Basic Information

Gene Symbol
-
Assembly
GCA_029286615.1
Location
JAGSMQ010000008.1:3774494-3795624[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.029 2.9 9.2 0.1 2 23 266 287 266 287 0.95
2 15 0.015 1.5 10.1 3.4 1 21 292 312 292 316 0.90
3 15 0.0032 0.32 12.2 2.0 2 23 447 469 446 469 0.94
4 15 0.015 1.5 10.1 0.0 1 23 475 497 475 497 0.94
5 15 0.051 5.1 8.4 0.1 1 20 508 527 508 529 0.91
6 15 2.5 2.6e+02 3.1 1.0 1 11 570 580 570 594 0.74
7 15 4.2 4.3e+02 2.4 0.3 1 10 600 609 600 610 0.87
8 15 4.2 4.3e+02 2.4 0.3 1 10 660 669 660 670 0.87
9 15 2.5 2.6e+02 3.1 1.0 1 11 751 761 751 775 0.74
10 15 2.5 2.6e+02 3.1 1.0 1 11 781 791 781 805 0.74
11 15 4.2 4.3e+02 2.4 0.3 1 10 811 820 811 821 0.87
12 15 2.1 2.1e+02 3.3 0.2 1 11 902 912 902 916 0.83
13 15 4.2 4.3e+02 2.4 0.3 1 10 990 999 990 1000 0.87
14 15 2.1 2.1e+02 3.3 0.2 1 11 1020 1030 1020 1034 0.83
15 15 2.9e-05 0.0029 18.6 0.1 2 23 1075 1096 1074 1096 0.97

Sequence Information

Coding Sequence
ATGGAAGTGTTCCTATATAATTCTACTGTTTGCCGATTGTGTGGAGAAGAAAATGATAATGGAAATCTATTGTATTCAAATGAGGAAAATAACCAAAATCTCTGcgaaattattaatacatatttacctattaagGTGTCAGATGATGGTCAACTCCCTCGTACTATTTGTCCTGGTTGTACGATACAGTTGGAAGCTACGGTTGAATTCCTGAACTTAATAATTAACGGTCagAAAGTTATAAGAGAGCTATATCAAAGGGAGAAAGAATACAAGAAGTCCTGTACTCCCTCAAATGAACCTGAGATAATCAcagaaaaaattgtttatgaaattaaTACAAGTGATGGAGTGTACCAGATTGAGCATCCAATTGCTCTACAAGTAGCAGGTTTAGAAAAGCCTAAAAGAAAACGAGGCAGGCCACCAAAAAAACCAAAGAGCCCTGAAGAGTTAGCACAGGAAGCAGCTGTCAAGGTACAGGAAGAAAAGAATAAGAATGAGGGTAATGACAGTGATGAACCTACAGGCAAAAGACGCAGGAAAACTCCAACTAGATTTAAGGAAGTGGTTCAGGGCAAAGAACTTGAAAGAATATTTAGGGAAGAAGGGATGACTGATGGTGAAGAGAGTGACCATGAAAATAAGCAAGCTACAGTAGAACAAGGCCCTAAAGTCCCTGCTTCAAAGGAACCAGAAGTGATTGGGCACATGGAAACTTCAGGAGAGTTAGTTGTTGTATTGAAAGGAAAGGGTCGAGGCCGACCAAAAGGAAGAACGCGCCAGACACGTGAGCAGTGTATGATTTGCGGCATGGTGTTCTCAAGCATAGGAAGATACATGTCGCACATTGCGCAACACGGTCCAGTACTATATCAATGCACCCAATGTGGTGAGACTTTCTCTACTAGGCTGCGATTTTGTGACCATCAAACTGAAACCAACCATGTTGGACAGAACATCCTTCAGTGTAAGGATGTTACCCCCAGCAAACAAGTTGATTTGAAACAAGCCAAAGTCAAGGTAGAAGAAACAATAACAGAAAGTAGTAATGAAAAATCTCAAGATTCAATGGATTTGGCCTCTGTGGATAACCTAGTTAGTAACATACAAGCTACCTCCTTGCCTGAAggtctgcctgaaacactgccTGAAGTTTTACCTGATTTAAACACTCAACCAGTGGAGGAGAAAATTGAAACTCTGAACATAAATAATCGAATAGAGCCTGTAGATGTAAAGTCTGATGAATCTAATAATGTGGTTGAAGAAAATACTGaGCCAGTTGATCCATTAGCAGGTGTTGAGCTTGCAATGACGGAGGAAAAGAACAAGTTGCAATGCAACCACTGtgataaaatatttcgtagcAGACAAAGTAAATCACTTCATATCAAGgCAGTTCATCAGGGAGAGCGGCCGTACAAGTGCGCAGAATGTGGTGCGGCCTTCGGCTACCCGCGCTCGCTCGCTCTGCACTCCGTCTCACATCGACGACATAAAACTGTCTCATCTAAGGGATATGCCTGTGACCTGTGTGGAAAGGTGTTGAACCACCCGTCGTCTGTAGTGTACCACAAGCAGGCGGCACAACGGGAAACGTTCCACGCCGAGCGCACCGCACGCAACTGCGACATGCGGCAAGAGGCCCCCTGTCCACCTCGTCGCAGCACGCCGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCACCTCGTCGCAGCACGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACTCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCTGTCTCTACCTCGTCGCAGCACCGCGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACGCGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACGCCTGCAGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACCGCCTGCACGCGCGGCGACACGCGCCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCCTGTCTCTACCTCGTCGCAGCACTGCCTGCACGCGCGGCGACACGCGCCGAGCGCCCGCACGCCTGCGCACACTGCGGCAAGAGGTACCCTGTCTCTACCTCGTCGCAGCACCGCTTCACGCGGCGACATGCGCCGAGCGCCACGCCTGCGCAACTGCGCAAGAGATTCGCGTCTCGCAGCGCGTGGGCTGCACACGTCCGACGGGAGACGGGCGCGCGGCTGCGCTGCGCCGTGTGCGGGCGCGCCTTCACCGAGCGCGCCGCGCTGCAGCGGCACGCACGCCGCCACGCGCCGCCGATCGCCAGCGCCGGCGACAAGGTACTGCAGCTGCGCCCCGCACCAATAAGTACGTGTGCGGTCGAGCTACCACTCACTGCCGCTCGCCGGCGCCGGCAACAAGGTACTGCAGCTGCGCCCCGCACCAATAAGTACATGTGCGGTCGAGCTACCACCACTGCCGCTCGCCGGCGCCGGCAACAAGGTACTGCAGCTGCGCCCCGCACCAATAAGTACATCTACCACTCACTGCCGCTCGCCGGCGCCGGCAACAAGGTACTGCAGCTGCGCCCCGCACCAATAAGTACATGTGCGGTCGAGCTACCACTCACTGCCGCTCGCCGGCGCCGGCAACAAGGTACTGCAGCTGCGCCCCGCACCAATAAGTACGTGTGCGGTCGAGCTACCACCACTGCCGCTCGCCGGCGCCGGCAACAAGGTACCGCAGCTGCGCCCGCACCAATAAGTACATGTGCGGTCGAGCTACCACTCACTGCCGCTCGCCGGCGCCGGCAACAAGGTACTGCAGCTGCGCCCCGCACCAATAACTACCACTCACTTCCGCTCGCCGGCGCCGGCAACAAGGTACTGCAGCTGCGCCCCGCACCAATAAGTACGTGTGCGGTCGAGCTACCACTCACTTCCGCTCGCCGGCGCCGGCGACAAGGAACTGCAGCTGCGAACCGCACCAATAAGCACACGAAGCAAGTGAGTCTCCTGGTTCCGGACAACCAACAAGTTCCTGCTGAAGTCATCAGCGATCCACAAATATCGTGCGACACAGAGGAGAACGTTATATACATCACTTATGATGTGGACGACTCAGCACCCTCGCTGCATATACTGGGACATGAGCAGACAGTTACTCTTGACGACACTAAAATGTTGTCGTCATGCGAGCTGTATTCGGGTTCATCCCTGCTCGTACCTCAATCTGGACTCGAGCAACTCGAGCTGGAGCAGCTGGATGAGCCCGTAGAACATGAGCAGTTGGAGCAGTTGCAACATGAGCAGCTGCCCGATTCAATTGAGTTGGATGATGAGGAGGAACATTTGCCAGTAACTGATGAACATGGAAATCCACTTCACTTCACAATGCAAGATGGCACCCGGCTGGCTATTACGTCTGCGGATGGCAAATCGTTGCAGGTTATTACGCAAGATGGACAGACAATACCAGTAGAAATTAATAGTTTTGCAGACGAGGAGGAGGTAGACGGTCCTGATACAGTAGTACACCAACTGAACTTACAAAAAAGTGTGGATAGCAATGGTTCCACTCCGATCACTCATTACTACACACTAGTTTAG
Protein Sequence
MEVFLYNSTVCRLCGEENDNGNLLYSNEENNQNLCEIINTYLPIKVSDDGQLPRTICPGCTIQLEATVEFLNLIINGQKVIRELYQREKEYKKSCTPSNEPEIITEKIVYEINTSDGVYQIEHPIALQVAGLEKPKRKRGRPPKKPKSPEELAQEAAVKVQEEKNKNEGNDSDEPTGKRRRKTPTRFKEVVQGKELERIFREEGMTDGEESDHENKQATVEQGPKVPASKEPEVIGHMETSGELVVVLKGKGRGRPKGRTRQTREQCMICGMVFSSIGRYMSHIAQHGPVLYQCTQCGETFSTRLRFCDHQTETNHVGQNILQCKDVTPSKQVDLKQAKVKVEETITESSNEKSQDSMDLASVDNLVSNIQATSLPEGLPETLPEVLPDLNTQPVEEKIETLNINNRIEPVDVKSDESNNVVEENTEPVDPLAGVELAMTEEKNKLQCNHCDKIFRSRQSKSLHIKAVHQGERPYKCAECGAAFGYPRSLALHSVSHRRHKTVSSKGYACDLCGKVLNHPSSVVYHKQAAQRETFHAERTARNCDMRQEAPCPPRRSTPHARRHAPERPHACAHCGKRYPVSTSSQHRLHARRHAPERPHACAHCGKRYPCLTSSQHACTRGDTRPSARTPAHTAARGTPVSTSSQHRLHARRHAPERPHACAHCGKRYPCLYLVAALACTRGDTRPSARTPAHTAARGTLSLPRRSTACTRGDTRPSARTPAHTAARGTPVSTSSQHRLHARRHAPERPHACAHCGKRYPVSTSSQHRLHARRHAPERPHACAHCGKRYPVSTSSQHRLHARRHAPERPHACAHCGKRYPCLYLVAAPPARAATRARAPARLRTLRQEVPLSLPRRSTACTRGDTRPSARTPAHTAARGTPVSTSSQHRLHARRHAPERPHACAHCGKRYPVSTSSQHRARAATRARAPARLRTRARGTPVSTSSQHACSAATRARAPARLHTAARGTPVSTSSQHRLHARRHAPERPHACAHCGKRYPCLYLVAALPARAATRAERPHACAHCGKRYPVSTSSQHRFTRRHAPSATPAQLRKRFASRSAWAAHVRRETGARLRCAVCGRAFTERAALQRHARRHAPPIASAGDKVLQLRPAPISTCAVELPLTAARRRRQQGTAAAPRTNKYMCGRATTTAARRRRQQGTAAAPRTNKYIYHSLPLAGAGNKVLQLRPAPISTCAVELPLTAARRRRQQGTAAAPRTNKYVCGRATTTAARRRRQQGTAAAPAPISTCAVELPLTAARRRRQQGTAAAPRTNNYHSLPLAGAGNKVLQLRPAPISTCAVELPLTSARRRRRQGTAAANRTNKHTKQVSLLVPDNQQVPAEVISDPQISCDTEENVIYITYDVDDSAPSLHILGHEQTVTLDDTKMLSSCELYSGSSLLVPQSGLEQLELEQLDEPVEHEQLEQLQHEQLPDSIELDDEEEHLPVTDEHGNPLHFTMQDGTRLAITSADGKSLQVITQDGQTIPVEINSFADEEEVDGPDTVVHQLNLQKSVDSNGSTPITHYYTLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-