Lcup003601.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lucilia cuprina
Gene Symbol
-
Assembly
GCA_001187945.1
Location
JRES01000955.1:327884-329401[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.51 34 4.9 0.2 12 23 178 189 169 189 0.88
2 7 9.5 6.3e+02 0.9 0.1 1 23 197 219 197 219 0.92
3 7 0.21 14 6.1 2.2 1 23 225 248 225 248 0.93
4 7 9e-06 0.0006 19.8 2.7 1 23 253 276 253 276 0.93
5 7 9.6e-05 0.0064 16.6 1.7 1 23 282 305 282 305 0.97
6 7 0.0017 0.11 12.6 1.8 3 23 314 335 312 335 0.93
7 7 0.026 1.7 8.9 0.4 1 21 341 361 341 362 0.94

Sequence Information

Coding Sequence
ATGAGTGAAACTGAATCCATTGTTGAAGACACCGAGTACATAGCCGTTGATGCTGCTGACTATGTGGTTTTGGCCGAAGGCGAAGAATTGGAACAGTGTGATGATGGTAGTGTTATTTTTCTGGCCGATGGCCAAGAGTTGATAGAAACAAGTGAGGTGGTTGAGGAACaaaacaatgatgatgatgatgctacCATGATGATAACAGAGGATGGTCAGATGATGATGGTGGAGGAGGTGCATGAGATTATGGATGAGGAAAGTGGCGAACAGCTGGAAGTGTATCAGCACGAAGAGGTGATAGAAGAACCGCCTACACCGCAACAGTTGTGGGCAGAATtggaaaagaaaagaaagagaCTTAATTTGCCACGAGTACCGCGTAAGTTTATGCTGTTTGATGGTATTTGTGCGGAGATTGTAGACTACGATGATGAGGACAGTTCTCCCATAGTAGAATTTTCCATGGTTGCCGATGATCGTGAGGCGGAACGTTTGCCAGTGGAATGTGGCGTTTGCCCAGACATTATGCACAAATCTAAGCTGGAGGCTCATTTAAAGACCCACCTCAAGCCGGGCACTAAGCGCTACAAGTGTATTTACTGCGAAGATGATTTTGTTACACGGGCCTATGCTGCCGGTCATGCTAGAAGGCATATGGGTATTAGGCCATATGTTTGTGTACCTTGTAAAATGTACTATTGCACTAAACAGGATCTTAAAGTGCATGAACAGCGTCGACACTTAGCTAAGGAGCATATTTGCGAACAGTGTGGCAAAACATTTGCCCAAAATACATCCTTACGGCATCATCGTTTACTTGTGCACGAACAGCAGCGTAACTATGAGTGTGAACATTGTGGTAAAAAGTTTCTGCGCAAATATGCCATGACCGAACATGTACGCAACGTGCATTATGGTGATAGGAGGCTGCTCGATTGTCCCTTCTGTGATTTACGCTTTAAGGATACACATAAGTTGGCACAACATCGCAAGGATATGCATTTGAATCAGGGCAAATTTGAATGTCGTGTTTGTGGTTTGGAATTTAATCACATTGATTTCTTTGATGCCCATCGTCGTTCTTTACAATGTCGTAAAAAACTGGGACGTCATTTGTTCCAACAGAAACAGGATAATTATGATGAAATGgatttacagcaacaacaacaagatgaTCAAACAATACTGCCCGATCAATTGCATCAATACCACTATGAAGAACAATTGGATAATGGGCAATTGTATCAACACAATCAGCAGCAGCATGAGGAGGAGGTGGAGGACGAAAATAGTCAACAACAGCTAGATCAACAGAATCAGCAATTCAAACAAGAGCAATTAGAACAGCAAGAAGTTGTGGTCGAAGAGATCACTCATGATATGCACGATGAAATAGTTAATGAACATGAAATAGAAGACCTTGAGGATCAAGAAAATATTGAGGTTGATGAACACGAAAAGGTTAAGGCGGAACAACagcttttatatgaaattgCCGCCATGGATAATGCCTAA
Protein Sequence
MSETESIVEDTEYIAVDAADYVVLAEGEELEQCDDGSVIFLADGQELIETSEVVEEQNNDDDDATMMITEDGQMMMVEEVHEIMDEESGEQLEVYQHEEVIEEPPTPQQLWAELEKKRKRLNLPRVPRKFMLFDGICAEIVDYDDEDSSPIVEFSMVADDREAERLPVECGVCPDIMHKSKLEAHLKTHLKPGTKRYKCIYCEDDFVTRAYAAGHARRHMGIRPYVCVPCKMYYCTKQDLKVHEQRRHLAKEHICEQCGKTFAQNTSLRHHRLLVHEQQRNYECEHCGKKFLRKYAMTEHVRNVHYGDRRLLDCPFCDLRFKDTHKLAQHRKDMHLNQGKFECRVCGLEFNHIDFFDAHRRSLQCRKKLGRHLFQQKQDNYDEMDLQQQQQDDQTILPDQLHQYHYEEQLDNGQLYQHNQQQHEEEVEDENSQQQLDQQNQQFKQEQLEQQEVVVEEITHDMHDEIVNEHEIEDLEDQENIEVDEHEKVKAEQQLLYEIAAMDNA