Mlit011521.2
Basic Information
- Insect
- Macaria liturata
- Gene Symbol
- PLAGL1_1
- Assembly
- GCA_964023185.1
- Location
- OZ026814.1:10318162-10320572[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.12 9 7.5 0.5 5 23 370 388 369 388 0.95 2 12 0.0059 0.46 11.6 0.4 3 23 396 416 394 416 0.94 3 12 0.012 0.92 10.7 0.8 2 23 424 445 423 445 0.95 4 12 3.4e-07 2.6e-05 25.0 0.7 2 23 451 472 451 472 0.97 5 12 0.0078 0.6 11.2 3.9 1 23 478 500 478 500 0.98 6 12 0.0089 0.68 11.1 0.2 2 19 505 522 504 524 0.93 7 12 0.0002 0.016 16.2 0.2 1 23 555 578 555 578 0.94 8 12 0.0017 0.13 13.3 0.0 3 23 587 607 586 607 0.98 9 12 0.00011 0.0084 17.1 0.7 1 23 616 638 616 638 0.98 10 12 4.2e-05 0.0032 18.4 4.6 1 23 644 666 644 666 0.98 11 12 0.0016 0.13 13.4 0.3 3 23 674 694 672 694 0.98 12 12 7.6e-06 0.00059 20.7 0.7 1 23 700 723 700 723 0.96
Sequence Information
- Coding Sequence
- ATGGAGACTTGGACAGACCTTTGCCGTTGTTGCTTGTCCGCCAATACTGAAGTGTCACTTTTGGATAAAGAGCAAAATATTTCACAAAGATTTCTTGAAGTGACTACGGTTGAGGTTAAATTGGATGACGGTTTGCCTCAAAAACTGTGTGGCGAGTGCTACTCCAGCATGAACATGGCGTACCAGTTCCGGAAGCAATGCATCAAGATGGATACAGAGTTAAAAACTCAACTAAACACCCTCCTCAGTCAATGTGATCAAAGTAACATTGATAACTTTGAAAATGCAGCAGAAATGGGTGAAGAGGATTCAGATGTCGCTTTTGCCAATGATCCGATGAAACAACTTGAAGCGGTCATAAAAAAAGAACCAATGGACAGTGATGATGACTTCTACTATGTGCTAGTTATAGACAACCCAAAAGATAAGGAAAATGCTGACGAACAGCATTCAGCTACTGCAAAAAAAGCTACAGGGTTAAataatgcaaaaataaaatctgaaataCTAGATTCAAATGATGATAAAAGTGAtttaacaaattacaatatacaAATCAGTCCTGGATTTTCACAAAATAAGGAAATATTGGGTGTTACTTTAAACCAAGAAAATACTATACAAACAAGTCGTAACTTTGAGAAGACAATGGACTCATTTCTGATGACAAACCAAATTCCCGCCAAAGTTCCTGCCACAATACTGGAGAATGAAGAAGAGGAACAACTTCAAGAGGCTGAGGAACCTATGCAGATTGAGGAAACACAGGATAGCACATCTCAAGACACACAAAATTATCAAGCAGATGAAaatacagaagatgagcaaccAATAACTGAtcaaaatttgattaaaatccTCACAACTGCCAGTGAAGATGGCACAATACTATTAAACAGTGATACCATGGTACAGTATATTACCAACGATGGTCAGCTATTGATGAATAATGAAGAAGGCGACCAATCACAGGAGGTCATCTTATGTGAGGGAGACGAATCACAATTCCAGATTGTCAAGTATGATGGATCAGAATTGGTGATAGAATATGCAGATGACAGCACCATAGCAACTGTACTACAGCAAGATGATGACTCTTATATCTGTGAATGTGGAGAACAGTTTCAGGATGTGGAAGAGCTGGAGAAACATCAGCACCAACACAACCCTGCGGGGGAACATCTATGCAATATGTGTGGAAAAGGATTTGAGTCCTCTGAGATCTTAACTGGTCACATGTTACTACATAATGTACCAGGCTTGCTTCTACAGTGTCCATTCTGTGACCAAGTCGTGAAACGTAGCACTCTGACACAGCACATCAAATATTTCCACAACAACATCAAGCCACAGTGTGAGATTTGCACAAAAACATTTGCAAATCCAAACAACTTGAAGCGTCACATGACAATACACACAGGCGTGAAAGATTTCTCTTGCGATATCTGTCTAAAACGGTTCCATCAAAAAATTACCATGCAGACTCATAGACTGACTCATATGAACCCTTTGAATTGTCCTCAATGTGAACTCTCATTCAAGGACAAGGAAACATTTGAGGAGCACAAGGTTGATGGTGTTTGTCCAAAGAACAGAGCAAAGGAAGAACTAATAAAGACTGTCAAACAAGAGATCACAACCAGCTTGGGCAAGCTTTTAGGTTATGCATGCTCTTTGTGCAAGAAAATGTTCTCAATAGAGTCCGCTTTAGAGAAGCACATTGAGTTGTCACACATGGTCGATCCTACCGAGCTATTGTGCTCAGAATGTGGAGAAGTTGTGTCTTCAAAAGCGGAGATTGAAGCCCACATGATAAGTCACAACAAACGCAAGTCCGTGAAGCGGTTTGAATGCCAAACCTGTGGTAAAGGATGTTCAAGCCAAGCGATGCTGTTGATGCATGAACGAGTCCACACAAACGAAAGACCATTCTCATGTCAACTGTGTCCACTCAAATTCAAAACCAAGACCCATCTGCGAACTCACCAACTAACCCATACGAGAGAGAAGAAGTTTGGTTGCTCAATTTGTATGAAGTTCTTTGCCCTGAAAGGTAATTTAGTAGTACATCTACGTACACATACGGGAGAGCGCCCATATGTCTGTAATGTGTGCGGAGAAGCGTTTATTGACTCGAAATATTTGAAAAAGCATAAACTAAAAAAGCATGCAACTAACAATGTGGATTGGAGTAAGGCTTGA
- Protein Sequence
- METWTDLCRCCLSANTEVSLLDKEQNISQRFLEVTTVEVKLDDGLPQKLCGECYSSMNMAYQFRKQCIKMDTELKTQLNTLLSQCDQSNIDNFENAAEMGEEDSDVAFANDPMKQLEAVIKKEPMDSDDDFYYVLVIDNPKDKENADEQHSATAKKATGLNNAKIKSEILDSNDDKSDLTNYNIQISPGFSQNKEILGVTLNQENTIQTSRNFEKTMDSFLMTNQIPAKVPATILENEEEEQLQEAEEPMQIEETQDSTSQDTQNYQADENTEDEQPITDQNLIKILTTASEDGTILLNSDTMVQYITNDGQLLMNNEEGDQSQEVILCEGDESQFQIVKYDGSELVIEYADDSTIATVLQQDDDSYICECGEQFQDVEELEKHQHQHNPAGEHLCNMCGKGFESSEILTGHMLLHNVPGLLLQCPFCDQVVKRSTLTQHIKYFHNNIKPQCEICTKTFANPNNLKRHMTIHTGVKDFSCDICLKRFHQKITMQTHRLTHMNPLNCPQCELSFKDKETFEEHKVDGVCPKNRAKEELIKTVKQEITTSLGKLLGYACSLCKKMFSIESALEKHIELSHMVDPTELLCSECGEVVSSKAEIEAHMISHNKRKSVKRFECQTCGKGCSSQAMLLMHERVHTNERPFSCQLCPLKFKTKTHLRTHQLTHTREKKFGCSICMKFFALKGNLVVHLRTHTGERPYVCNVCGEAFIDSKYLKKHKLKKHATNNVDWSKA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -