Lcup003560.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lucilia cuprina
Gene Symbol
zfh1
Assembly
GCA_001187945.1
Location
JRES01000955.1:247301-259615[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 37 8.1 5.4e+02 1.1 0.1 10 23 11 24 10 24 0.94
2 37 0.092 6.1 7.2 1.7 3 23 31 52 30 52 0.88
3 37 8e-07 5.3e-05 23.1 0.3 1 23 58 80 58 80 0.98
4 37 0.0004 0.027 14.6 0.4 1 23 521 544 521 544 0.97
5 37 0.0044 0.29 11.3 1.1 1 22 550 571 550 573 0.90
6 37 4.9e-08 3.2e-06 26.9 2.5 1 23 576 598 576 598 0.98
7 37 9.1e-06 0.00061 19.8 0.4 1 23 604 628 604 628 0.95
8 37 0.0011 0.07 13.3 3.9 1 23 633 655 633 655 0.97
9 37 0.00028 0.019 15.1 0.3 3 23 663 683 661 683 0.98
10 37 0.0006 0.04 14.1 4.8 1 23 689 711 689 711 0.94
11 37 5.5e-06 0.00037 20.5 0.0 1 23 717 739 717 739 0.98
12 37 1.1e-05 0.00076 19.5 0.8 3 23 785 805 783 805 0.98
13 37 0.0079 0.52 10.6 8.1 1 23 811 833 811 833 0.95
14 37 0.00013 0.0086 16.2 1.5 1 23 997 1019 997 1019 0.98
15 37 0.008 0.53 10.5 3.1 1 23 1024 1046 1024 1046 0.97
16 37 2.2e-05 0.0015 18.6 0.9 1 23 1049 1071 1049 1071 0.97
17 37 5.5e-05 0.0036 17.3 0.9 1 23 1077 1102 1077 1102 0.97
18 37 0.013 0.84 9.9 0.1 1 23 1108 1130 1108 1130 0.98
19 37 1 68 3.9 0.2 1 19 1136 1154 1136 1156 0.91
20 37 0.0022 0.15 12.3 4.9 1 23 1164 1186 1164 1186 0.95
21 37 9.5e-05 0.0063 16.6 0.2 1 23 1192 1214 1192 1214 0.98
22 37 8e-06 0.00053 20.0 2.8 1 23 1382 1404 1382 1404 0.98
23 37 0.00013 0.0087 16.2 2.2 1 23 1409 1431 1409 1431 0.98
24 37 0.0014 0.093 12.9 1.6 1 23 1434 1456 1434 1456 0.97
25 37 0.00061 0.041 14.0 1.1 1 23 1462 1486 1462 1486 0.96
26 37 0.0009 0.06 13.5 0.2 2 23 1493 1514 1492 1514 0.97
27 37 0.00069 0.046 13.9 1.5 1 20 1520 1539 1520 1542 0.94
28 37 0.00091 0.061 13.5 3.9 1 23 1548 1570 1548 1570 0.95
29 37 3.2e-05 0.0021 18.1 0.2 1 23 1576 1598 1576 1598 0.98
30 37 0.00021 0.014 15.5 2.7 1 23 1699 1722 1699 1722 0.97
31 37 2e-05 0.0013 18.7 3.1 1 23 1727 1749 1727 1749 0.99
32 37 0.00048 0.032 14.4 0.9 1 23 1752 1774 1752 1774 0.96
33 37 0.028 1.8 8.8 2.1 1 21 1780 1802 1780 1804 0.92
34 37 0.0064 0.43 10.8 0.2 1 23 1810 1832 1810 1832 0.98
35 37 0.00015 0.0098 16.0 1.5 1 23 1838 1860 1838 1860 0.97
36 37 0.00016 0.011 15.9 2.4 1 23 1866 1888 1866 1888 0.95
37 37 2.4e-05 0.0016 18.5 0.2 1 23 1894 1916 1894 1916 0.99

Sequence Information

Coding Sequence
ATGTCAGAAAGGACAACATATGCAGATATTTTTGCCTCATCCTATCAATTGGCGATACATCGTGAAATGCACACAACAGAGCGtaaatattgttgtattatttgtGCCGAAAGTTTTAACGATTCAAAGGCTTTGTATCATCATCAGGCATTACATGCgaaggaaaataaatatgtttgtaatttatGTGGGAAATCTTATAGGCAATCGGCTGGTTTGTCACAACACATGAGATGGCATAGAAAGCAGCAGGAGCGTTctttaataattgatattgaaaaatatttacgcATTTTAAATATGGAAAAACGTAAATCTGTTAatgaaagattaaaaaatgtaaaattacagAGTAATGTTAATAAAACTGCGCCTGGGGTAAAAGCCAAGGCAAACGAAGAAACTAATTTAGAAGAGTATCCCAAATTAAGAAAACCCAAACCGGCTACTTTACTAAAAATACAAGCGAGACAGAAAAAAACTAACGATTTAGCTATAAAGGCGACAGTAAAAGATTTGGAAACTGCAGACGAAAAACATGTGCAAGTGCCTTTGCGCCAGGAATTTCTCGATAAGAAACAACAACTGGAAAAGGCTACTacgaatttattgaaaaaatatgaaatacgtAAGATGCAAGGTCGTCTTCTAGATGATGATATGTGTAGTTTAGATTCCGAAGAGGCACAGCCTTTAACACTACACCAGGAACTCGATTTACAATTTAATGATCTAAAATTAAAGGATAATGAGAACCAAATAACTAAtgtcaaaaacaacaaagaattaAACTTTCTCGAACAACATTTggttaacattttatatacaaaagtacAAGCTCATCCAAATGGTTTCTTTGCGGAAAATCTTCCTTTATGGTATAAGAAAACCTTCGATAAGGATATAGCTAAAGATTGGCTAGAACTGATGGAAAGATCacgtaaattttatatagaaaaagtacaaaacaagACTGTGCTATATAGCAAGGAAGTGGAATTTACGGATATAAAAGCTTCTGGAGACATGGCGGAAGCACCCGAGACAGAAAAGGAGTCTACGcatttaattgaaaaattattcgaaaagatgttaaaaaattgttttttacccgtaaattataataaaccacAAACGCAAACCTGTGGAGAGATAATTTGTGAAAATCTAcaagaatttataattaattgtaaattgtgtaaaatcaaaatatttgagTTTGAAGAATTTGTGCAGCATTTTAAGAATGTCCACTTGGATAAGGCGTTAATAAATGATAGCACAACAGAAcggaaaatagaaaataaattacatgaAGATCAGGAGGAAAATTATGAGCGTGTGATTAAGTTAGAAATATCTGAGGCACATGAACCATTGAAAAATGATGAAAAGTTTACAGCAAACATCGATAATGAAGAATTCTTATGGGAGGCGGACAATAGTAACTATACGGATGATGACAAGGATGAGGATTATAATACAGAAGATGACGGAGACCCGGAGGAGGATGAGGAACAAAGCAAAAGTATAATGAGAAAGCCGCGTAAACCTAAAGAATTTTCCTgtgaaatttgcaataaaaagtaTGCCGACTCTAGACGCTTACAGCTGCATGTGAAAATTGTACATTTACGCGAAAAACCTTACAAATGCTCTATGTGTGATCAGGCTTTTGCCGAAGAACGTACGCTTAAGAATCATGTGGGTCATAAACATACGGGTTATGAGTGCCCCGAATGCCACAAGAATTTCTCAACAAATCGCAATTTGAAACGACACATGCTAATACATGTAGATAAAAAAGAATTCATTTGCCAAGAGGATAATTGTGGTAAGGCGTTTGCCACCAAGGGTCAGCTAAAAGATCATCAACGCTATCATACTAGTGAAATGTTTATTTGCGAGGAATGTGGCTATAAGTGCCGGCAACGCGAATCACTAATTGTTCATAAACGCCATCATACGGGAGAGAAGCCATTTGGATGTAAGCTTTGTGATCGTCGTTTTGGTTCGAAACCTTTACTCAATGAACACATGGCCACGCATGAAACGGAACGTAAACATATTTGTGATGTTTGTGGTAAAAGTTTTAATCGGCCCAAGGCTTTATATCAtcataaacatttacatttagGCGTTAAGAAGTTTGTTTGTAAAATCTGTGGTCAGGCCTATGCTCAAGCGGCCGGTCTATCGGCTCACATGCGAAAGCATAGAGAAGAGGGTGGCTCTGCCTCTTTTACCACCGAACCTGCGCTACCAcctaataatacaaatattttaaatTGTAAAAGACATGAATCCTTAAGGGAACATAAACGTCAGCATACGGGAGAGATACCGTTTGGCTGTGAAGTATGTGGAcgtagttttagtttaaaaaaattactgacCAGACATATGAGTAGTCATGAAACGGTGCGTAAACATGTTTGTAATGTTTGCGGGAAAAGTTTTAATCGACACAATGCTCTCTATCATCACAAACATTTGCATTCGGATGTTAagaagttttttgtaaaatatgtggTCAGGCCTATGCTCAGACAGCGGGACTATCCGCTCATATGCGAAAACATAGAGAAAATCataatatgtaatttttgtcaaataaaaatatttgaatttaatgaaTTCGTGGAACATTTTCGCACTATACACTGGCCAGAAATTAATGGAACacataataaatacaatacTCTTTTACACAATGTACATCCAGTTAAGCAAGCTAAAATTGAAGATGTTAAACAACTAAAACTAGAGGTAAATGAACAGGCAAAAGATTTTCATATTGAGGACGAGTCGATGCAAGGTAGTGAAAATGACTGGAGGCCGGAGTTGGAAATGCAGCAAAATATAAGTAATAGTGGGTTTTCTAATCAAGAGGAAGACAATTGCAGTGATAGAGAAGAATCCATAGGAATATTAAAGAAGGAATATTTGCAGAATGAAAAACCCAacctgaaaagaaaaaaacatgactTTAAATGTTCTATATGTGCACGTACCTTTATTAAAAAGTCAACATATGAAACACATATAAAAGAGCATAAGATTATGCCATACAAATGCACTAAATGCTCGCGATCCTTTGACGAAGAGTTGCAACTTATGCAGCATCAACATTTACATGATGGTTATGCTTGTGATATTTGTCAGAAAGTTTTTAAGAAGAGGAATAACTTAGTTTCACATAAAGAAACTcatgtgaaaacaaaaaatttcaaatgtacTTATGAAAATTGTGAGAAAGCATACTCTGGTCAAAGGCAACTGCAACGTCATATGCGTTTAGTACACATACGAGGTGCATGTTTTGTTTGTGATATATGTGGCTCTAGGCAGCGAGATAAAATAGCTTTGGCCGATCATATGCGTTCGCATACTGGTGAAAGACCCTTTGCTTGCAGTTTATGTGCGCGACGCTTTATGACGAAATCGAGACTGGGCGAACATAAAGCCTGTCATGAAACGGAACGTAAACATGTGTGCGAGGTTtgtggtaaaaattttaatcgtgCCAAGGCTTTGTATCATCATAAACACTTGCATTTGGATGTAAAGAAATTTGTGTGTAAACTTTGCGGTGCTGCTTATGCCCAGTGTGCTGGATTATCGGCTCATATGCGTAAACATAAAGATCAACAAGTATTCAAACAGctgtttaaacttaaacttggaaaaatgttaaaaaattgttttttacctatacaatataataatttaactaGCAAAACTTGTGGCGAAATTATTTGTCAAAGTGAAACTGTCTTCAGCATAGTGTGTAAATTTTGTGACTTAAGAATTTTCGAATATGAAGAATTTCTACAACATTTTCGCAATAACCACTGGACAGAGCAGTTAAATGTAAAGAATGATGGAGGCAATAAAGAATGTAATGAAAAATCTTTAGATCCAAAcgaaatagaaaatgaaaaactcgTAAAGAGAGATGTATGTTTggaatcgaaaattttatatgatgTAGAAGAAACTGAAGAGGATTTGGAGACAAATGATGACGATGAATGGCAGCCGGAAATGGAAGAGGAACAAAATGAGGATTCTAATGATATGACGGAAACAAAGGCAATATTAAAAAAGCCTGTGAAggacaacaaaaaaagagaacgTCCCTTTAAATGTGAGATGTGTACGCGAACATTTAGCAACAAGTCCAACTATGAAGCACATAAACTTAAGCATAAAACTGTACAATACAATTGCGAGAAATGCAGTAAAACTTTTGTAACAGAACATGAACTTGGCCTTCATCAGCGTTCTCATAATGGTTACAGTTGTTCAATTTGTAATATGTCTTTTATGAAATACGAATCATTGCGTACACACAAAGAGTCTCATATAGAaaccaaaaatttcatttgcacTTATAAAGATTGCAATAAAGCGTTTGCCACCAAACGTCGTCTAGGCTCCCACATGCGCTTACACATACGAGAACCTACACTGGTGTGTGAATTGTGTGGCGGACGTTATCGCTCGACAAAAGAACTAAACGATCATATACGCAGACATACGGGTGAAAAGCCATTTGCTTGCAATTTATGTGATCGACGTTTCACATCGAAATCTTTATTGGGCGAACATATGGCGTGTCATGAAACGGAACGTAAACATGTATGTGAAGTATGTGGTAAGGGCTTCAATCGTCCCAAGGCATTATACCAtcataaacatttacatttggaagtaaaaaaatttgtgtGTAAAATATGTGGTGCTGCATATGCTCAGTGTGCAGGATTATCGGCTCATATGCGTAAACATAAGGAAAAGGCAAATATGCCAACAGATTTCCCTAGAAATGATATTATTTTGTATgaatggaaaaataatattaaaagtgaaaatgaaACAGATGAAGAATTTCTAAGTAATGACTGCGATAAGAGGTATCTAGCAAATGAGCTCGTTGTTAAACAAACGTCTGAAGGCGGCCAAGACATTGATAGtgaaaaagaagaagagaaTGGGAATTCAAGTGAGAGTTCAGaggatttttcaaaatctttggTAATTTTGAAAAAGGCCACAGACAAATCTTCCAAGACCcgtaaaaagaaacttttcgaATGTACACAATGCAAACGCaagtttaatacaaatttctatTTACGTATTCACGTACGACAAGAGCATGAACCAGTAAGCTTTCAATGTGATAAATGCAGCAAATCCTTTGTGGAAAaacgttatttaaaattacaccAGCGTTCCCATATAGGTTACACTTGCCAGATTTGCAATAAAGTCTTTGATAAATATGAAGCCCTACGCTATCATAGTGAAAGCCATATAGAATCGAGAAATTTCATTTGTGACTATGAAAAGTGTGGTAAGGCATTTCCCAACAATCGTCGACTAAGTGCTCATAAACGTTGCCATTTTGCTGTGGCACCGTTTGTTTGTGAGATTTGTGGTTCACGCCAGCGTAGTAAAGAGTTTTTAATCGTTCATATACGCACGCATACAGGGGAAAAGCCCTATGCTTGCAGTCAATGCGATCGTCGTTTTGCCTCCAAACATTTTCTACAAGATCATCAAGCTGTACATGCTACCGAACGTACTCATGTGTGTACGGTTTGTGGTAAGGCTTTTGCCAGCAGTAAATCTCTCTATCATCATCGTGATCTGCATTTGGGCATAAAGAAATATGTGTGTAAAATATGCAATAGTGCATACACACAGTCGGCTGGACTGTCGGCCCATATGCGTAAACATAAACAGGATAGCGGTCTATTAGATGTTGAGCAAACAACATCTAACAATTGA
Protein Sequence
MSERTTYADIFASSYQLAIHREMHTTERKYCCIICAESFNDSKALYHHQALHAKENKYVCNLCGKSYRQSAGLSQHMRWHRKQQERSLIIDIEKYLRILNMEKRKSVNERLKNVKLQSNVNKTAPGVKAKANEETNLEEYPKLRKPKPATLLKIQARQKKTNDLAIKATVKDLETADEKHVQVPLRQEFLDKKQQLEKATTNLLKKYEIRKMQGRLLDDDMCSLDSEEAQPLTLHQELDLQFNDLKLKDNENQITNVKNNKELNFLEQHLVNILYTKVQAHPNGFFAENLPLWYKKTFDKDIAKDWLELMERSRKFYIEKVQNKTVLYSKEVEFTDIKASGDMAEAPETEKESTHLIEKLFEKMLKNCFLPVNYNKPQTQTCGEIICENLQEFIINCKLCKIKIFEFEEFVQHFKNVHLDKALINDSTTERKIENKLHEDQEENYERVIKLEISEAHEPLKNDEKFTANIDNEEFLWEADNSNYTDDDKDEDYNTEDDGDPEEDEEQSKSIMRKPRKPKEFSCEICNKKYADSRRLQLHVKIVHLREKPYKCSMCDQAFAEERTLKNHVGHKHTGYECPECHKNFSTNRNLKRHMLIHVDKKEFICQEDNCGKAFATKGQLKDHQRYHTSEMFICEECGYKCRQRESLIVHKRHHTGEKPFGCKLCDRRFGSKPLLNEHMATHETERKHICDVCGKSFNRPKALYHHKHLHLGVKKFVCKICGQAYAQAAGLSAHMRKHREEGGSASFTTEPALPPNNTNILNCKRHESLREHKRQHTGEIPFGCEVCGRSFSLKKLLTRHMSSHETVRKHVCNVCGKSFNRHNALYHHKHLHSDVKKFFVKYVVRPMLRQRDYPLICENIEKIIICNFCQIKIFEFNEFVEHFRTIHWPEINGTHNKYNTLLHNVHPVKQAKIEDVKQLKLEVNEQAKDFHIEDESMQGSENDWRPELEMQQNISNSGFSNQEEDNCSDREESIGILKKEYLQNEKPNLKRKKHDFKCSICARTFIKKSTYETHIKEHKIMPYKCTKCSRSFDEELQLMQHQHLHDGYACDICQKVFKKRNNLVSHKETHVKTKNFKCTYENCEKAYSGQRQLQRHMRLVHIRGACFVCDICGSRQRDKIALADHMRSHTGERPFACSLCARRFMTKSRLGEHKACHETERKHVCEVCGKNFNRAKALYHHKHLHLDVKKFVCKLCGAAYAQCAGLSAHMRKHKDQQVFKQLFKLKLGKMLKNCFLPIQYNNLTSKTCGEIICQSETVFSIVCKFCDLRIFEYEEFLQHFRNNHWTEQLNVKNDGGNKECNEKSLDPNEIENEKLVKRDVCLESKILYDVEETEEDLETNDDDEWQPEMEEEQNEDSNDMTETKAILKKPVKDNKKRERPFKCEMCTRTFSNKSNYEAHKLKHKTVQYNCEKCSKTFVTEHELGLHQRSHNGYSCSICNMSFMKYESLRTHKESHIETKNFICTYKDCNKAFATKRRLGSHMRLHIREPTLVCELCGGRYRSTKELNDHIRRHTGEKPFACNLCDRRFTSKSLLGEHMACHETERKHVCEVCGKGFNRPKALYHHKHLHLEVKKFVCKICGAAYAQCAGLSAHMRKHKEKANMPTDFPRNDIILYEWKNNIKSENETDEEFLSNDCDKRYLANELVVKQTSEGGQDIDSEKEEENGNSSESSEDFSKSLVILKKATDKSSKTRKKKLFECTQCKRKFNTNFYLRIHVRQEHEPVSFQCDKCSKSFVEKRYLKLHQRSHIGYTCQICNKVFDKYEALRYHSESHIESRNFICDYEKCGKAFPNNRRLSAHKRCHFAVAPFVCEICGSRQRSKEFLIVHIRTHTGEKPYACSQCDRRFASKHFLQDHQAVHATERTHVCTVCGKAFASSKSLYHHRDLHLGIKKYVCKICNSAYTQSAGLSAHMRKHKQDSGLLDVEQTTSNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-