Lser002105.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lucilia sericata
Gene Symbol
ZNF526
Assembly
GCA_015586225.1
Location
NW:76393-82197[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.00032 0.015 15.4 0.4 1 23 158 181 158 181 0.97
2 24 0.0035 0.16 12.2 1.1 1 22 187 208 187 210 0.90
3 24 3.9e-08 1.8e-06 27.8 2.5 1 23 213 235 213 235 0.98
4 24 7.2e-06 0.00034 20.6 0.4 1 23 241 265 241 265 0.95
5 24 0.00084 0.039 14.1 3.9 1 23 270 292 270 292 0.97
6 24 0.00022 0.01 15.9 0.3 3 23 300 320 298 320 0.98
7 24 0.00048 0.022 14.9 4.8 1 23 326 348 326 348 0.94
8 24 4.4e-06 0.0002 21.3 0.0 1 23 354 376 354 376 0.98
9 24 0.00028 0.013 15.6 0.3 1 23 463 486 463 486 0.95
10 24 0.00094 0.044 14.0 0.6 2 23 493 515 492 515 0.96
11 24 1.1e-05 0.0005 20.1 2.0 1 23 518 540 518 540 0.97
12 24 2.9e-05 0.0013 18.7 0.7 1 23 546 570 546 570 0.96
13 24 0.0016 0.077 13.2 5.4 1 23 573 595 573 595 0.97
14 24 0.00058 0.027 14.6 1.9 3 20 603 620 601 623 0.94
15 24 0.0064 0.3 11.3 7.5 1 23 629 651 629 651 0.95
16 24 4.4e-06 0.0002 21.3 0.0 1 23 657 679 657 679 0.98
17 24 1.9e-05 0.00089 19.3 0.8 1 23 882 904 882 904 0.98
18 24 0.00035 0.016 15.3 3.5 1 23 909 931 909 931 0.98
19 24 1.7e-05 0.00081 19.4 0.9 1 23 934 956 934 956 0.97
20 24 0.00011 0.0049 16.9 0.7 1 23 962 987 962 987 0.97
21 24 0.0073 0.34 11.2 0.2 1 23 993 1015 993 1015 0.98
22 24 0.048 2.2 8.6 0.2 1 19 1021 1039 1021 1041 0.91
23 24 0.00024 0.011 15.8 4.7 1 23 1049 1071 1049 1071 0.96
24 24 7.5e-05 0.0035 17.4 0.2 1 23 1077 1099 1077 1099 0.98

Sequence Information

Coding Sequence
atgttaaaaaattgttttttaccAGTAAATTATAATAAACCACAAACGCAAACCTGTGGAGAGATAATTTGTGAAAATCTAcaagaatttataattaattgtaaattgtgtaaaatcaaaatatttgagTTTGAAGAATTTGTGCAACATTTTAAGAATGTCCACTTGGACAAGACGTTAATAAATGAAAGCACAACAGAacagaaaatagaaaataaactgcACGAAGACCAGGAGGAAAATTATGAGCGGGTGATTAAATTAGAAATATCCGAGGCTCATGAGCCATTGAAAAATGATGAAAAGTTTACAGCAAACATCGAAAATGAAGAATTCTTATGGGAGGCGGACAATAGTAACTATACGGATGATGACAAGGATGAGGATTATAATACGGAAGATGACGGAGACCCGGAGGAAGATGAGGAACAAAGTAAAAGTATAATGAGAAAGCCGCGTAAACCTAAAGAATTTTCCTgtgaaatttgcaataaaaagtATGCCGACTCTAGACGCTTACAGCTGCATGTGAAAATTGTTCATTTACGCGAAAAACCTTACAAATGCTCTATGTGTGATCAGGCTTTTGCCGAGGAACGTACGCTTAAGAATCATGTGGGTCATAAGCATACCGGTTATGAGTGTCCCGAATGCCACAAGAATTTTTCGACAAATCGCAATTTGAAACGACACATGCTAATACATGTTGATAAAAAAGAATTCATTTGCCAAGAGGATAATTGTGGAAAGGCGTTTGCCACCAAGGGTCAGCTAAAAGATCATCAACGCTATCATACTAGTGAAATGTTTATTTGCGAGGAATGTGGTTATAAGTGCCGGCAACGCGAATCATTAATTGTTCATAAACGCCATCATACGGGAGAGAAGCCATTTGGCTGTAAGCTTTGTGATCGTCGTTTTGGTTCGAAACCTTTACTCAATGAACACATGGCCACGCACGAAACGGAACGTAAACATATTTGTGATGTTTGTGGTAAGAGTTTTAATCGACCTAAGGCTTTATATCATCATAAACATTTACATTTGGGCGTTAAGAAGTTTGTTTGTAAAATCTGTGGGCAGGCCTATGCTCAGGCTGCTGGTCTATCGGCCCACATGCGCAAACATAGAGAAGAGGGTGGCGCCGCCTCTTTTACCACCGAACCTGCGCTACCAcctaataatacaaatattttaaatgtactttatcctAAGGAAATTAAAGAGGAATTACAAACCGAACTtgaaactactgaacaaaatgAACTTGTGACTAATAATGAATGTTCGGAAGATGAAAACGATGTGAGTACTGAGGATGAATATGACGAACACTTAGAGCGGCAGACAGAAATAAGTATAATAAAGCCCCACAAACCCAAAGATTTTGCCTgtgaaatatgtaataaaaaatataccgACTACCGGGGTTTGCAAATACATGTAAAGCTAATACATTTACGTGAAAGACCTTTAAAATGTTCCATGTGCGAGGAGTCTTTTGCCGAAGAACGTTACCTAAAGAGTCACATACAACGTAAACATATCGGTTTTGAATGTCAACAATGTCATcgtgtttttaaaacaaatcccACATTGAAACGTCATTTGGCAGTACACATGGAAACTAGAGAGTTCGTTTGCCAGAAAGAAAATTGTGGCAAAGCTTTTGCCACCCCAACAAGTTTACGGGCACATCATCGCGAtcatgaaatatttatatgtgaaGAATGTGGTTACAAGTGTAAAAGACATGAATCCTTGAGGGAACATAAACGTCAGCATACTGGAGAGAAGCCGTTTGGCTGTGAAGTATGTGGACGAAGTTTTAGTTCGAAAAAATTACTGACCGGACATATGAGTTGTCATGAGACAGTACGTAAACATGTTTGTGATGTTTGCGGGAAAAGTTTTAATCGACATAATGCTCTCTATCATCACAAACATTTGCATTCGGATGTCAAGAAGTTTGTTTGCAAAATATGTGGTCAGGCCTATGCTCAGGCAGCGGGACTATCGGCTCATATGCGTAAACATAGAGAAAATGTCAGTGGGGCTAGTAAAGATGATTTAATGCAAGGATTTTATACTTTAGTTGTGGTacaaaaatgtaaacaaatctcCATCgcaattaatgaaaaattatttcaaaaaatgctgaaaaattgtattttaaccGCGCAGTATAACAATTTCTCGCCTAAAACTTGTGGAGAAATAATATGTCAAAGTGAAACAGCTTTTAGCATAATCTGTAATTTttgtcaaataaaaatattcgaatttcaTGAATTCGTCCAACATTTTCGCACTATACACTGGCCGGAAATTAATGGGACACATAACAAATACAAAACTCTATCAGACAATGAATATCCAGTTACGCAGCCTAAAATTGAAGATGTTAAACAACTAAAACTAGAAGAAAAGGAGCAGGCAAATGATTTTGATATTGAGGAGGAGCCGTTGCAATATAGTGAAGATGACTGGAGGACGGAGTTGGAAATGCAGCAAAGTATTAGTAATAGTGGATTTTCTAATCAAGGGGAAGACAGTTGCAGTGATAGGGAGGAATCCATAGGAATATTAAAGAAGGAATGTGTGGAGAACGAAAAACCCAACCTGAAGAGAAAAAAACATGACTATAAATGCCCTATATGTGCACGTACCTTTATCAAAAAGTCCACATATGAAACACATATAAAAGAGCATAAGATTATGCCTTACAAGTGCACTAAATGCTCACGATCCTTTGACGAAGAGTCGCAACTTATGCAGCATCAACATTTACACGACGGCTATGCTTGTGATATTTGTCAGAAGGTTTTTAAGAAAAGGAATAACTTAGTTTCACATAAAGAAACTCATGTAGAAACGAAAAATTTCAAATGTACTTATGAGAATTGTGAAAAATCGTATGCTGGTCAAAGGCAACTGCAACGTCATATACGTCTGGTGCACATACGGGGAGCCTGTTTTGTTTGTGATGTATGCGGCTCTAGGCAACGTGATAAAATAGCTTTAACCGACCATATGCGTTCGCATACCGGTGAAAGGCCATTTGCCTGCAGTTTATGTGATCGACGTTTTATGACAAAATCTAGACTGGGCGAACATAAAGCCTGTCATGAAACGGAACGTAAGCATGTGTGCGAAGTTTGCGGTAAAAGTTTCAATCGTGCCAAGGCTTTGTATCATCATAGACATTTGCATTTGGATATAAAGAAATTTGTGTGTAAACTTTGCGGTGCTGCTTATGCCCAGTGTGCTGGATTATCTGCTCATATGCGTAAACATAAAGAGGAACAAATTTGCGATGATACAGAAATTACAACAAATAGGACAAATGATTTATTTAACGTATTATTTACTGCTATAAAATAa
Protein Sequence
MLKNCFLPVNYNKPQTQTCGEIICENLQEFIINCKLCKIKIFEFEEFVQHFKNVHLDKTLINESTTEQKIENKLHEDQEENYERVIKLEISEAHEPLKNDEKFTANIENEEFLWEADNSNYTDDDKDEDYNTEDDGDPEEDEEQSKSIMRKPRKPKEFSCEICNKKYADSRRLQLHVKIVHLREKPYKCSMCDQAFAEERTLKNHVGHKHTGYECPECHKNFSTNRNLKRHMLIHVDKKEFICQEDNCGKAFATKGQLKDHQRYHTSEMFICEECGYKCRQRESLIVHKRHHTGEKPFGCKLCDRRFGSKPLLNEHMATHETERKHICDVCGKSFNRPKALYHHKHLHLGVKKFVCKICGQAYAQAAGLSAHMRKHREEGGAASFTTEPALPPNNTNILNVLYPKEIKEELQTELETTEQNELVTNNECSEDENDVSTEDEYDEHLERQTEISIIKPHKPKDFACEICNKKYTDYRGLQIHVKLIHLRERPLKCSMCEESFAEERYLKSHIQRKHIGFECQQCHRVFKTNPTLKRHLAVHMETREFVCQKENCGKAFATPTSLRAHHRDHEIFICEECGYKCKRHESLREHKRQHTGEKPFGCEVCGRSFSSKKLLTGHMSCHETVRKHVCDVCGKSFNRHNALYHHKHLHSDVKKFVCKICGQAYAQAAGLSAHMRKHRENVSGASKDDLMQGFYTLVVVQKCKQISIAINEKLFQKMLKNCILTAQYNNFSPKTCGEIICQSETAFSIICNFCQIKIFEFHEFVQHFRTIHWPEINGTHNKYKTLSDNEYPVTQPKIEDVKQLKLEEKEQANDFDIEEEPLQYSEDDWRTELEMQQSISNSGFSNQGEDSCSDREESIGILKKECVENEKPNLKRKKHDYKCPICARTFIKKSTYETHIKEHKIMPYKCTKCSRSFDEESQLMQHQHLHDGYACDICQKVFKKRNNLVSHKETHVETKNFKCTYENCEKSYAGQRQLQRHIRLVHIRGACFVCDVCGSRQRDKIALTDHMRSHTGERPFACSLCDRRFMTKSRLGEHKACHETERKHVCEVCGKSFNRAKALYHHRHLHLDIKKFVCKLCGAAYAQCAGLSAHMRKHKEEQICDDTEITTNRTNDLFNVLFTAIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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