Lhir024672.1
Basic Information
- Insect
- Lycia hirtaria
- Gene Symbol
- ZFX
- Assembly
- GCA_947563715.1
- Location
- OX387385.1:17251074-17255910[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.075 6.1 8.2 0.3 3 23 264 284 263 284 0.98 2 20 0.83 67 4.9 0.4 6 23 296 314 296 314 0.95 3 20 5.2 4.2e+02 2.4 0.2 2 23 325 347 324 347 0.90 4 20 1e-07 8.2e-06 26.6 1.0 2 23 369 390 369 390 0.97 5 20 2e-05 0.0016 19.4 2.2 1 23 396 419 396 419 0.95 6 20 0.15 12 7.2 0.1 1 23 425 447 425 447 0.95 7 20 0.0015 0.12 13.5 0.2 1 23 453 475 453 475 0.98 8 20 9.5e-05 0.0077 17.3 1.7 1 23 610 632 610 632 0.99 9 20 0.021 1.7 9.9 1.8 2 23 639 661 638 661 0.92 10 20 1.4e-05 0.0011 19.9 2.5 3 23 669 689 668 689 0.97 11 20 3.7e-05 0.0029 18.6 0.3 1 23 695 717 695 717 0.95 12 20 0.0039 0.31 12.2 0.9 1 23 723 745 723 745 0.96 13 20 0.91 73 4.8 2.6 1 23 751 773 751 773 0.94 14 20 0.0044 0.35 12.0 4.0 1 23 779 802 779 802 0.96 15 20 6.4 5.2e+02 2.1 0.0 2 23 887 907 887 907 0.86 16 20 3.4e-05 0.0027 18.7 0.1 1 22 915 936 915 938 0.90 17 20 2.6e-05 0.0021 19.1 1.6 1 23 944 966 944 966 0.98 18 20 0.018 1.4 10.1 0.4 1 23 972 994 972 994 0.95 19 20 0.0018 0.15 13.3 0.0 3 23 1001 1021 1000 1021 0.97 20 20 0.00038 0.03 15.4 1.3 1 23 1027 1049 1027 1049 0.98
Sequence Information
- Coding Sequence
- ATGAATATCGGTACAGAACAAGTGTTTATTGTAAATGCTTCTGAACTGAATCAACATATACCGACAACCTTGCAGCGGACTTTTACTATTCCTGGGACAGCATTACAAACTGAAGAAGCACATACAAGCATGTGCCTGCCGCAGTCCATGGAGCCTCCATCTCGCACTCAGATGTGCCGTCTCTGTGCTACCATCACAGAGATGGTGGTGCCCATCTTCCAAGGAGAAGGGCTGCAGAACAACCTCGCCGATAAGATACACCAGCATTTGCCTATACAGGTTTCAGAGGACGACCTCCTGCCCATAGTGTTGTGCTTCCAGTGCAGCAGCACTCTCCTCGCATGGCACGAGCTGGTGGTGTGCTCCCTGCAGGCTGACTCCGTCATGAGGGAGAGGTTCAACCTGTCTCACTCACACCAACAGCAACAGCAGCGACCCATTGTACAATCTAGTCAAACCCAAATCAAAGACGAAAAGTCGCAACCATTGCTTAAAATCATAAAAACTGTACTTTCAAAGTACTTGCATTCCCTTAACATGGACTCTCAAGTGGACCTGGTCTGCCAGAGATGCAACACCAAACCGGCTTTCACTCCTGAAGACTTCTCCGACCATCTGATTACTACGCACCACATGGAAGTTCTCAATGAAAGTGTTGTTAATTGCTTCATAAAAGAACATGTTACATTCGAAGAACCTCTGGTTTCCGATTTAGAATTGGATGAAATACATGATTCTGACACTACAGACTCACCAAATATAAAAACGAACACATTAACTACCCTACTATGTCCGTACTGCGCCAGCGCCTTCTCGTCTACCTCCCGCCTTATCTACCATCTCAGTAAACATATGGAGATATGCATAGATGAAGGCGTGACGTGTTGCGACTTCACTTACAATACTAAGAAAGATTTCGTGTCACATTTACAAGAGAAGCACGTGAACCGACTCATATTTGATACGGAGACTATGTGCAAGAGCTGTGACTTCACCGCGGACACAGCGGAACGATTGCGGGATCACGTCGAAGAGCGTCATGGTGAACTTAGTATTAAGAAAACGACGAAAAAAAGTGCCAAAAATCAGAAATGGATTCCGGCGGTGTGCCCCGAATGCAACAAAACATTTTCGAACAAATACAATATGTTCGCTCACATGAGATCGCACGACGAGGCGACGACGTACGCCTGCCATAGGTGCGACAAACGTTACAGCACGAGAGGCAACCTCCGTCAGCACGTCAAGTTGGTCCACGAGGGCGTCATGTCGCACGTGTGCGGCGCCTGCGGGGAGAGGTTCCCCACGCGAGCGGCGCGCGACGTGCACGCGAGAATACACACGGGAGCCACGCCGTACCGGTGCTCGCTGTGCGCGGCCGCCTTCCGCGCGCGGGACTCGCTGCGGCGGCACCTCGACATGCACCTCGACGTGCGGAACCATGCAAGCGGCCGCCGCGTGCTCGACCTGTCGCCGCGCGGCGCCGGCCTCCACTCCGGAGCCGGCGAGGACGATGCACGCACGCGAGACTCCTCCGACTCGGAAGATCGGCCGCTCGCGACTCTCGCCGAAGGAAAACAGGAGGCGTTTCTTAAATTCTACGAGGCTCTCGTGCGGTACCGGGAGCACGTCGCGGTGGAGCACGGCGCGCGCTCCCGCCCCGAGTCCAGCGAGAGCGGGAGCGAGGAGACCGCGGACGCCGGGGACGGAGGAGTGGAGGCGTACGACGACCTGTCCCACCGCAACCGGCGCCGCTCGCGGCTCGACCCCGCCACGCGGGAGGAAGTCGCGAGCGCGCGCACGCGCACACAGGACGGCAGGACGGTGTACGAGTGCAGCACGTGCGGCAAGCGGCTGAGCTCCGCGCACACGCTGATATACCACCGGCGAATCCACACGGGCGAGCGGCCGTGCGTGTGCCACGTGTGCGGCGCGCAGTTCCGCGCCGCGCCCGGCCTGCAGCGGCACCTGCACGAGACGCACGAGCGCCGGCGGCGCGCCGCGTGCCGCACCTGCCACAGGACGTTCGCCAACGCGCAAAACCTGAAGCAGCACATGAGGATCCACACGGGCGAGCGGCCGTACGCGTGCGCACAATGCGGGAAGACGTTCGCGCAGAGCGGGTCGCTGCATGCGCACCGCGCGCTGCACCGCGAGGAGCGGCCGCACGCGTGCGCGGAGTGCGGCGCCGCCTTCCGGCTGCGGGGGGGACTGCACCGACACCGGCTCCGGCACTCGGGCGAGCGCCCGCACGCGTGCGGACTATGCGCGCGCGCGTTCCGCTCCCGGCACGAGGCGCACGCGCACCGCGTCTCGCACGGGGATGCGCGCCCGCACGCCTGCCACCTCTGTCCCGCTGCGTTCCGCGTGCGTCGAGCGCTGAGACATCACCAGAAGAGGCTGCACTCAGAGGCGCCGTTACCGCCCCCGCCGCCGCCGGAGCGAGCCGCGCTGCAGCCGCCGCTCGGGGAGCTCGCGCCGACCTACTACTCCACCAATCCAGTCGACCGTTCGACCTCCCGTTTGACCGGTGCGCCCGCTTTCAGACTCGATTTAGAGGCAGAGAAGCCGGAGGAGAAGGAAGAGGAGGTAGAAGAGAGTTTACGGGAGACAGACATCCCTCGCACCGTGGTGTCGTCGGGGCGCAGGCGCCGCGCGCGGTGCGGGGTGTGCGGACGGGCGGTGGCGGCGGCGGCGTGGCGGCGGCATGCGCGCGCGCACGCGGGCCCGCGCGGGACGCGCTACAGCTGCCACGAGTGCGGGCGCGCGTTCACAGACGGTGCCAACCTGGCGCGACACGCGGCCGCGCTGCACGCCCCCCGCCGCCCGCACCGCTGCCCGCGCTGCCCGCTCGCGTTCACCCGCGCGGAGCATCTGCGGGAGCACGCGCGCTCGCACTCGCCCGCGCGCGACTTCCTCTGCGACACGTGCGGGCACGCGAGCGGCTCGCAGGCGGCGCTGCGCATGCACCGGCTCACACACGGCCCGCCGAAGCACGGCTGCGTGCTCTGCGGCGCGCGGTTCAAGCGCCTCGGCGAGCTGCGCGCGCACGTCTCCGTGCACTCGGGGGAGAAGCCGCACGAGTGCGCTCTCTGCGCGAGAACGTTCCGACTGCGCGCGCAGCTCACCAGACACGCGAGGACGCATCGAAATGAATTCGCCTAA
- Protein Sequence
- MNIGTEQVFIVNASELNQHIPTTLQRTFTIPGTALQTEEAHTSMCLPQSMEPPSRTQMCRLCATITEMVVPIFQGEGLQNNLADKIHQHLPIQVSEDDLLPIVLCFQCSSTLLAWHELVVCSLQADSVMRERFNLSHSHQQQQQRPIVQSSQTQIKDEKSQPLLKIIKTVLSKYLHSLNMDSQVDLVCQRCNTKPAFTPEDFSDHLITTHHMEVLNESVVNCFIKEHVTFEEPLVSDLELDEIHDSDTTDSPNIKTNTLTTLLCPYCASAFSSTSRLIYHLSKHMEICIDEGVTCCDFTYNTKKDFVSHLQEKHVNRLIFDTETMCKSCDFTADTAERLRDHVEERHGELSIKKTTKKSAKNQKWIPAVCPECNKTFSNKYNMFAHMRSHDEATTYACHRCDKRYSTRGNLRQHVKLVHEGVMSHVCGACGERFPTRAARDVHARIHTGATPYRCSLCAAAFRARDSLRRHLDMHLDVRNHASGRRVLDLSPRGAGLHSGAGEDDARTRDSSDSEDRPLATLAEGKQEAFLKFYEALVRYREHVAVEHGARSRPESSESGSEETADAGDGGVEAYDDLSHRNRRRSRLDPATREEVASARTRTQDGRTVYECSTCGKRLSSAHTLIYHRRIHTGERPCVCHVCGAQFRAAPGLQRHLHETHERRRRAACRTCHRTFANAQNLKQHMRIHTGERPYACAQCGKTFAQSGSLHAHRALHREERPHACAECGAAFRLRGGLHRHRLRHSGERPHACGLCARAFRSRHEAHAHRVSHGDARPHACHLCPAAFRVRRALRHHQKRLHSEAPLPPPPPPERAALQPPLGELAPTYYSTNPVDRSTSRLTGAPAFRLDLEAEKPEEKEEEVEESLRETDIPRTVVSSGRRRRARCGVCGRAVAAAAWRRHARAHAGPRGTRYSCHECGRAFTDGANLARHAAALHAPRRPHRCPRCPLAFTRAEHLREHARSHSPARDFLCDTCGHASGSQAALRMHRLTHGPPKHGCVLCGARFKRLGELRAHVSVHSGEKPHECALCARTFRLRAQLTRHARTHRNEFA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -