Basic Information

Insect: Lordithon lunulatus
Gene Symbol: zfh1
Assembly: GCA_963942505.1
Location: OZ012672.1:42966954-42982674[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.013 2.1 10.4 1.1 2 23 54 76 53 76 0.93

2 9 0.00019 0.03 16.2 0.9 3 23 104 124 102 124 0.95

3 9 8.6e-06 0.0014 20.4 0.6 2 23 131 152 130 152 0.97

4 9 1.6e-06 0.00026 22.7 5.9 1 23 161 183 161 183 0.99

5 9 6.8e-05 0.011 17.6 1.0 1 21 189 209 189 210 0.95

6 9 0.5 79 5.4 0.3 3 19 426 442 424 442 0.94

7 9 6.3e-06 0.00099 20.8 1.4 1 23 796 818 796 818 0.95

8 9 0.00016 0.026 16.4 9.4 1 23 824 846 824 846 0.98

9 9 0.05 7.9 8.6 7.0 1 21 852 872 852 873 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.013	2.1	10.4	1.1	2	23	54	76	53	76	0.93
2	9	0.00019	0.03	16.2	0.9	3	23	104	124	102	124	0.95
3	9	8.6e-06	0.0014	20.4	0.6	2	23	131	152	130	152	0.97
4	9	1.6e-06	0.00026	22.7	5.9	1	23	161	183	161	183	0.99
5	9	6.8e-05	0.011	17.6	1.0	1	21	189	209	189	210	0.95
6	9	0.5	79	5.4	0.3	3	19	426	442	424	442	0.94
7	9	6.3e-06	0.00099	20.8	1.4	1	23	796	818	796	818	0.95
8	9	0.00016	0.026	16.4	9.4	1	23	824	846	824	846	0.98
9	9	0.05	7.9	8.6	7.0	1	21	852	872	852	873	0.96

Sequence Information

Coding Sequence: ATGGTGGCGCGAAGTGAGAGCATGTTTGGGTGCTACGACAGCTACTCTTATAGACTTTGGAGTCTCGCCAATGTGTGGAACACCTGTCAATTTCCATCCCTAACGAATGGGGTGACCAAAGAGGGGGACGAGGCCAGTGCCGGCTCTGAATATTTCATCAAGTGTCCACAATGCCAGAAGGGTTGTCAGACGTTCCAAGCGCTTAAAGAGCACATGGAGGCGTCGCATCCCGACCTCTGCTCGGAGAACGGCACCATACCGACGCCAAACGCGGTCTCACCGACGCCCAGCCTGGGGGGTCCCTTCGGCTGCTCGCAGTGCACCACCTCGTTCTCCAGCAAGGACCAATTGGAGAAACACGAGCTGCTCCACTCGCCCAACGCTCAAGTGTCCTGtaaaatttgcaacaaaactTTTGCAAACGTTTACCGCCTCCAGAGGCATATGATCAGTCACGACGAGAGCGCGGTGCTGCGGAAATTCAAATGTACCGAATGCGACAAGGCCTTCAAGTTCAAACACCACTTAAAGgaACACATACGAATACACAGCGGCGAGAAACCGTTCGAGTGCGGAAATTGCGGCAAACGTTTCTCGCACTCGGGCTCATATTCTAGTCATATGACGTCGAAGAAGTGTCTGGTTATGAATTTGAAATTGGGCAGAACCCGGGCGCCGGGCTCCGCCGCCGCCCTTATGGAGAAGAGCGCGTCGCAGAACGCGCGCGGCCTGAAGCGCCCGCCGACGAATCCGCTCAACAACAACATCACCACCACCAATCACAACGCGTACCTTCCGATGCTTCCGAAATACCAAGAAGCCGCGGCTGCGGCCTTTTTACAAGCTACAAATCCTGCCATGCATCCATTCTACATGACACCACCCGGCATGTTAAATGCGAATGGCCATGCACTCAGCCCATACTCAATGCCTTCACTGGGCCACCTACTCGAGCAACTCCAAACCGCACAGAAGCCTCACGAAGAATTCACACCGGAGTCCATAAAACAAGAGCCTGAACTCAACAAATCGAGTTCGTCCAGTTGCGGTGATTTGGTGATGGACGAGGAATGTGAGAACAAGTCCGAAACTAACGAAAAAACTCCATCCGAAATAAACGCCAACACCCGAGATTTCGAGGCGGTGAAGAGAATCCTGGAGACAGTCAACGCGTCCGTGACCAAACAACTCCTCCAAGCGAACATGCAGAAGTTTTCCGACAACTCCAGCGATTGCCAAAGCATACGATCATCTCACTCACCTTTAGAACTCGCATGTCCTAGTTGTAAACGAATGTGCAGCAGCCAACTCGAGCTAGAAGAGCACGATTGCGACCAGAATGAAAAAAGTGAGGGCCTTGCGGCGAAATTGGAAGACGTAGCCGCTACAAAACATGACAACGAAATGAACGGCATGAGTGGAACGGAGGAAGAGCACGAGCACAACGATAAACACGATGAGTATGAAATGGACAACGAATCTGTTACAATGACCGACCAATTAACCGAGGATGGTAGAAAAGTAAGAGTGCGCTCGCTGATCTCCGACGAGcaattaaaagttttaaaagaCAACTACGCATTGAATCCACGACCAAAACGTGAGGAGCTTGCAAAAATCGCCGACCAAATTCGATTCCCCGTGCGCGTTGTCCAAGTCTGGTTCCAAAACACACGAGCCCGCGACCGACGAGAAGGCAGATTAATCCAAGTCCCCTACAACACGCCTCCGATGCTAAACCGATTTCCTCCAGCAGTGGTGCCTTCCAATCCGCAATATTTAGGCCACAAAGTCTACCCGCTAGCCCAATCCCCAGTCCACTATTCATCCGAACAACCCCTCGATCTCTCCACCAAAAAAGAGCACTCCCGCGAATCCTCACCAGCCAGCTCGCCTCGCCGACCTACATCCGCAAACCACCACTCGGACTCTGGCGACGAGGTCGTTAACTTAAGCCATAAATCATCCCGCAGCCCAACTCCGTTCCAACACCTACCCTACCAAAGTCATTACCAAGCCTCCAACTGCTCCTCGGAGCCGCGACGATCACCCTCACCGCTCGACTTCAACAACAGCAGCCGCCTAGCCCAAATACTCGCGCAACCCGCCCACAAACTCGCACTCTCCACCATGGGGCTGGTACCCATGGACCGACTGATGCAATTCGGCCCGCCCGATCTACCCAGTTTATCTCAATTGATCAACAACCGCATCTCCAGCATCAGCCCGAACTCCGATAAACGCTCGTGGACGGAAAACGGTGACCTGCACATGGATCACCACGAGGAAGATTTGAGTAGCAAACGCAGCAAGGTGTCGCAACTGGTTATGAAGAGTTTGGGCAGTCCAATGCTGGGCAATCAGGAGGTGGAGATTGAGGGGCAGTTCACGTGTGACCAATGTGATAAGGCGTTTTCCAAACAGAGTTCTTTGGCGAGGCATAAATATGAGCATTCAgGGCAGCGACCGCACAAATGTGACGAGTGTCCGAAGGCGTTCAAACACAAGCACCACCTCACCGAGCACAAACGGTTGCACAGCGGCGAAAAACCCTTCCAGTGCTGCAAATGCCTGAAAAGATTCTCGCATTCAGGATCCTACAGCCAGCACATGAATCACCGATACTCGTACTGTAAACCATACAGAGAGTAA
Protein Sequence: MVARSESMFGCYDSYSYRLWSLANVWNTCQFPSLTNGVTKEGDEASAGSEYFIKCPQCQKGCQTFQALKEHMEASHPDLCSENGTIPTPNAVSPTPSLGGPFGCSQCTTSFSSKDQLEKHELLHSPNAQVSCKICNKTFANVYRLQRHMISHDESAVLRKFKCTECDKAFKFKHHLKEHIRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRTRAPGSAAALMEKSASQNARGLKRPPTNPLNNNITTTNHNAYLPMLPKYQEAAAAAFLQATNPAMHPFYMTPPGMLNANGHALSPYSMPSLGHLLEQLQTAQKPHEEFTPESIKQEPELNKSSSSSCGDLVMDEECENKSETNEKTPSEINANTRDFEAVKRILETVNASVTKQLLQANMQKFSDNSSDCQSIRSSHSPLELACPSCKRMCSSQLELEEHDCDQNEKSEGLAAKLEDVAATKHDNEMNGMSGTEEEHEHNDKHDEYEMDNESVTMTDQLTEDGRKVRVRSLISDEQLKVLKDNYALNPRPKREELAKIADQIRFPVRVVQVWFQNTRARDRREGRLIQVPYNTPPMLNRFPPAVVPSNPQYLGHKVYPLAQSPVHYSSEQPLDLSTKKEHSRESSPASSPRRPTSANHHSDSGDEVVNLSHKSSRSPTPFQHLPYQSHYQASNCSSEPRRSPSPLDFNNSSRLAQILAQPAHKLALSTMGLVPMDRLMQFGPPDLPSLSQLINNRISSISPNSDKRSWTENGDLHMDHHEEDLSSKRSKVSQLVMKSLGSPMLGNQEVEIEGQFTCDQCDKAFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCCKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00429770;
90% Identity: iTF_00920563;
80% Identity: iTF_00920563;