Basic Information

Insect: Lycia hirtaria
Gene Symbol: Zfa
Assembly: GCA_947563715.1
Location: OX387380.1:27906916-27918528[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0012 0.099 13.8 0.8 1 23 275 297 275 297 0.99

2 10 0.00069 0.055 14.6 0.5 1 23 330 353 330 353 0.95

3 10 3.6e-06 0.00029 21.7 1.9 1 23 360 383 360 383 0.96

4 10 0.0032 0.26 12.5 0.2 2 23 390 412 389 412 0.94

5 10 0.00055 0.045 14.9 3.3 1 23 425 447 425 447 0.96

6 10 0.00013 0.011 16.8 0.2 1 22 453 474 453 478 0.94

7 10 0.00024 0.02 16.0 1.7 2 23 487 509 486 509 0.95

8 10 5e-05 0.004 18.2 1.9 1 23 515 538 515 538 0.97

9 10 1.3e-05 0.0011 20.0 0.2 1 23 547 569 547 569 0.98

10 10 0.0034 0.27 12.4 0.1 1 23 575 598 575 598 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0012	0.099	13.8	0.8	1	23	275	297	275	297	0.99
2	10	0.00069	0.055	14.6	0.5	1	23	330	353	330	353	0.95
3	10	3.6e-06	0.00029	21.7	1.9	1	23	360	383	360	383	0.96
4	10	0.0032	0.26	12.5	0.2	2	23	390	412	389	412	0.94
5	10	0.00055	0.045	14.9	3.3	1	23	425	447	425	447	0.96
6	10	0.00013	0.011	16.8	0.2	1	22	453	474	453	478	0.94
7	10	0.00024	0.02	16.0	1.7	2	23	487	509	486	509	0.95
8	10	5e-05	0.004	18.2	1.9	1	23	515	538	515	538	0.97
9	10	1.3e-05	0.0011	20.0	0.2	1	23	547	569	547	569	0.98
10	10	0.0034	0.27	12.4	0.1	1	23	575	598	575	598	0.94

Sequence Information

Coding Sequence: ATGGAAGGAAGCTCTAAATCAGCAGAAGAAACTTATTGTTTGGGGTGTCTCTGTACTCCCAGTGACTACAAAATACATGATTATAAAATACAGTATGCACATTTTTGGGCTATATTTGAGGTAAACACAATAAGGCTTTGCTATTTATGCAAGAGGATAGCTCAACATGCAGAAACATTCATACAAAATGTGCAAAGTAACCAGATATTGCTACAAAATTGTCTTGGAGATCTAGAAACAACCATACAGGAAGCACAATCACAACTACAGCCATCTATAACCCTCTCATACACAACTTTAGACTCAATAATACTACCTGAAAAAGACAAAACAGACTATGAATCTGCTTGCAAAAACTCCAAAATAACAGAATCTGTTGACTACAATAAGGATCAAATTAGCATGAATGAAACGAATGACTTGTATGAAGTCAATGTAAGTAATATAGATGATGCTATGATGGATAAAAGGAATATTAAAGTAGAATTGAAGGTGGAAGAAGCATTAGCCCAATCGGATGGAGGATTTGATGATCAAAATGATGAATTCGAAACCCCATACATAAAAGAAGAAGATGATTTTCCACTGAATTTACTTAAGAAGGAATTAAAAGTAGAAGCTGTCAAAGAGAAAGCTCCGAAGCCACTAGGGAAGAAGAGCAGAATAAATCGAGAAGGGAAGAAAGTAAAAAAGATGGTTAGAAAAAATAAGGAAATAGAACATAATGAGGCATTAGGAATAAAGAAGATATTCATCACCAAAGAAGAATGCATGGAAGAGAGGAAACAGCAGGCATTAGATGAGGTGTACGTGAACTGTGCATACAAGTGTGTAGACTGCTTAAAAGGGTTCAACTACAAGGCTGCCTACGATAACCATTTGAAGAGGCATAGTGAGGAAATGGGCGAGTACAAATGTGATATATGTAAAATCAGAATGGATTCACACGACAAAATGTTGAGCCATAAAAAATGTCACTCAATTCGGTTCCAATGCACCGAGTGCGGTATAGTCCGCACGAGCCGGTCGACCCTGCTGGATCATCACAACGCTATTCACAAGAAAGGAGAGAGTCAGTTTGCTTGTCCGTACTGCCCTAAGTCTTTCAAGCGACAAATGTCACAAAGGAAACATATCCGCTACACGCACCAGAACAAGGAGCGTGTCACGTGCGCCTACTGCCAGAAGAGCTACGCTAACAAAGAAGTTATCAAGACGCACATGATGGCACAGCATCCAAAAGAAGTAGCAGCGATAGAGCCGGCGAAGAAGTACCCATGCAAAGAATGCGGCATGCTGTTCCGCTCAAAAACTCACCTTAGAATGCACAGCTACAAACATTCACTCAGTCGGGACTATTATTGCGTCGAATGTGACAAAGCATTCAAGTCTGAAGCGGTACTGAAGCAACATTTGAAAACTGCGCAGCCGCATATCAACTATTCAGACTTACCGTTATGTTGCGATCAGTGTGATAAGAGATTCGCTATAAAAAGAGATCTCGACCGACACATGAATAGCATACATCTTGAAGTGAAGCCGTTTAAGTGTGACAAGTGTGATAAGGCGTACGTAAGCAACTGGTCCCTCACGGACCACAAGAGGCACATACATGAAGGATACAAGCGGCCGTTACGGTACCCGTGCAGAATTTGTGAGAAAATATTTGACCGTAGTTCGATCCTGAAGGCTCACATCCGCACGCACACCGGCGAGCGGCCGTACCAGTGCGACAAGTGTCCGGCGCAGTTCAGCCAGTCGGGGGTGCTGGCGACACACAACAAGCTGATACACCAGCGGCTCACCAGGGACGGCAGGCCCAAGCAGAATGCGCCCCTCAAGGATATATAG
Protein Sequence: MEGSSKSAEETYCLGCLCTPSDYKIHDYKIQYAHFWAIFEVNTIRLCYLCKRIAQHAETFIQNVQSNQILLQNCLGDLETTIQEAQSQLQPSITLSYTTLDSIILPEKDKTDYESACKNSKITESVDYNKDQISMNETNDLYEVNVSNIDDAMMDKRNIKVELKVEEALAQSDGGFDDQNDEFETPYIKEEDDFPLNLLKKELKVEAVKEKAPKPLGKKSRINREGKKVKKMVRKNKEIEHNEALGIKKIFITKEECMEERKQQALDEVYVNCAYKCVDCLKGFNYKAAYDNHLKRHSEEMGEYKCDICKIRMDSHDKMLSHKKCHSIRFQCTECGIVRTSRSTLLDHHNAIHKKGESQFACPYCPKSFKRQMSQRKHIRYTHQNKERVTCAYCQKSYANKEVIKTHMMAQHPKEVAAIEPAKKYPCKECGMLFRSKTHLRMHSYKHSLSRDYYCVECDKAFKSEAVLKQHLKTAQPHINYSDLPLCCDQCDKRFAIKRDLDRHMNSIHLEVKPFKCDKCDKAYVSNWSLTDHKRHIHEGYKRPLRYPCRICEKIFDRSSILKAHIRTHTGERPYQCDKCPAQFSQSGVLATHNKLIHQRLTRDGRPKQNAPLKDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -