Basic Information

Gene Symbol
-
Assembly
GCA_018904225.1
Location
JAEIFT010000044.1:38965-40413[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 1.2e-08 6.6e-07 29.5 3.2 1 23 118 140 118 140 0.98
2 13 2.7e-08 1.5e-06 28.3 2.5 1 23 146 168 146 168 0.99
3 13 3.3e-06 0.00019 21.7 1.0 1 23 174 196 174 196 0.99
4 13 1.1e-06 6.2e-05 23.3 3.0 3 23 204 224 202 224 0.98
5 13 0.00035 0.02 15.4 2.9 1 23 230 252 230 252 0.97
6 13 3.3e-05 0.0019 18.6 3.1 1 23 258 280 258 280 0.98
7 13 6.6e-06 0.00037 20.8 0.8 1 23 286 308 286 308 0.99
8 13 1e-06 5.9e-05 23.3 2.2 1 23 314 336 314 336 0.98
9 13 4.9e-07 2.8e-05 24.3 5.3 1 23 342 364 342 364 0.99
10 13 3.9e-05 0.0022 18.4 1.9 3 23 372 392 370 392 0.98
11 13 8.8e-05 0.005 17.3 2.8 3 23 400 420 398 420 0.98
12 13 5.6e-07 3.2e-05 24.2 2.2 1 23 426 448 426 448 0.99
13 13 2.8e-05 0.0016 18.8 7.6 1 23 454 476 454 476 0.99

Sequence Information

Coding Sequence
ATGGCCAGCAAAACAAAGTGGCTTATTGCGGACGAGCTATGCTGCGTTTGCATGTCCAGTTGTTCAGGATCTGGTACCGACACCAACGGCTGGCTGAATATATACACAGACTCTGATGCGGGACACTGCGTGAAGTTTTTAATAGAGGAGGTAACTGGCCAAGTGGTTAAACCAACTGAGGATCTACCTGAACAGATATGCCCCACATGCTTGACAGCAGCAAAAATTGCCTTCCATTTCAAGCGCCGCTTTGAGAATAGTATTGCGTGCTTCAACGGGAAACTCGAGGGGTTAGAATCTCTTACGGAAGATGGCAGTTACAATGGTGAAAGCGACAGCGTTGGATCGCCGTTCCCATGTCCACACTGCTCAAAGACTTTTACCCAAAAAGGCAATCTGAAGAATCACCTGCGCACTCATACTGGCGAGCGACCCTTCGAGTGTTCATACTGCACAAAGACTTTCACCCAAAAAATCAATCTACAGAATCACATACGCACCCATACTGGCGACCGTCCCTTCAAATGTTCCTACTGCTCGGAGGCATTTAAAGTAAAGGTCACTCTAAATATTCACCTACGCACTCATACGGGCGAGCGACCCTTCGGATGTTCACACTGCACGAAGGTTTTTACCCGTAAAGTCCAGCTGGAGAATCACCTACGCACTCATACTGGCGAACGACCCTACGCATGTTCACACTGCACGATGGCTTTTGTCCAAAAAGTTCAGCTAGATCAGCACCTTCGCCATCATACGGGCGACCAACCCTTTAAGTGTTCCGAGTGCTCAATGAGCTTTACCCGAAAATTTGTTTTAAATAGACACTTTCGTATACATACTGGCGAGCGACCCTTCAAATGTTCCCTCTGCTCGGAGGCTTTTAACGATGGGACTAATCTTAAGAATCACCTACGTACTCATACTGGTGAACAACCCTTTAAGTGTACAGAGTGCTCGAAAAGCTTTAGCCGACAATTTGATCTAGATAGACACTTGCTAAGCCATTCGGACGAACGACCCTTCAAGTGCTCTCATTGTTCCAAGTCCTTTACATTAAAAGGCAATTTAAAGAATCACCTACGTACTCATACTGGCGAGCGACCCTTTGGTTGTGAACACTGCACGATGGCTTTTTCCCAAAAAATCCAGCTAGATAGACACCTACGCACTCATACGGGCGAGCGACCCTTTGGATGTCCCCACTGCACGATGGCTTTTGTCCAAAAAGTTCAGCTGAATCAACACCTTTGCACCCATACTGGCGATCAACCCTTTAAGTGTTTGGAGTGTTTGAAGAGTTTTAGCCGAAAATTTGCTCTAGAAAGACACCTACGCACTCATACTAACGAGCGATCCTTTAAATGTTTACACTGCTCGAAAACTTTCTTTCAAAAAGTCCATCTTGAGAAACACCTTCGCTCTCATTCGGCCGAACAAAATAAATGA
Protein Sequence
MASKTKWLIADELCCVCMSSCSGSGTDTNGWLNIYTDSDAGHCVKFLIEEVTGQVVKPTEDLPEQICPTCLTAAKIAFHFKRRFENSIACFNGKLEGLESLTEDGSYNGESDSVGSPFPCPHCSKTFTQKGNLKNHLRTHTGERPFECSYCTKTFTQKINLQNHIRTHTGDRPFKCSYCSEAFKVKVTLNIHLRTHTGERPFGCSHCTKVFTRKVQLENHLRTHTGERPYACSHCTMAFVQKVQLDQHLRHHTGDQPFKCSECSMSFTRKFVLNRHFRIHTGERPFKCSLCSEAFNDGTNLKNHLRTHTGEQPFKCTECSKSFSRQFDLDRHLLSHSDERPFKCSHCSKSFTLKGNLKNHLRTHTGERPFGCEHCTMAFSQKIQLDRHLRTHTGERPFGCPHCTMAFVQKVQLNQHLCTHTGDQPFKCLECLKSFSRKFALERHLRTHTNERSFKCLHCSKTFFQKVHLEKHLRSHSAEQNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-