Lcup003563.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lucilia cuprina
Gene Symbol
-
Assembly
GCA_001187945.1
Location
JRES01000955.1:232338-245012[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 43 9 6e+02 0.9 0.2 3 23 116 137 115 137 0.88
2 43 0.00046 0.03 14.4 10.4 1 23 140 163 140 163 0.96
3 43 0.0018 0.12 12.6 0.1 2 23 180 203 179 203 0.93
4 43 0.0057 0.38 11.0 1.2 1 23 209 233 209 233 0.97
5 43 0.00045 0.03 14.5 0.4 1 23 239 263 239 263 0.96
6 43 0.0067 0.45 10.8 1.4 1 23 269 291 269 291 0.98
7 43 3.1e-05 0.0021 18.1 1.7 1 23 297 319 297 319 0.99
8 43 0.011 0.71 10.1 0.2 1 23 325 347 325 347 0.97
9 43 3.6e-05 0.0024 17.9 1.0 1 23 353 376 353 376 0.98
10 43 2.6 1.7e+02 2.6 0.2 2 20 537 555 537 559 0.83
11 43 0.11 7.4 6.9 10.7 1 23 562 585 562 585 0.96
12 43 0.0011 0.072 13.3 0.7 3 23 600 622 599 622 0.92
13 43 0.002 0.14 12.4 0.6 1 23 628 652 628 652 0.97
14 43 0.097 6.5 7.1 0.5 1 23 658 682 658 682 0.97
15 43 0.00033 0.022 14.9 2.5 1 23 688 710 688 710 0.98
16 43 1.2e-05 0.00081 19.4 0.5 1 23 716 738 716 738 0.98
17 43 0.0021 0.14 12.4 0.9 1 23 744 766 744 766 0.96
18 43 2.3e-05 0.0015 18.5 0.2 1 21 772 792 772 793 0.97
19 43 0.0008 0.054 13.7 10.7 1 23 960 983 960 983 0.96
20 43 0.00056 0.037 14.2 0.2 3 23 998 1020 996 1020 0.92
21 43 0.0033 0.22 11.8 0.5 1 23 1026 1050 1026 1050 0.97
22 43 0.05 3.3 8.0 0.2 1 23 1056 1080 1056 1080 0.96
23 43 2.8e-05 0.0019 18.3 2.3 1 23 1086 1108 1086 1108 0.98
24 43 2.7e-05 0.0018 18.3 4.1 1 23 1114 1136 1114 1136 0.98
25 43 0.00036 0.024 14.8 3.3 1 23 1142 1164 1142 1164 0.97
26 43 9.6e-05 0.0064 16.6 1.1 1 23 1170 1193 1170 1193 0.97
27 43 0.0027 0.18 12.0 2.1 1 23 1387 1410 1387 1410 0.94
28 43 2.2e-05 0.0015 18.6 4.2 1 23 1413 1435 1413 1435 0.99
29 43 0.00085 0.057 13.6 0.1 1 23 1441 1465 1441 1465 0.91
30 43 0.033 2.2 8.6 2.1 1 23 1471 1495 1471 1495 0.95
31 43 0.00015 0.01 15.9 2.2 1 23 1501 1523 1501 1523 0.98
32 43 5.2e-06 0.00035 20.5 0.3 1 23 1529 1551 1529 1551 0.98
33 43 0.069 4.6 7.6 0.2 1 23 1557 1579 1557 1579 0.93
34 43 0.00026 0.018 15.2 1.6 1 23 1585 1608 1585 1608 0.97
35 43 0.6 40 4.6 1.3 2 23 1668 1690 1667 1690 0.92
36 43 5.6e-06 0.00037 20.5 1.3 1 23 1811 1834 1811 1834 0.96
37 43 0.0097 0.65 10.3 0.1 2 22 1851 1871 1850 1873 0.88
38 43 0.009 0.6 10.4 1.5 1 19 1876 1894 1876 1896 0.90
39 43 1.9e-05 0.0012 18.8 4.6 1 23 1904 1928 1904 1928 0.97
40 43 0.13 8.8 6.7 5.1 1 23 1934 1958 1934 1958 0.97
41 43 0.0031 0.21 11.8 1.3 2 23 1965 1986 1964 1986 0.96
42 43 0.00012 0.0083 16.2 0.1 3 23 1994 2014 1992 2014 0.96
43 43 0.0025 0.17 12.1 3.0 1 21 2020 2040 2020 2041 0.93

Sequence Information

Coding Sequence
atgtatcacatacaaaatttacattttgaatacataagaaaagaagaatgcaatgaattttataaaaatgatgaaTTTAAGGAAGAAAAATATGATGAAGTGTCGGAATCATTGAATAGTTGTGATGTTTTATATGATTGCAAGGTTAATGATGATGCAGTTAATAGTTCTGAAGAAGAAACAATAAAGGTGTTGGAAGTCAGAcctaaatttagcaaaataacTAGTAGCACTAAAGAAACTAATATAGAGGAAGAGAATCACTTGGAAGAGACGTCAAAACTTTCTACTGTTTATGAAATTGGTGATCCTTTTGCTCCTAATCAAAAATTCGAAGCTTTATTGTGTCCCGATTGCCaggaattattttttcttaaaaaggaaTATGATGAACATGTTGTTAAAGAACACAACGGTCATAAATGCCCCAAATGTGATATGCGTTTTCGACACCGACATCACCTCAGACGGCACTTACAAAATATGCACGAAGATTGCGAGGAAAGGAAACAGAACAAAAGATTAAAACAAAGAATACCCTGCCCTTATGCCGAATGTCCgaaaagttttactttaaagGAATCTCTTAACTATCACCTGGAATTCCATACTATgaaatgtacttttgtatgtaattttgaaaattgcagcAAAAGTTTTCCCACACAACAGCGTTTAGATCAACACCAAGAGAAACATACTATGGCACGTACGTTTGTTTGTGATTTTGATAATTGCAACAAAGCTTTTGCCAATAAAACCCGTTTAAAAGCCCACCAGGATGTACATGCTCTAGCAAAACGATATATTTGTGATGCTTGCGGCTATAGTTGTCGGGCCTCGACTACATTGCGGATTCACAAACGTATGCATACGGGTGAAAGACCTTACACTTGTAAGATATGTGAAAATGCTTTTACCTCGCAGGCCACTCTTCACCTACACATGAATACACATGCCACTATACGTCCATATGTTTGTCAGATTTGTCAGGCTACATTTGCCAATCGTCAGATACTTGAACGGCATGCCTACACGCATGCGGaagagaaattatttaaatgtctaCTATGtgataaagcttttaaacaacCTCATGGTTTAGATGGTCATATGAGACGTTTACACTTGGAACCAAGgccaaaaaaaattgTAACGCCTTACCTGACAAATTCAGAACCTACAACAAAATGTGGGGAAATATTTTgtgatcatttaaaaaatgtcacTATAAGCTGTTCTTTTTGCCAAATTAAACTATTTACTTATCAAGATTTTCTGCTGCACATAGAAAATGaacattttgaaaacataaCGATCGAATCTAATGAATTTAGTGAAAATGAAGAATTAAATGTTGAAAGCAGTGATGATCAGTTCGAAACATTGGAATGctgtgaaattttatatgacTACAAAGAAAATGATGAAGAGAATGATAATAGTTctcaagaagaagaagaagaaaatctGAATGTAACGAATATCGAAACTATAATTAGCAAGACAATAGATGAAGAACAAAATCACTCGAAAGAGTCTTCACAACTTTCAAATATTAGGGAAAGTGATGATGATGTAGCCTcttctaaacaaaaagaaatcgaAACATGTCCAGATTGccaagaaatatttttgcttaaaaaagaatataatcAGCACGTTGTGGAGCAACATAATGGACATAAATGTCCTAAATGCATAATGCGCTTTCGACATCGTCATCACCTTAAACGACACCTACAAAATACACACGACAAGGGAAAAACGAATGTGAGATTTCCGCAAAGAGTTAACTGTCCCCACCCAGATTGTCCAAAAAGTTTTCGTTTTCAAGATGCCCTTAACTATCATCTAGAATTCCATACAATGAAATGTACTTTCGTAtgtgattttgaaaattgcacCAAAGTCTTTCCATCTCAACAGCGTTTAGAGCAGCATCAAGAGAAACACACTACGGCACGGACGTTTGTATGTGATTATGAAAATTGCAACAAAGCTTACCTGAATAAACGTAATCTAGATGAGCACCGGGAGACACATGCCACAGCAAAAAGATATATTTGTGATAATTGCGGTTATAGCTGTAGTAATACTACCACTTTGAAAATTCACAAACGTATACATACGGGCGAAAGACCTTTTCCATGTAAGATATGCGAAAAATCCTTTATCTCTCAGGCCAGACTGTACTTGCATATGAATACACATGCTGACATACGTCCACATGTTTGTCAGATATGTCAGGCCACATTTGCTAATCGGGGTACAATGAAACGGCATTCCCTTATACATTCTGaagagaaattatttaaatgtccGTTATGTGATAAAGCTTTTAAGCAACCAAATGGCTTGCATGGTCATATGAGAGAGTCTAATGAATTTGAAGATAATGAAGAGTTTAATTCTAATGAAATTGAAGACAATGACAATTTAAATTCGAATGAAATTGAAGATAATGAAGATTATAACTCGaatgaaattgaagaaaatgaAGATTATAACTCGaatgaaattgaagaaaatgaAGATTATAACTCGAATGAAGATAACGCAGAGGTTGAGGTGGAAAATAGTGATGTTTTGGAAACATTGGAATgttgtgaaattttatatgacTTAGAAGATAATGGTGGAGAGGAGCAtagttttgaagatgaatcaATGGATGTTGAAACTGTAATTATCGATACAATAGAGAAAGTTGAAGATCACACGGAAGAGCCGTCATTACATTCTCCTAAAAATGAAATAGATGAACCTGACTCTCCTAAACAGAAAAATGCCGAATCTTCAATTTGTCCAGATTGCAAAgagttatttttacttaaaaaagacTATGATCAGCATGTTGTGGAACAACATGGTGGACATAAATGTTCCAAATGCGATATGCGCTTTCGTCATCGACATCACCTTAAACGgcacatacaaaatatacatgACAAGGGTAAAAcgcatattaaatttaaacagagAGTCAACTGCCCTTATCCAGATTGTCcgaaaagttttagttttcaaGAATCACTTAACTATCATCTTGAATTCCATACTATGAAATGTACTTTTGTGTGTGATTTTGAGAATTGTACCAAGGCATTCCCATCTCAACAACGTTTGGAGCAACACCAAGAAAAGCATAATATGACACgaaaatttgtttgtgatttCGAAAATTGCGGCAAAGCTTATCTCAGCAATCAAAGTCTAAAGGCCCACAAGGAGATACATGCTCCAGCAAAAAGGTATATTTGTGATAATTGCGGTTATAGTTGTAGTACCTCTACCGCTTTGAAAATTCACAAACGTACACATACGGGCGAAAGGCCTTTTACTTGTAAGATATGTGAAAAATCTTTCACTTCTCAGGCAACTCTACATTATCATACAAATACACATGTCACCATACGTCCACATGTTTGTGAGATATGTCAGGCTACATTTACTAATCGGCATACAATGAAACGTCATTTACTTATACATTcggaaaagaaattatttaaatgtcagTTATGCgataaagcttttaaacaacCTCAATGCTTGGATGGTCATATGAGAGGTGTACATTGGGAACCCAAaccaaaaaaagtcaaaaattttaaaaatatttcaaattccagcgaaacaacaacaacattCTACCTACCAGCCACTACTACCAAATGTGGTgaaatattttgtcaaaatttcaatgatttctttatttgttgtgCATTTTGCCAAATGAAATCCTTTCAATTTGAGGAATTTCTAcagcatttaaaaaatgtccaTATAAATGATTATCGACAACAAATAGCAAAGGTtgcaaatgaatatttaaatatagagGTAAAGAATGAAAGTTTATTGTGTGAAAAGAAAGGTGATTGTAAAGAGTGGCAGTTGGAAACGCAATCGATGACCGATGATAGTGAAAATGTTCATGATGATGGCAATGATAGCAACGACAGCAGTGAAGAGGAGAAATTTaggattttaaagaaaactaaacgaagagtattaagaaaaagaaacagcAAGCAAAGTCAATCTACGAGTTCAGAGGAATTGGATATACCGGAGAATAATTGCAACTCACCTTTAAATGATTCCTTCAGTAAACAAGCCGATtcaagtaaaaagaaaaaacataaagacTTAGAATACTCTTGCTCGGAATGCACAGAAATTTTTGCACAGAAAAAACATCTTGATCATCATGTTATACAATTGCATAATGGCTACAAATGTCCACAATGTGATAAACGTTTTGGACGCAGTTATCATGTAACATATCACCTTAAAACTcatactatagaaaaaaaattcatatgtcTCATGGAAAATTGTGGTCGTGGTTTTATAGACGAAGATTATCTTAAGCGTCATCTAGAGGTGCATACCATGGAACGTACGTTTATATGTGAATTTGAAAATTGTGGAAAAGCTTTTCAAACCCATAGACGTTTGGCCTCCCATCAGTATAGACATCGTATACCTAAGAAATTTGTTTGCGATATGTGTGGTCATGGTTGTCGTTCTAATACCGAATTGATAACCCATCAACGAGTGCATACGGGAGAGAAACCATTTGTCTGTAAAGTGTGCAGTAAACCTTTCATATCGAAAACAGCTTTAACCGAACATATGATAACACATTCCGAAACTAGACCTCATGTATGCGGCATCTGTCAAGCAGCATTTGCTAATCGTCGTGTGCTAGTACGTCATAGTTTTATACATTCCGAggagaaaacatttaaatgtaaattatgtgAAAGTGCTTTTAAACATCCTAACTCCTTGCAGGGTCATATGCGCAATGTTCATGGTCaagcaaaacacaaaaaagggagagaaaaaaacaacaacagattgAATAAGGTATATAATGATAAATCATTATTGgcaaatatgttgaaattaatgcgcacatttaattttaactctCAACCCAAAACTAAATGTGGAGAAATATTCTGCCACAACACCAACGACTTTACCGTCTACTGTACATTTTGCGAAATGAAATCATTTTCCTTTGAGGATTTTCTAAGACATCTTAAAACTTTACATTTTGCCAGTGAAATGTGTAAAAATGAAAGCACAACATATTGCAACACCAAATTGGAAGCTGAAGAGGACAAAATATACGatactttaataaaatcatataatgATGAAGACCAGACAGATTTCGAAAATACTGCTGCTCTAGATGATAGAGGTTTTGATGTGGATGATGATGCTGATTACTGTGATAATGATAGTTACGATGAACCTTTGgtagtattaaagaaaaaacttgttaaGCAAAGAAGCAAAAGGCGTAAGACTAAAACGGAAAACAAAAGTGACCAAAGCGAAGAAGATGATTGTAGAGATTTTTATTCTGATGAGGAATTTAAGCCTAGGTTAATTGAAAATGCTGCTGTTCATAGCTGCCCTCAATGTGGTCAATCCTTTAAAACTGCCGGCCTTTTACGCAGCCACCTCAATCGTACGCACGATGATAAATCCTCGGAGAACTCTCTTAAAAAGGAAGGCAAGCAAATACCGTGTAATGAATGTGATCAAATATTTCCCAGTAAAAAATCTCTCTACGGACATATAGTAGACTATCACATGGGATTTAAGTGTAACATGTGTGACAAACGTTTCAAACAGTTGCAACAACGTGATCGTCATGAATTTTGCCATACCGCAGCTCGTGTCTTCTCTTGCCATATCGAGGGTTGCGACAAAAGCTTTACCCACAAGTATTATTTACAGCGCCACCTGGACAGTCATAATAAAGAGCGTAAATTTGTATGTGATTTTGAGAATTGCAGTAAAGCTTTTCACACTTTGCGTTGTTTGAAAGCGCACAAAAATCGTCATACTAAACCGAAAAATCTAATATGTGATACTTGTGGCTATACCTGTCGCGAATACGATCGTTTGCGTATACATCAACGGGTACATACGGGAGAAAAACCTTATGGTTGTCAAGAGTGCGGTAAAAGATTTACTAGTAATGCAGCACTTTTGGAACACACAGCCTCACATACCGGTATACGTTCGCATGTATGTAGTCAGTGTAATGCAACATTTACACGCCAGAAATCGCTACATCAACATCGACTGAAATGTACTGCTAGTACGGTGACTGCAACactaactaactaa
Protein Sequence
MYHIQNLHFEYIRKEECNEFYKNDEFKEEKYDEVSESLNSCDVLYDCKVNDDAVNSSEEETIKVLEVRPKFSKITSSTKETNIEEENHLEETSKLSTVYEIGDPFAPNQKFEALLCPDCQELFFLKKEYDEHVVKEHNGHKCPKCDMRFRHRHHLRRHLQNMHEDCEERKQNKRLKQRIPCPYAECPKSFTLKESLNYHLEFHTMKCTFVCNFENCSKSFPTQQRLDQHQEKHTMARTFVCDFDNCNKAFANKTRLKAHQDVHALAKRYICDACGYSCRASTTLRIHKRMHTGERPYTCKICENAFTSQATLHLHMNTHATIRPYVCQICQATFANRQILERHAYTHAEEKLFKCLLCDKAFKQPHGLDGHMRRLHLEPRPKKIVTPYLTNSEPTTKCGEIFCDHLKNVTISCSFCQIKLFTYQDFLLHIENEHFENITIESNEFSENEELNVESSDDQFETLECCEILYDYKENDEENDNSSQEEEEENLNVTNIETIISKTIDEEQNHSKESSQLSNIRESDDDVASSKQKEIETCPDCQEIFLLKKEYNQHVVEQHNGHKCPKCIMRFRHRHHLKRHLQNTHDKGKTNVRFPQRVNCPHPDCPKSFRFQDALNYHLEFHTMKCTFVCDFENCTKVFPSQQRLEQHQEKHTTARTFVCDYENCNKAYLNKRNLDEHRETHATAKRYICDNCGYSCSNTTTLKIHKRIHTGERPFPCKICEKSFISQARLYLHMNTHADIRPHVCQICQATFANRGTMKRHSLIHSEEKLFKCPLCDKAFKQPNGLHGHMRESNEFEDNEEFNSNEIEDNDNLNSNEIEDNEDYNSNEIEENEDYNSNEIEENEDYNSNEDNAEVEVENSDVLETLECCEILYDLEDNGGEEHSFEDESMDVETVIIDTIEKVEDHTEEPSLHSPKNEIDEPDSPKQKNAESSICPDCKELFLLKKDYDQHVVEQHGGHKCSKCDMRFRHRHHLKRHIQNIHDKGKTHIKFKQRVNCPYPDCPKSFSFQESLNYHLEFHTMKCTFVCDFENCTKAFPSQQRLEQHQEKHNMTRKFVCDFENCGKAYLSNQSLKAHKEIHAPAKRYICDNCGYSCSTSTALKIHKRTHTGERPFTCKICEKSFTSQATLHYHTNTHVTIRPHVCEICQATFTNRHTMKRHLLIHSEKKLFKCQLCDKAFKQPQCLDGHMRGVHWEPKPKKVKNFKNISNSSETTTTFYLPATTTKCGEIFCQNFNDFFICCAFCQMKSFQFEEFLQHLKNVHINDYRQQIAKVANEYLNIEVKNESLLCEKKGDCKEWQLETQSMTDDSENVHDDGNDSNDSSEEEKFRILKKTKRRVLRKRNSKQSQSTSSEELDIPENNCNSPLNDSFSKQADSSKKKKHKDLEYSCSECTEIFAQKKHLDHHVIQLHNGYKCPQCDKRFGRSYHVTYHLKTHTIEKKFICLMENCGRGFIDEDYLKRHLEVHTMERTFICEFENCGKAFQTHRRLASHQYRHRIPKKFVCDMCGHGCRSNTELITHQRVHTGEKPFVCKVCSKPFISKTALTEHMITHSETRPHVCGICQAAFANRRVLVRHSFIHSEEKTFKCKLCESAFKHPNSLQGHMRNVHGQAKHKKGREKNNNRLNKVYNDKSLLANMLKLMRTFNFNSQPKTKCGEIFCHNTNDFTVYCTFCEMKSFSFEDFLRHLKTLHFASEMCKNESTTYCNTKLEAEEDKIYDTLIKSYNDEDQTDFENTAALDDRGFDVDDDADYCDNDSYDEPLVVLKKKLVKQRSKRRKTKTENKSDQSEEDDCRDFYSDEEFKPRLIENAAVHSCPQCGQSFKTAGLLRSHLNRTHDDKSSENSLKKEGKQIPCNECDQIFPSKKSLYGHIVDYHMGFKCNMCDKRFKQLQQRDRHEFCHTAARVFSCHIEGCDKSFTHKYYLQRHLDSHNKERKFVCDFENCSKAFHTLRCLKAHKNRHTKPKNLICDTCGYTCREYDRLRIHQRVHTGEKPYGCQECGKRFTSNAALLEHTASHTGIRSHVCSQCNATFTRQKSLHQHRLKCTASTVTATLTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-