Basic Information

Insect: Lucilia cuprina
Gene Symbol: wek
Assembly: GCA_001187945.1
Location: JRES01000933.1:1082854-1085648[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00044 0.029 14.5 1.4 2 23 286 308 285 308 0.96

2 8 0.0012 0.081 13.1 0.0 2 23 318 339 317 339 0.96

3 8 1.8e-05 0.0012 18.9 0.4 2 23 349 371 348 371 0.96

4 8 8.5e-07 5.7e-05 23.0 0.2 1 23 377 399 377 399 0.97

5 8 8e-06 0.00053 20.0 2.5 1 23 405 427 405 427 0.98

6 8 0.0006 0.04 14.1 0.7 1 23 432 454 432 454 0.96

7 8 4e-07 2.7e-05 24.1 1.7 1 23 460 482 460 482 0.97

8 8 0.0011 0.074 13.2 3.5 1 23 488 511 488 511 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00044	0.029	14.5	1.4	2	23	286	308	285	308	0.96
2	8	0.0012	0.081	13.1	0.0	2	23	318	339	317	339	0.96
3	8	1.8e-05	0.0012	18.9	0.4	2	23	349	371	348	371	0.96
4	8	8.5e-07	5.7e-05	23.0	0.2	1	23	377	399	377	399	0.97
5	8	8e-06	0.00053	20.0	2.5	1	23	405	427	405	427	0.98
6	8	0.0006	0.04	14.1	0.7	1	23	432	454	432	454	0.96
7	8	4e-07	2.7e-05	24.1	1.7	1	23	460	482	460	482	0.97
8	8	0.0011	0.074	13.2	3.5	1	23	488	511	488	511	0.98

Sequence Information

Coding Sequence: atgcaGTCAACATTTGCTACTCCCTCAATAGAGGATTCCTTACCTAACTGTTGGATCAACTGGTGTCGTTTGTGTGCCAAGGAGGATCCAAAtcataatataaactttttatatgtaaatgatCATAATGTAGATATGGAAAATAAGGAATTAAGTCTGCAGGAGGCATTGGCCAAATATTTTTGGGTGCAGACTTCTCTGGATGATGTTTTACCCAAAATGTTATGTACAAATTGTTTATCTCTAGTCTCTTCCATGATAAACTTTAATGAACGTGTAGAAAGGGTCCAACTTATGTATTTACATTTGGCCGAAAGTCAAGCCAAGGTTTTAGATCTAAATGCAATACGTTTAAAATTTGATGTTACCGAAACGGAAAGAGATAATTGGTTTTTAAGGTATTTTCCAACACATAAACCAGAAAAGACCACAATAGATAAAGCTTTGCTAACTTCTGAagaggaaaattttaaagtacaaATTAAACAGGAAAATGGAGAAAAATTCTTAGCCATGGATTATGATAACTATATGGAAGAAGATACAGATCTAGAAAAAGAGGAAATAATATTTGATAAGATTACACCTGAATCTTTAGAGgaagatgatgaagaagatCCTTTTCAAGCTAATGATAAAGAAACAACATTTGGGCAAAATGATTCTTCAGAAGAAGACGAAGAAGATAAAGAAGAACCTGCTACAGAATTATGCTCCCTTAGAAATCAGGAACAATCACCAAATTCCTcattagaaaaaactaaaatgaaaagaaaaagaaaaaaacttaaacaattttctgtGGGAGattacaagaaaaacaaaaccaatataAAAGACTTTAAACTGGAATCCAAGTGTAAAGAATGTGGtgaaaattttaccaaatataTGCTATATCGCGATcacatgcaacaacaacataatcatAGCCGTAGCAATAAACATTGGCCGTGTCCGGTTTGCGATAAAGTTCTATTAAGTCTATTCAATCTGGAAAGACATGTACGTATACATGTGCCATTGgaagtaagaaaaaatataaaatgtcctGAATGTGATAATCGTTATACATCGAATGCCCAGTTGGAAACTCATATTCGGTATAAGCATAAAAATGAGAAACCATTTATATGTGAAGAATGTGGTTTGAGTCTAAGGACCAATTCCAATCTGAGACAGCACATGCTGATACATACCGATGTGGCGCCGTTCGAGTGTGAagtttgtaaaaagaaattcaaaaataaaacaagattaaaGaCTCACATGGATATTCATAGTCCCAACAAACATGTATGCAATATATGTGGTTTACAACTGAATTCTAAAGCCACCTTAAATCGTCATTTCCTAGTGCATTCCGATGAAATGCAGCATAAATGTGACTACTGTGGCAAAGCTTTTAAAAGAGCTAAAGCTTTGAAAAATCATTTGCTATTACACACCGGCCTCAAGCCATATTCCTGTGATTTTTGTGATCGTACATTTGCCAATGGTTCGAACTGTCGAAGTCATATGAAAAAACTCCATCCAGAAGAATTGGCGGTACTAGAAGCATCAGGCAATAAGACACATAcgaaaaatataccaaaattgGAAACATTAAAAGCAGTAACCAAGGCAGCCGACAATCTAACACCAGTGGTTACTAAATTTAGTGGTTGCTTTGCTTTTGGTAAAAAGCCTAAAAATCTTGCCGCACTTGATgccaaacaaacacaaaaatcttcccaaaaactaaaaaaacctGCACTCAACCaacttaataataacaataatggcGAACAACTGGCCATGGCCTCACCTTCTTCAACACCCTTAGATTTACAATGTATACCGCTGGCCGGTAATACTACAGCTTCTTCCAATTGTCTCACTGATGCCAAAAATCTTGAAAATGACTTCAACACTACCTCtccttcaacaacaacaacaacaactcccATACcaaattttgataatatttatcaacatttaatgaaacaaaatcaaatagatCTACAAATTAAACGCTCCCAAACACAACACTCACCCCAACCATCTCTTAGTAATGTTAGTACATCACAACACAATACATTTTATCAACAAACTCCTAATGATATTATCAATCATTCTATAAAGCCAACACCAGCTAACAATGATTTGCTACACAGTCCGAATAGTCATCATAGCTCAATGACATCTAACTTAACACATGAGGATCATTCTAATGCCTCATCTATACAGGCTAATTTTTATGGATCAATAAGAACAGCTCTACCACCGGGTAATtttatgtaa
Protein Sequence: MQSTFATPSIEDSLPNCWINWCRLCAKEDPNHNINFLYVNDHNVDMENKELSLQEALAKYFWVQTSLDDVLPKMLCTNCLSLVSSMINFNERVERVQLMYLHLAESQAKVLDLNAIRLKFDVTETERDNWFLRYFPTHKPEKTTIDKALLTSEEENFKVQIKQENGEKFLAMDYDNYMEEDTDLEKEEIIFDKITPESLEEDDEEDPFQANDKETTFGQNDSSEEDEEDKEEPATELCSLRNQEQSPNSSLEKTKMKRKRKKLKQFSVGDYKKNKTNIKDFKLESKCKECGENFTKYMLYRDHMQQQHNHSRSNKHWPCPVCDKVLLSLFNLERHVRIHVPLEVRKNIKCPECDNRYTSNAQLETHIRYKHKNEKPFICEECGLSLRTNSNLRQHMLIHTDVAPFECEVCKKKFKNKTRLKTHMDIHSPNKHVCNICGLQLNSKATLNRHFLVHSDEMQHKCDYCGKAFKRAKALKNHLLLHTGLKPYSCDFCDRTFANGSNCRSHMKKLHPEELAVLEASGNKTHTKNIPKLETLKAVTKAADNLTPVVTKFSGCFAFGKKPKNLAALDAKQTQKSSQKLKKPALNQLNNNNNGEQLAMASPSSTPLDLQCIPLAGNTTASSNCLTDAKNLENDFNTTSPSTTTTTTPIPNFDNIYQHLMKQNQIDLQIKRSQTQHSPQPSLSNVSTSQHNTFYQQTPNDIINHSIKPTPANNDLLHSPNSHHSSMTSNLTHEDHSNASSIQANFYGSIRTALPPGNFM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00922319;
90% Identity: -
80% Identity: -