Basic Information

Insect: Lygus lineolaris
Gene Symbol: ZFHX3
Assembly: GCA_030264115.1
Location: JAEMON010000016.1:18287078-18296425[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.21 21 6.6 0.5 1 23 79 102 79 102 0.96

2 15 0.016 1.5 10.2 0.1 2 23 111 133 110 133 0.94

3 15 0.0039 0.38 12.1 2.8 2 22 182 202 182 205 0.91

4 15 0.76 74 4.9 1.2 3 23 219 242 217 242 0.88

5 15 0.012 1.1 10.6 1.7 1 23 260 282 260 282 0.97

6 15 0.0053 0.51 11.7 0.7 2 23 289 311 288 311 0.96

7 15 0.00068 0.066 14.5 3.9 1 23 413 437 413 437 0.92

8 15 0.0081 0.79 11.1 0.6 1 22 457 478 457 481 0.89

9 15 0.0011 0.11 13.8 0.2 1 23 537 561 537 561 0.93

10 15 0.18 17 6.9 0.1 2 21 668 687 667 688 0.94

11 15 0.24 23 6.4 2.0 2 19 829 846 828 851 0.91

12 15 0.00017 0.017 16.3 2.5 1 23 1483 1505 1483 1505 0.99

13 15 0.00055 0.053 14.8 0.8 1 23 1590 1612 1590 1612 0.98

14 15 0.0094 0.92 10.9 0.4 2 23 1796 1818 1795 1818 0.96

15 15 1.3 1.3e+02 4.1 4.0 3 23 2057 2079 2056 2079 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.21	21	6.6	0.5	1	23	79	102	79	102	0.96
2	15	0.016	1.5	10.2	0.1	2	23	111	133	110	133	0.94
3	15	0.0039	0.38	12.1	2.8	2	22	182	202	182	205	0.91
4	15	0.76	74	4.9	1.2	3	23	219	242	217	242	0.88
5	15	0.012	1.1	10.6	1.7	1	23	260	282	260	282	0.97
6	15	0.0053	0.51	11.7	0.7	2	23	289	311	288	311	0.96
7	15	0.00068	0.066	14.5	3.9	1	23	413	437	413	437	0.92
8	15	0.0081	0.79	11.1	0.6	1	22	457	478	457	481	0.89
9	15	0.0011	0.11	13.8	0.2	1	23	537	561	537	561	0.93
10	15	0.18	17	6.9	0.1	2	21	668	687	667	688	0.94
11	15	0.24	23	6.4	2.0	2	19	829	846	828	851	0.91
12	15	0.00017	0.017	16.3	2.5	1	23	1483	1505	1483	1505	0.99
13	15	0.00055	0.053	14.8	0.8	1	23	1590	1612	1590	1612	0.98
14	15	0.0094	0.92	10.9	0.4	2	23	1796	1818	1795	1818	0.96
15	15	1.3	1.3e+02	4.1	4.0	3	23	2057	2079	2056	2079	0.90

Sequence Information

Coding Sequence: ATGTCGGGCTCACCCTGGCATGGCTTGTCAACAGTTCGGGCTCCCAAGGACTCCCGCTCATCGGATTCCCCCGACGGACTCCTTCTTCGGGGACGCAATGCGGGAAGCGAAAAATCTGAGAGTAAGGAGGTTGCTGTAGAAAAGAAGGGTAGCCCATCTCCGTCCTTGCAAATGACATCTCAGCAGGCGGATCAAGCTCAGCATGCCTCTCCTCAGGAGGAGGTTAAAGCTGAATTCTCGTGCAGTCAATGCAATTTCTCTGCCGTGAGCGAAAACAAGCTGCAAGATCACGTTCAAAGCTCTCATCAAACTGAACAAGCTCCTGAAGTCCAATGCCCTTTGTGCCAAGACAGTTTCAGTGACAGGCCATCATTGGAAAGTCATGTCATGCAGATTCATTCTGTTAATTCTGAGGGGTTGCAGAGATTGTTATTGCTGGTAAATCAATCTCATTGGCTCAACCAGAGCAAACCACCCAGCACGTCCGAGAACAAAGAGAAATCTGAAGAAGAGAAAGACGAAGTTGAAGAGACTGATGATGAAAAGTGCCAGACTTGCAACAGGAGCTTCAAAACAATTGATGAACTTTGCTCACATCAGAACGAGACTGGTCACTTAGAACTGAAACAGACCCCCAGTGGGCCTGGCTATCTTTGCTGGAAAAAGGGCTGTAATCAATATTTCCAAACAGCCCATGCTCTTCAAATGCACTTTCGCGAGATTCATGCTCGTGGTGCTGGTCAAAACATGGCTGTTTCTGAGAAACATGTGTATAAATATCGCTGCAATCAATGTAGTCTTGCTTTCAAAACTATGGAGAAACTGCAGCTGCATTCTCAATACCATGTAATCAGGGATGCGACGAAATGTGTTTTGTGTGGAAGGAGCTTCAGGTCTGTTCTTGCACTCCATAAGCACGTAGAGACTGCCCACACGGATTTGTCAGAAGATGAAATGAACGCATATAAGCAGAGTTTATTAAATAACCCCCTGCTTATTGCGGGATTCAGTGGTCAAGTGCTGGATTCGTCAACTAATGAATTGCTCAAGCGAGAATCTATGAAAATGGATGAAGAGTCTGAAGCTGATGAAACGAAAGAAACTGACGAATCTATTGCTCCCCAAGAAGGTGACAACAGTGACGATTCTATCGTGTATAAGGAGCAACAGTTTCTAGAGGACTATCTGAATAGCCAAGCCATTGCTGAAGATTCTTACAACGACCCTGCAAGGAAGTACAAATGCCATAGGTGCAAGGTGGCTTTCACTCGCCAATCTTACCTGACGAGCCATAATAAAACTCTGTTGCATCGGAAAGGCGAGAAATTGTCTTACCCTATGGAAAAGTACTTGGACCCTAATCGTCCTTACAAGTGTGATGTTTGCAAAGAATCATTCACACAAAAGAACATCTTGTTGGTTCATTACAACTCCGTGAGTCATTTGCACAAATTGAAACGAGCTATGCAAGAGCAACAACAgctacaacaaaataataacaacaacaatgctCTCTCGCCTCAAGTCGCTGCCGCTGCAGCGTTGGCAGCTCAGCTAGGTGTGCCTACGCCCTTGAAACAGTCTCAGGATGAAGATGATAAGAAACCCTACAAATGCAATATTTGTAAGGTAGCGTACACTCAGGGTTCTACCTTGGACATCCACATGCGCTCAGTCCTGCATCAAACAAGAGCGTCTAAACTGCAAGACCTCGCAATTACCGGGCAAATCGACCTGAGTAAGCCTTTGATTGAACAGCCAGAGCCTCAAAAGGCTCAGGATCAACATAAAAAGTTGATCCAAGATATTTTGGGTAGTTCGCCCAAACAACTGCTTTCCTCGCCACCGTCCTCTGGTAGCTCTCAGCTCACCGGGTCTTCGCCGAGCTCGTCTGCTCCGCCTCCAGCGGCATCAACTCCTAACTCGGCAACTTCAGTTCCTACTAGCTTAACTAACACATCGAACTCTGTGATAAACACATCACCCAACGCAGGGATGCTCACCTGCGGACGGTGCAACGCTCTTTTTGTCAATCAAGAACAGCTGTCAACGCATCAGCAACTTTATTGCTTGTTCAGCAATCCTATGTCCATGTTCCCGCCTTTGCCTACTCCCCCTTCCTCATCGGCCAACTTGTCCTCACCTCAGCCAAATAGCAGTAAAACCCCACCTCCCATTCCATTGACGCCCATGACTCCTGGCAATGACGAATCATTCCCCAGGATCTCACTTCCTACCAAAAAATCGTCTCAGATGTACAAAACTCTTCTTGAGAGCTTTGGTTTCGATCTTGTCATGCAATTTAATGAAAATCACCAACGAAGACAGaggaaagagaaagaagaagctGAAAAATTGCTTTCTGAAATTTCGTCCACTACTCAACCAGTTGAGGAAGCTATCCCACcagttgaagaagaaaaagagaaagTAGATGTAAAGGTTGAAGAGGAACTTGTTGATCTCCCAGAAGTGGCTAAATCAACGTGCCAACATTGCAATAAAGAGTTTTCTAGTGTGTGGGTACTGAAAGCTCATTGTGAGGAGGTTCATAAAGATTTGGTACCTCTTGATTTCTTGGAAAAGTACGCACAGCAAATCAAATGTGAAATTGAGAAGAAAGTTGTGCCTTCGCCTGTTGTCTCGTCAACAACAGGGACTGAGACAACACCTGAGAAAGAGGAGGACAACAAGGAGGCGATTCAGGCCAAAATTGctcagcagcaacaacaacaacaacaacaacaaacaccACCTAATGCTGAAAATGTTACCGCTCCTTCAACACCAACTGCGTCTTCTACTCCTGCTTCCTCTACTGACTCTTTGCCTGCGACTTTGAGTCACTCGTTGGCTGCCGCAGTGGCTGGCATGAGTGGGAACAATGCTGCTAACATTGCATTGGCTCAACAAATGAACGAAATGCAGGCTGCTCTTAACGTGATGGCTGCATCTCAGATTCAGCAACAACTGCAACAGTTCAACCCTATGATGATGGGTATGGCTGGGCTTGGAATGGGACTCCCTTTGGGTCTGAATATGCCTGCTCTCGCTGCGATGAACCTGCAGCCGCCCCTCGTCCCGATGATGATGCCTCCTCCGTCATTCGACTCGATGGTGGGTATGAGTCAGAACCAATCCAATCTCTTCAATCCTCAGGGAATGGACCCGGCTGCAATGCTTGCTAAGCAGCAAGCCCTCATTCAACAACAGCAGCAAGTGGCTAATGCATCCCAACAAAAACGAGCTAGAACGAGAATAACCGACGATCAACTGAAAATACTGCGAGCACATTTCGATATAAACAATTCCCCTTCGGAAGAACAGATAAATGATATGGCCGCTCAAAGTGGACTCCCACCTAAGGTTATCAAGCACTGGTTTAGAAACACCTTATTCAAAGAAAGGCAACGAAATAAAGACTCTCCCTACAATTTTAATAACCCACCGTCAACCACACTCAATCTTGAGGAGTACGAGAAAACTGGTGAAGCGAAAGTTACTCAATTAGTACCTGATGAGAACAGGGAACAGTCCAAAACACCCACTCAGAAACCATCAGCTTCACCTGTTCCCCCATCTCCCATACCAGCCTCTAATGCACAACCACCTAATATGCAACAACATGCCTTACAACAACAGCAAGAGCAACAGCAACAACAGGAACAACATCAACAACAGTTGCAACAACAAATGCAGGCACAGCAGCAgctgcaacaacaacaacagcagcagcagcaacaacaacagttgcagcagcagcagcaacacCTGCAACAACAAATGATGCATCAAGGATTTGGTCTCACTAACATGATCAAATCAGAACCTAGGGAGCATGAGACTGAACAACACCATCATAGTGATAAACCAGCTCCACAGTTTAACCACCACCAAATGCAATCACCGATGAGTCCAAATGATCGGATGAATCTCTTGGCTACGAGAAACAGTTCACCTGAAAATCTAACGCTTACCTCGATCATTTCTTCTCAGTTGTCGAATATGACGCCAACATCTATGTCTTCGACTCACCCAAACATGTTACCGCCGCCCAAGCTGACCCCGCCTTCTGGTTTTACAACACCAAACCACCAGCAGATGAATATGAGCAACGCTCAGGACTGCTACTCACACGCGATGTTGGGCAACAATGGCGGGAACACGGGCAGCTCCACCACTGGGAAAAGAGCCAACAGAACTCGATTCACAGATTATCAAATCaaagtactccaagagttcttCGAAAACAACGCGTACCCAAAAGACGACGATTTGGAATACCTTTCAAAGCTTCTGAGCCTGAGTCCTAGGGTCATCGTGGTTTGGTTTCAAAATGCCCGTCAAAAGGCTAGAAAAGTATATGAGAATCAACCACCGGTTGAACTGTCCCCTGGGGTTGATGAAACGGGTGCTGGAAGATTTCAACGCACTCCAGGACTGAACTATCAATGTAAGAAGTGTCTGCTAGTGTTCCAAAGGTACTATGAACTTATCCGTCATCAAAAGACTCATTGTTTCAAAGAAGAAGATGCCAAACGATCTGCCCAGGCTCAGGCTGCTGCTGCTCAAATTGCTGCCGTGCTTTCCTCTGAAGACTCGAATTCGAGCACTCACATGGATCAATCAAGTCAGCCTAACCACTCAATAATGACAAGCAGTAATCCTTCAACTCCTGCTGCTCCTGTTACTCCTACTCCATCCCAAAACATGTTTTCCCCTTCTCCAGCTCCAACAACCACCCCAACGCCTGATGGCAAAGACAATTTCCAGTGTGATCACTGTAATCTTGTATTTCCAAGATTTGATCTGTGGCGTGAACACCAGCTTGTTCATATCATGAATCCCAATCTCTTCCCTACATATCCTCCTGATAGCCCATTTGGCATTCTCCAACAGCATGCTCAGCTGCAGCAACAGCAAGCtcagcaacaacaacagcagcaaCAGCAAGCTCAGCAACAACAGCAGTTGCAGCAGCAACAACAGCCACCCCAACAGCAACAGCAAGCTCAACAGCAACACCAACAGGGCCCTCAAACGCCTCAGCGAAAGATGGGCCATGATCTCATGAATCCCAATACCCCCCATCCTTTAATTTCCATGCTTGCTGGGCATAAGAGAAAATTTGACGAATTCGAGGAGAATCATGACAAAGAGGGCGAACAACCAAAGGATAAAAGACTTCGCACTACCATTCTCCCAGAACAGTTGGATTATTTATACCAAAAGTACCAAATTGAAAGCAATCCTTCCAGGAAAATGTTGGAGAACATTGCTCATGAAGTTGGGTTGAAGAAACGCGTTGTTCAAGTTTGGTTCCAGAACACCAGAGCTAGAGAAAGAAAGGGTCAATTCAGAGCTCATTCTCAGGTGATCAACAAACGGTGCCCTTTTTGTCCTGCACTCTTCAAGGTGAAATCCGCTTTGGAGAGTCACTTGACAACAAAACACGCTGATCAGTGTTCTAGAggtgaaataaatattgatgcATTGCCAGATGAAGACACGAATGCAAATGAGAACTCTAGTTCGAATATGCAAGACAAATTCAACAGTATGATGCCTCCAGTGTTCAATCAGTTCAGCAATGACGTTGACGGAACATTGAAAAAGTACTACGAAGAGTCAATGAAACGGTACATGGCGGAAGCTATGAATGGAAAGGACATTTCGGATGTAACTGTCAAAAAAGAGGAAGAGACTGGTGAGACGCCTCTAGATCTAAGCAAACCTGTAGATCTGAGTAGACCTATGAAACTCAGCTTAGAACACATGATGATGGACCAAGGGCCTTTGACTGATCTCAGTGAAAAGAGTCTATGTGATGACGATAGTTTTTCTGAATGTACAGATAACATGGAGGACGAGTCTAATCCAACATCCCCAGCTTCGAGCACGCAAAGTCAACACCAGCATGGGAAGACAAAAAGATTCAGAACACCAATGTCAACGTTGCaagtaaaattaatgaaaacactATTCAATGATTATAAAACGCCTACAATGGCTGAGTGTGAAATGCTGGGTAGGGAGATTGGATTACAAAAAAGGGTTATACAAGTGTGGTTTCAAAACGCCAGGGCAAAAGAGAAGAAGTACAAAGCTGCTATTCAGAGTATAAAACTGGAGTGGCCAGCTGGAGACCAGGAGAGGCCCCCGGAAGACTGTAAGTTCTGTCAATTCAAGTACTCGCACAAGTACTCAGTGCAAGACCACATCTTCACCAAAAAGCACATCGACATGGTGAAAACCTATTTGGAGAGTTCACTGGCCAAAGAGACCGAAGGGGATTTCACCGTGCCACCAGTACCTGGGGCGTCGGGCGAGAGCAATAACAACCACACGACCCAACAGCAGCAGATGGCTCAGCTGCAGATGCTTCAAATGGCCGGCCTGTCGCTTCCTCAGGCGCAGGCGATGGCAATGGCTGTGAAGATCGAGGGCAAAGAGAGCACGCCGGGTCAGCAACCGTCTGCTGAAGACCTCGCGCTCCTCCAGCAGCTCTACGGCGTCACGAACTACCCGCAGGGCTTCATCCACCCCGCCCTCCTCTCTGCTACTGGTGAGTTTCAATTTCACTAA
Protein Sequence: MSGSPWHGLSTVRAPKDSRSSDSPDGLLLRGRNAGSEKSESKEVAVEKKGSPSPSLQMTSQQADQAQHASPQEEVKAEFSCSQCNFSAVSENKLQDHVQSSHQTEQAPEVQCPLCQDSFSDRPSLESHVMQIHSVNSEGLQRLLLLVNQSHWLNQSKPPSTSENKEKSEEEKDEVEETDDEKCQTCNRSFKTIDELCSHQNETGHLELKQTPSGPGYLCWKKGCNQYFQTAHALQMHFREIHARGAGQNMAVSEKHVYKYRCNQCSLAFKTMEKLQLHSQYHVIRDATKCVLCGRSFRSVLALHKHVETAHTDLSEDEMNAYKQSLLNNPLLIAGFSGQVLDSSTNELLKRESMKMDEESEADETKETDESIAPQEGDNSDDSIVYKEQQFLEDYLNSQAIAEDSYNDPARKYKCHRCKVAFTRQSYLTSHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQLQQNNNNNNALSPQVAAAAALAAQLGVPTPLKQSQDEDDKKPYKCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAITGQIDLSKPLIEQPEPQKAQDQHKKLIQDILGSSPKQLLSSPPSSGSSQLTGSSPSSSAPPPAASTPNSATSVPTSLTNTSNSVINTSPNAGMLTCGRCNALFVNQEQLSTHQQLYCLFSNPMSMFPPLPTPPSSSANLSSPQPNSSKTPPPIPLTPMTPGNDESFPRISLPTKKSSQMYKTLLESFGFDLVMQFNENHQRRQRKEKEEAEKLLSEISSTTQPVEEAIPPVEEEKEKVDVKVEEELVDLPEVAKSTCQHCNKEFSSVWVLKAHCEEVHKDLVPLDFLEKYAQQIKCEIEKKVVPSPVVSSTTGTETTPEKEEDNKEAIQAKIAQQQQQQQQQQTPPNAENVTAPSTPTASSTPASSTDSLPATLSHSLAAAVAGMSGNNAANIALAQQMNEMQAALNVMAASQIQQQLQQFNPMMMGMAGLGMGLPLGLNMPALAAMNLQPPLVPMMMPPPSFDSMVGMSQNQSNLFNPQGMDPAAMLAKQQALIQQQQQVANASQQKRARTRITDDQLKILRAHFDINNSPSEEQINDMAAQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTQLVPDENREQSKTPTQKPSASPVPPSPIPASNAQPPNMQQHALQQQQEQQQQQEQHQQQLQQQMQAQQQLQQQQQQQQQQQQLQQQQQHLQQQMMHQGFGLTNMIKSEPREHETEQHHHSDKPAPQFNHHQMQSPMSPNDRMNLLATRNSSPENLTLTSIISSQLSNMTPTSMSSTHPNMLPPPKLTPPSGFTTPNHQQMNMSNAQDCYSHAMLGNNGGNTGSSTTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPPVELSPGVDETGAGRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTHMDQSSQPNHSIMTSSNPSTPAAPVTPTPSQNMFSPSPAPTTTPTPDGKDNFQCDHCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQQQAQQQQQQQQQAQQQQQLQQQQQPPQQQQQAQQQHQQGPQTPQRKMGHDLMNPNTPHPLISMLAGHKRKFDEFEENHDKEGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAHEVGLKKRVVQVWFQNTRARERKGQFRAHSQVINKRCPFCPALFKVKSALESHLTTKHADQCSRGEINIDALPDEDTNANENSSSNMQDKFNSMMPPVFNQFSNDVDGTLKKYYEESMKRYMAEAMNGKDISDVTVKKEEETGETPLDLSKPVDLSRPMKLSLEHMMMDQGPLTDLSEKSLCDDDSFSECTDNMEDESNPTSPASSTQSQHQHGKTKRFRTPMSTLQVKLMKTLFNDYKTPTMAECEMLGREIGLQKRVIQVWFQNARAKEKKYKAAIQSIKLEWPAGDQERPPEDCKFCQFKYSHKYSVQDHIFTKKHIDMVKTYLESSLAKETEGDFTVPPVPGASGESNNNHTTQQQQMAQLQMLQMAGLSLPQAQAMAMAVKIEGKESTPGQQPSAEDLALLQQLYGVTNYPQGFIHPALLSATGEFQFH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00930141;
90% Identity: iTF_00930141;
80% Identity: iTF_00930141;