Basic Information

Gene Symbol
-
Assembly
GCA_015586225.1
Location
NW:42680-45537[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.17 7.7 6.9 2.6 1 20 159 178 159 180 0.91
2 14 4.7e-06 0.00022 21.2 0.7 1 23 198 220 198 220 0.99
3 14 4.1e-06 0.00019 21.4 2.8 1 23 307 329 307 329 0.97
4 14 0.43 20 5.6 5.6 1 23 335 357 335 357 0.97
5 14 0.00038 0.018 15.2 0.5 2 23 374 395 373 395 0.96
6 14 0.00026 0.012 15.7 1.9 1 23 402 425 402 425 0.96
7 14 2.4e-05 0.0011 18.9 0.5 2 23 432 453 431 453 0.97
8 14 3.1e-06 0.00014 21.8 0.1 2 23 460 481 459 481 0.96
9 14 4e-07 1.9e-05 24.6 2.6 3 23 489 509 488 509 0.98
10 14 0.0055 0.26 11.5 2.1 1 23 515 537 515 537 0.92
11 14 9.5e-05 0.0045 17.1 2.8 1 23 543 565 543 565 0.97
12 14 3.5e-05 0.0017 18.4 2.6 1 23 571 593 571 593 0.99
13 14 5e-07 2.3e-05 24.3 1.6 1 23 599 621 599 621 0.99
14 14 0.00038 0.018 15.2 0.6 1 23 627 649 627 649 0.96

Sequence Information

Coding Sequence
ATGGAGTATTCATTTAAAACCTGCCTCACTTGCCTCTGCAATTCCGATGAGGCACACAATCTCAATGAGATACTTTTGGAAAACTTAACAATTTTGGAAATACTGTTTAAAATTGTGCCACCCCTATTGGAAAATCAAATCTTAACACTCACACAATGGATATGTATTGATTGTTTGGATAAATTGGTTTTAGCTTATAAGTTTCATCAACAATGTTTGGAATCGGTCAGTTGTTTAAAACAGGATCAGGGAAATGTTTGCAATATCCCCACCAACATGTTTCCATTCGATGAAATTCCTATGGATATTAAAGAAGATCCCGATAGATCAATATATCAAGGTGAAGCTGAGGCAGACAGAATATGCGTTAAGCAGGAGATTCAGGAAAATAGcaatgataaattctatttgttaaaagaaaaatacatgaaaaaatctttaaaACGTAGAAAATTAAAGCAGCCTAAGTGCAATTTTATTTGCCTGCATTGTGCGAAGAGTTTCTGCAGTTTAAAACGTTTGGCGGAgcataaattaaaatgtacaaataaTGCTAAAGAAGATGTTCATATAAATAAGAATtcctataaatataaatgttctCAATGTCCTAAATCGTTTGAAAAACCAACATCCTTCGCAGCACACTATAGAATACATAAAAGACAGATTGagccaaaaagtactaaaagcgACAAAGTTAAGCAGGCTTTGAATGAAGAGGATTGGGAAGAATTAGATGGTTCTATAATTATGGATGAACGAGAATTTTTAACGGAAACTGAGGAGGAGTCTCAAGATGATGAATTaGACAACTCAAAAGAGacaaaagagaaagaaataacAAATACTGATTCTGGAAATAGCATCAACAAGAAAGTAAAgaaAACCAATGGCAGTAATATAAACAAACTTAAATATGCTTGTGATAAATGCGAAAAAGTATTCAAACGTCCTTATTGTCTAACACGTCACAGTAGGGTGCATTCCGCAGATCGACCTCATGAATGTAAAGTTTGTACATATCGCTTTGCCTGTCTTAACACTCTAAAGATTCATATGTTTAAGCATAAAAAAGAATCAGGCCAATTAGACACACCCACACCCCCTAAGGGCATTAAGTGTCCTGTATGCCCACGACGTTGCCGTAATAGAGGAACACTTGCCATGCATCTGTTAGAACACAAacataagaaaaactattattcCTGCATGGTATGTGAGTTCAATTTTAccaccaaaaaaaatttaactactcACACAATCAGCCAACATCCTGAGGTGGAAAAACTTAAATGTGACGAATGTGAAAAGATATTTGTTGTACGCGCCCATCTAGAGGAACACATAAAACGGCATAAAGACCAGGAAAATCTAATATGTTTGATGTGTGATAAAGAATTTCGCAATAATGCGGCTTTAACGGAACACATGCGTATACATAGTACGGAAAATCCCAATCTATGTCCTAAATGTGGTAAAACATTTTGCAGTAAAAGTAGTCTGATTCAACATATGGAACGGCATTTGGATTTGAAGAAATACCAGTGTCCCGAATGTCCCACTCGTTTTAATTGCAAATCGGATGTAAAGAAGCATTTGCCAACGCATTCAAAGGTTAAGGCACATGTCTGCGATATATGTGGGTCAAGTTTTACTCGAGCATGTACCTTAATCAATCACAAAATGACACATTTGGGATTGCGTTCGTTTAAGTGTAGTGAGTGCAGTATGAcTTTCACAGCACGTAAAACTATGTTACGTCACATGCGTACCCATACTGGGGAGAAACCCTACAAATGTAAATATTGTGAACGGGCCTATGCTCAAAGTAACGACTTAACAAAACACTTGAGAACACATATCGGTGAGAATACCTATATGTGTGAACAATGTCCTATGTCGTTTAAATTTTATGGCGAAttaaaaaaccacaaaattgaacattttaaaaaggCGGAAGCGGAAAAATCTAATCtagaacaagaacaacaaaaagaTGCTGCAACataa
Protein Sequence
MEYSFKTCLTCLCNSDEAHNLNEILLENLTILEILFKIVPPLLENQILTLTQWICIDCLDKLVLAYKFHQQCLESVSCLKQDQGNVCNIPTNMFPFDEIPMDIKEDPDRSIYQGEAEADRICVKQEIQENSNDKFYLLKEKYMKKSLKRRKLKQPKCNFICLHCAKSFCSLKRLAEHKLKCTNNAKEDVHINKNSYKYKCSQCPKSFEKPTSFAAHYRIHKRQIEPKSTKSDKVKQALNEEDWEELDGSIIMDEREFLTETEEESQDDELDNSKETKEKEITNTDSGNSINKKVKKTNGSNINKLKYACDKCEKVFKRPYCLTRHSRVHSADRPHECKVCTYRFACLNTLKIHMFKHKKESGQLDTPTPPKGIKCPVCPRRCRNRGTLAMHLLEHKHKKNYYSCMVCEFNFTTKKNLTTHTISQHPEVEKLKCDECEKIFVVRAHLEEHIKRHKDQENLICLMCDKEFRNNAALTEHMRIHSTENPNLCPKCGKTFCSKSSLIQHMERHLDLKKYQCPECPTRFNCKSDVKKHLPTHSKVKAHVCDICGSSFTRACTLINHKMTHLGLRSFKCSECSMTFTARKTMLRHMRTHTGEKPYKCKYCERAYAQSNDLTKHLRTHIGENTYMCEQCPMSFKFYGELKNHKIEHFKKAEAEKSNLEQEQQKDAAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-