Basic Information

Insect: Lycia hirtaria
Gene Symbol: zfh1
Assembly: GCA_947563715.1
Location: OX387379.1:17834001-17837971[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0091 0.73 11.1 0.3 1 23 40 62 40 62 0.95

2 8 0.00043 0.035 15.2 3.5 1 23 73 95 73 95 0.98

3 8 1.2e-06 9.5e-05 23.3 6.1 1 23 104 126 104 126 0.99

4 8 0.00012 0.0099 16.9 1.0 1 21 132 152 132 153 0.95

5 8 0.00019 0.015 16.4 1.0 1 21 421 441 421 442 0.93

6 8 7.6e-06 0.00061 20.7 1.4 1 23 738 760 738 760 0.94

7 8 5.8e-05 0.0047 18.0 7.2 1 23 766 788 766 788 0.98

8 8 0.0021 0.17 13.0 5.2 1 21 794 814 794 815 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0091	0.73	11.1	0.3	1	23	40	62	40	62	0.95
2	8	0.00043	0.035	15.2	3.5	1	23	73	95	73	95	0.98
3	8	1.2e-06	9.5e-05	23.3	6.1	1	23	104	126	104	126	0.99
4	8	0.00012	0.0099	16.9	1.0	1	21	132	152	132	153	0.95
5	8	0.00019	0.015	16.4	1.0	1	21	421	441	421	442	0.93
6	8	7.6e-06	0.00061	20.7	1.4	1	23	738	760	738	760	0.94
7	8	5.8e-05	0.0047	18.0	7.2	1	23	766	788	766	788	0.98
8	8	0.0021	0.17	13.0	5.2	1	21	794	814	794	815	0.96

Sequence Information

Coding Sequence: ATGTCGCGGCCACGGCCGTTACAACAAATCCGTCCGGTGGCAGGCGGCGGGGTGGAGTCCAAGCCTTGCGAGGAAGAAGAGGAGCGCAGCGGATCCCCGCTGGGCCCCGGTGGACCTTACTCCTGCAGCCAGTGCCGCGGCGCTTACCCCACGCGTGACCAACTTGAGAGACACGAAACCCTGCACGCGCCCAGCACTCAGGTGGATAACCTCAAATATACTTGCAAGATCTGCCACAAGAGCTTTCTAAATGTATACAGGCTGCAACGGCACATGATCAGCCACGATGATAACGCATCACTGCGCAAATACAAATGCAACGATTGTGACAAGGCTTTTAAATTCAAACATCATCTGAAAGAACATCTCCGAATACACAGTGGGGAGAAACCTTTCGAATGTGCCAATTGTGGAAAAAAGTTCTCTCACTCGGGTTCGTATTCCAGCCACATGACTTCTAAGAAGTGTCTCGTTATGAACCTCAAAATGGGAAGAATAAAACCAAATAATCCAGCACTCAACCCAAACCGCAGTCCTTCGCGAAAGCGTGCCAACAACATGGTTGTGTCCCAGTTGAACAACAATATATCACCGAATGGAAACTCTTTTCCTATTCCTATACTGCCGAAATACAACGACGCGGCGGCTTTCTTTGCGACGATGTCCCAGGAAAATAACTTCCATCGTCCAACTTTGGGTCAACCGGGCCTAAATCCTTTTTATATGCCTCCAGGAATGCCCATGAGTCCGGCTAATGGTATAGCACCATACAGTTTTCCTGCTTCTCTGACTTGTCTTTTTGAACAAATAGCTGCTTATCCTCAACGAAAAATTGAAGAGTCAACTAGCCCTAAGCAAAGCAGTACACCTCCCGTTAATCCAGAAGATCTTATAGAAGAGGTTACTGAGGAAGACGATAAGCGATCTGAAGGCAGTGCAGATTTAGTTATGGATATAGAAGATGACGAAGGTGTCACTATAAAAAGTGAGCGAGAGGAACATGACACCAACGTCAAATTACTCTCGCAAAACTACAAATCCGTCCCAAAAAATAGGAGCAATGATGCTCTTAATTATCACTCAGAGTTTGATAAAACATATGATTCATTACGAGCATCTGTAAATAAACAGTTATTTAAAGGAAAGAAAACATCGTCCGTGTTATGTTCGGATAGAGTATGCAGAGTTTCACCATCACCTCATCATGCCAACTCCTGTGAGGGTATAATCGTAAAACAGGAGCCGGAATCCGAAGATACACATAGGTGTTTGAAATGCAATGAAACGTTTTCCAATAAAAGCGATTTATTAGATCACGAAAAAATGCCATGTGGCAATTTCTTTAGAAAGCACGAAAGTTTGGCAGCTCAAGTAGCTGAAACGGTAGCTTTGAATAGAATAGAAGCGGAAATGAAAGCTTCAATACAAAGTGGCGTAAGCGCCAGTGAAGATGAAGACTTTAGCAGAGAGGAGCGTGATGATAAGTTGTCAATACATGACCACGACAGAAAGATCAGAGTGCGCACCGCACTTAGTGAGGAGCAACAGGCCGTATTAAAGGAACATTATGCACTAAATCCTAGACCAAATCGCGAAGAATTTAAAAGAATAGCTCAACAGATTGGCCTCGATAACAGAGTAGTGCAAGTTTGGTTTCAAAACAACAGAGCTAGAGTTCGAAGAATGACACAGACATCGTCGTTGTCCGATCAACCGCTAGATCTGTCCACAAAAAAATCAAACCCTTCGGTGACGTCTAGCCCGTCACCATCTCCACCGTACAGCATTTCAGTAACACATTCCGACTCCGAGGAAGCGGTGAACTTGAGCCAAAAGTCCTCGCGCAGCACTACGCCACATCGACCAAGCTATACGAGCACTTATCCACATTCCAACTGTTCCTCCTCTTCATTTACTGACTTTCGACTTTCACCATCTCCGGGTGAAAGTTTTAATAGTCAACGGCGTCTACTGCCACAAAAAGTAAACCCTATGATGCCTATGGAAAAGTTACTTCATTATAACGACATGGCACGGTCTCCCATTTTAAATATGCATCTATCCGCAGACATCACTCGACAAGGGTCTAGTCCATCATACGATCGTCCTCCATGGGAGGAGATGCAAGCACCCAATGACTACGAAGACGAAGCGACTGTACTTAAGAAGAGCAAGCTCAAAGGAAGCGATTTTAAGGAGGGCGAAGGACAATTCGTCTGTAACCAATGCGACAAGACGTTTGTAAAACAAAGTTCTCTCGCAAGACACAAATATGAACATTCAGGACAACGTCCATACAAATGCGTGGAATGTCCGAAGGCGTTCAAACACAAGCACCATCTGACTGAGCACAAGCGACTCCACACTGGTGAAAAACCGTTTCAATGCAGCAAATGCTACAAGAAGTTCTCGCATTCTGGCTCCTACAGCCAACACATGAACCACCGGTTCGCCATCTGCAAGCCTTACAGAGACTAA
Protein Sequence: MSRPRPLQQIRPVAGGGVESKPCEEEEERSGSPLGPGGPYSCSQCRGAYPTRDQLERHETLHAPSTQVDNLKYTCKICHKSFLNVYRLQRHMISHDDNASLRKYKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPNRSPSRKRANNMVVSQLNNNISPNGNSFPIPILPKYNDAAAFFATMSQENNFHRPTLGQPGLNPFYMPPGMPMSPANGIAPYSFPASLTCLFEQIAAYPQRKIEESTSPKQSSTPPVNPEDLIEEVTEEDDKRSEGSADLVMDIEDDEGVTIKSEREEHDTNVKLLSQNYKSVPKNRSNDALNYHSEFDKTYDSLRASVNKQLFKGKKTSSVLCSDRVCRVSPSPHHANSCEGIIVKQEPESEDTHRCLKCNETFSNKSDLLDHEKMPCGNFFRKHESLAAQVAETVALNRIEAEMKASIQSGVSASEDEDFSREERDDKLSIHDHDRKIRVRTALSEEQQAVLKEHYALNPRPNREEFKRIAQQIGLDNRVVQVWFQNNRARVRRMTQTSSLSDQPLDLSTKKSNPSVTSSPSPSPPYSISVTHSDSEEAVNLSQKSSRSTTPHRPSYTSTYPHSNCSSSSFTDFRLSPSPGESFNSQRRLLPQKVNPMMPMEKLLHYNDMARSPILNMHLSADITRQGSSPSYDRPPWEEMQAPNDYEDEATVLKKSKLKGSDFKEGEGQFVCNQCDKTFVKQSSLARHKYEHSGQRPYKCVECPKAFKHKHHLTEHKRLHTGEKPFQCSKCYKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00281695;
90% Identity: iTF_00032795;
80% Identity: iTF_00926476;