Basic Information

Gene Symbol
Hinfp
Assembly
GCA_950005105.1
Location
OX465401.1:14296841-14312399[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.026 2.2 9.6 0.6 3 23 1089 1111 1087 1111 0.91
2 8 0.37 31 6.0 0.6 1 23 1126 1150 1126 1150 0.95
3 8 0.0002 0.017 16.3 0.0 3 23 1224 1246 1222 1246 0.93
4 8 0.013 1.1 10.6 3.3 3 22 1254 1273 1252 1273 0.94
5 8 0.01 0.85 10.9 1.0 1 23 1282 1304 1282 1304 0.98
6 8 0.0097 0.8 11.0 0.0 1 23 1308 1331 1308 1331 0.96
7 8 0.0005 0.041 15.1 2.3 1 23 1340 1362 1340 1362 0.96
8 8 4.4 3.6e+02 2.6 1.0 1 23 1400 1427 1400 1427 0.92

Sequence Information

Coding Sequence
ATGTCACTGCTTCGCACACCCCCGAAGGGTGTTGTAACACGTAGTAAACGTGCCACGGAGCAGCTGACTACTAGTAAAAGTGAACAGTTATTCGAAAAGTCAGTGAAAAGTGTTAAAACCGCGTGTTCGTCAGCGGCGGCCCGTAAAAGGCTAGAGTATGAAGCGGCTCAACTTCAAGCACAAATCGACCTCGAATTAGCACAAAAacgtgcacaaatccaaaaGGACTTGCTTATAAAAAAACTGGAAGTCGATATAGCAGACCTACAGGAAGACGACCGTAGCGTTGCGTCGAAAAGTTCGAGAAAAGTCGAGGCGTGGTTCGACAAGCAAGATGGCGGCGCATCCATCGTTAAAAGCGATTGTTCAGAAAATATCTGCCCATTCGACTCAATACCAATGGAGAAGCAACCAAACTTCGTCAGCGAGCACCCGCCACGTGGCGACAGCATCAACCAGTTAACGGAGGCGTTGCACCAAGTACTTGCTACATGTAATGCGCgggaaaataagaataataacaaAGAACTCCTCGCGCGCCTAGCAACATCCAAAGACCTACCGGTGTTCGACGGCGACCCTATGCACTGGCTTCAGTTTAAAGAGTCATATAAGGAGTCGTCACACTCATGTAATTACAGCGATTCAGAAAATATTTGGCGGTTACGAAAGTGCCTACGTGGTGACGCTAAAGAAGCCGTCTCATCGCTCCTCATCGGCCATACAACGCCGCAAAGCATAATCGACACCTTAGAATTACGTTTCGGTCGACCCGAGTGTATAATCCACAAAATATTCACTCAGCTCAAGAGAATACACCCACTTCCGACTGCATACCACACAGAGATCGTGAATTTCTcgattaaagttaaaaattatgtcACAGCTGTTAAATCCATAAAGTTGCAAGAGTACCTACAAAGTCCGGAAACGACAGCATTAATACTTTCAAAGTTACCACCCGCCCTCATCAATAAGTGGGCCGAATACGCCTACGAAGGACGAGACAGACTCATACCTAAACTGGAAATACTATCGGAGTTTTTATACAGAGAAGCAACTATTGTCGCAACCTCAGGCGTGAGTTATATTCAAAGTCAAAACGACGTAAGGAAGAAATACgaccataataatataaaaactcaTTCAGTGTTGGCGTGCACTACTACCTccaataataaatgtatattttgttgtgcCTCTCCGACGCACGCTTTAGAAAAGTGCATCAAATTCAAACGTGCTATGAGACGTGACCGCTGGCAGTTCGTACGTGCTAAACAGCTGTGCTACAAGTGCTTGAGCGCACGCCATAATGAACCCGCCGCGTGCAGTGCTCCCAACTGCAGCGAGTGCGGGCATCCACATCATCATCTCCTTCACTGGACGAAGCCTATCGTGCCTACGTCACCTGCAGCCGCGCGATCGACGCCGGCAGTGGCGTTGGCGGCAACCGCCGGCCAACCCGAGACAGCGCGCCCCGGGGTGCATGCGGCCCGCGCGCACCTATCGACGCCCGACGAGTCGGGCCGTGAGGATACCGTGGCCCACGCCCACACCAGTGTCCCCGCTAGTGTTAGTGAATCATCAGTGCCTAAAGTGTTGTTAAAAATAGTGCCGGTAACCGTTCATGGACCGAAAGACAATATCCACACACACGCATTGCTCGACGACGGTGCCACCGTGACTCTAATATCCGCCGATCTCGCTGATCAGGTGGGACTCCACGGTAAGACAGTCACCATGCGCGCCCGCAGTGCATGGGACTCCGGTGAGCTTGTGTGCCAGACGGAAAACGAGGGTGGATTTGAAATACGAAACTGGGCTAGCAACGTACCAGATGTTCTGGAAAGCGTGCCAAAGGAAGCTTTGAGTGATAGTGTTTGTTGCGCCTTCGATAAAGATCAATCGGAAAGAACACTCGGTTTATTATGGTACCCTGCTAGCGACGAGTTAGGATTCGATTTGACCTTGAAACGTATACCAGTCGATGttCACTCGCAAGCCACAGCTTTTTCCAGTGACATTTCGctgttgaaacaaaataaagaaataaaacgcGATAGTAGACTTCGCGCTTTGACACCCATATTGGATGATACCGGACTTCTACGTGTTGGCGGGAGAATTGGAGCAGCTAAGGAAATAGCGATAGACACAAAATCACCAGTGATCCTGGATGGAAATGACCACGTGGCTCGACTCATTGTCAAGTATTATCACATCCGCGCAGGTCACGGATGCAACGAGTTGGTGGTAAATGAACTGCGTCAAAAATATTGGTTGTTACGTTTACGTCCTACGGTCCGTACAGTTGCGACGCAGTGCTTGTTCTGTCGTATCAGGAAGGCTAATCCTAAGCCGCCACGACTTGGTGACTTGCCTGAAGGTAGACTCACTCATCACCAAAGGCCATTTACCGTCACCGGAGTCGACTTATTTGGACCAATAGAGGTCACAGTGGGAAGATCAAGACCAAAACGCTATGGTGTCTTATTCACGTGCTTGACTGTACGCGCCGTGCATATTGAGATCGTGCCATCTCTCACTGCAGATTCCTTGATAATGGCATTACGTAGAATGGCCGCACGCAGAGGTTGGCCAACGAAGATTTATTCTGATAACGGGACCAATATGCACGGCGCAGAAGTTGAGCTAAAGAAAGCCTATGACGCCATAGACCGAAGTACTGTCATGAACGAAGCCTTGAACAATGGAGTTTCATGGAGCTTCATTCCACCAGCTAGTCCACACATGGGAGGCTCTTGGGAGCGACTTGTGCGCAGTGTCAAGACTGCCCTCAAGGTGGTACTAAAAGAGAGAGCTCCGCACGAAGAGACTCTGATTACTATCCTAGCTGAAGTGGAGAATATTATCAACAGCCGGCCCCTCGGTCATGTTTCTGTGGACCCTCGGGACGACGAAACATTAACGCCGAACCACTTTTTCATTGGTTCGTCGTCTAACTTACCTATCGCAGGAGTGTTTACGGACAAAGATCTTTGTCTCCGTAAGCAATGGCGTATTTCTCAGCGCCTGGCTGACCAATTTTGGGCCAGATGGGTCAAGGAAGTTCTCCCCGATCTAGTGCCGCGCCGAAAATGGAGAGAAGAGGGCGCACAATTGAAGATCGGTGATATGGTAGTAATAGTTGACCCTAACTCCCCCCGTAACTGCTGGCCTAAAGGCATCGTACAGTCCGTGTACCCCGGTAATGACGGACGCTCCCGGCATAAGCTGCGTGTCGCCAACCTGCAAATGGAATGTGAATGGCAGTCCTGTCGCCGCACCTTCGATGATTATGAGCTGTACCAGAAACATGTCCGCAAGCACTCTTCTGACATGCACGTCATTGAAAAAGAATCTGGATCTGAATATGTCTGCCTCTGGGACGTATGCGGTCACAAAACCTCAGACTTTAATGAGATGGTGCGTCACTTGAACTACCACGCTTACCATGGGAAGTTGATGGCTATCGGCTTCAACGGTAGAGCTACGCTGAAGCTAGACCAGTGCAAGAAGGACTCCACCAAACGAAACCAGATACCTATACAAGTTAACGATTATGCTTGCATGTGGTTTGGCTGTGAGGAGAAAACTAAATATAATTCAATGCAGATGTTCCTGGACCACGTACAAGTCCACACAAACTATTCAGATAACTTCCTCTGCTCGTGGGCTGGCTGCGGTGCCGTATTCCCTCGTAAGGAGATGTTGAGGGTCCATGTAAGGACTCATACGGGGGAACGACTGATCGCTTGCTATCATTGTGGACAGCACTTTGCGAATAATAGGAAACTGTGCGATCATTTGAGGAGGCAGAATGTGTACCCAAACTCTCCCTTCGTGTGCTCGCTGTGCGGCACCCGCTGCGCGACGGAGTACCTGCTGGGCGAGCACACGCGGCAGCACGTGTCGACGTACGCGTGCTCGCTGTGCGACATGTCGGCCACGTCGCCGGCCGCGCTCGCCAACCACGTGCGCTACAGGCATCTGGCGCGCGGGGACACGAGGGCGCATGCGTGTCCGCACTGTCAATACAAAGCCATAACAAAATCAGATCTCCGCCAACACATACTTacacataaaaagaaaaagaagaaatgcAAATCTATCAAAAAGGAGATAGACGAATCTGACGAAGAAAATTCAGAATCTGACTGTTATGAAGTTAAAAAGGAGAAATCTGTGAGGAAATACGCCTGTCACTTGTGTCCAGAGAAGAAGATGAAGATATTCTCCAGAGGGAATAGACTGACAACGCACTTGGTGAAGGAACACGGTGCTCAGTGGTCGTTTGGACATAGCAGGTTTAGGTATCAAATGTCCGAAGACGGCATGTACAGACTGACAACCACTCGCTACGAATCCTTAGAAGTCTCTGAAAAAATCATGGATGGCTACAGCAGTCCAAAAGTGCCTTTAACTAGTCtagattttaaactaaaacaggTTGCAGACCCTACCGCGTTCTCGCCTAGATGTTTCGAGATCTCATTGaagaacgatgatgatgatgaaatggaGGTGGATAGGAAACCAGTGATTGAAGATAATGGTGTCGAAATTATGATGTGTGATGTAGACGAAGAAGGGAATATTATAAGCTCTGAGGTTATTGATAATAAGTCTGATCTGATACCGAAGTTGGAGAGGTag
Protein Sequence
MSLLRTPPKGVVTRSKRATEQLTTSKSEQLFEKSVKSVKTACSSAAARKRLEYEAAQLQAQIDLELAQKRAQIQKDLLIKKLEVDIADLQEDDRSVASKSSRKVEAWFDKQDGGASIVKSDCSENICPFDSIPMEKQPNFVSEHPPRGDSINQLTEALHQVLATCNARENKNNNKELLARLATSKDLPVFDGDPMHWLQFKESYKESSHSCNYSDSENIWRLRKCLRGDAKEAVSSLLIGHTTPQSIIDTLELRFGRPECIIHKIFTQLKRIHPLPTAYHTEIVNFSIKVKNYVTAVKSIKLQEYLQSPETTALILSKLPPALINKWAEYAYEGRDRLIPKLEILSEFLYREATIVATSGVSYIQSQNDVRKKYDHNNIKTHSVLACTTTSNNKCIFCCASPTHALEKCIKFKRAMRRDRWQFVRAKQLCYKCLSARHNEPAACSAPNCSECGHPHHHLLHWTKPIVPTSPAAARSTPAVALAATAGQPETARPGVHAARAHLSTPDESGREDTVAHAHTSVPASVSESSVPKVLLKIVPVTVHGPKDNIHTHALLDDGATVTLISADLADQVGLHGKTVTMRARSAWDSGELVCQTENEGGFEIRNWASNVPDVLESVPKEALSDSVCCAFDKDQSERTLGLLWYPASDELGFDLTLKRIPVDVHSQATAFSSDISLLKQNKEIKRDSRLRALTPILDDTGLLRVGGRIGAAKEIAIDTKSPVILDGNDHVARLIVKYYHIRAGHGCNELVVNELRQKYWLLRLRPTVRTVATQCLFCRIRKANPKPPRLGDLPEGRLTHHQRPFTVTGVDLFGPIEVTVGRSRPKRYGVLFTCLTVRAVHIEIVPSLTADSLIMALRRMAARRGWPTKIYSDNGTNMHGAEVELKKAYDAIDRSTVMNEALNNGVSWSFIPPASPHMGGSWERLVRSVKTALKVVLKERAPHEETLITILAEVENIINSRPLGHVSVDPRDDETLTPNHFFIGSSSNLPIAGVFTDKDLCLRKQWRISQRLADQFWARWVKEVLPDLVPRRKWREEGAQLKIGDMVVIVDPNSPRNCWPKGIVQSVYPGNDGRSRHKLRVANLQMECEWQSCRRTFDDYELYQKHVRKHSSDMHVIEKESGSEYVCLWDVCGHKTSDFNEMVRHLNYHAYHGKLMAIGFNGRATLKLDQCKKDSTKRNQIPIQVNDYACMWFGCEEKTKYNSMQMFLDHVQVHTNYSDNFLCSWAGCGAVFPRKEMLRVHVRTHTGERLIACYHCGQHFANNRKLCDHLRRQNVYPNSPFVCSLCGTRCATEYLLGEHTRQHVSTYACSLCDMSATSPAALANHVRYRHLARGDTRAHACPHCQYKAITKSDLRQHILTHKKKKKKCKSIKKEIDESDEENSESDCYEVKKEKSVRKYACHLCPEKKMKIFSRGNRLTTHLVKEHGAQWSFGHSRFRYQMSEDGMYRLTTTRYESLEVSEKIMDGYSSPKVPLTSLDFKLKQVADPTAFSPRCFEISLKNDDDDEMEVDRKPVIEDNGVEIMMCDVDEEGNIISSEVIDNKSDLIPKLER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-