Basic Information

Insect: Lordiphosa clarofinis
Gene Symbol: zfh1
Assembly: GCA_018904275.1
Location: JAEIGQ010000171.1:229401-236352[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 9.7e-05 0.0049 17.3 1.2 1 23 137 159 137 159 0.97

2 15 0.0022 0.11 13.1 1.8 3 23 167 187 165 187 0.94

3 15 0.00013 0.0064 17.0 0.1 1 23 323 345 323 345 0.98

4 15 0.00087 0.044 14.3 0.8 1 23 351 373 351 373 0.98

5 15 0.00027 0.014 16.0 4.0 1 23 403 425 403 425 0.97

6 15 0.00019 0.0099 16.4 0.5 1 23 449 471 449 471 0.95

7 15 0.016 0.8 10.4 1.6 1 23 477 500 477 500 0.97

8 15 0.037 1.9 9.2 0.4 3 19 509 525 508 526 0.95

9 15 0.00022 0.011 16.2 5.6 1 23 535 557 535 557 0.97

10 15 0.065 3.3 8.5 0.4 2 23 563 584 562 584 0.96

11 15 1.3e-05 0.00065 20.1 1.0 1 23 593 615 593 615 0.98

12 15 0.0014 0.074 13.6 0.1 3 23 623 643 621 643 0.97

13 15 7.7e-05 0.0039 17.6 0.5 1 23 649 671 649 672 0.95

14 15 2.1 1.1e+02 3.7 0.3 1 23 682 704 682 704 0.95

15 15 0.0073 0.37 11.4 0.3 1 23 1194 1216 1194 1216 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	9.7e-05	0.0049	17.3	1.2	1	23	137	159	137	159	0.97
2	15	0.0022	0.11	13.1	1.8	3	23	167	187	165	187	0.94
3	15	0.00013	0.0064	17.0	0.1	1	23	323	345	323	345	0.98
4	15	0.00087	0.044	14.3	0.8	1	23	351	373	351	373	0.98
5	15	0.00027	0.014	16.0	4.0	1	23	403	425	403	425	0.97
6	15	0.00019	0.0099	16.4	0.5	1	23	449	471	449	471	0.95
7	15	0.016	0.8	10.4	1.6	1	23	477	500	477	500	0.97
8	15	0.037	1.9	9.2	0.4	3	19	509	525	508	526	0.95
9	15	0.00022	0.011	16.2	5.6	1	23	535	557	535	557	0.97
10	15	0.065	3.3	8.5	0.4	2	23	563	584	562	584	0.96
11	15	1.3e-05	0.00065	20.1	1.0	1	23	593	615	593	615	0.98
12	15	0.0014	0.074	13.6	0.1	3	23	623	643	621	643	0.97
13	15	7.7e-05	0.0039	17.6	0.5	1	23	649	671	649	672	0.95
14	15	2.1	1.1e+02	3.7	0.3	1	23	682	704	682	704	0.95
15	15	0.0073	0.37	11.4	0.3	1	23	1194	1216	1194	1216	0.97

Sequence Information

Coding Sequence: ATGAACAATCCCGGCTATGGCGGCATCCAATGGATACAGCAGCACCACGCCTCAGCGAGCGAAACAGAAGTGGACATACTGGAAAACGGCGCTGACACTGGCGACGGGGACGGGGATGGCGAACCAGCCACGGCGTATGCAACGGATGAGGATCTGGACCATATGGCGGCCGAGAATCTGATATTTATGGCGCGTGATGGCCAGCTGATGCTGGTCACAGCCGATGGTACGGTGGCCTACGCCGAGGCCTTTGACGATGAGGTGGTCACCGAGGAGGTCATTACAGATGACTGGGTGCAGCATCAGGGAGCAGAGCGGGTGGAGATTGCTGCTGATCAAATTGCTGGCACCAACAGTTCCCAGGAGCTGCTGGATATGGAGCAGGACGAGTACACGGCCTTGCGTCCCTATCCCTGTGATTTCTGCAGTCGTCGCTTTCGGAAAAAGGTCACCCTCAACAATCATATGCTTGCGCATCAAAACGATCGGCCACATCTGTGCAAGCTGTGTGGGGCCCGGTTCTCGCGTCGAAATGAACTCATTAGTCACTTTAAGGCTCATGCCGAGGCTCAGGATGCAGCCGATGCGGAGGCAGCAGCAGCAGCTTCCGCTTCATCAGTCAAATTCGAGCAGCAGCAGCATCGGCCATTGGAGGATCATTACTACGAGCAGGATTGGCCTATGTATCAGCAGGAATCGGAGCAGGTGCAGCAATCGAGCGAGTCTGCTGAAGTGGCGCAACAGCTAAGCTATTTGCCCGATGCCAGCCTAGAGTCGGCGGCTCCAGTTCCGTCGCGGGGCAGAATCAGTCGCCTGAAACCCAAGGAGGAGACCTCACAGTATATTGTGATTACCGAGGAGAATGTACAAAGTGAACCAGCTCAGCAAGAGGTACCCGAACCCGCTCCCAATGCCCCTTCCGAGGCTCTCCAACCCAAATTCCCCGTGCTGGATGAGAGTAAACCGTTTGTGTGCCAGCAGTGTGGCCTAGCCTTTGCGCGGGAGAAGGCTCTAGTCTCCCACATTAAGAATCACCGCGTGGACTCGCCTTTTGAATGCAACCAATGCCAGGAGATGTTCTGGGATAACAACAGCCTGCAGGAGCATCAGAAGACTCATCAGTTCGAGGAAAGCAACTCGGAGTATGACCCTGTCTCGGCAGAGGACAGTGGCAGCGAGTCGGAAACGGGACAGCTCTATGGAGAATTCTATTGCAGCGAATGTGGCATTTCCTTTCACAGGCAGGACCTACTCCATCGTCATGCCAAACAGCATTTCAAGTCACCAGCTGATCAGTCCGAGGCATTAGCTCCCACAGCAGCGGAAAATGCCCAAGATGCTTCTCACAGTTGTCACACCTGTGGCAAATCCTTTCCCAGTGCTCTTGAGCTGCTAGCCCATGCCGAGATTCATGCCCGTTTCCCGCCCTTCAAATGTGTTTTGTGTGGCATGAGCTTCTATGAGGAACAGGCCATTAAACGTCACTTGCACACCCGCCATCCGCACGAACTGAAGCCCAACTCCTGTGTCCTGTGTGGCAAGGAGTGCCGCGATCGCAAGGCCCTCATCAAGCACGCCTGGGATCACTCGCGTGAGAAGTGCCACTCGTGTTCCAAGTGTGGCAAGAATTTCCACAATAAGGCAAGGCTGAAGCGTCACATGGCCTCGCATCGCGACAAGTCGGTGGTCTGCGAGGTGTGCCAAGAGGAGTTCCCCGACGGGCGCACTCTCTCCAATCACCGACACTCGCATAGCACCACCTCGCCCGGTAAACTCTTCCCCTGCCATGAGTGCGGCAAAACGTTCGGCTCGCGCAGCTCCCAGCAGATCCACGTGCGCATCCACACGGGCGAACGTCCATACGGCTGTCGTTACTGCTGGAAGGCATTTGCCGATGGCGGCACTTTGCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTACGCCTGTTCGGTCTGCCCGCGTGCATTCAATCAGCGTGTGGTGCTCCGTGAGCACATTCGTTCCCATCACTCGGGCCTGGATGTGGCAAGGGGCACGTACCACTGCACCGTCTGCTCGGACGATTTACCCTCCTCCAATGATTTGATTCAGCATCTCATCCAGCATAGTGACAGCAACACGGCCAAACAGCGGCAGCCAATCACTGGTCCGCGCAAATACAAACGTCGACGCAAACTGCAACCACATGAAATAGCCCACATGCGTGCCGAACATAAAGACGCTGCCATTACCGATGAGGGATTGGGTGAGGGGGAGGAATATGCCAGCGATATAGATATCTGCGATTTTGATGTGGAAAATGTGGACGATCTTTTTGATATGGCCGAGTCAACGCCAAAAAAAGGAAAGGGCAAAAAGGGTGCGTCTAAGGACTGCCACAAGCCAGTGGTCAATGGAGCAGTCAAGCCAGTACAGGACAAGTCCAAGCAGCGCTGCGATTCCCAAAGCAGCCAATCGGATCGTATGTGGGAGGAGAAGTTCCTGCAGGATAGCCAGGTGGCGTTCTTTCAAATCGACTCGTTGGTTGTGGTTAATGACACAACACTGCAACCTGCCTCTTCGGCTGCTCCTTCTGTGACGACAAAAACGCGACGTGCAGCAAAGCAGCCGGCTCAGGGTCAGGATCAGGCCAAGGAGCCATCTCCAGTAGCGGGTAAAACCGCCTCGGCCACCACTAACTCCAGCAGCCGTAGCAGAAAAAAGACGACCACTAAAGCTGCTTCCGCTGTTAGTTCGCGTCCGCGCATGATTCACACTGAGAAGGCAAAGATTCCTAAGGCCACCGAAAGTTCCAAAAAGACGAGGTCAAAGACCTACATAACCCGCACGGAGACCACCAACAACTTGGCTTCGCGGACCGCTCCCTCCTCTTCCAACATTGTCGATGACTATGAGATTATTTCACCAGCCACACAGCCACCAAATCAGATCAGCTCTAGTCCCTTGCATATCAAGCAGGAGCAAGAGCAGCAACGGGTCCAATTGATGTACGATGACACTCTTCTCATAGATGCCGCACTGCTTCGCGAGAAGACCTATGAAAAGTTCAATCCCAGTATAGTCAATGATCTGGAGGAAATCTTACGCTCACCGCTCAAACATGATCGCAATGCCCGCCTGCGCTTCACCAGCGAGTCCTCGACGACGCCGCAATTCCTGCCGGAGGAGGAACAAAACCTCATCAAAATCGAACCCACTTCACCCGATCTTCGTGAAATGGTTTCGACAGGTGGCGCTGGAGCCACACCCAGTTCCTCAGCGGCTCGCACCTCGCGGCATCTTCGCCAGCTCACTGCTAATAGCTCACGGGTGGGCAGCAAACGGACGAGCAGCAGCAAGCCTGCCCCCTCCACCAGTTCCAGCGCTGCCAAGAAATCAAGCAAGGCCAGCAACTCCTACCTCAGCTACGGCGTGGGCGTAGACGCCTACAATGTGAATGTACCTGCCGGCGCCAGCACTGCCGATGTGAGTTCCGGTTTCTTCTCAATCTCCGAGGTGGTGTCCGCCGCGGATGCTGCCGATGCGGCGGCTAAGGCAGCCGCTGCTAGTAAACCCGAGCGGAAGACGCGTAGCTTTGAGTGCGAAATGTGCTCGGCCATTTTCTATGATCGCGGCCAGTTGCTGGAACATGTTCACATTCACATCTAG
Protein Sequence: MNNPGYGGIQWIQQHHASASETEVDILENGADTGDGDGDGEPATAYATDEDLDHMAAENLIFMARDGQLMLVTADGTVAYAEAFDDEVVTEEVITDDWVQHQGAERVEIAADQIAGTNSSQELLDMEQDEYTALRPYPCDFCSRRFRKKVTLNNHMLAHQNDRPHLCKLCGARFSRRNELISHFKAHAEAQDAADAEAAAAASASSVKFEQQQHRPLEDHYYEQDWPMYQQESEQVQQSSESAEVAQQLSYLPDASLESAAPVPSRGRISRLKPKEETSQYIVITEENVQSEPAQQEVPEPAPNAPSEALQPKFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNNSLQEHQKTHQFEESNSEYDPVSAEDSGSESETGQLYGEFYCSECGISFHRQDLLHRHAKQHFKSPADQSEALAPTAAENAQDASHSCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGMSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARGTYHCTVCSDDLPSSNDLIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDAAITDEGLGEGEEYASDIDICDFDVENVDDLFDMAESTPKKGKGKKGASKDCHKPVVNGAVKPVQDKSKQRCDSQSSQSDRMWEEKFLQDSQVAFFQIDSLVVVNDTTLQPASSAAPSVTTKTRRAAKQPAQGQDQAKEPSPVAGKTASATTNSSSRSRKKTTTKAASAVSSRPRMIHTEKAKIPKATESSKKTRSKTYITRTETTNNLASRTAPSSSNIVDDYEIISPATQPPNQISSSPLHIKQEQEQQRVQLMYDDTLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVSTGGAGATPSSSAARTSRHLRQLTANSSRVGSKRTSSSKPAPSTSSSAAKKSSKASNSYLSYGVGVDAYNVNVPAGASTADVSSGFFSISEVVSAADAADAAAKAAAASKPERKTRSFECEMCSAIFYDRGQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00914679;
90% Identity: iTF_00918364;
80% Identity: -