGCTTCAAAACTTTCAAGAGTAATTATAATTTGCGACTGCACAAAACCATTAATGAACCAAAAGACCCAGACGGTGAAAACATAAAGCGCCAGCTTTTTACTCCCATAATTCAAAATCCAGAAGAAAAACCAGAAGAGGATCAGAGCGTCCGAATTTACCAACGTGAAAAATGTGGCCAAAGATTCAAAAGTCCTCGCATCTAG
- Protein Sequence
- MHHLAKLYRCEECSKGFNFEKNLFLHIASHSTTPAICPECGRMFQRLSSFVGHLETHAESDNFKCQACGKKFEFEKYYERHLEKDHRGGEMMAALFVKKRNSRNINAKVKPFECLECNKRFSQKASLDRHSMLHSGIKPYDCPECGMGFSQRTNLITHIKRVHTTNQNAGGQFPCNSYSCVFSKLKSLTRHKTLKHSNKTENKKTELSFTQILEHIMSLHDQNISPQTTSLSGQVTMPVGDRIAPKQVSEDQQSVPVCPPTPVKAQFVNVVDHLYPTKERVNRTVKEINIDGIKWLECPYCPKRFQMPFDIVRHLRTHTKEKPWKCEYCGRKFALKDTMELHPHMHVDRKKPNEITKLYHCTYCQMSFDSIRRLHMHVRIHSNYKPYACSICFKTFKSNYNLRLHKTINEPKDPDGENIKRQLFTPIIQNPEEKPEEDQSVRIYQREKCGQRFKSPRI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -