Basic Information

Insect: Macaria liturata
Gene Symbol: ZFHX3_2
Assembly: GCA_964023185.1
Location: CAXIEF010000117.1:671-11812[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00029 0.022 15.7 1.8 2 23 117 139 116 139 0.95

2 16 7.2e-05 0.0056 17.6 0.7 1 23 171 195 171 195 0.92

3 16 0.011 0.82 10.8 0.4 1 22 243 264 243 267 0.91

4 16 0.076 5.8 8.1 3.3 1 23 605 628 605 628 0.95

5 16 0.0079 0.61 11.2 0.1 1 23 635 658 635 658 0.95

6 16 0.0032 0.25 12.5 2.5 2 22 713 733 713 736 0.91

7 16 0.84 65 4.8 1.1 1 23 748 773 748 773 0.91

8 16 0.013 1 10.5 1.3 1 23 791 813 791 813 0.97

9 16 0.0016 0.12 13.4 0.3 2 23 820 842 819 842 0.96

10 16 0.00028 0.022 15.8 3.1 1 23 947 971 947 971 0.92

11 16 0.012 0.9 10.7 0.7 1 22 991 1012 991 1015 0.89

12 16 0.0012 0.09 13.8 0.2 1 23 1062 1086 1062 1086 0.93

13 16 1.6 1.2e+02 4.0 0.2 3 21 1161 1179 1160 1180 0.91

14 16 0.85 66 4.8 3.5 2 19 1270 1287 1269 1292 0.91

15 16 3e-05 0.0023 18.8 2.9 1 23 1795 1817 1795 1817 0.99

16 16 0.00079 0.061 14.4 0.3 1 23 1906 1928 1906 1928 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00029	0.022	15.7	1.8	2	23	117	139	116	139	0.95
2	16	7.2e-05	0.0056	17.6	0.7	1	23	171	195	171	195	0.92
3	16	0.011	0.82	10.8	0.4	1	22	243	264	243	267	0.91
4	16	0.076	5.8	8.1	3.3	1	23	605	628	605	628	0.95
5	16	0.0079	0.61	11.2	0.1	1	23	635	658	635	658	0.95
6	16	0.0032	0.25	12.5	2.5	2	22	713	733	713	736	0.91
7	16	0.84	65	4.8	1.1	1	23	748	773	748	773	0.91
8	16	0.013	1	10.5	1.3	1	23	791	813	791	813	0.97
9	16	0.0016	0.12	13.4	0.3	2	23	820	842	819	842	0.96
10	16	0.00028	0.022	15.8	3.1	1	23	947	971	947	971	0.92
11	16	0.012	0.9	10.7	0.7	1	22	991	1012	991	1015	0.89
12	16	0.0012	0.09	13.8	0.2	1	23	1062	1086	1062	1086	0.93
13	16	1.6	1.2e+02	4.0	0.2	3	21	1161	1179	1160	1180	0.91
14	16	0.85	66	4.8	3.5	2	19	1270	1287	1269	1292	0.91
15	16	3e-05	0.0023	18.8	2.9	1	23	1795	1817	1795	1817	0.99
16	16	0.00079	0.061	14.4	0.3	1	23	1906	1928	1906	1928	0.98

Sequence Information

Coding Sequence: ATGATGTTACCTAATGGAACATGTGATGACAGAAGACCGAGCCCCAACCAGTGGAGACCTCCTCGGTCGATAGCTGAGTCTCTGATGCCTCAACATTCCTTGATCTCTGTGGCGCATCCACATACTATCAATGCGTCGGTACAACCTCGGGCTAGTCCGAATTCTTCACCGCCGTTCCAAGCAACCCCACCAGCTTTCCTCTCAGGAACGACGATAGGTGTTTGTCCTGATCACCTCGGTGGACGACCATCTGGTGCCGACTGTCCGAAGTGTGAGCTAATTTTGAATTCAGGGAGACTGGGTGGCCCTCTTGCTGGCATGCATAGTCGGAATTCCTGCAAAACTCTGAAATGTCCAAAATGCAATTGGCATTACAAATATCAAGAAACTTTAGAAATCCATATGAAGGAAAAACATCCCGAAGCTGAAACAAGTTGCATTTATTGTATAGCTGGTCAACCGCACCCGCGGCTGGCTCGCGGTGAAACCTATACCTGTGGGTACAAACCTTACAGATGCGAAGTATGCAATTACTCTACTACGACCAAAGGAAATCTAAGTATCCACATGCAATCAGACAAGCATTTAAATAACATGCAGGAGCTACAGAACGGAGGAAATCCAGGAGAAGGAAGTATACCACCTGCACCGCAACATACACCTCCTGGCCCTCACAAGCCTCCACTGCCGCATCATTCTCCCTTAGGCCAAAAGCCTAAGCCTACTTTCCGATGTGATGTTTGTAATTACGAAACAAACGTGGCCAGGAACTTAAGAATACACATGACATCAGAAAAGCATACTCACAACATGCTGGTTCTTCAGCAGAATGTCAAACATATGCAGACCTTGTCAGTTTTACATCACAGGCAGCAGAGTCAGCAACAGCTGGAAAGCCTTCTTCATTTCCATGGAGGAGACGCTCCGCCGCCCAACACGGAAGCTGCTCTCGCAGACATGGCATACAACCAGGCTGTGATGATCCAACTAATGACTGGAGGACCAGGGCCTTCACCTCCTGAACTTGGTGCTCACCTCGATGTTGGTCTCAACCCTGAAGCTATGGAGCCGCCCCCGGAGCCGGCGGACCCTGAGCCCGAGAGAACCTTCCACTGCTGCATTTGCAATTGCTTCTCTACTGACTCTTTAGAAGCATTAGGACATCATTTAGCGCAAGACCGTACAAAGATCAGAGAGCAAGAAATACTGGCTCTTGTGGCTGGACATTACGTCTGTAAACTCTGCACTTATAAGACGAATTTGAAAGCAAACTTCCAGCTTCATTGCAAGACTGATAAGCATTTACAGCGACTGCAGCATGTCAACCACGTCAAGGAAGGTGGCCCGAGAAACGAGTGGAAATTGAAATTCTGTGGTGGAGTTGGAACAGGAGGCGCTGGCGTTGGCGGTGTTCAAGTCCGATGCTGCGCCTGCGACTATTACACGAATTCAGCTCACAAGCTGCAACTTCATGCAGCTGGCGCGAGACACGAAGCAGCCACGCTTCTACTGAGACACCTACGAGATTGTGCATCAAGGATTCCTCGGGAACGCAAAGACCCGACACCAGATGTCGCCGAGCTCTTCCAAGTTATCCCTCAGCCTCCTGAGTTGACGAGTCCTTTCGACCAGCAAGATAATGATTCTAAAGAACCGATCGATCAGAAGCCGGAGTTGACTCAAGAGCAGAAGATGTTGCGATTCTTGGAGCAGCACCAGCAGCAGCAACAACAACAGCAGCAGTCGCTAGGGCAGACCGATCAAGTTAATCAACAAACTCGAAATGAAGAAGACCGCGAAACACCCGGGCCTCACGCTTGCCCCTACTGCAACTTCAGCTGCACCAGCGAGGGCCGCCTGCACGCCCACGTGAACTCCATACACGGTGACAGCGCTCGTCATTTCATCTGTCCCCTTTGCCAAGACGCGTTCAAAGATCGTCCTTCACTTGAGAGACACGTAATGCAAATCCATTCTGTCAACTCTGAAGGACTGCAACGACTACTACTGCTTGTCGATCAAAGCCACTGGCTGAATGGAGCGAACCAAGCGCAAAGAGATGAGAACCGACAAGGTGATGAAGAACGAGAGATTTCCTCGCCTAGGTCAGAGGGAAGCACTGACGGCGAGATCGAAAGGTGCTCTACATGCAATCGTACTTTCCGAAATGTAGATGAATTGTGTCAACATCAAAATGAGTCTGGCCATCTTGAGCTGAAGCAGACGCCCCAAGGCCCTGGATATTTCTGCTGGAAGAAAGGATGCAACAGGTACTTCGACGCGGCGCACGCCCTACAGAATCACTTCAGGGAAGCTCACGCCCGCAACTCTACCACCAACATGTCTGTATCAGAGAAACATGTCTACAAGTACCGTTGCAATCAGTGTAGTTTGGCTTTCAAAACAATAGAGAAATTACAACTGCACTCGCAATATCACGTCATCCGAGACGCAACCAAATGTGTATTGTGCGGTCGGAGTTTCCGATCTGTACTAGCTTTACAAAAACACGTTGAAACGTCCCACTCTGAGCTATCCGAAGAAGAGTTAGCCGCATTCAAGCGCAGTCTGGCATCAAATCCTTTATTGCAAGCTAATCAAGCTACGGCCCTTGATGCTACTACAGCGGAGCTTCTACGTAAAGAGCTGAGAACTCCCGATGATGAGATGGCAGACCTAGAAGACAGAGATTCGAGTGCTACTGTAGCAGATGAATCCGGCCACAATGACGCTGAAAATTCTGATGATTCCATAATTTACAAAGATCAACAGTTTTTGGAAGATTTCCTGAATTCCCAAGCTATGGCCGAAGATTCCTACAATGACCCTGCAAGGAAATACAAATGCCACCGATGCAAAGTGGCATTCACGCGCCAATCATATTTGACCGCTCACAATAAAACACTCCTACACAGGAAAGGTGAGAAGCTTACATATCCGATGGAGAAATATCTCGACCCCAATAGGCCATTCAAATGCGACGTTTGTAAAGAATCATTcacgcaaaaaaatatcttgctCGTTCACTACAACAGCGTGAGCCATTTGCATAAATTGAAACGCGCTATGCAAGAACAACAGAACAATAACAACCCTCCCGTCTCGCCCGGGGCGGGTTCCGCGCCGTCCAATTTGACTCTTACGCCAAAAAGTACTTCTAGCGAAGAGGACGACCGAAAACGTTATAAATGCAATATTTGTAAAGTGGCATACACTCAAGGCAGCACGCTAGATATTCACATGAGGTCCGTCCTGCACCAAACCCGCGCGGGCAAGTTACAGGAACTCGCCGCGGCCGGACACGTGGACTTATCTCGGCCTTTAGTCGAGCAGCCGGACAGAAACGACCCCGCCAAAATATTACAAGACGTGTTGTCGCCGAAAAATACATCCCCTTCGTCGACATCGAGCGGGGGTCCGCGCTCGTCTCCCCCCGCGCGCGCAGGTAGCCCGCGCTCCCCGCGCCCAGGTAACGCCTCGTGCGATCGCTGCCACGCGTCATTTCCTACCGGGGAGCTACTCGACGCACATCGCTCGACCTCATGCCCGTTCGGCGATGCGCGCGCGCAGTCGCCGCTAGGTGAAGCCGAGGCAGCGGCGCTAGACGAGATGGTGGCCAAGGGCAACCCGCCCAAACGCAACTCACAAATGTATAAACAACTTTTAGAGACCTTCGGCTTCGACCTCGTCATGCAGTACAATGAGAACCAGCGGCGCAAGATGCAAGAGGAGCGTGAGATGGCGCGAGTGCCGAGCCCGCCGCCCCCGCCGCCCGAGGAGAAGCCGCCGGATGGTGAAACCAAGTCGACGTGCCAACATTGCAATAAGGAGTTCTCGAGTGTGTTCGTGCTAAAGACCCATTGTGAAGAAGTGCATAAAGACAAAGTGCCGTTGGAGTTTTTGGAGCAATTCGCGGAGCAGTTTAAATCTGAGTATGAGAGGAAGTCTGGTGCTCCGAACTCGCCGCGCGCGTCTCCGGCTCCTCAGGGAGACCGGTCGCCCTCTCCGCGCGGGGAAGGCAACTTCAATGACAATAACAACGCCCAAGGTGAAGCTCAGGCCGGGGCTCTGTTGGCCGCCCAGGTGCAGGAGATGCAGGCGGCCCTGAACATGATTCAGCTGCAACAGCTGGGACAGCTGCACCCGATGGTGGCTCAGATGCTCTCGCTGGGTCTTCCTCTGGGCCTGAACGTGGGTGCGCTGGCTGCCATGAACCTGCAGCCGCCCCTGGTGCCTCTGATGCTGCCGCCGCCGCCCTTCGACGCCATGCCCTTCGGACACGACGCACAGCTCAAACAACAACAGCTGATACAGCAACAACAGCAGGCTAATGCTGCTGGACAAAAGCGAGCTCGTACTCGTATCACTGATGAGCAGCTGAAAATACTTCGAGCTCACTTCGACATCAACAACTCCCCAAGTGACGAAGCTATTGCGAAGATGGCCAAACAATCCGGCCTGCCAACCAAGGTAATCAAACATTGGTTCCGTAACACCCTTTTCAAAGAAAGGCAGCGCAATAAGGACTCTCCTTACAACTTCAACAACCCTCCATCGACGACACTCAACCTTGAAGAGTATGAGAAGACCGGTGAAGCCAAAGTTACACCTTTAGACTCATCCGCTAGTTCTGATGAAGGCAAACCGCCACCAGAAAAGAAACCCAAGATTGAAGATATCAATATGCAACACCAACAGGAGGTGAAATCGGAGCCTATTGATGAACCATCCATGGAAGAGAAGTACGTGTCATACGATGATAGACATCAGGAGGATAAAAGCTTCATATTTCCTCAAGCGCCATCACAAAGCCCGGCGCCATTGTTGAACAGCTCAGATCATCTTCATCATAATATGTCAAGGCCGCAGACTCCGACGCATATATCGCTGAACTCTTTGATTCAGTCGCAACTGGATTCGATACCGGCGACCAGTATACCGCAGCCTCCACATCCGTCGATGTTACCACCAAAGATGAATCCTAACTTCACGTCCCCAAACTCCGCGCCCCCGAACGTCCTACCTTTGACCCCAAATCGCAGCCTCAGTCCCGGCAGGGGACCGGCCGATTTCGGACTTTCCGGGGGCAACTCGAACGGATCCAACAGCTCGGGGTCTTCTGGCAAACGCGCCAACAGAACTAGATTTACCGATTATCAGATAAAAGTTCTGCAAGAGTTTTTTGAGAACAACGCATATCCTAAAGATGATGATCTTGAATATCTGTCCAAGTTACTGGGACTAAGTCCTAGAGTGATCGTGGTTTGGTTTCAAAACGCACGACAGAAAGCAAGAAAAGTCTACGAGAACCAACCAGCTGCCGATCCGCCCGCGGGAGCCACAGATGATGCCAACAGATTTCAACGCACTCCTGGCCTCAATTATCAATGCAAAAAGTGCCAACTAGTATTCCAGAGATATTATGAGTTAATAAGACATCAGAAGACTCATTGTTTCAAAGAAGAAGATGCGAAGAGGTCGGCTCAAGCTCAGGCTGCAGCAGCACAGGTGGCTGCCACCCTGAGCAGCGAGGACTCCAACTCAAGCACGGTGGAGCACCACGCCCCGCACGTGCCGGTGTCCCCCGCGCCCCCGCGCACGCCCACCCCCGCCGCGCCCAACTACCCAGTGTCTCCGGCACCTCCAGCGCCGCTCACTCCAGTGACTCCTCTCTCTCATCAGCAACAACAACGCAATGATGATAAAGATGGCAGTTTTCAATGTGATAAGTGCAACCTAGTCTTCCCAAGATTTGATTTATGGCGAGAACATCAGCTGGTTCACATCATGAACCCAAATTTATTCCCCACTTATCCACCAGATTCCCCTTTTGGGATTTTGCAGCAACATGCACAGCTACAACAGCTCAACGCTCTTGGAAGTGAAGAAGCTCGCCATCCTCTCGTTGCTGCATTAAATCAACAAGTAGCTAAAAGAAAATTTGATGAATTCGAGGAAGCAGATACTGGAGAACAACCTAAGGACAAACGTCTTAGAACTACGATCCTACCTGAGCAATTGGATTATCTCTACCAAAAGTACCAAATCGAGTCTAATCCATCTCGCAAGATGCTTGAAATATTGCACGTGAGCACAACAGAACGCGGCGGGAACAACGAAACGTCTGAGAGACGCCCCGAACATGGAAAATCAGAGATACCCTTAGATCTTAGCAAACCCGTAGACCTGTCACGACCCGGATCTGACGCCGACGAGCGATCGGACACCGCTTCAGAAACCATGGAGTTTTACGAAGAAGATGATCCAACATCGCCTTTGCCAGGCCAGCAGCTAACGCCGAGACAGCCCGGCAAACGCTACCGTCACAAATGTCATCCGTACAAGTCAAAATCATGA
Protein Sequence: MMLPNGTCDDRRPSPNQWRPPRSIAESLMPQHSLISVAHPHTINASVQPRASPNSSPPFQATPPAFLSGTTIGVCPDHLGGRPSGADCPKCELILNSGRLGGPLAGMHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGNPGEGSIPPAPQHTPPGPHKPPLPHHSPLGQKPKPTFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSVLHHRQQSQQQLESLLHFHGGDAPPPNTEAALADMAYNQAVMIQLMTGGPGPSPPELGAHLDVGLNPEAMEPPPEPADPEPERTFHCCICNCFSTDSLEALGHHLAQDRTKIREQEILALVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKFCGGVGTGGAGVGGVQVRCCACDYYTNSAHKLQLHAAGARHEAATLLLRHLRDCASRIPRERKDPTPDVAELFQVIPQPPELTSPFDQQDNDSKEPIDQKPELTQEQKMLRFLEQHQQQQQQQQQSLGQTDQVNQQTRNEEDRETPGPHACPYCNFSCTSEGRLHAHVNSIHGDSARHFICPLCQDAFKDRPSLERHVMQIHSVNSEGLQRLLLLVDQSHWLNGANQAQRDENRQGDEEREISSPRSEGSTDGEIERCSTCNRTFRNVDELCQHQNESGHLELKQTPQGPGYFCWKKGCNRYFDAAHALQNHFREAHARNSTTNMSVSEKHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRDATKCVLCGRSFRSVLALQKHVETSHSELSEEELAAFKRSLASNPLLQANQATALDATTAELLRKELRTPDDEMADLEDRDSSATVADESGHNDAENSDDSIIYKDQQFLEDFLNSQAMAEDSYNDPARKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNPPVSPGAGSAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSTLDIHMRSVLHQTRAGKLQELAAAGHVDLSRPLVEQPDRNDPAKILQDVLSPKNTSPSSTSSGGPRSSPPARAGSPRSPRPGNASCDRCHASFPTGELLDAHRSTSCPFGDARAQSPLGEAEAAALDEMVAKGNPPKRNSQMYKQLLETFGFDLVMQYNENQRRKMQEEREMARVPSPPPPPPEEKPPDGETKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYERKSGAPNSPRASPAPQGDRSPSPRGEGNFNDNNNAQGEAQAGALLAAQVQEMQAALNMIQLQQLGQLHPMVAQMLSLGLPLGLNVGALAAMNLQPPLVPLMLPPPPFDAMPFGHDAQLKQQQLIQQQQQANAAGQKRARTRITDEQLKILRAHFDINNSPSDEAIAKMAKQSGLPTKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLDSSASSDEGKPPPEKKPKIEDINMQHQQEVKSEPIDEPSMEEKYVSYDDRHQEDKSFIFPQAPSQSPAPLLNSSDHLHHNMSRPQTPTHISLNSLIQSQLDSIPATSIPQPPHPSMLPPKMNPNFTSPNSAPPNVLPLTPNRSLSPGRGPADFGLSGGNSNGSNSSGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAADPPAGATDDANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSTVEHHAPHVPVSPAPPRTPTPAAPNYPVSPAPPAPLTPVTPLSHQQQQRNDDKDGSFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNALGSEEARHPLVAALNQQVAKRKFDEFEEADTGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLEILHVSTTERGGNNETSERRPEHGKSEIPLDLSKPVDLSRPGSDADERSDTASETMEFYEEDDPTSPLPGQQLTPRQPGKRYRHKCHPYKSKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00935502;
90% Identity: iTF_00935502;
80% Identity: iTF_00935502;