Basic Information

Gene Symbol
-
Assembly
GCA_933228755.1
Location
CAKOFS010000049.1:2204891-2207142[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.26 49 5.6 7.2 1 21 188 208 188 210 0.95
2 11 8.2e-06 0.0015 19.8 1.3 1 23 216 238 216 238 0.98
3 11 0.0032 0.59 11.7 4.2 1 23 244 267 244 267 0.95
4 11 0.0062 1.1 10.8 3.5 1 21 273 293 273 295 0.95
5 11 0.0001 0.018 16.4 1.9 1 23 301 323 301 323 0.99
6 11 1.1e-05 0.0021 19.4 1.2 1 23 329 351 329 351 0.98
7 11 0.00025 0.047 15.1 1.4 1 23 359 382 359 382 0.97
8 11 0.00065 0.12 13.9 3.6 2 23 389 410 388 410 0.97
9 11 0.00023 0.042 15.3 0.2 1 23 416 438 416 438 0.98
10 11 6.2e-06 0.0011 20.2 2.6 1 23 444 467 444 467 0.96
11 11 2.1e-07 3.8e-05 24.9 1.4 1 23 481 503 481 503 0.96

Sequence Information

Coding Sequence
ATGGCTGGTAAAGTGGCAGAGGTCACAGAAGTGAAAGTCGAGAATACTAACGATTTGCAGTCCTATTTGGAGTCCTTTAATCAAGAGATCGACGATGGAAATGGAACCATCCAAATACTCAAGGAGGACAGCAATGACAATGAAGAAGATGAGGGTGGGACATATTTCGTAGACCAGGCAGGTAACTATTACTATCAGGCGACCAAAGATTCAGAACCTGTGTTGACGACACCTCCTGAGGATTATGAAGAAGGCAGTGATGCTGAGGACGAGCGGCTGAATGATACTGAAGAATTCTTAGAAGACACTGATAATGAAAGTGGTAAGGATAAAAAGCCCAAAGTTTCGGCAGTAAATGCAAAGCAGACGAAAGATCAAATAAGTTTTGTTCTCATAATGGACGATGAGAACAAAGGTGATGGACAGAAGGAAGAAGTGTATGAATTCGATGAGAAAGAAGAGGATGAAGAAAAAGGTCAATCCAGCCAGGAGGACGAGAAGCCATCTAAGAAAGTTGTGAAGTTGGTACCAAAGAAAGCCACCACGGCGAATGGTCAGATCTTTTACTGTTGCTACTGCAGCTATGCAAGCACGAAGAGATACTTGCTGGCCAGACATATGAAATGCCACTCAGAAgatagaccccacaaatgctcggtatgtgagagaggatttaagacaatagcatcattacaaaatcatattaatacgcacactggcaataaacctcatcattgcaaatcctgtgaaagctcatttacgacttcgggtgagctcgttaggcacgtaaggtaccggcacacgcacgaaaaaccgcataaatgcactgagtgcgactatgccagcgtggaactgagcaaattgaaaagacatatccgttgccacacaggggaaaggccttaccaatgtccccactgcacatacgcttcgcctgatacctttaagcttaaaaggcacttgagaatacacactggggagaaaccttacgagtgcgatatttgccacgcacgattcactcaatccaattcattaaaagcccataaactgatccacagtgttggagaaaaaccagtgttccaatgtgagctatgtcccacaacttgtggccgcaaaacggatttaaggatacacgtccagaaattgcatacctcagataagcctttaagatgtaaacggtgcgggcagcatttccCAGATAGATATAGTTATAAGGTCCACTCAAAAAcgcacgaaggtgagaaatgttacaaatgcgaattatgcccatatgcctctatttcggctcgccatttggaatcccacattctcatccacactgaccaaaagccctacgaatgccagcactgcgatcaggctttTAGACAAAAACAGCTCCTTCGAAGGCATGTTAATTTGTATCACAATAAAAATTACGTTCCCCCAGTACCAAAAGACAAAACCCATGTTTGTCCGGACTGCTACAAAGCGTTTAGTCACAAAGGTAATTTAATTCGGCACATGGCTCTGCACGATCCGGAGTCTGGGGCAAAAGAGCAACAAGTGGCCTTAAAAATAGGTCGTAAGAAGCGCATTCAAGTAATTGATGGGCAGGCTGTGGAAATCTGCCCGAGCCTCGATGGAGACATGGACGATGATATGAATGAAGATGGTACTTATGACGACTCGTGTAATGCGGACAGTGTTCCTGTTACGAAGGAGAAGGAAATTGTTGCAGTGGAAGGGTCTGATGGCCAGCAGTATGTGGTTCTTGAAGTTATCCAAATGGATTCAGAAGCAGGTGGATCAACGGAAAACGCAAACGAGAACATGGAAATGAATGAAGAAGGATATATCATGGATTTGCCATCTGAAGTCATAGGCACCTTTAAGGGCAACAAAAAGCTACAAGCAAAAACAGAAGGGAGTATTATAGGAGAAGAACAGGAAATGGATAACTGCTTTGGTTTTGAGGATGATGAAAATAGTCAAGAAGCTGATGAAGATGATAAAACACAAATTAAATATGAAATGGAGGAGGAATAG
Protein Sequence
MAGKVAEVTEVKVENTNDLQSYLESFNQEIDDGNGTIQILKEDSNDNEEDEGGTYFVDQAGNYYYQATKDSEPVLTTPPEDYEEGSDAEDERLNDTEEFLEDTDNESGKDKKPKVSAVNAKQTKDQISFVLIMDDENKGDGQKEEVYEFDEKEEDEEKGQSSQEDEKPSKKVVKLVPKKATTANGQIFYCCYCSYASTKRYLLARHMKCHSEDRPHKCSVCERGFKTIASLQNHINTHTGNKPHHCKSCESSFTTSGELVRHVRYRHTHEKPHKCTECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDICHARFTQSNSLKAHKLIHSVGEKPVFQCELCPTTCGRKTDLRIHVQKLHTSDKPLRCKRCGQHFPDRYSYKVHSKTHEGEKCYKCELCPYASISARHLESHILIHTDQKPYECQHCDQAFRQKQLLRRHVNLYHNKNYVPPVPKDKTHVCPDCYKAFSHKGNLIRHMALHDPESGAKEQQVALKIGRKKRIQVIDGQAVEICPSLDGDMDDDMNEDGTYDDSCNADSVPVTKEKEIVAVEGSDGQQYVVLEVIQMDSEAGGSTENANENMEMNEEGYIMDLPSEVIGTFKGNKKLQAKTEGSIIGEEQEMDNCFGFEDDENSQEADEDDKTQIKYEMEEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00628593;
90% Identity
iTF_01184020;
80% Identity
-