Basic Information

Insect: Lucilia cuprina
Gene Symbol: -
Assembly: GCA_001187945.1
Location: JRES01000142.1:2257-9931[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.061 4.1 7.8 0.6 1 23 1699 1722 1699 1722 0.91

2 12 1.2 81 3.7 1.0 1 23 1885 1907 1885 1907 0.93

3 12 0.00046 0.031 14.4 2.8 2 23 1910 1931 1910 1931 0.97

4 12 2.2e-05 0.0015 18.6 0.2 3 23 1939 1959 1937 1959 0.98

5 12 4.5e-06 0.0003 20.8 5.8 2 23 1966 1987 1965 1987 0.97

6 12 5.2 3.4e+02 1.7 0.1 5 23 2000 2018 1999 2018 0.96

7 12 0.022 1.5 9.1 0.1 2 23 2057 2077 2056 2077 0.96

8 12 0.00014 0.0095 16.0 0.3 1 19 2083 2101 2083 2105 0.95

9 12 3.1e-06 0.0002 21.3 1.8 1 23 2113 2135 2113 2135 0.99

10 12 0.00011 0.0072 16.4 6.5 1 23 2141 2163 2141 2164 0.96

11 12 0.00065 0.043 14.0 6.4 1 23 2169 2191 2169 2191 0.99

12 12 0.0017 0.11 12.7 6.0 1 23 2197 2219 2197 2220 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.061	4.1	7.8	0.6	1	23	1699	1722	1699	1722	0.91
2	12	1.2	81	3.7	1.0	1	23	1885	1907	1885	1907	0.93
3	12	0.00046	0.031	14.4	2.8	2	23	1910	1931	1910	1931	0.97
4	12	2.2e-05	0.0015	18.6	0.2	3	23	1939	1959	1937	1959	0.98
5	12	4.5e-06	0.0003	20.8	5.8	2	23	1966	1987	1965	1987	0.97
6	12	5.2	3.4e+02	1.7	0.1	5	23	2000	2018	1999	2018	0.96
7	12	0.022	1.5	9.1	0.1	2	23	2057	2077	2056	2077	0.96
8	12	0.00014	0.0095	16.0	0.3	1	19	2083	2101	2083	2105	0.95
9	12	3.1e-06	0.0002	21.3	1.8	1	23	2113	2135	2113	2135	0.99
10	12	0.00011	0.0072	16.4	6.5	1	23	2141	2163	2141	2164	0.96
11	12	0.00065	0.043	14.0	6.4	1	23	2169	2191	2169	2191	0.99
12	12	0.0017	0.11	12.7	6.0	1	23	2197	2219	2197	2220	0.96

Sequence Information

Coding Sequence: ATGACGGAAAATGTTCAGTGTCCAGTATGTACTCTATACCTGCATGCAGGTATGAATCTGTCGGATCACTTGGAGACACATCCGAAAGAACAAGTGATTCGAGCCTTAGTACAAATGACCATATCCAGTACAGGAGTTGGGAGCAATAATACGTTGGCATCTGTGTTGGCTGGAGATAATGgcaagaaaaaacaaactacagAATTAGATGAGAAACCTTTGCCAAACAATAAAGATAAGGAACCTCTTATTGGTAGTGGCAGCAACAGTTGCAGCGCTGCTAGCACAAGTAATTCAGCTAGTAATTGTTCTTTGTCAAACCAAAGTGTTGGTAGTAGTAGTCAAAATTCGAAtaacgttttaaatttttctgctACCAAAATTGAAAGACATCATGAAAATGAGCGggataaaacacaaacaacatcTCCCACATTGCCAGCGAAGACAGTGGTTAAAGCAGAAACGAATTCGGTCGCATTGACCAAGGAAATGGCACCTGCAAACGAGGATATGAATCAATGCTTTTCGAAAAAGAGTGTCAATCAAATGAATTCAACACCAAACTCTACAGTAAATACAAGTCATTCATATCATCCAAATGCTGTAGAATTGGCAAATTCAAACAATATACATACTAGTTTTAATATGTTTGGAGGCAATCCACGTTATGATCCACAACAGCGTAGTGGTATTAACAATCAAAATAATCAATTACCAACACTCCCACACATGCCACCGCCACCACCTCCAGCATCATCGCAAAGTCAACATCACAGTCAACACCAAGAAGTAAGCCGTGGAATTATAGCAGCGAGTTCCAATGGAACATTTCATTCGATACAAACACAACAATTGCCTCCTCCACCGCCCCCACCGCATCATGCCTCGTCGCATATAGGCAATACATCATCTAGCGGACATCGCCAGACCCATATGTTTGCAGCAGGTCAACATCAAACGACACCGTCAAATTCTCATCATCAACAAAGTTTAAAGGTTATATATACACCTAATTTGCCACCACCGCCTCCGCTGCAGctttttactTATCAACCACAAACACATGTGCAACACCATCAGAAACCCCCACCGGCCTATGGCACTGCAATTAGTCAAATACGATCTCAACATAATCAAAATAAGCATCAAGTGACAGGGTCATTGGCAACGCAAAATCAAACATTGCAGCCACATTCAGTTgtacatcaacaacatcatttgcCACAAACATTGCAACACAATTTAAGGATTCAAGTACCACCGCCAACACAACCGATTCCAGCAAAACATTCATATTCGCCAAAAACTAATGCTTTGTCAATTCAACACCATTCAACAACATCTACTAGACATaatcaactacaacaacatcagcaacaacaatctAAAGCTGATGtaacacaacaacagcagcaggaaCAACAGCAGACGCACGCAAATTCTGAAACTACCCAAAATTCTagtaacaacatttttaattcaaatgaaaattctaacaaaacAATTAAGGGTTGTTCAGCTTCAACAACTCAAAATCCAAACGTGCCGTCATATCCCCAAGTTTCAATAAGTCCATCTGCCGCTTCAGCCTCAATAGCTGCTGTAGCCGCCTCTACTTTGGGTAGACACACAAACTCTCCATTTGCTGCATTATTGGCTGCTGCTGCGGGAGCTCCATCCCCTTCCAATGCTTCGTCAGTTTTGCGATACGCTGAGTCACCTGTAGCCCATTATTTAGAACGGGAAAATGGTGATTTCATTGTCCAAGAAACTCCTAAACATATTGTTGAGTGTGTAGAGACTGACAATGGAGAGTTTTCTGTCATTGAACGTATATACCAATCCCCTCCCAGTGTTTTACATATTCATgacgatgatgacgatgatgacgatgaagaCGATGATGATAGTAACAGAGACGACCGTGCTGGAGATGAACAGAAAGAATATTCTGAAAGTAAGTCCAAACAACATGATGTTAACACTACTGATAAATCTAAAGGCGAATCGGAGGATAAGCCAAGGACATCAAAATCTTCCTCCAAAGATGACAGTAAAATGTCTGTTGATACAAGTGGATCTAAAAGGAAGTCTTCACATGACGTTGAAACTCCAGACGATAAGgaaattgttgattttgttaGCATTTCTAGTGATAGCAGCGATGAAGAAGAATTCATATCTCAGGAGGAAAAGGATTATAAAAATACcaccgaaaaaaataaaaataatcacacATCATCTACATCCATATTCTCCATACAAACAGCGTCAACGCTGTCATCAACATCCACATCATCATCCGTATCGCCTTCGTTAACAACTGATAATGGCGATGATCAACAAACAAATTCAATGCCTAACGCTTCATTACATTCTACGTCTAATTCTTCGTCTTCTTCATCGGCGGCAAACACAAACCAAATCCCACAAAATTCAGGAGTAAACAGCAATACTAACACGAGTGCTCGTAAGAAATCATCAAAAAACACTATCACAGTTTTAAGTGATgttcatttgaatttaaatgaatatttagaTTTGGTTGGAAATATTATTGCTTCAAGTAAAGTAGCGGCACAGCGTAAAACATTTGCATCCATAGCTCCTGTACCTTTGGTTAAAATTGAAAAGGAAGAGCCTATGGATGAATATATAACATCAGCAACAAATGAAACCAATTTCAAAACTCCACCACAACATGCAACATCTTTAAAGGCCAACAAACATGAGACTGAAGATATAACTGATAACCCTAGCAGTAGTAATAGTAAACAGACAACAAATAACCATAATGTAATTTTAACCAATGAACTAAAGCACGATGAGCAGGATGAAAAGAAACCTCAGGTCTTTGAAAATGTCACCGAATCGAATACCTCGTCTAGCCTAATGACTATAAATTCCAGTCACGTTACCAGTGTTATACGTATGGCCACAACTAGTCAACACCAATCTcagctacaacaacagcagcttCAGAATCCATCAGAAAGCAATAAAAATTCGACAGAAGCCGAAGATCTTTCACAACCGCAACGTAATGTTCAAACTGTGGCAAGTTCCAAGTCATTAGGACATACACCGTTGGCTCGTAAAGGTCCAAAAAAACTAGTTATTAAGCCAAAATCTTCAAAGACTGAAGTTTTGCCACCTACCAACACCAATGCAAATAAACCAAACCAAATCCAATTAGATGTTGATCAGGAAATGCCAACAACTTCTGCTAAAGCTAGACAAGGGTATACAAAACAAACCTCCCTTGAAGAGGATGCTTTAAATGCCACAGAAGTAAAGGTTAAAAATGAACCCATCACGTCGATAACATATGAAAATCAGCCCCAACATTCTCACTATCAACCAACTAGTTTTAGTATCTTAGAGCAACATCTTAATTCGAAAGAACCTATACTCGAGTTTAAAGAGGAAAAGCCATGTATAACGGAATCTAATTTACCATCGACCTCGATCATCAAAGCAATGAAGatagaaaataatgttaacGATGATGCGCGTGTACTTTATGATTTTGCAAATTCGAAAAAATCGCAAAAGGAAACTACATCTACTTTTCCATCTTCCACATCGCTTTTTTCAAGCAAACAAACTTCTTTAGAGACTTCATCGCTCTTAGATGTACAACAGCAGCACCAGCAACAGGTCACTAAAGAATTGAATAATGAAAATGATACATCATCTTCGTCATCATCAACTTATTCATCACAATCAGCTATGGATGCTACAATGCCCTCGGAGGAACATAACGAAAGTTCAACTACAAATGCCTCGGCTGCAACAACTGGTCAAACTCAACAGCAGCCTAATCAGGTGTATACTgactttcattttaattatctGTATAATAATGGAGGAAGTAACGTGGCAGCTGCTGCTTCTGAACAAACTGACATTAAAAATGCACaacaatttacaacattttatcaaaactccggcaataacaacaatacaatgTTGTTGGAAGACTCATTATCAAGTAAACACTATACGgattatcaacaacaacaacaacaacaaaatcatcaGGTGCAACACCAATTAGCAGGAACATCACACCACCACCAGTGGTTTAACAATAGTAATAACTATCAAACATCCGAACCCAATGTTACACCAGTCACATCAAATCATTCAATTTCTAACATTAATAATGCTTTATCTGTTGATGGCAATAGTGCTGCTTTAGATGGCAGTGAAGttagtaaatatttagatttgGATTCATGTAAACGCGAgcaaaatattgatataattGTTGGTGATCGCTTAACTGTACCTCCACCGCCACCACCATCTTCCTCAACTTCGTGTTCGTTTAATGGTACAACTGAAAATAGTATGGCTGGTATCTGTTCAACTGCAGCCACCTTAAATATAAGAACCGATGAGAAAATGCCAGCTAAAGGTGAAATTTCCGAACAGGAAAGTAATTGCGATATTGACAACTCTTGGAGTCAACCGATGTATGGCGATATTTCTGCACGCTTCTTTAAGACAACATTTCCTGGAATCTTTCCGCAAGACAATGGCTGGAATCATGAGGAATATTTTACTGTACAGGATTTGAGTGCTTCAGCAACTGCACAAGCAACAAATGGGACCAGCAACCGACTAAAAAGTTATGAACCGACCAGTAGTAGCAGtggtaacaacaacagcaatgtaATGCCAATGTTTACCCAAAATTCCAATGATAATTGCAATATTGATGTAATGCCATCAACATCGGCTAAAATACGCAAGAGACGTAAACGTAGTTCTCAAGATGGCAAAACGTCAAATGCCAATGGCAAACGCATGCTGCCAACATCGACAGTAACTTCACAACAAATGATGATGCAACATCAAAATGAGATACCAGGAGTTGAATTTAGTTTCCAACATCAGCAGCTGCAACAACATCCTCAATTACAGCCACAACATTTGCAACAACCCAGTACATCGACAGCATTTTTGGCAGGACCATCAAATGCTAGTACCGCCTTAACATCTGGCTTCATGATGCAACCACAGCAACAATCACAAACCCAGCCACAACAACATCAAACCCAACAAAAACAACGCACAAAAGTTTATGAATGTGGTCATTGTAATGCCAAATATTCTAAACTTAAAGATCGTAATGCTCACATGGTTGATGCCCATAATTATATACGTCAAAATAGGAGATTAGTATGTCCCACAACGGGCCTTGCCACACCATTAACGAATTCAGATATGCAAGATGTTGCACTGCCTACAACAAGCGCAGCTGGCAGCATGTTAGTGCCTCCCTTACAAAATGCTGAGTGTATGGGCGATTATAAGCAGGGCATTGtcaaaatagaaaatgaaaatattcaacGTGATCTAACGGGCGTCGAACCGATCAATGCCAACTTAAGTGCTAAAACTGAAGTAATGGAAGACGACAAACAAAATTTAGCCCTAGTACCCATGAATGCAGCAAATACTGATCCAAATCTTGAATACGACACCAAACCACCAACTAATAGTTTGCCATTATCGCTGACAACTCCCACCAGTAAATTAACAACCCTCTATCGGATGTTGGTCTCGTTTAATATGACAACATTGAAACAAAACCAAAGCCTTTCCGAATTCGatgaaaatcttataaaatcttCAATATTCTTTTGTTACATCTGTCGACAGAATTTCAATTCAGTCAAATTGTACGATGCTCATTTAACCGAACATCCGGCTGAATGTTTTACATGCGGCAAAAAATTCCAGCGATGGAAAAATTTCTCATTGCATTTGAAACGACATTTGGGATGGAAGGAATTTGGTTGCACGGTATGCGATAAGAAATTTGTAGTACGCAGTGCTCTCGTCGAGCATATGCGTATGCATTCAGGACTTTCACCGTTGAAATGTAAAGTTTGTGGCAAACACTTTAAACGTTATTCAAACTTAACACAACATCGTAAACGACATTCGAAACAAATCGTTCGTAGGAAAGAGTATGTTTGTTATTGCGGCGAAGTTTTACCATCAAAAGCACGATTTTTATGGCATAAGGAAACTCATGACTCTAAACCGAAATGTTGTCCCCATTGTTGTGATCGTTTTGTGCATGTGAACTCTTTGCGACGTCACATACGTCTCGCCCATTCAGATAAATTCGATTATACCGAACCGATGGAGTGTCCCATCTGCAAGCAAATATTTGCCAAAGCTTCTATGAAAGCTCACATGGCAACGCATTCCACAGAAACGCAATATGATTGTGCAATTTGCAGCAAGTCCTTCTCAACcaaatggaatttaaaaatcCACTCATGGGTTCATGCAAATCGTACAGCTAAACCCTTTAAATGCGAACATTGTCCCAAGGCATTTGTGCGCGAGGTCGATTTCAAGAATCACATGAATTCCCACAAGCAGATTAAACCCTACACTTGTGAGGTCTGTGGCTGTAAGTTTATACGAAAATACAATTATATGCGCCATAGAAGAGAGCAtcatggaaataaaaaatatacctgTGATTTATGTAAAAAGTCGTTCCATCGTCACTACTATCTAATCGAGCATAGACGCATACATACTGGCGAACGTCCGTTTCAATGTACGATTTGTGGTAAAAGTTCAACAACCAAAACTAATCATAACAAACACCTAAAGATACATCATTCACGTGATCCATTTACGGTGGAAGTATAA
Protein Sequence: MTENVQCPVCTLYLHAGMNLSDHLETHPKEQVIRALVQMTISSTGVGSNNTLASVLAGDNGKKKQTTELDEKPLPNNKDKEPLIGSGSNSCSAASTSNSASNCSLSNQSVGSSSQNSNNVLNFSATKIERHHENERDKTQTTSPTLPAKTVVKAETNSVALTKEMAPANEDMNQCFSKKSVNQMNSTPNSTVNTSHSYHPNAVELANSNNIHTSFNMFGGNPRYDPQQRSGINNQNNQLPTLPHMPPPPPPASSQSQHHSQHQEVSRGIIAASSNGTFHSIQTQQLPPPPPPPHHASSHIGNTSSSGHRQTHMFAAGQHQTTPSNSHHQQSLKVIYTPNLPPPPPLQLFTYQPQTHVQHHQKPPPAYGTAISQIRSQHNQNKHQVTGSLATQNQTLQPHSVVHQQHHLPQTLQHNLRIQVPPPTQPIPAKHSYSPKTNALSIQHHSTTSTRHNQLQQHQQQQSKADVTQQQQQEQQQTHANSETTQNSSNNIFNSNENSNKTIKGCSASTTQNPNVPSYPQVSISPSAASASIAAVAASTLGRHTNSPFAALLAAAAGAPSPSNASSVLRYAESPVAHYLERENGDFIVQETPKHIVECVETDNGEFSVIERIYQSPPSVLHIHDDDDDDDDEDDDDSNRDDRAGDEQKEYSESKSKQHDVNTTDKSKGESEDKPRTSKSSSKDDSKMSVDTSGSKRKSSHDVETPDDKEIVDFVSISSDSSDEEEFISQEEKDYKNTTEKNKNNHTSSTSIFSIQTASTLSSTSTSSSVSPSLTTDNGDDQQTNSMPNASLHSTSNSSSSSSAANTNQIPQNSGVNSNTNTSARKKSSKNTITVLSDVHLNLNEYLDLVGNIIASSKVAAQRKTFASIAPVPLVKIEKEEPMDEYITSATNETNFKTPPQHATSLKANKHETEDITDNPSSSNSKQTTNNHNVILTNELKHDEQDEKKPQVFENVTESNTSSSLMTINSSHVTSVIRMATTSQHQSQLQQQQLQNPSESNKNSTEAEDLSQPQRNVQTVASSKSLGHTPLARKGPKKLVIKPKSSKTEVLPPTNTNANKPNQIQLDVDQEMPTTSAKARQGYTKQTSLEEDALNATEVKVKNEPITSITYENQPQHSHYQPTSFSILEQHLNSKEPILEFKEEKPCITESNLPSTSIIKAMKIENNVNDDARVLYDFANSKKSQKETTSTFPSSTSLFSSKQTSLETSSLLDVQQQHQQQVTKELNNENDTSSSSSSTYSSQSAMDATMPSEEHNESSTTNASAATTGQTQQQPNQVYTDFHFNYLYNNGGSNVAAAASEQTDIKNAQQFTTFYQNSGNNNNTMLLEDSLSSKHYTDYQQQQQQQNHQVQHQLAGTSHHHQWFNNSNNYQTSEPNVTPVTSNHSISNINNALSVDGNSAALDGSEVSKYLDLDSCKREQNIDIIVGDRLTVPPPPPPSSSTSCSFNGTTENSMAGICSTAATLNIRTDEKMPAKGEISEQESNCDIDNSWSQPMYGDISARFFKTTFPGIFPQDNGWNHEEYFTVQDLSASATAQATNGTSNRLKSYEPTSSSSGNNNSNVMPMFTQNSNDNCNIDVMPSTSAKIRKRRKRSSQDGKTSNANGKRMLPTSTVTSQQMMMQHQNEIPGVEFSFQHQQLQQHPQLQPQHLQQPSTSTAFLAGPSNASTALTSGFMMQPQQQSQTQPQQHQTQQKQRTKVYECGHCNAKYSKLKDRNAHMVDAHNYIRQNRRLVCPTTGLATPLTNSDMQDVALPTTSAAGSMLVPPLQNAECMGDYKQGIVKIENENIQRDLTGVEPINANLSAKTEVMEDDKQNLALVPMNAANTDPNLEYDTKPPTNSLPLSLTTPTSKLTTLYRMLVSFNMTTLKQNQSLSEFDENLIKSSIFFCYICRQNFNSVKLYDAHLTEHPAECFTCGKKFQRWKNFSLHLKRHLGWKEFGCTVCDKKFVVRSALVEHMRMHSGLSPLKCKVCGKHFKRYSNLTQHRKRHSKQIVRRKEYVCYCGEVLPSKARFLWHKETHDSKPKCCPHCCDRFVHVNSLRRHIRLAHSDKFDYTEPMECPICKQIFAKASMKAHMATHSTETQYDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEHCPKAFVREVDFKNHMNSHKQIKPYTCEVCGCKFIRKYNYMRHRREHHGNKKYTCDLCKKSFHRHYYLIEHRRIHTGERPFQCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00922372;
90% Identity: iTF_00921620;
80% Identity: iTF_00921620;