Basic Information

Insect: Lomographa bimaculata
Gene Symbol: ZEB1
Assembly: GCA_948107665.1
Location: OX403613.1:5631208-5645780[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0022 0.15 12.9 2.1 1 23 355 377 355 377 0.99

2 11 0.029 2 9.4 0.8 1 23 411 433 411 433 0.96

3 11 1.5e-05 0.001 19.8 1.5 1 23 438 461 438 461 0.98

4 11 0.15 10 7.1 0.8 3 23 467 488 466 488 0.94

5 11 0.0057 0.39 11.7 0.1 2 20 497 515 496 517 0.93

6 11 0.00043 0.029 15.2 0.4 3 23 526 546 526 546 0.98

7 11 0.0014 0.097 13.5 0.0 3 23 553 574 551 574 0.95

8 11 0.00063 0.043 14.7 0.6 2 23 584 605 584 605 0.97

9 11 1.9e-05 0.0013 19.5 0.3 1 23 611 633 611 633 0.98

10 11 1.3e-05 0.00086 20.0 0.6 1 23 639 661 639 661 0.97

11 11 6.4e-05 0.0043 17.8 1.1 1 19 667 685 667 690 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0022	0.15	12.9	2.1	1	23	355	377	355	377	0.99
2	11	0.029	2	9.4	0.8	1	23	411	433	411	433	0.96
3	11	1.5e-05	0.001	19.8	1.5	1	23	438	461	438	461	0.98
4	11	0.15	10	7.1	0.8	3	23	467	488	466	488	0.94
5	11	0.0057	0.39	11.7	0.1	2	20	497	515	496	517	0.93
6	11	0.00043	0.029	15.2	0.4	3	23	526	546	526	546	0.98
7	11	0.0014	0.097	13.5	0.0	3	23	553	574	551	574	0.95
8	11	0.00063	0.043	14.7	0.6	2	23	584	605	584	605	0.97
9	11	1.9e-05	0.0013	19.5	0.3	1	23	611	633	611	633	0.98
10	11	1.3e-05	0.00086	20.0	0.6	1	23	639	661	639	661	0.97
11	11	6.4e-05	0.0043	17.8	1.1	1	19	667	685	667	690	0.95

Sequence Information

Coding Sequence: ATGGATAATATAATGGCCTGCAGAATTTGCCTTGCGACAGATGTCAAACTTTACGATATGTGCAAATATCGCCTCAAAACTGCCTACGAGGTTCTAACTGGATTTAATATGACTGACGACTACCTTCATCACATATGTGCTTATTGCGGAGCCCTATTAAACAAGTATGCGATGTTCCGGAAGAGGTGCTCTCGCACACAACAATTTCTAGAGCTGTTATTGGCTGAACATGtactggtttgtattttacttgcaatgtttGTAACTACAGACCAAATAAGAGAAATAAACCAAACACTGCCGAACATTTCACACCCTTACACAATGCAATATATTGATTTCTACGACTCTACTGTTAAAATAAAAGACGAATTTTACGAAGACAGCATAACTCCCAATGACAATAATATAAATGAAGACTCAAACACAAATGAAGACCTTAAAACAAATGAAGACATAAAAACAAATGATGACATAAATACAAATGAGGACAAACATAAAAATGAGGTCATACTTACAAATGAAAACACAAATACAATTGAAGATATTGAAGTCCACTACTACAATACATCAAATAATGCTCTAATTAGTAGTATTGTTAATGTGGGAAATATCTACACAGAATCGGAAAGTGACGAAGAACCGCTATCGAAAAAACAAAATATGATCAAAAAAATTAAATGTAACAACGTAAATGATTCTGAACAAAGTGATTACGACAACAATCCAGTTTCAAAAAAATTGGGGTATAACGATATTGATAAAGATTCTGATATAAATTACTCAAGACACGATTATAGAGCAGATGATACTGATTCCGATTATTCACTCAAAAATGACAAAAATGATTCCGACACAGATGATTCTAAGAAAGAAAGAGAGAGACAGTCAATTAACCAACCAAAAAGGTCTAAGATAAAAAATCTTGAAAAATATTTAAGAAGAAACAAAGTTGTCATTCATAATGAAGAAATAGAACATAAAGTTATTATTCTTAATAAAGAAGATCAAATAAAAGAGGTTACGGCAAGGAAGGATTCATTTAAGTATAAGAATGCCGTTTATAAATGTGATAGTTGTTTCAAAGGTTTTACGATGACAGTTTCATACAAGAATCATATGATAAGGCATGACCCGGTCTCAGGCCCGATTGTTTGCGACATTTGCCGCATGCGATGGCCCGATATACGCGCCTTGCGAGCGCATAGTCTCATGTCGCATGAAAGGAAGTATATATGCAAAATATGCGGGCATATATCAAAAACAGCTCATAAAGCGAGAGAGCACATCGCGTGGCACAGAGGAGCGAGTTTCACGTGCAAACTTTGCGGGGCCACGTTCAGCAAAAACACCAGCTATCTAACGCACATGAGGATACAGCATCCGACTAAGAATATTTGCAGTCACTGCGGGTTAAGCTTTTTAGGCGAGAAAGGGTTAGAAATGCACAGGAAGAAGGTGCATCTAGTTGAGGGTGATGAAATAGATGAGTGTAATGTCTGTCGACTACGGTTCGACAATAAAGACGCGTTGGTTCGTCATAAGGAACTAGGATGTGACGTTAAATTAAAGTGGTGTTTACAATGCGGCGAGCAGTTCACCACGGCAGGTGACATTAAGACTCATATGAAATCTCACGTCAAACGGAGAGTGAACTGTGATGAGTGTCCGCGAACGTTCGCGCTCGCTCGCCTGCTCACCGCTCATGTGTTACGTGTGCATCGCAAGCAACTGCCGAAATCTGGTGGCGTTTGCGAACTCTGCGGCGTTTACTGTGAGAGCCGTTCGTCGTTGATAAACCATCAGAGAATCCACAGCGGGGAGAAGCCCTACGCTTGCGGCGTTTGCGACAAGAGATTCAGGGTGCTGCAACTGCTGCAGATACACACACGTACCCACACAGGGGAAAGGCCGTTTGCTTGCAGTCGCTGCCCCAAAGCCTTCGTTCATAAGGCGGGACTAAACAGACATGAACGTGTGCATACCGGAGCGAAGCCCTACATTTGTCCTCAATGCGGCAAGTCCTTTTCGCAATCAAACTCCATGAAACAGCACTGCGCAGGAGTCCATATGAAAAAGTACTTGTATTCTCGACGAGCGGCGAATAAACAGACTAGTTTAATGTAA
Protein Sequence: MDNIMACRICLATDVKLYDMCKYRLKTAYEVLTGFNMTDDYLHHICAYCGALLNKYAMFRKRCSRTQQFLELLLAEHVLVCILLAMFVTTDQIREINQTLPNISHPYTMQYIDFYDSTVKIKDEFYEDSITPNDNNINEDSNTNEDLKTNEDIKTNDDINTNEDKHKNEVILTNENTNTIEDIEVHYYNTSNNALISSIVNVGNIYTESESDEEPLSKKQNMIKKIKCNNVNDSEQSDYDNNPVSKKLGYNDIDKDSDINYSRHDYRADDTDSDYSLKNDKNDSDTDDSKKERERQSINQPKRSKIKNLEKYLRRNKVVIHNEEIEHKVIILNKEDQIKEVTARKDSFKYKNAVYKCDSCFKGFTMTVSYKNHMIRHDPVSGPIVCDICRMRWPDIRALRAHSLMSHERKYICKICGHISKTAHKAREHIAWHRGASFTCKLCGATFSKNTSYLTHMRIQHPTKNICSHCGLSFLGEKGLEMHRKKVHLVEGDEIDECNVCRLRFDNKDALVRHKELGCDVKLKWCLQCGEQFTTAGDIKTHMKSHVKRRVNCDECPRTFALARLLTAHVLRVHRKQLPKSGGVCELCGVYCESRSSLINHQRIHSGEKPYACGVCDKRFRVLQLLQIHTRTHTGERPFACSRCPKAFVHKAGLNRHERVHTGAKPYICPQCGKSFSQSNSMKQHCAGVHMKKYLYSRRAANKQTSLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -