Llun015878.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lordithon lunulatus
Gene Symbol
ZEB2
Assembly
GCA_963942505.1
Location
OZ012669.1:4215668-4228054[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.86 1.4e+02 4.7 3.0 3 23 595 615 594 615 0.97
2 10 0.012 1.9 10.5 3.4 2 23 654 675 653 675 0.97
3 10 0.00023 0.037 15.9 0.3 3 23 683 703 681 703 0.95
4 10 0.00039 0.061 15.2 0.2 1 23 709 731 709 731 0.97
5 10 0.052 8.3 8.5 1.7 1 23 734 757 734 757 0.92
6 10 0.00027 0.043 15.7 2.2 1 20 761 780 761 783 0.94
7 10 0.0001 0.016 17.0 1.1 1 23 789 812 789 812 0.98
8 10 0.015 2.4 10.2 9.3 2 23 817 838 816 838 0.97
9 10 7.8e-05 0.012 17.4 1.3 1 23 844 866 844 866 0.98
10 10 0.0025 0.4 12.7 0.4 1 21 872 892 872 893 0.96

Sequence Information

Coding Sequence
ATGGGACGTTTTAGACGTTGTGCAATGCAGGGCTGTGAGGACACAGTCTCAATAAGGCATCGTTTCCCCAATCCAAAAAAGAGGGAGGATTTAATGAAAGTATGGATTCGTCTTTGTGCTGACAATAAATTATTCGAAGTAACAGCAAAAAAGATTTATGACTTACATAGAGTATGTCATATACATTTTGCATCAGATACACAACATACAAATAATACTTTGATAAAGGATGCAGTTCCAACATTGTTTTTACCAGTACCTAAGGAGGAAATGCTAGTGTTGGAAAAGCTTTCCAAAAATATGGTGAAACATACAAGATGTGCAGTGTTTGGCTGTGAAGACAATACGTCTTCACAACATAGATTCCCAAACTATAAACACAAAGAAGACCTTTGTGCTAATTGGGTGACTCTgtgcaaaaacaaaaatttattggGATTAACACCTGAGACAAATTATAAGCAGCACAGGGCTTGGTGGCCCATCTTTGAAAAGCTGTTCCCCGATAAACCGCGCCCAATGTATTCTATGATTTGTGAGGATCATTTCAATGTGAACCAGTTTAGAAATCGAGAAAAGATCTTTTTAAAACCAAATGTCTTTCCTGATATGCTTGCACCATATGATGGAGTGCGGAGGAAGATAAAAAGTACATCAGAACAGATTCGGGTGGCTGCTGATGGAGCTTTGGAGATTATTGATAGTAGTGATGATGACTTGGACACAgaACCTCCAGATGAGACAAAGATATCACAAACAAATCCAACTGAACTAAAACCATTCCAAATAACAAACACTACTGCTGCCACGGCACCAATTGACCATCAGTATGCTCGTTCTCAAATTATTGACTTCACTGCAAGTGCACCTATTGAAAATTCATTTGAGCCACCATCACCGATCGATAATGTTGATGATGATATTGAGGAAGTGCCTATATTCCATGTATGCAGACTCTGTTTGACAAATGAGCATGTCACCGACATCTCAATGGAAGGTTTTAAGACATATGATTATGACAACATTGAGGAGCCAAATAATGTAGTTGATATATTGAAGAAGTACACACATATTGAGTTCTCAGATCCCACCCTGAAATCAATGAGTGTGTGCAAGTCGTGCCATAAAATGCTGCAGAGCATACAACTTTTCGCCAACATGTGCCGTAAGGCCGAACAGTGTCTGACCACAATTGACCAACATAAAGTGTCCATCGAAATGAATCCACTAACTGAAGCACCAGACCTTCAGGAAAAATCAGACGCGTTGTACAATAATCTGGAGACGAAATTCACTAACATACTAAGCATACAAATGTCACTGAATTCGGTTGTAGAGGAGAATGAGTTGACGAATGTACCAAATGAACCTACGATAGAAACCGCGCTATTAAAAGATGAAATTGTAGGCCCTACAAAAGTAGAACCGATCAAACCAATAATAGTTGTAAATAAACCAACACCATCAGTTGTAGATAAACCCACACAACTAGCACCAATTGATGATAAATCACTCTGCGAATTATGCGGATGTAAATTAGCCAAAACAGTCTTGCATGGCCATCAATTGGGTTGCCGCGCCAACAAAGAGACTGTAGTCGAAACTATGACCCGTATGCACCACTGCATTTATTGCGACAATATTTTCCATACTGAGCGTGCAAGGGAGATGCACGCGAAGGTATATCACTGGAGTTCCAAACTGCTTTGTGAGATATGTGGTGATGAGGTGACTGGCTGGAAACTGGCCACCCATATGCAGGCGCATTCTCGGGTGTGGCTTTGCTATATATGCGGCGAGCAGTTTCCAAATCGGGTATACCACCACAAACATGTCAAACGGCATGAGCGGCTTCAAAGTGGCATCAAGAAGGTGAAAAACTGTAAGGTGTGCAAAATGCCTGTGATAGATTTGAATGAACATAGAATTAAGTATCATCCGAAAGTGAAAAAATGGCTTAAGTGTactatatgtaatattatttgttcTAATATGACGTCGTATGAGAAACACAAGAAGACGCACGAGGAGATTACCGTGCATTTGTGTAACATATGCGGGCAAGGGTTCGAGCGCGAGGCCCTTTTGAATAATCATGCTCTAACGCATGGGATTGCTAAAAAGTATAGTTGTCATATATGTAAAGAGGATTATGACGATTGGGGCGAGTTGCAGGAGCACAAAGAGGTGCATAAAGTTCACACGTGTACAAGATGTGATCAGAAGTTTATGACGGATACGAAGCTGCGCATTCATGTTGAGTTGGAGCATTTGCAGAATTTCAAATGCGAGACTTGCGGCAAGTGTTTCCGATTGAAACGATTGTTAAAGGAACATGTGCCGATACACTCCGGCATTTATCCGTTTAAGTGTCATATATGCGACAAGGGATTCTCGTTCGTGCAGTCAGTCAACGCGCATATACAGAAAGTGCATAACTCTGGACTTCAGTGTAAgCATTGCAACAAAGTATGCACCTCCAAAACGATGTATTACCACCACCAGATGAGTCACGCCGGTCTCAAGCCGTTCGTATGCCAGATGTGCACCAAAGGCTTCCAGTCACAGCGAACGCTGCAAGAGCACCAGCTCACGCATAGTGGACAGACCGCGTACAAATGCCCGAAATGCGGGTTGGCCATTGTACACCGGAGGACTTTAACGTTGCACTTGAAAAAGTGTAACTCTGAAATAACGAGAAAAGTTGGTCAGCGTCGTCGtaaatga
Protein Sequence
MGRFRRCAMQGCEDTVSIRHRFPNPKKREDLMKVWIRLCADNKLFEVTAKKIYDLHRVCHIHFASDTQHTNNTLIKDAVPTLFLPVPKEEMLVLEKLSKNMVKHTRCAVFGCEDNTSSQHRFPNYKHKEDLCANWVTLCKNKNLLGLTPETNYKQHRAWWPIFEKLFPDKPRPMYSMICEDHFNVNQFRNREKIFLKPNVFPDMLAPYDGVRRKIKSTSEQIRVAADGALEIIDSSDDDLDTEPPDETKISQTNPTELKPFQITNTTAATAPIDHQYARSQIIDFTASAPIENSFEPPSPIDNVDDDIEEVPIFHVCRLCLTNEHVTDISMEGFKTYDYDNIEEPNNVVDILKKYTHIEFSDPTLKSMSVCKSCHKMLQSIQLFANMCRKAEQCLTTIDQHKVSIEMNPLTEAPDLQEKSDALYNNLETKFTNILSIQMSLNSVVEENELTNVPNEPTIETALLKDEIVGPTKVEPIKPIIVVNKPTPSVVDKPTQLAPIDDKSLCELCGCKLAKTVLHGHQLGCRANKETVVETMTRMHHCIYCDNIFHTERAREMHAKVYHWSSKLLCEICGDEVTGWKLATHMQAHSRVWLCYICGEQFPNRVYHHKHVKRHERLQSGIKKVKNCKVCKMPVIDLNEHRIKYHPKVKKWLKCTICNIICSNMTSYEKHKKTHEEITVHLCNICGQGFEREALLNNHALTHGIAKKYSCHICKEDYDDWGELQEHKEVHKVHTCTRCDQKFMTDTKLRIHVELEHLQNFKCETCGKCFRLKRLLKEHVPIHSGIYPFKCHICDKGFSFVQSVNAHIQKVHNSGLQCKHCNKVCTSKTMYYHHQMSHAGLKPFVCQMCTKGFQSQRTLQEHQLTHSGQTAYKCPKCGLAIVHRRTLTLHLKKCNSEITRKVGQRRRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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